Works by Kulanthaivel, Palaniappan

Results: 9

Optimising the combination dosing strategy of abemaciclib and vemurafenib in BRAF-mutated melanoma xenograft tumours.

Published in:

2016

By:

Tate, Sonya C;
Burke, Teresa F;
Hartman, Daisy;
Kulanthaivel, Palaniappan;
Beckmann, Richard P;
Cronier, Damien M

Publication type:

journal article

Predicting Clinical Effects of CYP3A4 Modulators on Abemaciclib and Active Metabolites Exposure Using Physiologically Based Pharmacokinetic Modeling.

Published in:

Journal of Clinical Pharmacology, 2020, v. 60, n. 7, p. 915, doi. 10.1002/jcph.1584

By:

Posada, Maria M.;
Morse, Bridget L.;
Turner, P. Kellie;
Kulanthaivel, Palaniappan;
Hall, Stephen D.;
Dickinson, Gemma L.

Publication type:

Article

Abemaciclib does not increase the corrected QT interval in healthy participants.

Published in:

CTS: Clinical & Translational Science, 2023, v. 16, n. 9, p. 1617, doi. 10.1111/cts.13573

By:

Chappell, Jill C.;
Chiang, Alan Y.;
Royalty, Jane;
Coleman, Hugh;
Kulanthaivel, Palaniappan;
Turner, P. Kellie

Publication type:

Article

A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients.

Published in:

2018

By:

Tate, Sonya C.;
Sykes, Amanda K.;
Kulanthaivel, Palaniappan;
Chan, Edward M.;
Turner, P. Kellie;
Cronier, Damien M.

Publication type:

journal article

Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 5, p. 1187, doi. 10.1002/cpt.1296

By:

Chappell, Jill C.;
Turner, P. Kellie;
Pak, Y. Anne;
Bacon, James;
Chiang, Alan Y.;
Hall, Stephen D.;
Kulanthaivel, Palaniappan;
Royalty, Jane;
Bonventre, Joseph V.

Publication type:

Article

A Panel of Cytochrome P450 BM3 Variants to Produce Drug Metabolites and Diversify Lead Compounds.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 43, p. 11723, doi. 10.1002/chem.200900643

By:

Sawayama, Andrew M.;
Chen, Michael M. Y.;
Kulanthaivel, Palaniappan;
Kuo, Ming-Shang;
Hemmerle, Horst;
Arnold, Frances H.

Publication type:

Article

Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 4, p. 629, doi. 10.1007/s10637-017-0532-2

By:

Goldman, Jonathan W.;
Rosen, Lee S.;
Tolcher, Anthony W.;
Papadopoulos, Kyriakos;
Beeram, Muralidhar;
Shi, Peipei;
Pitou, Celine;
Bell, Robert;
Kulanthaivel, Palaniappan;
Zhang, Xuekui;
Fink, Aaron;
Chan, Edward M.;
Shahir, Ashwin;
Farrington, Daphne;
Patnaik, Amita

Publication type:

Article

A method for the synthesis of 2-amino-4-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid-[<sup>3</sup>H<sub>2</sub>].

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2004, v. 47, n. 9, p. 571, doi. 10.1002/jlcr.843

By:

Kuo, Fengjiun;
Kulanthaivel, Palaniappan;
Rener, Gregory A.;
Yi, Ping;
Wheeler, William J.

Publication type:

Article

Utilizing F NMR to investigate drug disposition early in drug discovery.

Published in:

Xenobiotica, 2015, v. 45, n. 12, p. 1081, doi. 10.3109/00498254.2015.1040866

By:

Hu, Haitao;
Huang, Naijia;
Yi, Ping;
Hui, Yu-Hua;
Dally, Robert D.;
Ehlhardt, William J.;
Kulanthaivel, Palaniappan

Publication type:

Article