Works by Kushima, Itaru

Results: 86
    1

    Proposal for a Novel Classification of Patients With Enlarged Ventricles and Cognitive Impairment Based on Data‐Driven Analysis of Neuroimaging Results in Patients With Psychiatric Disorders.

    Published in:
    Neuropsychopharmacology Reports, 2025, v. 45, n. 1, p. 1, doi. 10.1002/npr2.70010
    By:
    • Yasuda, Yuka;
    • Ito, Satsuki;
    • Matsumoto, Junya;
    • Okada, Naohiro;
    • Onitsuka, Toshiaki;
    • Ikeda, Masashi;
    • Kushima, Itaru;
    • Sumiyoshi, Chika;
    • Fukunaga, Masaki;
    • Nemoto, Kiyotaka;
    • Miura, Kenichiro;
    • Hashimoto, Naoki;
    • Ohi, Kazutaka;
    • Takahashi, Tsutomu;
    • Sasabayashi, Daiki;
    • Koeda, Michihiko;
    • Yamamori, Hidenaga;
    • Fujimoto, Michiko;
    • Takano, Harumasa;
    • Hasegawa, Naomi
    Publication type:
    Article
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    Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case–control study.

    Published in:
    Neuropsychopharmacology Reports, 2024, v. 44, n. 1, p. 42, doi. 10.1002/npr2.12370
    By:
    • Lo, Tzuyao;
    • Kushima, Itaru;
    • Kimura, Hiroki;
    • Aleksic, Branko;
    • Okada, Takashi;
    • Kato, Hidekazu;
    • Inada, Toshiya;
    • Nawa, Yoshihiro;
    • Torii, Youta;
    • Yamamoto, Maeri;
    • Kimura, Ryo;
    • Funabiki, Yasuko;
    • Kosaka, Hirotaka;
    • Numata, Shusuke;
    • Kasai, Kiyoto;
    • Sasaki, Tsukasa;
    • Yokoyama, Shigeru;
    • Munesue, Toshio;
    • Hashimoto, Ryota;
    • Yasuda, Yuka
    Publication type:
    Article
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    Identification of ultra-rare disruptive variants in voltage-gated calcium channel-encoding genes in Japanese samples of schizophrenia and autism spectrum disorder.

    Published in:
    Translational Psychiatry, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41398-022-01851-y
    By:
    • Wang, Chenyao;
    • Horigane, Shin-ichiro;
    • Wakamori, Minoru;
    • Ueda, Shuhei;
    • Kawabata, Takeshi;
    • Fujii, Hajime;
    • Kushima, Itaru;
    • Kimura, Hiroki;
    • Ishizuka, Kanako;
    • Nakamura, Yukako;
    • Iwayama, Yoshimi;
    • Ikeda, Masashi;
    • Iwata, Nakao;
    • Okada, Takashi;
    • Aleksic, Branko;
    • Mori, Daisuke;
    • Yoshida, Takashi;
    • Bito, Haruhiko;
    • Yoshikawa, Takeo;
    • Takemoto-Kimura, Sayaka
    Publication type:
    Article
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    Structural diverseness of neurons between brain areas and between cases.

    Published in:
    Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-020-01173-x
    By:
    • Mizutani, Ryuta;
    • Saiga, Rino;
    • Yamamoto, Yoshiro;
    • Uesugi, Masayuki;
    • Takeuchi, Akihisa;
    • Uesugi, Kentaro;
    • Terada, Yasuko;
    • Suzuki, Yoshio;
    • De Andrade, Vincent;
    • De Carlo, Francesco;
    • Takekoshi, Susumu;
    • Inomoto, Chie;
    • Nakamura, Naoya;
    • Torii, Youta;
    • Kushima, Itaru;
    • Iritani, Shuji;
    • Ozaki, Norio;
    • Oshima, Kenichi;
    • Itokawa, Masanari;
    • Arai, Makoto
    Publication type:
    Article
    10

    Rare genetic variants in the gene encoding histone lysine demethylase 4C (KDM4C) and their contributions to susceptibility to schizophrenia and autism spectrum disorder.

    Published in:
    Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-01107-7
    By:
    • Kato, Hidekazu;
    • Kushima, Itaru;
    • Mori, Daisuke;
    • Yoshimi, Akira;
    • Aleksic, Branko;
    • Nawa, Yoshihiro;
    • Toyama, Miho;
    • Furuta, Sho;
    • Yu, Yanjie;
    • Ishizuka, Kanako;
    • Kimura, Hiroki;
    • Arioka, Yuko;
    • Tsujimura, Keita;
    • Morikawa, Mako;
    • Okada, Takashi;
    • Inada, Toshiya;
    • Nakatochi, Masahiro;
    • Shinjo, Keiko;
    • Kondo, Yutaka;
    • Kaibuchi, Kozo
    Publication type:
    Article
    11

    Common Variants in BCL9 Gene and Schizophrenia in a Japanese Population: Association Study, Meta-Analysis and Cognitive Function Analysis / UOBIČAJENE VARIJANTE BCL9 GENA I ŠIZOFRENIJA U JAPANSKOJ POPULACIJI: ŠTUDIJA POVEZANOSTI, METAANALIZA I ANALIZA KOGNITIVNIH FUNKCIJA

    Published in:
    Journal of Medical Biochemistry, 2013, v. 32, n. 4, p. 361, doi. 10.2478/jomb-2013-0049
    By:
    • Shiino, Tomoko;
    • Koide, Takayoshi;
    • Kushima, Itaru;
    • Ikeda, Masashi;
    • Kunimoto, Shohko;
    • Nakamura, Yukako;
    • Yoshimi, Akira;
    • Aleksic, Branko;
    • Banno, Masahiro;
    • Kikuchi, Tsutomu;
    • Kohmura, Kunihiro;
    • Adachi, Yasunori;
    • Kawano, Naoko;
    • Okada, Takashi;
    • Inada, Toshiya;
    • Ujike, Hiroshi;
    • Iidaka, Tetsuya;
    • Suzuki, Michio;
    • Iwata, Nakao;
    • Ozaki, Norio
    Publication type:
    Article
    12

    Structural aging of human neurons is opposite of the changes in schizophrenia.

    Published in:
    PLoS ONE, 2023, v. 18, n. 6, p. 1, doi. 10.1371/journal.pone.0287646
    By:
    • Mizutani, Ryuta;
    • Saiga, Rino;
    • Yamamoto, Yoshiro;
    • Uesugi, Masayuki;
    • Takeuchi, Akihisa;
    • Uesugi, Kentaro;
    • Terada, Yasuko;
    • Suzuki, Yoshio;
    • De Andrade, Vincent;
    • De Carlo, Francesco;
    • Takekoshi, Susumu;
    • Inomoto, Chie;
    • Nakamura, Naoya;
    • Torii, Youta;
    • Kushima, Itaru;
    • Iritani, Shuji;
    • Ozaki, Norio;
    • Oshima, Kenichi;
    • Itokawa, Masanari;
    • Arai, Makoto
    Publication type:
    Article
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    Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

    Published in:
    Schizophrenia Bulletin, 2019, v. 45, n. 4, p. 824, doi. 10.1093/schbul/sby140
    By:
    • Ikeda, Masashi;
    • Takahashi, Atsushi;
    • Kamatani, Yoichiro;
    • Momozawa, Yukihide;
    • Saito, Takeo;
    • Kondo, Kenji;
    • Shimasaki, Ayu;
    • Kawase, Kohei;
    • Sakusabe, Takaya;
    • Iwayama, Yoshimi;
    • Toyota, Tomoko;
    • Wakuda, Tomoyasu;
    • Kikuchi, Mitsuru;
    • Kanahara, Nobuhisa;
    • Yamamori, Hidenaga;
    • Yasuda, Yuka;
    • Watanabe, Yuichiro;
    • Hoya, Satoshi;
    • Aleksic, Branko;
    • Kushima, Itaru
    Publication type:
    Article
    16
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    Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes.

    Published in:
    Translational Psychiatry, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41398-022-02033-6
    By:
    • Kimura, Hiroki;
    • Nakatochi, Masahiro;
    • Aleksic, Branko;
    • Guevara, James;
    • Toyama, Miho;
    • Hayashi, Yu;
    • Kato, Hidekazu;
    • Kushima, Itaru;
    • Morikawa, Mako;
    • Ishizuka, Kanako;
    • Okada, Takashi;
    • Tsurusaki, Yoshinori;
    • Fujita, Atsushi;
    • Miyake, Noriko;
    • Ogi, Tomoo;
    • Takata, Atsushi;
    • Matsumoto, Naomichi;
    • Buxbaum, Joseph;
    • Ozaki, Norio;
    • Sebat, Jonathan
    Publication type:
    Article
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    De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues.

    Published in:
    Human Genetics, 2023, v. 142, n. 7, p. 949, doi. 10.1007/s00439-023-02569-7
    By:
    • Smits, Daphne J.;
    • Schot, Rachel;
    • Popescu, Cristiana A.;
    • Dias, Kerith-Rae;
    • Ades, Lesley;
    • Briere, Lauren C.;
    • Sweetser, David A.;
    • Kushima, Itaru;
    • Aleksic, Branko;
    • Khan, Suliman;
    • Karageorgou, Vasiliki;
    • Ordonez, Natalia;
    • Sleutels, Frank J. G. T.;
    • van der Kaay, Daniëlle C. M.;
    • Van Mol, Christine;
    • Van Esch, Hilde;
    • Bertoli-Avella, Aida M.;
    • Roscioli, Tony;
    • Mancini, Grazia M. S.
    Publication type:
    Article
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    Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons.

    Published in:
    Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00735-4
    By:
    • Hada, Kazuhiro;
    • Wulaer, Bolati;
    • Nagai, Taku;
    • Itoh, Norimichi;
    • Sawahata, Masahito;
    • Sobue, Akira;
    • Mizoguchi, Hiroyuki;
    • Mori, Daisuke;
    • Kushima, Itaru;
    • Nabeshima, Toshitaka;
    • Ozaki, Norio;
    • Yamada, Kiyofumi
    Publication type:
    Article
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    Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature.

    Published in:
    Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02952-6
    By:
    • Mori, Daisuke;
    • Inami, Chihiro;
    • Ikeda, Ryosuke;
    • Sawahata, Masahito;
    • Urata, Shinji;
    • Yamaguchi, Sho T.;
    • Kobayashi, Yohei;
    • Fujita, Kosuke;
    • Arioka, Yuko;
    • Okumura, Hiroki;
    • Kushima, Itaru;
    • Kodama, Akiko;
    • Suzuki, Toshiaki;
    • Hirao, Takashi;
    • Yoshimi, Akira;
    • Sobue, Akira;
    • Ito, Takahiro;
    • Noda, Yukikiro;
    • Mizoguchi, Hiroyuki;
    • Nagai, Taku
    Publication type:
    Article
    28

    Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice.

    Published in:
    Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-023-02679-w
    By:
    • Mori, Daisuke;
    • Ikeda, Ryosuke;
    • Sawahata, Masahito;
    • Yamaguchi, Sho;
    • Kodama, Akiko;
    • Hirao, Takashi;
    • Arioka, Yuko;
    • Okumura, Hiroki;
    • Inami, Chihiro;
    • Suzuki, Toshiaki;
    • Hayashi, Yu;
    • Kato, Hidekazu;
    • Nawa, Yoshihiro;
    • Miyata, Seiko;
    • Kimura, Hiroki;
    • Kushima, Itaru;
    • Aleksic, Branko;
    • Mizoguchi, Hiroyuki;
    • Nagai, Taku;
    • Nakazawa, Takanobu
    Publication type:
    Article
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    A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders.

    Published in:
    Annals of Clinical & Translational Neurology, 2020, v. 7, n. 7, p. 1117, doi. 10.1002/acn3.51093
    By:
    • Suzuki, Toshimitsu;
    • Suzuki, Toshifumi;
    • Raveau, Matthieu;
    • Miyake, Noriko;
    • Sudo, Genki;
    • Tsurusaki, Yoshinori;
    • Watanabe, Takaki;
    • Sugaya, Yuki;
    • Tatsukawa, Tetsuya;
    • Mazaki, Emi;
    • Shimohata, Atsushi;
    • Kushima, Itaru;
    • Aleksic, Branko;
    • Shiino, Tomoko;
    • Toyota, Tomoko;
    • Iwayama, Yoshimi;
    • Nakaoka, Kentaro;
    • Ohmori, Iori;
    • Sasaki, Aya;
    • Watanabe, Ken
    Publication type:
    Article
    31

    ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk.

    Published in:
    Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-00917-z
    By:
    • Sekiguchi, Mariko;
    • Sobue, Akira;
    • Kushima, Itaru;
    • Wang, Chenyao;
    • Arioka, Yuko;
    • Kato, Hidekazu;
    • Kodama, Akiko;
    • Kubo, Hisako;
    • Ito, Norimichi;
    • Sawahata, Masahito;
    • Hada, Kazuhiro;
    • Ikeda, Ryosuke;
    • Shinno, Mio;
    • Mizukoshi, Chikara;
    • Tsujimura, Keita;
    • Yoshimi, Akira;
    • Ishizuka, Kanako;
    • Takasaki, Yuto;
    • Kimura, Hiroki;
    • Xing, Jingrui
    Publication type:
    Article
    32

    Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus.

    Published in:
    Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-0723-z
    By:
    • Saito, Ryo;
    • Koebis, Michinori;
    • Nagai, Taku;
    • Shimizu, Kimiko;
    • Liao, Jingzhu;
    • Wulaer, Bolati;
    • Sugaya, Yuki;
    • Nagahama, Kenichiro;
    • Uesaka, Naofumi;
    • Kushima, Itaru;
    • Mori, Daisuke;
    • Maruyama, Kazuaki;
    • Nakao, Kazuki;
    • Kurihara, Hiroki;
    • Yamada, Kiyofumi;
    • Kano, Masanobu;
    • Fukada, Yoshitaka;
    • Ozaki, Norio;
    • Aiba, Atsu
    Publication type:
    Article
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    Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients.

    Published in:
    Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0461-2
    By:
    • Yoshimi, Akira;
    • Yamada, Shinnosuke;
    • Kunimoto, Shohko;
    • Aleksic, Branko;
    • Hirakawa, Akihiro;
    • Ohashi, Mitsuki;
    • Matsumoto, Yurie;
    • Hada, Kazuhiro;
    • Itoh, Norimichi;
    • Arioka, Yuko;
    • Kiumura, Hiroki;
    • Kushima, Itaru;
    • Nakamura, Yukako;
    • Shiino, Tomoko;
    • Mori, Daisuke;
    • Tanaka, Satoshi;
    • Hamada, Shuko;
    • Noda, Yukihiro;
    • Nagai, Taku;
    • Yamada, Kiyofumi
    Publication type:
    Article
    35

    Three-dimensional alteration of neurites in schizophrenia.

    Published in:
    Translational Psychiatry, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41398-019-0427-4
    By:
    • Mizutani, Ryuta;
    • Saiga, Rino;
    • Takeuchi, Akihisa;
    • Uesugi, Kentaro;
    • Terada, Yasuko;
    • Suzuki, Yoshio;
    • De Andrade, Vincent;
    • De Carlo, Francesco;
    • Takekoshi, Susumu;
    • Inomoto, Chie;
    • Nakamura, Naoya;
    • Kushima, Itaru;
    • Iritani, Shuji;
    • Ozaki, Norio;
    • Ide, Soichiro;
    • Ikeda, Kazutaka;
    • Oshima, Kenichi;
    • Itokawa, Masanari;
    • Arai, Makoto
    Publication type:
    Article
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    Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia.

    Published in:
    American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2016, v. 171B, n. 3, p. 447, doi. 10.1002/ajmg.b.32426
    By:
    • Higashiyama, Ryoko;
    • Ohnuma, Tohru;
    • Takebayashi, Yuto;
    • Hanzawa, Ryo;
    • Shibata, Nobuto;
    • Yamamori, Hidenaga;
    • Yasuda, Yuka;
    • Kushima, Itaru;
    • Aleksic, Branko;
    • Kondo, Kenji;
    • Ikeda, Masashi;
    • Hashimoto, Ryota;
    • Iwata, Nakao;
    • Ozaki, Norio;
    • Arai, Heii
    Publication type:
    Article
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    Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility.

    Published in:
    Schizophrenia Bulletin, 2015, v. 41, n. 3, p. 744, doi. 10.1093/schbul/sbu147
    By:
    • Hiroki Kimura;
    • Daisuke Tsuboi;
    • Chenyao Wang;
    • Itaru Kushima;
    • Takayoshi Koide;
    • Masashi Ikeda;
    • Yoshimi Iwayama;
    • Tomoko Toyota;
    • Noriko Yamamoto;
    • Shohko Kunimoto;
    • Yukako Nakamura;
    • Akira Yoshimi;
    • Masahiro Banno;
    • Jingrui Xing;
    • Yuto Takasaki;
    • Mami Yoshida;
    • Branko Aleksic;
    • Yota Uno;
    • Takashi Okada;
    • Tetsuya Iidaka
    Publication type:
    Article
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    Analysis of the VAV3 as Candidate Gene for Schizophrenia: Evidences From Voxel-Based Morphometry and Mutation Screening.

    Published in:
    Schizophrenia Bulletin, 2013, v. 39, n. 3, p. 720, doi. 10.1093/schbul/sbs038
    By:
    • Aleksic, Branko;
    • Kushima, Itaru;
    • Hashimoto, Ryota;
    • Ohi, Kazutaka;
    • Ikeda, Masashi;
    • Yoshimi, Akira;
    • Nakamura, Yukako;
    • Ito, Yoshihito;
    • Okochi, Tomo;
    • Fukuo, Yasuhisa;
    • Yasuda, Yuka;
    • Fukumoto, Motoyuki;
    • Yamamori, Hidenaga;
    • Ujike, Hiroshi;
    • Suzuki, Michio;
    • Inada, Toshiya;
    • Takeda, Masatoshi;
    • Kaibuchi, Kozo;
    • Iwata, Nakao;
    • Ozaki, Norio
    Publication type:
    Article
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    Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

    Published in:
    Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-017-0061-y
    By:
    • Yu, Yanjie;
    • Lin, Yingni;
    • Takasaki, Yuto;
    • Wang, Chenyao;
    • Kimura, Hiroki;
    • Xing, Jingrui;
    • Ishizuka, Kanako;
    • Toyama, Miho;
    • Kushima, Itaru;
    • Mori, Daisuke;
    • Arioka, Yuko;
    • Uno, Yota;
    • Shiino, Tomoko;
    • Nakamura, Yukako;
    • Okada, Takashi;
    • Morikawa, Mako;
    • Ikeda, Masashi;
    • Iwata, Nakao;
    • Okahisa, Yuko;
    • Takaki, Manabu
    Publication type:
    Article
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