Found: 27

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  • High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53634-2
    By:
    • Rahimov, Fedik;
    • Nieminen, Pekka;
    • Kumari, Priyanka;
    • Juuri, Emma;
    • Nikopensius, Tiit;
    • Paraiso, Kitt;
    • German, Jakob;
    • Karvanen, Antti;
    • Kals, Mart;
    • Elnahas, Abdelrahman G.;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Palotie, Aarno;
    • FinnGen;
    • Heliövaara, Arja;
    • Esko, Tõnu;
    • Jukarainen, Sakari;
    • Palta, Priit;
    • Ganna, Andrea;
    • Patni, Anjali P.
    Publication type:
    Article

  • Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-32936-3
    By:
    • Rämö, Joel T.;
    • Kiiskinen, Tuomo;
    • Seist, Richard;
    • Krebs, Kristi;
    • Kanai, Masahiro;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Hämäläinen, Eija;
    • Häppölä, Paavo;
    • Havulinna, Aki S.;
    • Hautakangas, Heidi;
    • Mägi, Reedik;
    • Palta, Priit;
    • Esko, Tõnu;
    • Metspalu, Andres;
    • Pirinen, Matti;
    • Karczewski, Konrad J.;
    • Ripatti, Samuli;
    • Milani, Lili;
    • Stankovic, Konstantina M.
    Publication type:
    Article

  • Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-33626-w
    By:
    • Saarentaus, Elmo C.;
    • Karjalainen, Juha;
    • Rämö, Joel T.;
    • Kiiskinen, Tuomo;
    • Havulinna, Aki S.;
    • Mehtonen, Juha;
    • Hautakangas, Heidi;
    • Ruotsalainen, Sanni;
    • Tamlander, Max;
    • Mars, Nina;
    • Toppila-Salmi, Sanna;
    • Pirinen, Matti;
    • Kurki, Mitja;
    • Ripatti, Samuli;
    • Daly, Mark;
    • Palotie, Tuula;
    • Mäkitie, Antti;
    • Palotie, Aarno
    Publication type:
    Article

  • Efficient and accurate frailty model approach for genome-wide survival association analysis in large-scale biobanks.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32885-x
    By:
    • Dey, Rounak;
    • Zhou, Wei;
    • Kiiskinen, Tuomo;
    • Havulinna, Aki;
    • Elliott, Amanda;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Qin, Ashley;
    • FinnGen;
    • Lee, Seunggeun;
    • Palotie, Aarno;
    • Neale, Benjamin;
    • Daly, Mark;
    • Lin, Xihong
    Publication type:
    Article

  • Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy.

    Published in:
    Epilepsia (Series 4), 2015, v. 56, n. 9, p. e129, doi. 10.1111/epi.13076
    By:
    • Lal, Dennis;
    • Pernhorst, Katharina;
    • Klein, Karl Martin;
    • Reif, Philipp;
    • Tozzi, Rossana;
    • Toliat, Mohammad R.;
    • Winterer, Georg;
    • Neubauer, Bernd;
    • Nürnberg, Peter;
    • Rosenow, Felix;
    • Becker, Felicitas;
    • Lerche, Holger;
    • Kunz, Wolfram S.;
    • Kurki, Mitja I.;
    • Hoffmann, Per;
    • Becker, Albert J.;
    • Perucca, Emilio;
    • Zara, Federico;
    • Sander, Thomas;
    • Weber, Yvonne G.
    Publication type:
    Article

  • Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

    Published in:
    2019
    By:
    • Rivas, Manuel A.;
    • Avila, Brandon E.;
    • Koskela, Jukka;
    • Huang, Hailiang;
    • Stevens, Christine;
    • Pirinen, Matti;
    • Haritunians, Talin;
    • Neale, Benjamin M.;
    • Kurki, Mitja;
    • Ganna, Andrea;
    • Graham, Daniel;
    • Glaser, Benjamin;
    • Peter, Inga;
    • Atzmon, Gil;
    • Barzilai, Nir;
    • Levine, Adam P.;
    • Schiff, Elena;
    • Pontikos, Nikolas;
    • Weisburd, Ben;
    • Lek, Monkol
    Publication type:
    Correction Notice

  • Saccular Intracranial Aneurysms in Children When Both Parents Are Sporadic or Familial Carriers of Saccular Intracranial Aneurysms.

    Published in:
    Neuroepidemiology, 2019, v. 52, n. 1/2, p. 47, doi. 10.1159/000493856
    By:
    • Kurtelius, Arttu;
    • Kurki, Mitja I.;
    • von und zu Fraunberg, Mikael;
    • Väntti, Nelli;
    • Kotikoski, Satu;
    • Nurmonen, Heidi;
    • Koivisto, Timo;
    • Jääskeläinen, Juha E.;
    • Lindgren, Antti E.
    Publication type:
    Article

  • Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer.

    Published in:
    2021
    By:
    • Zhou, Wei;
    • Brumpton, Ben;
    • Kabil, Omer;
    • Gudmundsson, Julius;
    • Thorleifsson, Gudmar;
    • Weinstock, Josh;
    • Zawistowski, Matthew;
    • Nielsen, Jonas B.;
    • Chaker, Layal;
    • Medici, Marco;
    • Teumer, Alexander;
    • Naitza, Silvia;
    • Sanna, Serena;
    • Schultheiss, Ulla T.;
    • Cappola, Anne;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Oneka, Morgan;
    • Taylor, Peter;
    • Fritsche, Lars G.
    Publication type:
    Correction Notice

  • The impact of non-additive genetic associations on age-related complex diseases.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21952-4
    By:
    • Guindo-Martínez, Marta;
    • Amela, Ramon;
    • Bonàs-Guarch, Silvia;
    • Puiggròs, Montserrat;
    • Salvoro, Cecilia;
    • Miguel-Escalada, Irene;
    • Carey, Caitlin E.;
    • Cole, Joanne B.;
    • Rüeger, Sina;
    • Atkinson, Elizabeth;
    • Leong, Aaron;
    • Sanchez, Friman;
    • Ramon-Cortes, Cristian;
    • Ejarque, Jorge;
    • Palmer, Duncan S.;
    • Kurki, Mitja;
    • Aragam, Krishna;
    • Florez, Jose C.;
    • Badia, Rosa M.;
    • Mercader, Josep M.
    Publication type:
    Article

  • Diabetes is associated with familial idiopathic normal pressure hydrocephalus: a case–control comparison with family members.

    Published in:
    Fluids & Barriers of the CNS, 2020, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12987-020-00217-0
    By:
    • Räsänen, Joel;
    • Huovinen, Joel;
    • Korhonen, Ville E.;
    • Junkkari, Antti;
    • Kastinen, Sami;
    • Komulainen, Simo;
    • Oinas, Minna;
    • Avellan, Cecilia;
    • Frantzen, Janek;
    • Rinne, Jaakko;
    • Ronkainen, Antti;
    • Kauppinen, Mikko;
    • Lönnrot, Kimmo;
    • Perola, Markus;
    • Koivisto, Anne M.;
    • Remes, Anne M.;
    • Soininen, Hilkka;
    • Hiltunen, Mikko;
    • Helisalmi, Seppo;
    • Kurki, Mitja I.
    Publication type:
    Article

  • Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

    Published in:
    PLoS Genetics, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.pgen.1007329
    By:
    • Rivas, Manuel A.;
    • Avila, Brandon E.;
    • Koskela, Jukka;
    • Huang, Hailiang;
    • Stevens, Christine;
    • Pirinen, Matti;
    • Haritunians, Talin;
    • Neale, Benjamin M.;
    • Kurki, Mitja;
    • Ganna, Andrea;
    • Graham, Daniel;
    • Glaser, Benjamin;
    • Peter, Inga;
    • Atzmon, Gil;
    • Barzilai, Nir;
    • Levine, Adam P.;
    • Schiff, Elena;
    • Pontikos, Nikolas;
    • Weisburd, Ben;
    • Lek, Monkol
    Publication type:
    Article

  • Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11954-8
    By:
    • Tabassum, Rubina;
    • Rämö, Joel T.;
    • Ripatti, Pietari;
    • Koskela, Jukka T.;
    • Kurki, Mitja;
    • Karjalainen, Juha;
    • Palta, Priit;
    • Hassan, Shabbeer;
    • Nunez-Fontarnau, Javier;
    • Kiiskinen, Tuomo T. J.;
    • Söderlund, Sanni;
    • Matikainen, Niina;
    • Gerl, Mathias J.;
    • Surma, Michal A.;
    • Klose, Christian;
    • Stitziel, Nathan O.;
    • Laivuori, Hannele;
    • Havulinna, Aki S.;
    • Service, Susan K.;
    • Salomaa, Veikko
    Publication type:
    Article

  • Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08262-y
    By:
    • Kurki, Mitja I.;
    • Saarentaus, Elmo;
    • Pietiläinen, Olli;
    • Gormley, Padhraig;
    • Lal, Dennis;
    • Kerminen, Sini;
    • Torniainen-Holm, Minna;
    • Hämäläinen, Eija;
    • Rahikkala, Elisa;
    • Keski-Filppula, Riikka;
    • Rauhala, Merja;
    • Korpi-Heikkilä, Satu;
    • Komulainen-Ebrahim, Jonna;
    • Helander, Heli;
    • Vieira, Päivi;
    • Männikkö, Minna;
    • Peltonen, Markku;
    • Havulinna, Aki S.;
    • Salomaa, Veikko;
    • Pirinen, Matti
    Publication type:
    Article

  • TAFFEL: Independent Enrichment Analysis of gene sets.

    Published in:
    BMC Bioinformatics, 2011, v. 12, n. 1, p. 171, doi. 10.1186/1471-2105-12-171
    By:
    • Kurki, Mitja I.;
    • Paananen, Jussi;
    • Storvik, Markus;
    • Ylä-Herttuala, Seppo;
    • Jääskeläinen, Juha E.;
    • von und zu Fraunberg, Mikael;
    • Garry Wong;
    • Pehkonen, Petri
    Publication type:
    Article

  • Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration.

    Published in:
    JAMA Ophthalmology, 2023, v. 141, n. 2, p. 449, doi. 10.1001/jamaophthalmol.2023.0706
    By:
    • Rämö, Joel T.;
    • Abner, Erik;
    • van Dijk, Elon H. C.;
    • Wang, Xin;
    • Brinks, Joost;
    • Nikopensius, Tiit;
    • Nõukas, Margit;
    • Marjonen, Heidi;
    • Silander, Kaisa;
    • Jukarainen, Sakari;
    • Kiiskinen, Tuomo;
    • Choi, Seung Hoan;
    • Kajanne, Risto;
    • Mehtonen, Juha;
    • Palta, Priit;
    • Lubitz, Steven A.;
    • Kaarniranta, Kai;
    • Sobrin, Lucia;
    • Kurki, Mitja;
    • Yzer, Suzanne
    Publication type:
    Article

  • Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

    Published in:
    Nature Communications, 2016, v. 7, n. 9, p. 12869, doi. 10.1038/ncomms12869
    By:
    • Rivas, Manuel A.;
    • Graham, Daniel;
    • Sulem, Patrick;
    • Stevens, Christine;
    • Desch, A. Nicole;
    • Goyette, Philippe;
    • Gudbjartsson, Daniel;
    • Jonsdottir, Ingileif;
    • Thorsteinsdottir, Unnur;
    • Degenhardt, Frauke;
    • Mucha, Sören;
    • Kurki, Mitja I.;
    • Li, Dalin;
    • D'Amato, Mauro;
    • Annese, Vito;
    • Vermeire, Severine;
    • Weersma, Rinse K.;
    • Halfvarson, Jonas;
    • Paavola-Sakki, Paulina;
    • Lappalainen, Maarit
    Publication type:
    Article

  • A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

    Published in:
    Nature Communications, 2016, v. 7, n. 8, p. 12342, doi. 10.1038/ncomms12342
    By:
    • Rivas, Manuel A.;
    • Graham, Daniel;
    • Sulem, Patrick;
    • Stevens, Christine;
    • Desch, A. Nicole;
    • Goyette, Philippe;
    • Gudbjartsson, Daniel;
    • Jonsdottir, Ingileif;
    • Thorsteinsdottir, Unnur;
    • Degenhardt, Frauke;
    • Mucha, Sören;
    • Kurki, Mitja I.;
    • Li, Dalin;
    • D'Amato, Mauro;
    • Annese, Vito;
    • Vermeire, Severine;
    • Weersma, Rinse K.;
    • Halfvarson, Jonas;
    • Paavola-Sakki, Paulina;
    • Lappalainen, Maarit
    Publication type:
    Article

  • Novel patients with NHLRC2 variants expand the phenotypic spectrum of FINCA disease.

    Published in:
    Frontiers in Neuroscience, 2023, p. 01, doi. 10.3389/fnins.2023.1123327
    By:
    • Tallgren, Antti;
    • Kager, Leo;
    • O'Grady, Gina;
    • Tuominen, Hannu;
    • Körkkö, Jarmo;
    • Kuismin, Outi;
    • Feucht, Martha;
    • Wilson, Callum;
    • Behunova, Jana;
    • England, Eleina;
    • Kurki, Mitja I.;
    • Palotie, Aarno;
    • Hallman, Mikko;
    • Kaarteenaho, Riitta;
    • Laccone, Franco;
    • Boztug, Kaan;
    • Hinttala, Reetta;
    • Uusimaa, Johanna
    Publication type:
    Article

  • Increased Incidence of Aneurysmal Subarachnoid Hemorrhage on Sundays and Mondays in 1,862 Patients from Eastern Finland.

    Published in:
    Neuroepidemiology, 2011, v. 37, n. 3/4, p. 203, doi. 10.1159/000332055
    By:
    • Lindgren, Antti;
    • Huttunen, Terhi;
    • Saavalainen, Taavi;
    • Riihinen, Annamaija;
    • Kurki, Mitja I.;
    • Koivisto, Timo;
    • Ronkainen, Antti;
    • Rinne, Jaakko;
    • Hernesniemi, Jutha;
    • Jääskeläinen, Juha E.;
    • von und zu Fraunberg, Mikael
    Publication type:
    Article

  • High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004134
    By:
    • Kurki, Mitja I.;
    • Gaál, Emília Ilona;
    • Kettunen, Johannes;
    • Lappalainen, Tuuli;
    • Menelaou, Androniki;
    • Anttila, Verneri;
    • van 't Hof, Femke N. G.;
    • von und zu Fraunberg, Mikael;
    • Helisalmi, Seppo;
    • Hiltunen, Mikko;
    • Lehto, Hanna;
    • Laakso, Aki;
    • Kivisaari, Riku;
    • Koivisto, Timo;
    • Ronkainen, Antti;
    • Rinne, Jaakko;
    • Kiemeney, Lambertus A. L.;
    • Vermeulen, Sita H.;
    • Kaunisto, Mari A.;
    • Eriksson, Johan G.
    Publication type:
    Article

  • Intracranial Aneurysm Risk Locus 5q23.2 Is Associated with Elevated Systolic Blood Pressure.

    Published in:
    PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002563
    By:
    • Gaál, Emília Ilona;
    • Salo, Perttu;
    • Kristiansson, Kati;
    • Rehnström, Karola;
    • Kettunen, Johannes;
    • Sarin, Antti-Pekka;
    • ¨, Mika Niemela;
    • Jula, Antti;
    • Raitakari, Olli T.;
    • Lehtimäki, Terho;
    • Eriksson, Johan G.;
    • Widen, Elisabeth;
    • nel, Murat Gu ¨;
    • Kurki, Mitja;
    • von und zu Fraunberg, Mikael;
    • Jääskeläinen, Juha E.;
    • Hernesniemi, Juha;
    • Järvelin, Marjo-Riitta;
    • Pouta, Anneli;
    • Newton-Cheh, Christopher
    Publication type:
    Article

  • LAVAA: a lightweight association viewer across ailments.

    Published in:
    Bioinformatics Advances, 2023, v. 3, n. 1, p. 1, doi. 10.1093/bioadv/vbad018
    By:
    • Fauman, Eric B;
    • Keppo, Stella;
    • Cerioli, Nicola;
    • Vyas, Rupesh;
    • Kurki, Mitja;
    • Daly, Mark;
    • Reeve, Mary Pat
    Publication type:
    Article

  • Secondary hypertension in patients with saccular intracranial aneurysm disease: A population based study.

    Published in:
    PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0206432
    By:
    • Kotikoski, Satu;
    • Huttunen, Jukka;
    • Huttunen, Terhi J.;
    • Helin, Katariina;
    • Frösen, Juhana;
    • Koivisto, Timo;
    • Kurki, Mitja I.;
    • von und zu Fraunberg, Mikael;
    • Kunnamo, Ilkka;
    • Jääskeläinen, Juha E.;
    • Lindgren, Antti E.
    Publication type:
    Article

  • Type 2 Diabetes and Risk of Rupture of Saccular Intracranial Aneurysm in Eastern Finland.

    Published in:
    Diabetes Care, 2013, v. 36, n. 7, p. 2020, doi. 10.2337/dc12-1048
    By:
    • LINDGREN, ANTTI E.;
    • KURKI, MITJA I.;
    • RIIHINEN, ANNAMAIJA;
    • KOIVISTO, TIMO;
    • RONKAINEN, ANTTI;
    • RINNE, JAAKKO;
    • HERNESNIEMI, JUHA;
    • ERIKSSON, JOHAN G.;
    • JÄÄSKELÄINEN, JUHA E.;
    • VON UND ZU FRAUNBERG, MIKAEL
    Publication type:
    Article

  • Genome-wide association study of varicose veins identifies a protective missense variant in GJD3 enriched in the Finnish population.

    Published in:
    Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-022-04285-w
    By:
    • Helkkula, Pyry;
    • Hassan, Shabbeer;
    • Saarentaus, Elmo;
    • Vartiainen, Emilia;
    • Ruotsalainen, Sanni;
    • Leinonen, Jaakko T.;
    • FinnGen;
    • Palotie, Aarno;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Ripatti, Samuli;
    • Tukiainen, Taru
    Publication type:
    Article

  • GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17718-z
    By:
    • Zhou, Wei;
    • Brumpton, Ben;
    • Kabil, Omer;
    • Gudmundsson, Julius;
    • Thorleifsson, Gudmar;
    • Weinstock, Josh;
    • Zawistowski, Matthew;
    • Nielsen, Jonas B.;
    • Chaker, Layal;
    • Medici, Marco;
    • Teumer, Alexander;
    • Naitza, Silvia;
    • Sanna, Serena;
    • Schultheiss, Ulla T.;
    • Cappola, Anne;
    • Karjalainen, Juha;
    • Kurki, Mitja;
    • Oneka, Morgan;
    • Taylor, Peter;
    • Fritsche, Lars G.
    Publication type:
    Article

  • Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.

    Published in:
    2022
    By:
    • O'Connor, Mark J.;
    • Schroeder, Philip;
    • Huerta-Chagoya, Alicia;
    • Cortés-Sánchez, Paula;
    • Bonàs-Guarch, Silvía;
    • Guindo-Martínez, Marta;
    • Cole, Joanne B.;
    • Kaur, Varinderpal;
    • Torrents, David;
    • Veerapen, Kumar;
    • Grarup, Niels;
    • Kurki, Mitja;
    • Rundsten, Carsten F.;
    • Pedersen, Oluf;
    • Brandslund, Ivan;
    • Linneberg, Allan;
    • Hansen, Torben;
    • Leong, Aaron;
    • Florez, Jose C.;
    • Mercader, Josep M.
    Publication type:
    journal article