Works matching AU Kwan, Cynthia

Results: 19

5-HT2A blockade for dyskinesia and psychosis in Parkinson's disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review.

Published in:

Experimental Brain Research, 2019, v. 237, n. 2, p. 435, doi. 10.1007/s00221-018-5434-9

By:

Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Nuara, Stephen G.;
Gourdon, Jim C.;
Hamadjida, Adjia;
Huot, Philippe

Publication type:

Article

Effect of the selective 5-HT2A receptor antagonist EMD-281,014 on L-DOPA-induced abnormal involuntary movements in the 6-OHDA-lesioned rat.

Published in:

Experimental Brain Research, 2019, v. 237, n. 1, p. 29, doi. 10.1007/s00221-018-5390-4

By:

Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Belliveau, Sébastien;
Bourgeois-Cayer, Élodie;
Gaudette, Fleur;
Beaudry, Francis;
Hamadjida, Adjia;
Huot, Philippe

Publication type:

Article

Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Published in:

Journal of Neural Transmission, 2021, v. 128, n. 1, p. 73, doi. 10.1007/s00702-020-02287-8

By:

Frouni, Imane;
Kwan, Cynthia;
Nuara, Stephen G.;
Belliveau, Sébastien;
Kang, Woojin;
Hamadjida, Adjia;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Combined mGlu2 orthosteric stimulation and positive allosteric modulation alleviates l-DOPA-induced psychosis-like behaviours and dyskinesia in the parkinsonian marmoset.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 7, p. 1023, doi. 10.1007/s00702-020-02185-z

By:

Nuara, Stephen G.;
Hamadjida, Adjia;
Kwan, Cynthia;
Bédard, Dominique;
Frouni, Imane;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

[3H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain.

Published in:

Experimental Brain Research, 2024, v. 242, n. 5, p. 1203, doi. 10.1007/s00221-024-06815-w

By:

Frouni, Imane;
Kim, Esther;
Shaqfah, Judy;
Bédard, Dominique;
Kwan, Cynthia;
Belliveau, Sébastien;
Huot, Philippe

Publication type:

Article

Effect of the mGlu4 positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.

Published in:

Psychopharmacology, 2023, v. 240, n. 10, p. 2093, doi. 10.1007/s00213-023-06428-1

By:

Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Kang, Woojin;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.

Published in:

Psychopharmacology, 2017, v. 234, n. 6, p. 905, doi. 10.1007/s00213-017-4530-z

By:

Hamadjida, Adjia;
Nuara, Stephen;
Veyres, Nicolas;
Frouni, Imane;
Kwan, Cynthia;
Sid-Otmane, Lamia;
Harraka, Mery-Jane;
Gourdon, Jim;
Huot, Philippe

Publication type:

Article

Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32871-3

By:

Feng, Tianshi;
Zhao, Xuemei;
Gu, Ping;
Yang, Wah;
Wang, Cunchuan;
Guo, Qingyu;
Long, Qiaoyun;
Liu, Qing;
Cheng, Ying;
Li, Jin;
Cheung, Cynthia Kwan Yui;
Wu, Donghai;
Kong, Xinyu;
Xu, Yong;
Ye, Dewei;
Hua, Shuang;
Loomes, Kerry;
Xu, Aimin;
Hui, Xiaoyan

Publication type:

Article

Serum Thrombospondin-2 Levels Are Closely Associated With the Severity of Metabolic Syndrome and Metabolic Associated Fatty Liver Disease.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 8, p. e3230, doi. 10.1210/clinem/dgac292

By:

Xuerui Wu;
Yui Cheung, Cynthia Kwan;
Dewei Ye;
Chakrabarti, Subrata;
Mahajan, Hema;
Sen Yan;
Erfei Song;
Wah Yang;
Chi Ho Lee;
Ling Lam, Karen Siu;
Cunchuan Wang;
Aimin Xu

Publication type:

Article

Effect of mGluR2 and mGluR2/3 activators on parkinsonism in the MPTP-lesioned non-human primate.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 11, p. 9135, doi. 10.1007/s00210-024-03216-2

By:

Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Hamadjida, Adjia;
Kang, Woojin;
Belliveau, Sébastien;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Positive allosteric mGluR2 modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 11, p. 8917, doi. 10.1007/s00210-024-03215-3

By:

Kang, Woojin;
Frouni, Imane;
Bédard, Dominique;
Kwan, Cynthia;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The mGluR2/3 orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023, v. 396, n. 10, p. 2347, doi. 10.1007/s00210-023-02587-2

By:

Kang, Woojin;
Nuara, Stephen G.;
Bédard, Dominique;
Frouni, Imane;
Kwan, Cynthia;
Hamadjida, Adjia;
Gourdon, Jim C.;
Gaudette, Fleur;
Beaudry, Francis;
Huot, Philippe

Publication type:

Article

Further characterisation of psychosis-like behaviours induced by L-DOPA in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2021, v. 394, n. 8, p. 1685, doi. 10.1007/s00210-021-02090-6

By:

Kwan, Cynthia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 11, p. 2139, doi. 10.1007/s00210-020-01927-w

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Monoamine oxidase A inhibition with moclobemide enhances the anti-parkinsonian effect of L-DOPA in the MPTP-lesioned marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 11, p. 2157, doi. 10.1007/s00210-020-01933-y

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Nefazodone reduces dyskinesia, but not psychosis-like behaviours, in the parkinsonian marmoset.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2018, v. 391, n. 12, p. 1339, doi. 10.1007/s00210-018-1549-6

By:

Hamadjida, Adjia;
Nuara, Stephen G.;
Bédard, Dominique;
Frouni, Imane;
Kwan, Cynthia;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

Effect of the mGlu2 positive allosteric modulator biphenyl‐indanone A as a monotherapy and as adjunct to a low dose of L‐DOPA in the MPTP‐lesioned marmoset.

Published in:

European Journal of Neuroscience, 2024, v. 60, n. 9, p. 6175, doi. 10.1111/ejn.16454

By:

Kang, Woojin;
Frouni, Imane;
Kwan, Cynthia;
Bédard, Dominique;
Nuara, Stephen G.;
Hamadjida, Adjia;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The 5‐HT2A/2C inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset.

Published in:

European Journal of Neuroscience, 2024, v. 59, n. 6, p. 1169, doi. 10.1111/ejn.16104

By:

Kwan, Cynthia;
Frouni, Imane;
Bédard, Dominique;
Hamadjida, Adjia;
Nuara, Stephen G.;
Gourdon, Jim C.;
Huot, Philippe

Publication type:

Article

The highly selective mGlu2 receptor positive allosteric modulator LY‐487,379 alleviates l‐DOPA‐induced dyskinesia in the 6‐OHDA‐lesioned rat model of Parkinson's disease.

Published in:

European Journal of Neuroscience, 2020, v. 51, n. 12, p. 2412, doi. 10.1111/ejn.14679

By:

Hamadjida, Adjia;
Sid‐Otmane, Lamia;
Kwan, Cynthia;
Frouni, Imane;
Nafade, Vaidehi;
Bédard, Dominique;
Gagnon, Dave;
Wallman, Marie‐Josée;
Rouillard, Claude;
Parent, André;
Parent, Martin;
Huot, Philippe

Publication type:

Article

Works matching AU Kwan, Cynthia

5-HT<sub>2A</sub> blockade for dyskinesia and psychosis in Parkinson's disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review.

Effect of the selective 5-HT<sub>2A</sub> receptor antagonist EMD-281,014 on L-DOPA-induced abnormal involuntary movements in the 6-OHDA-lesioned rat.

Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Combined mGlu2 orthosteric stimulation and positive allosteric modulation alleviates l-DOPA-induced psychosis-like behaviours and dyskinesia in the parkinsonian marmoset.

[<sup>3</sup>H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain.

Effect of the mGlu<sub>4</sub> positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset.

The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.

Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.

Serum Thrombospondin-2 Levels Are Closely Associated With the Severity of Metabolic Syndrome and Metabolic Associated Fatty Liver Disease.

Effect of mGluR<sub>2</sub> and mGluR<sub>2/3</sub> activators on parkinsonism in the MPTP-lesioned non-human primate.

Positive allosteric mGluR<sub>2</sub> modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset.

The mGluR<sub>2/3</sub> orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

Further characterisation of psychosis-like behaviours induced by L-DOPA in the MPTP-lesioned marmoset.

Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset.

Monoamine oxidase A inhibition with moclobemide enhances the anti-parkinsonian effect of L-DOPA in the MPTP-lesioned marmoset.

Nefazodone reduces dyskinesia, but not psychosis-like behaviours, in the parkinsonian marmoset.

Effect of the mGlu<sub>2</sub> positive allosteric modulator biphenyl‐indanone A as a monotherapy and as adjunct to a low dose of L‐DOPA in the MPTP‐lesioned marmoset.

The 5‐HT<sub>2A/2C</sub> inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset.

The highly selective mGlu<sub>2</sub> receptor positive allosteric modulator LY‐487,379 alleviates l‐DOPA‐induced dyskinesia in the 6‐OHDA‐lesioned rat model of Parkinson's disease.