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Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47031-y
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- Publication type:
- Article
Functional analysis of structural variants in single cells using Strand-seq.
- Published in:
- Nature Biotechnology, 2023, v. 41, n. 6, p. 832, doi. 10.1038/s41587-022-01551-4
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- Publication type:
- Article
Newborn screening for abnormal haemoglobins in Jamaica: Practical issues in an island programme.
- Published in:
- Journal of Medical Screening, 2022, v. 29, n. 4, p. 219, doi. 10.1177/09691413221111209
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- Publication type:
- Article
Investigation of Iron Deficiency and Iron Overload.
- Published in:
- Deutsches Ärzteblatt International, 2021, v. 118, n. 49, p. 847, doi. 10.3238/arztebl.m2021.0290
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- Publication type:
- Article
Benefits of a Disease Management Program for Sickle Cell Disease in Germany 2011–2019: The Increased Use of Hydroxyurea Correlates with a Reduced Frequency of Acute Chest Syndrome.
- Published in:
- Journal of Clinical Medicine, 2021, v. 10, n. 19, p. 4543, doi. 10.3390/jcm10194543
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- Publication type:
- Article
Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
- Published in:
- Nucleic Acids Research, 2021, v. 49, n. 13, p. 7665, doi. 10.1093/nar/gkab532
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- Publication type:
- Article
Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient‐derived osteosarcoma cells and synergizes with cisplatin and talazoparib.
- Published in:
- International Journal of Cancer, 2020, v. 147, n. 4, p. 1059, doi. 10.1002/ijc.32814
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- Publication type:
- Article
Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 9, p. 4725, doi. 10.1093/nar/gkaa256
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- Publication type:
- Article
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing.
- Published in:
- Nature Biotechnology, 2020, v. 38, n. 3, p. 343, doi. 10.1038/s41587-019-0366-x
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- Publication type:
- Article
PTEN abnormalities predict poor outcome in children with T‐cell acute lymphoblastic leukemia treated according to ALL IC‐BFM protocols.
- Published in:
- American Journal of Hematology, 2019, v. 94, n. 4, p. E93, doi. 10.1002/ajh.25396
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- Publication type:
- Article
Expression of CD56 defines a distinct subgroup in childhood T‐ALL with inferior outcome. Results of the ALL‐BFM 2000 trial.
- Published in:
- British Journal of Haematology, 2018, v. 183, n. 1, p. 96, doi. 10.1111/bjh.15503
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- Publication type:
- Article
MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB.
- Published in:
- 2018
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- Publication type:
- journal article
Dual function of UPF3B in early and late translation termination.
- Published in:
- EMBO Journal, 2017, v. 36, n. 20, p. 2968, doi. 10.15252/embj.201797079
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- Publication type:
- Article
The epidemiology of sickle cell disease in Germany following recent large-scale immigration.
- Published in:
- 2017
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- Publication type:
- journal article
Insights into the design and interpretation of iCLIP experiments.
- Published in:
- Genome Biology, 2017, v. 18, p. 1, doi. 10.1186/s13059-016-1130-x
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- Publication type:
- Article
Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.
- Published in:
- Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326
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- Publication type:
- Article
Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG- MDS study group.
- Published in:
- British Journal of Haematology, 2016, v. 172, n. 6, p. 930, doi. 10.1111/bjh.13915
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- Publication type:
- Article
Significant prevalence of sickle cell disease in Southwest Germany: results from a birth cohort study indicate the necessity for newborn screening.
- Published in:
- 2016
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- Publication type:
- journal article
HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.
- Published in:
- Biomolecules (2218-273X), 2015, v. 5, n. 4, p. 2808, doi. 10.3390/biom5042808
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- Publication type:
- Article
A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 15, p. 7600, doi. 10.1093/nar/gkv668
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- Publication type:
- Article
Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP.
- Published in:
- Nature Communications, 2015, v. 6, n. 8, p. 7921, doi. 10.1038/ncomms8921
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- Publication type:
- Article
Treatment tolerance of particle therapy in pediatric patients.
- Published in:
- Acta Oncologica, 2015, v. 54, n. 7, p. 1049, doi. 10.3109/0284186X.2014.998273
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- Publication type:
- Article
Five years of experience with biochemical cystic fibrosis newborn screening based on IRT/PAP in Germany.
- Published in:
- Pediatric Pulmonology, 2015, v. 50, n. 7, p. 655, doi. 10.1002/ppul.23190
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- Publication type:
- Article
Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy.
- Published in:
- Radiation Oncology, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13014-015-0455-z
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- Publication type:
- Article
Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy.
- Published in:
- Radiation Oncology, 2015, v. 10, n. 1, p. 146, doi. 10.1186/s13014-015-0455-z
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- Publication type:
- Article
Establishment of a patient-derived orthotopic osteosarcoma mouse model.
- Published in:
- Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0497-x
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- Publication type:
- Article
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
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- Publication type:
- Article
5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.
- Published in:
- EMBO Molecular Medicine, 2014, v. 6, n. 12, p. 1593, doi. 10.15252/emmm.201404461
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- Publication type:
- Article
Childhood acute lymphoblastic leukemia in the Middle East and neighboring countries: A prospective multi-institutional international collaborative study (CALLME1) by the Middle East Childhood Cancer Alliance (MECCA)
- Published in:
- 2014
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- Publication type:
- Journal Article
Childhood acute lymphoblastic leukemia in the Middle East and neighboring countries: A prospective multi-institutional international collaborative study (CALLME1) by the Middle East Childhood Cancer Alliance (MECCA).
- Published in:
- Pediatric Blood & Cancer, 2014, v. 61, n. 8, p. 1403, doi. 10.1002/pbc.25031
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- Publication type:
- Article
mRNA 3′end processing: A tale of the tail reaches the clinic.
- Published in:
- EMBO Molecular Medicine, 2014, v. 6, n. 1, p. 16, doi. 10.1002/emmm.201303300
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- Publication type:
- Article
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 12, p. 6018, doi. 10.1093/nar/gkt346
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- Publication type:
- Article
Nonsense-Mediated mRNA Decay and Loss-of-Function of the Protein Underlie the X-Linked Epilepsy Associated with the W356× Mutation in Synapsin I.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067724
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- Publication type:
- Article
Nestin Expression Identifies Ependymoma Patients with Poor Outcome.
- Published in:
- Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x
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- Publication type:
- Article
A 15q24 microdeletion in transient myeloproliferative disease ( TMD) and acute megakaryoblastic leukaemia ( AMKL) implicates PML and SUMO3 in the leukaemogenesis of TMD/ AMKL.
- Published in:
- British Journal of Haematology, 2012, v. 157, n. 2, p. 180, doi. 10.1111/j.1365-2141.2012.09028.x
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- Publication type:
- Article
Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT): establishment of workflow and initial clinical data.
- Published in:
- Radiation Oncology, 2012, v. 7, n. 1, p. 170, doi. 10.1186/1748-717X-7-170
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- Publication type:
- Article
Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
- Published in:
- International Journal of Cancer, 2010, v. 127, n. 5, p. 1230, doi. 10.1002/ijc.25168
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- Publication type:
- Article
Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.
- Published in:
- Acta Neuropathologica, 2010, v. 120, n. 2, p. 253, doi. 10.1007/s00401-010-0688-8
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- Publication type:
- Article
Hemoglobinopathies Are on the Increase.
- Published in:
- 2010
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- Publication type:
- Editorial
Non-randomized therapy trial to determine thesafety and efficacy of heavy ion radiotherapy inpatients with non-resectable osteosarcoma.
- Published in:
- BMC Cancer, 2010, v. 10, p. 96, doi. 10.1186/1471-2407-10-96
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- Publication type:
- Article
Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept.
- Published in:
- BMC Cancer, 2010, v. 10, p. 450, doi. 10.1186/1471-2407-10-450
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- Publication type:
- Article
Downregulation of Notch signaling by γ-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines.
- Published in:
- Annals of Hematology, 2009, v. 88, n. 7, p. 613, doi. 10.1007/s00277-008-0646-x
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- Publication type:
- Article
The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay.
- Published in:
- PLoS Biology, 2009, v. 7, n. 5, p. 1, doi. 10.1371/journal.pbio.1000120
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- Publication type:
- Article
Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 8, p. 1891, doi. 10.1002/ijc.23295
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- Publication type:
- Article
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.
- Published in:
- EMBO Journal, 2008, v. 27, n. 5, p. 736, doi. 10.1038/emboj.2008.17
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- Publication type:
- Article
Treatment of neuroblastoma-related opsoclonus-myoclonus-ataxia syndrome with high-dose dexamethasone pulses.
- Published in:
- Pediatric Blood & Cancer, 2008, v. 50, n. 3, p. 683, doi. 10.1002/pbc.21107
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- Publication type:
- Article
3′ end mRNA processing: molecular mechanisms and implications for health and disease.
- Published in:
- EMBO Journal, 2008, v. 27, n. 3, p. 482, doi. 10.1038/sj.emboj.7601932
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- Publication type:
- Article
Long-term remission of children with relapsed and secondary anaplastic large cell non-Hodgkin lymphoma (ALCL) following treatment with pulsed dexamethasone and low dose etoposide.
- Published in:
- Pediatric Blood & Cancer, 2008, v. 50, n. 1, p. 126, doi. 10.1002/pbc.20838
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- Publication type:
- Article
The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells.
- Published in:
- European Journal of Human Genetics, 2007, v. 15, n. 11, p. 1156, doi. 10.1038/sj.ejhg.5201889
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- Publication type:
- Article
The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway.
- Published in:
- Nucleic Acids Research, 2007, v. 35, n. 13, p. 4542, doi. 10.1093/nar/gkm461
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- Publication type:
- Article