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A fluorescence‐based sensor for calibrated measurement of protein kinase stability in live cells.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 6, p. 1, doi. 10.1002/pro.5023
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- Publication type:
- Article
Saturation mutagenesis of a predicted ancestral Syk‐family kinase.
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- Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 10, p. 1, doi. 10.1002/pro.4411
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- Publication type:
- Article
Differences in the dynamics of the tandem‐SH2 modules of the Syk and ZAP‐70 tyrosine kinases.
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- Protein Science: A Publication of the Protein Society, 2021, v. 30, n. 12, p. 2373, doi. 10.1002/pro.4199
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- Article
A structural role for the PHP domain in E. coli DNA polymerase III.
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- BMC Structural Biology, 2013, v. 13, p. 1, doi. 10.1186/1472-6807-13-8
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- Publication type:
- Article
Analysis of the role of PCNA-DNA contacts during clamp loading.
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- BMC Structural Biology, 2010, v. 10, p. 1, doi. 10.1186/1472-6807-10-3
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- Publication type:
- Article
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).
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- BMC Structural Biology, 2009, v. 9, p. 1, doi. 10.1186/1472-6807-9-7
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- Publication type:
- Article
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
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- BMC Structural Biology, 2006, v. 6, p. 2, doi. 10.1186/1472-6807-6-2
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- Publication type:
- Article
Adaptive Capacity of a DNA Polymerase Clamp-loader ATPase Complex.
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- Molecular Biology & Evolution, 2024, v. 41, n. 3, p. 1, doi. 10.1093/molbev/msae013
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- Article
Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
- Published in:
- Nature, 2004, v. 429, n. 6993, p. 724, doi. 10.1038/nature02585
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- Publication type:
- Article
Liberal Arts Education and American Science.
- Published in:
- 2014
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- Publication type:
- Speech
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
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- EMBO Journal, 1997, v. 16, n. 20, p. 6141, doi. 10.1093/emboj/16.20.6141
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- Article
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.
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- Nature, 2012, v. 485, n. 7397, p. 260, doi. 10.1038/nature11016
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- Article
The origin of protein interactions and allostery in colocalization.
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- Nature, 2007, v. 450, n. 7172, p. 983, doi. 10.1038/nature06524
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- Publication type:
- Article
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
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- Nature, 2007, v. 450, n. 7170, p. 741, doi. 10.1038/nature05998
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- Publication type:
- Article
Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.66181
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- Publication type:
- Article
Breakage of the oligomeric CaMKII hub by the regulatory segment of the kinase.
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- eLife, 2020, p. 1, doi. 10.7554/eLife.57784
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- Publication type:
- Article
Variation in assembly stoichiometry in non‐metazoan homologs of the hub domain of Ca<sup>2+</sup>/calmodulin‐dependent protein kinase II.
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- Protein Science: A Publication of the Protein Society, 2019, v. 28, n. 6, p. 1071, doi. 10.1002/pro.3614
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- Publication type:
- Article
Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates.
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- Protein Science: A Publication of the Protein Society, 2018, v. 27, n. 5, p. 923, doi. 10.1002/pro.3397
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- Article
Structural insights into the molecular mechanism of H-NOX activation.
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- Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 4, p. 881, doi. 10.1002/pro.357
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- Article
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases.
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- Protein Science: A Publication of the Protein Society, 2005, v. 14, n. 12, p. 3135, doi. 10.1110/ps.051750905
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- Publication type:
- Article
A reinterpretation of the dimerization interface of the N-terminal Domains of STATs.
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- Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 2, p. 361, doi. 10.1110/ps.0218903
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- Publication type:
- Article
Molecular mechanisms in signal transduction at the membrane.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 659, doi. 10.1038/nsmb.1844
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- Publication type:
- Article
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 3, p. 264, doi. 10.1038/nsmb.1751
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- Publication type:
- Article
Activation of tyrosine kinases by mutation of the gatekeeper threonine.
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- Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1109, doi. 10.1038/nsmb.1486
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- Article
Erratum: Membrane-dependent signal integration by the Ras activator Son of sevenless.
- Published in:
- 2008
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- Publication type:
- Correction notice
Membrane-dependent signal integration by the Ras activator Son of sevenless.
- Published in:
- Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 452, doi. 10.1038/nsmb.1418
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- Publication type:
- Article
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex.
- Published in:
- Nature Structural & Molecular Biology, 2005, v. 12, n. 2, p. 183, doi. 10.1038/nsmb889
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- Publication type:
- Article
Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.
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- Biochemical Journal, 2015, v. 468, n. 2, p. 283, doi. 10.1042/BJ20141492
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- Publication type:
- Article
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.
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- Biochemical Journal, 2015, v. 465, n. 1, p. 149, doi. 10.1042/BJ20140793
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- Publication type:
- Article
A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.29002
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- Publication type:
- Article
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.20105
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- Publication type:
- Article
Molecular basis for multimerization in the activation of the epidermal growth factor receptor.
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- eLife, 2016, p. 1, doi. 10.7554/eLife.14107
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- Publication type:
- Article
Molecular mechanism of activation-triggered subunit exchange in Ca<sup>2+</sup>/calmodulin-dependent protein kinase II.
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- eLife, 2016, p. 1, doi. 10.7554/eLife.13405
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- Publication type:
- Article
Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.
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- eLife, 2015, p. 1, doi. 10.7554/eLife.06074
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- Publication type:
- Article
Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09358-9
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- Publication type:
- Article
Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis.
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- PLoS ONE, 2023, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0276413
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- Publication type:
- Article
Cell science and protein crystal growth research for the International Space Station.
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- Journal of Cellular Biochemistry, 2000, v. 79, n. 4, p. 662, doi. 10.1002/1097-4644(20001215)79:4<662::AID-JCB140>3.0.CO;2-4
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- Publication type:
- Article
Motors and switches: AAA+ machines within the replisome.
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- Nature Reviews Molecular Cell Biology, 2002, v. 3, n. 11, p. 826, doi. 10.1038/nrm949
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- Publication type:
- Article
The structure, regulation, and function of ZAP-70.
- Published in:
- Immunological Reviews, 2009, v. 228, n. 1, p. 41, doi. 10.1111/j.1600-065X.2008.00753.x
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- Article
Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast.
- Published in:
- Proteins, 2006, v. 62, n. 4, p. 1026, doi. 10.1002/prot.20618
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- Publication type:
- Article
Oligomerization states of the association domain and the holoenyzme of Ca<sup>2+</sup>/CaM kinase II.
- Published in:
- FEBS Journal, 2006, v. 273, n. 4, p. 682, doi. 10.1111/j.1742-4658.2005.05088.x
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- Publication type:
- Article
An SH2 domain in disguise.
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- Nature, 1999, v. 398, n. 6722, p. 22, doi. 10.1038/17916
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- Publication type:
- Article
The structural basis of the activation of Ras by Sos.
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- Nature, 1998, v. 394, n. 6691, p. 337, doi. 10.1038/28548
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- Publication type:
- Article
A highly efficient peptide substrate for EGFR activates the kinase by inducing aggregation.
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- Biochemical Journal, 2013, v. 453, n. 3, p. 337, doi. 10.1042/BJ20130537
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- Publication type:
- Article
A saturation-mutagenesis analysis of the interplay between stability and activation in Ras.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.76595
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- Publication type:
- Article
A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.73218
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- Publication type:
- Article
The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.
- Published in:
- Science Signaling, 2015, v. 8, n. 377, p. 1
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- Publication type:
- Article
Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases.
- Published in:
- Science Signaling, 2013, v. 6, n. 256, p. 1, doi. 10.1126/scisignal.2003220
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- Publication type:
- Article
Exploration of disorder in protein structures by X-ray restrained molecular dynamics.
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- Proteins, 1991, v. 10, n. 4, p. 340, doi. 10.1002/prot.340100407
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- Publication type:
- Article
Estimation of uncertainties in X-ray refinement results by use of perturbed structures.
- Published in:
- Proteins, 1987, v. 2, n. 1, p. 1, doi. 10.1002/prot.340020102
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- Publication type:
- Article