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An optogenetic system for interrogating the temporal dynamics of Akt.
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- Scientific Reports, 2015, p. 14589, doi. 10.1038/srep14589
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- Article
Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data.
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- Genes to Cells, 2019, v. 24, n. 1, p. 82, doi. 10.1111/gtc.12655
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- Article
Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis.
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- Science Signaling, 2023, v. 16, n. 773, p. 1, doi. 10.1126/scisignal.abn0782
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- Article
Raf Kinase Inhibitory Protein is Required for Cerebellar Long-Term Synaptic Depression by Mediating PKC-Dependent MAPK Activation.
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- Journal of Neuroscience, 2012, v. 32, n. 41, p. 14254, doi. 10.1523/JNEUROSCI.2812-12.2012
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- Article
Analysis of Development of Direction Selectivity in Retinotectum by a Neural Circuit Model with Spike Timing-Dependent Plasticity.
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- Journal of Neuroscience, 2011, v. 31, n. 4, p. 1516, doi. 10.1523/JNEUROSCI.3811-10.2011
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Requirement of an Allosteric Kinetics of NMDA Receptors for Spike Timing-Dependent Plasticity.
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- Journal of Neuroscience, 2008, v. 28, n. 13, p. 3310, doi. 10.1523/JNEUROSCI.0303-08.2008
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- Article
Ca<sup>2+</sup>-independent phospholipase A2-dependent sustained Rho-kinase activation exhibits all-or-none response.
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- Genes to Cells, 2006, v. 11, n. 9, p. 1071, doi. 10.1111/j.1365-2443.2006.01001.x
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- Article
Phosphorylation of ERM proteins at filopodia induced by Cdc42.
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- Genes to Cells, 2000, v. 5, n. 7, p. 571, doi. 10.1046/j.1365-2443.2000.00348.x
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Statistical characteristics of climbing fiber spikes necessary for efficient cerebellar learning.
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- Biological Cybernetics, 2001, v. 84, n. 3, p. 183, doi. 10.1007/s004220000206
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Quantitative metabolic fluxes regulated by trans-omic networks.
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- Biochemical Journal, 2022, v. 479, n. 6, p. 787, doi. 10.1042/BCJ20210596
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A Conceptual Molecular Network for Chemotactic Behaviors Characterized by Feedback of Molecules Cycling Between the Membrane and the Cytosol.
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- Science Signaling, 2010, v. 3, n. 152, p. 1, doi. 10.1126/scisignal.2001056
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- Article
Decoupling of Receptor and Downstream Signals in the Akt Pathway by Its Low-Pass Filter Characteristics.
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- Science Signaling, 2010, v. 3, n. 132, p. 1, doi. 10.1126/scisignal.2000810
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Features extracted using tensor decomposition reflect the biological features of the temporal patterns of human blood multimodal metabolome.
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- PLoS ONE, 2023, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0281594
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- Article
Dynamic Characteristics of Transient Responses.
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- Journal of Biochemistry, 2005, v. 137, n. 6, p. 659, doi. 10.1093/jb/mvi084
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- Article
DI<sub>/cle</sub>, a Measure Consisting of Insulin Sensitivity, Secretion, and Clearance, Captures Diabetic States.
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- Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 12, p. 3080, doi. 10.1210/clinem/dgad392
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- Article
シグナル伝達機構による時間情報コード.
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- Seibutsu Butsuri, 2013, v. 53, n. 4, p. 184, doi. 10.2142/biophys.53.184
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A Mass Conserved ReactionDiffusion System Captures Properties of Cell Polarity.
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- PLoS Computational Biology, 2007, v. 3, n. 6, p. e108, doi. 10.1371/journal.pcbi.0030108
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- Article
Logical design of oral glucose ingestion pattern minimizing blood glucose in humans.
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- NPJ Systems Biology & Applications, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41540-019-0108-1
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Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects.
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- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0051-6
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Stochasticity in Ca<sup>2+</sup> Increase in Spines Enables Robust and Sensitive Information Coding.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099040
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The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0072780
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Temporal Decoding of MAP Kinase and CREB Phosphorylation by Selective Immediate Early Gene Expression.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057037
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A quantitative image cytometry technique for time series or population analyses of signaling networks.
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- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0009955
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Timing-Dependent Actions of NGF Required for Cell Differentiation.
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- PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009011
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Whole-body clearing of beetles by successive treatment with hydrogen peroxide and CUBIC reagents.
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- Entomological Science, 2020, v. 23, n. 3, p. 311, doi. 10.1111/ens.12427
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Prediction and validation of the distinct dynamics of transient and sustained ERK activation.
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- Nature Cell Biology, 2005, v. 7, n. 4, p. 365, doi. 10.1038/ncb1233
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Monitoring and mathematical modeling of mitochondrial ATP in myotubes at single-cell level reveals two distinct population with different kinetics.
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- Quantitative Biology, 2020, v. 8, n. 3, p. 228, doi. 10.1007/s40484-020-0211-8
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- Article
Selective control of up-regulated and down-regulated genes by temporal patterns and doses of insulin.
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- Science Signaling, 2016, v. 9, n. 455, p. 1, doi. 10.1126/scisignal.aaf3739
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- Article
Inositol 1,4,5-Trisphosphate-Dependent Ca<sup>2+</sup> Threshold Dynamics Detect Spike Timing in Cerebellar Purkinje Cells.
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- Journal of Neuroscience, 2005, v. 25, n. 4, p. 950, doi. 10.1523/JNEUROSCI.2727-04.2005
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Mathematical Models of the Effect of Glucagon on Glycemia in Individuals With Type 2 Diabetes Treated With Dapagliflozin.
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- Journal of the Endocrine Society, 2024, v. 8, n. 6, p. 1, doi. 10.1210/jendso/bvae067
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Model-based control of the temporal patterns of intracellular signaling in silico.
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- Biophysics & Physicobiology, 2017, v. 14, n. 1, p. 29, doi. 10.2142/biophysico.14.0_29
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Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-31547-2
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Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity.
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- Nature Materials, 2013, v. 12, n. 10, p. 932, doi. 10.1038/nmat3713
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Four features of temporal patterns characterize similarity among individuals and molecules by glucose ingestion in humans.
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- NPJ Systems Biology & Applications, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41540-022-00213-0
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System identification of signaling dependent gene expression with different time-scale data.
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- PLoS Computational Biology, 2017, v. 13, n. 12, p. 1, doi. 10.1371/journal.pcbi.1005913
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Laguerre Filter Analysis with Partial Least Square Regression Reveals a Priming Effect of ERK and CREB on c-FOS Induction.
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- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160548
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Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans.
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- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0143880
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The selective control of glycolysis, gluconeogenesis and glycogenesis by temporal insulin patterns.
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- Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1038/msb.2013.19
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