Works by Kulbe, Hagen

Results: 28

Ovarian tumours of different histologic type and clinical stage induce similar changes in lipid metabolism.

Published in:

2018

By:

Niemi, Riikka Johanna;
Braicu, Elena Ioana;
Kulbe, Hagen;
Koistinen, Kaisa Maria;
Sehouli, Jalid;
Puistola, Ulla;
Mäenpää, Johanna Unelma;
Hilvo, Mika

Publication type:

journal article

Characterisation of tumour microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact (an OCTIPS Consortium study).

Published in:

2018

By:

Ruscito, Ilary;
Cacsire Castillo-Tong, Dan;
Vergote, Ignace;
Ignat, Iulia;
Stanske, Mandy;
Vanderstichele, Adriaan;
Glajzer, Jacek;
Kulbe, Hagen;
Trillsch, Fabian;
Mustea, Alexander;
Kreuzinger, Caroline;
Benedetti Panici, Pierluigi;
Gourley, Charlie;
Gabra, Hani;
Nuti, Marianna;
Taube, Eliane T.;
Kessler, Mirjana;
Sehouli, Jalid;
Darb-Esfahani, Silvia;
Braicu, Elena Ioana

Publication type:

journal article

Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer.

Published in:

Cells (2073-4409), 2019, v. 8, n. 7, p. 713, doi. 10.3390/cells8070713

By:

Kulbe, Hagen;
Otto, Raik;
Darb-Esfahani, Silvia;
Lammert, Hedwig;
Abobaker, Salem;
Welsch, Gabriele;
Chekerov, Radoslav;
Schäfer, Reinhold;
Dragun, Duska;
Hummel, Michael;
Leser, Ulf;
Sehouli, Jalid;
Braicu, Elena Ioana

Publication type:

Article

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

Published in:

2017

By:

Berlato, Chiara;
Khan, Moddasar N.;
Schioppa, Tiziana;
Thompson, Richard;
Maniati, Eleni;
Montfort, Anne;
Jangani, Maryam;
Canosa, Monica;
Kulbe, Hagen;
Hagemann, Urs B.;
Duncan, Alexander R.;
Fletcher, Laura;
Wilkinson, Robert W.;
Powles, Thomas;
Quezada, Sergio A.;
Balkwill, Frances R.

Publication type:

journal article

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.

Published in:

2009

By:

Charles, Kellie A;
Kulbe, Hagen;
Soper, Robin;
Escorcio-Correia, Monica;
Lawrence, Toby;
Schultheis, Anne;
Chakravarty, Probir;
Thompson, Richard G;
Kollias, George;
Smyth, John F;
Balkwill, Frances R;
Hagemann, Thorsten

Publication type:

journal article

The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans.

Published in:

Journal of Clinical Investigation, 2009, v. 119, n. 10, p. 3011, doi. 10.1172/JCI39065

By:

Charles, Kellie A.;
Kulbe, Hagen;
Soper, Robin;
Escorcio-Correia, Monica;
Lawrence, Toby;
Schuitheis, Anne;
Chakravarty, Probir;
Thompson, Richard G.;
Kollias, George;
Smyth, John F.;
Balkwill, Frances A.;
Hagemann, Thorsten

Publication type:

Article

Stable expansion of high‐grade serous ovarian cancer organoids requires a low‐Wnt environment.

Published in:

EMBO Journal, 2020, v. 39, n. 6, p. 1, doi. 10.15252/embj.2019104013

By:

Hoffmann, Karen;
Berger, Hilmar;
Kulbe, Hagen;
Thillainadarasan, Sukanija;
Mollenkopf, Hans‐Joachim;
Zemojtel, Tomasz;
Taube, Eliane;
Darb‐Esfahani, Silvia;
Mangler, Mandy;
Sehouli, Jalid;
Chekerov, Radoslav;
Braicu, Elena I;
Meyer, Thomas F;
Kessler, Mirjana

Publication type:

Article

Prognostic value of regulatory T cells and T helper 17 cells in high grade serous ovarian carcinoma.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 6, p. 2523, doi. 10.1007/s00432-022-04101-2

By:

Marchenko, Sofya;
Piwonski, Iris;
Hoffmann, Inga;
Sinn, Bruno Valentin;
Kunze, Catarina Alisa;
Monjé, Nanna;
Pohl, Jonathan;
Kulbe, Hagen;
Schmitt, Wolfgang Daniel;
Darb-Esfahani, Sylvia;
Braicu, Elena Ioana;
von Brünneck, Ann-Christin;
Sehouli, Jalid;
Denkert, Carsten;
Horst, David;
Jöhrens, Korinna;
Taube, Eliane Tabea

Publication type:

Article

Vascular endothelial growth factor receptor 2 (VEGFR2) correlates with long-term survival in patients with advanced high-grade serous ovarian cancer (HGSOC): a study from the Tumor Bank Ovarian Cancer (TOC) Consortium.

Published in:

Journal of Cancer Research & Clinical Oncology, 2019, v. 145, n. 4, p. 1063, doi. 10.1007/s00432-019-02877-4

By:

Guan, Jun;
Darb-Esfahani, Silvia;
Richter, Rolf;
Taube, Eliane T.;
Ruscito, Ilary;
Mahner, Sven;
Woelber, Linn;
Prieske, Katharina;
Concin, Nicole;
Vergote, Ignace;
Van Nieuwenhuysen, Els;
Achimas-Cadariu, Patriciu;
Glajzer, Joanna;
Woopen, Hannah;
Stanske, Mandy;
Kulbe, Hagen;
Denkert, Carsten;
Sehouli, Jalid;
Braicu, Elena Ioana

Publication type:

Article

Discovery of Prognostic Markers for Early-Stage High-Grade Serous Ovarian Cancer by Maldi-Imaging.

Published in:

Cancers, 2020, v. 12, n. 8, p. 2000, doi. 10.3390/cancers12082000

By:

Kulbe, Hagen;
Klein, Oliver;
Wu, Zhiyang;
Taube, Eliane T.;
Kassuhn, Wanja;
Horst, David;
Darb-Esfahani, Silvia;
Jank, Paul;
Abobaker, Salem;
Ringel, Frauke;
du Bois, Andreas;
Heitz, Florian;
Sehouli, Jalid;
Braicu, Elena I.

Publication type:

Article

Long-term tumor growth suppression in mice immunized with naked DNA of the human tumor antigen mucin (MUC1).

Published in:

Cancer Immunology, Immunotherapy, 2001, v. 50, n. 7, p. 356, doi. 10.1007/s002620100212

By:

Johnen, Heiko;
Kulbe, Hagen;
Pecher, Gabriele

Publication type:

Article

Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells.

Published in:

Molecular Therapy, 2013, v. 21, n. 11, p. 2074, doi. 10.1038/mt.2013.195

By:

Whilding, Lynsey M;
Archibald, Kyra M;
Kulbe, Hagen;
Balkwill, Frances R;
Öberg, Daniel;
McNeish, Iain A

Publication type:

Article

Inhibition of the Inflammatory Cytokine TNF-α Increases Adenovirus Activity in Ovarian Cancer via Modulation of cIAP1/2 Expression.

Published in:

Molecular Therapy, 2011, v. 19, n. 3, p. 490, doi. 10.1038/mt.2010.247

By:

Salako, Michael A.;
Kulbe, Hagen;
Ingemarsdotter, Carin K.;
Pirlo, Katrina J.;
Williams, Sarah L.;
Lockley, Michelle;
Balkwill, Frances R.;
McNeish, Iain A.

Publication type:

Article

AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.

Published in:

British Journal of Cancer, 2024, v. 130, n. 8, p. 1249, doi. 10.1038/s41416-023-02550-1

By:

Monjé, Nanna;
Dragomir, Mihnea P.;
Sinn, Bruno V.;
Hoffmann, Inga;
Makhmut, Anuar;
Simon, Tincy;
Kunze, Catarina A.;
Ihlow, Jana;
Schmitt, Wolfgang D.;
Pohl, Jonathan;
Piwonski, Iris;
Marchenko, Sofya;
Keunecke, Carlotta;
Calina, Teodor G.;
Tiso, Francesca;
Kulbe, Hagen;
Kreuzinger, Caroline;
Cacsire Castillo-Tong, Dan;
Sehouli, Jalid;
Braicu, Elena I.

Publication type:

Article

Pre-Operative Malnutrition in Patients with Ovarian Cancer: What Are the Clinical Implications? Results of a Prospective Study.

Published in:

Cancers, 2024, v. 16, n. 3, p. 622, doi. 10.3390/cancers16030622

By:

Nasser, Sara;
Bilir, Esra;
Derin, Xezal;
Richter, Rolf;
Grabowski, Jacek P.;
Ali, Paulina;
Kulbe, Hagen;
Chekerov, Radoslav;
Braicu, Elena;
Sehouli, Jalid

Publication type:

Article

In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients.

Published in:

Cancers, 2023, v. 15, n. 12, p. 3155, doi. 10.3390/cancers15123155

By:

Kassuhn, Wanja;
Cutillas, Pedro R.;
Kessler, Mirjana;
Sehouli, Jalid;
Braicu, Elena I.;
Blüthgen, Nils;
Kulbe, Hagen

Publication type:

Article

Low Expression of RGS2 Promotes Poor Prognosis in High-Grade Serous Ovarian Cancer.

Published in:

Cancers, 2022, v. 14, n. 19, p. 4620, doi. 10.3390/cancers14194620

By:

Ihlow, Jana;
Monjé, Nanna;
Hoffmann, Inga;
Bischoff, Philip;
Sinn, Bruno Valentin;
Schmitt, Wolfgang Daniel;
Kunze, Catarina Alisa;
Darb-Esfahani, Sylvia;
Kulbe, Hagen;
Braicu, Elena Ioana;
Sehouli, Jalid;
Denkert, Carsten;
Horst, David;
Taube, Eliane Tabea

Publication type:

Article

Cell-Free-DNA-Based Copy Number Index Score in Epithelial Ovarian Cancer—Impact for Diagnosis and Treatment Monitoring.

Published in:

Cancers, 2022, v. 14, n. 1, p. 168, doi. 10.3390/cancers14010168

By:

Braicu, Elena Ioana;
du Bois, Andreas;
Sehouli, Jalid;
Beck, Julia;
Prader, Sonia;
Kulbe, Hagen;
Eiben, Bernd;
Harter, Philipp;
Traut, Alexander;
Pietzner, Klaus;
Glaubitz, Ralf;
Ataseven, Beyhan;
Chekerov, Radoslav;
Keck, Christoph;
Winkler, Thomas;
Heikaus, Sebastian;
Gellendin, Peggy;
Schütz, Ekkehard;
Heitz, Florian

Publication type:

Article

A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.

Published in:

Cancers, 2021, v. 13, n. 8, p. 1764, doi. 10.3390/cancers13081764

By:

Salminen, Liina;
Braicu, Elena Ioana;
Lääperi, Mitja;
Jylhä, Antti;
Oksa, Sinikka;
Hietanen, Sakari;
Sehouli, Jalid;
Kulbe, Hagen;
Bois, Andreas du;
Mahner, Sven;
Harter, Philipp;
Carpén, Olli;
Huhtinen, Kaisa;
Hynninen, Johanna;
Hilvo, Mika;
Bianchi, Fabrizio

Publication type:

Article

Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging.

Published in:

Cancers, 2021, v. 13, n. 7, p. 1512, doi. 10.3390/cancers13071512

By:

Kassuhn, Wanja;
Klein, Oliver;
Darb-Esfahani, Silvia;
Lammert, Hedwig;
Handzik, Sylwia;
Taube, Eliane T.;
Schmitt, Wolfgang D.;
Keunecke, Carlotta;
Horst, David;
Dreher, Felix;
George, Joshy;
Bowtell, David D.;
Dorigo, Oliver;
Hummel, Michael;
Sehouli, Jalid;
Blüthgen, Nils;
Kulbe, Hagen;
Braicu, Elena I.;
Pagni, Fabio;
Stefania, Galimberti

Publication type:

Article

Morphology and tumour‐infiltrating lymphocytes in high‐stage, high‐grade serous ovarian carcinoma correlated with long‐term survival.

Published in:

Histopathology, 2018, v. 73, n. 6, p. 1002, doi. 10.1111/his.13711

By:

Darb‐Esfahani, Silvia;
Kolaschinski, Ivonne;
Trillsch, Fabian;
Mahner, Sven;
Concin, Nicole;
Vergote, Ignace;
Van Nieuwenhuysen, Els;
Achimas‐Cadariu, Patriciu;
Glajzer, Joanna;
Woopen, Hannah;
Wienert, Stefan;
Taube, Eliane T;
Stanske, Mandy;
Kulbe, Hagen;
Denkert, Carsten;
Sehouli, Jalid;
Braicu, Elena I

Publication type:

Article

ASO Visual Abstract: Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy—Innovative Models Prolong Survival (OCTIPS) Consortium

Published in:

2023

By:

Glajzer, Jacek;
Castillo-Tong, Dan Cacsire;
Richter, Rolf;
Vergote, Ignace;
Kulbe, Hagen;
Vanderstichele, Adriaan;
Ruscito, Ilary;
Trillsch, Fabian;
Mustea, Alexander;
Kreuzinger, Caroline;
Gourley, Charlie;
Gabra, Hani;
Taube, Eliane T.;
Dorigo, Oliver;
Horst, David;
Keunecke, Carlotta;
Baum, Joanna;
Angelotti, Timothy;
Sehouli, Jalid;
Braicu, Elena Ioana

Publication type:

Abstract

Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium

Published in:

Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2023, v. 30, n. 1, p. 35, doi. 10.1245/s10434-022-12459-3

By:

Glajzer, Jacek;
Castillo-Tong, Dan Cacsire;
Richter, Rolf;
Vergote, Ignace;
Kulbe, Hagen;
Vanderstichele, Adriaan;
Ruscito, Ilary;
Trillsch, Fabian;
Mustea, Alexander;
Kreuzinger, Caroline;
Gourley, Charlie;
Gabra, Hani;
Taube, Eliane T.;
Dorigo, Oliver;
Horst, David;
Keunecke, Carlotta;
Baum, Joanna;
Angelotti, Timothy;
Sehouli, Jalid;
Braicu, Elena Ioana

Publication type:

Article

MALDI‐Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods.

Published in:

Proteomics - Clinical Applications, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1002/prca.201700181

By:

Klein, Oliver;
Kanter, Frederic;
Kulbe, Hagen;
Jank, Paul;
Denkert, Carsten;
Nebrich, Grit;
Schmitt, Wolfgang D.;
Wu, Zhiyang;
Kunze, Catarina A.;
Sehouli, Jalid;
Darb‐Esfahani, Silvia;
Braicu, Ioana;
Lellmann, Jan;
Thiele, Herbert;
Taube, Eliane T.

Publication type:

Article

Front Cover: MALDI‐Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods.

Published in:

Proteomics - Clinical Applications, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1002/prca.201970011

By:

Klein, Oliver;
Kanter, Frederic;
Kulbe, Hagen;
Jank, Paul;
Denkert, Carsten;
Nebrich, Grit;
Schmitt, Wolfgang D.;
Wu, Zhiyang;
Kunze, Catarina A.;
Sehouli, Jalid;
Darb‐Esfahani, Silvia;
Braicu, Ioana;
Lellmann, Jan;
Thiele, Herbert;
Taube, Eliane T.

Publication type:

Article

High EVI1 and PARP1 expression as favourable prognostic markers in high-grade serous ovarian carcinoma.

Published in:

Journal of Ovarian Research, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13048-023-01239-6

By:

Jank, Paul;
Leichsenring, Jonas;
Kolb, Svenja;
Hoffmann, Inga;
Bischoff, Philip;
Kunze, Catarina Alisa;
Dragomir, Mihnea P.;
Gleitsmann, Moritz;
Jesinghaus, Moritz;
Schmitt, Wolfgang D.;
Kulbe, Hagen;
Sers, Christine;
Stenzinger, Albrecht;
Sehouli, Jalid;
Braicu, Ioana Elena;
Westhoff, Christina;
Horst, David;
Denkert, Carsten;
Gröschel, Stefan;
Taube, Eliane T.

Publication type:

Article

Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts.

Published in:

Journal of Pathology, 2014, v. 232, n. 1, p. 43, doi. 10.1002/path.4258

By:

Lau, Tat‐San;
Chung, Tony Kwok‐Hung;
Cheung, Tak‐Hong;
Chan, Loucia Kit‐Ying;
Cheung, Leonard Wing‐Hong;
Yim, So‐Fan;
Siu, Nelson Shing‐Shun;
Lo, Kwok‐Wai;
Yu, May Mei‐Yung;
Kulbe, Hagen;
Balkwill, Frances R;
Kwong, Joseph

Publication type:

Article

The peritoneal tumour microenvironment of high-grade serous ovarian cancer.

Published in:

Journal of Pathology, 2012, v. 227, n. 2, p. 136, doi. 10.1002/path.4002

By:

Leinster, D Andrew;
Kulbe, Hagen;
Everitt, Gemma;
Thompson, Richard;
Perretti, Mauro;
Gavins, Felicity N. E;
Cooper, Dianne;
Gould, David;
Ennis, Darren P;
Lockley, Michelle;
McNeish, Iain A;
Nourshargh, Sussan;
Balkwill, Frances R

Publication type:

Article