OpenURL Connection Search

Select item for more details and to access through your institution.

Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L.
Published in:
Chemical Biology & Drug Design, 2012, v. 80, n. 6, p. 971, doi. 10.1111/cbdd.12050
By:
- Basavapathruni, Aravind;
- Jin, Lei;
- Daigle, Scott R.;
- Majer, Christina R. A.;
- Therkelsen, Carly A.;
- Wigle, Tim J.;
- Kuntz, Kevin W.;
- Chesworth, Richard;
- Pollock, Roy M.;
- Scott, Margaret P.;
- Moyer, Mikel P.;
- Richon, Victoria M.;
- Copeland, Robert A.;
- Olhava, Edward J.
Publication type:
Article
Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0111840
By:
- Knutson, Sarah K.;
- Warholic, Natalie M.;
- Johnston, L. Danielle;
- Klaus, Christine R.;
- Wigle, Tim J.;
- Iwanowicz, Dorothy;
- Littlefield, Bruce A.;
- Porter-Scott, Margaret;
- Smith, Jesse J.;
- Moyer, Mikel P.;
- Copeland, Robert A.;
- Pollock, Roy M.;
- Kuntz, Kevin W.;
- Raimondi, Alejandra;
- Keilhack, Heike
Publication type:
Article
Search for Chiral Catalysts Through Ligand Diversity: Substrate-Specific Catalysts and Ligand Screening on Solid Phase.
Published in:
Angewandte Chemie International Edition, 1997, v. 36, n. 16, p. 1704, doi. 10.1002/anie.199717041
By:
- Shimizu, Ken D.;
- Cole, Bridget M.;
- Krueger, Clinton A.;
- Kuntz, Kevin W.;
- Snapper, Marc L.;
- Hoveyda, Amir H.
Publication type:
Article
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Published in:
ChemBioChem, 2021, v. 22, n. 12, p. 2107, doi. 10.1002/cbic.202100047
By:
- Wigle, Tim J.;
- Ren, Yue;
- Molina, Jennifer R.;
- Blackwell, Danielle J.;
- Schenkel, Laurie B.;
- Swinger, Kerren K.;
- Kuplast‐Barr, Kristy;
- Majer, Christina R.;
- Church, W. David;
- Lu, Alvin Z.;
- Mo, Jason;
- Abo, Ryan;
- Cheung, Anne;
- Dorsey, Bryan W.;
- Niepel, Mario;
- Perl, Nicholas R.;
- Vasbinder, Melissa M.;
- Keilhack, Heike;
- Kuntz, Kevin W.
Publication type:
Article
Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.
Published in:
2017
By:
- Kawano, Satoshi;
- Grassian, Alexandra R.;
- Tsuda, Masumi;
- Knutson, Sarah K.;
- Warholic, Natalie M.;
- Kuznetsov, Galina;
- Xu, Shanqin;
- Xiao, Yonghong;
- Pollock, Roy M.;
- Smith, Jesse J.;
- Kuntz, Kevin W.;
- Ribich, Scott;
- Minoshima, Yukinori;
- Matsui, Junji;
- Copeland, Robert A.;
- Tanaka, Shinya;
- Keilhack, Heike
Publication type:
Correction Notice
A687V EZH2 is a gain-of-function mutation found in lymphoma patients
Published in:
FEBS Letters, 2012, v. 586, n. 19, p. 3448, doi. 10.1016/j.febslet.2012.07.066
By:
- Majer, Christina R.;
- Jin, Lei;
- Scott, Margaret Porter;
- Knutson, Sarah K.;
- Kuntz, Kevin W.;
- Keilhack, Heike;
- Smith, Jesse J.;
- Moyer, Mikel P.;
- Richon, Victoria M.;
- Copeland, Robert A.;
- Wigle, Tim J.
Publication type:
Article
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states
Published in:
FEBS Letters, 2011, v. 585, n. 19, p. 3011, doi. 10.1016/j.febslet.2011.08.018
By:
- Wigle, Tim J.;
- Knutson, Sarah K.;
- Jin, Lei;
- Kuntz, Kevin W.;
- Pollock, Roy M.;
- Richon, Victoria M.;
- Copeland, Robert A.;
- Scott, Margaret Porter
Publication type:
Article
Identification of a peptide inhibitor for the histone methyltransferase WHSC1.
Published in:
PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197082
By:
- Morrison, Michael J.;
- Boriack-Sjodin, P. Ann;
- Swinger, Kerren K.;
- Wigle, Tim J.;
- Sadalge, Dipti;
- Kuntz, Kevin W.;
- Scott, Margaret Porter;
- Janzen, William P.;
- Chesworth, Richard;
- Duncan, Kenneth W.;
- Harvey, Darren M.;
- Lampe, John W.;
- Mitchell, Lorna H.;
- Copeland, Robert A.
Publication type:
Article

Found: 8