Works by Kuhle, Jens

Results: 237
    1

    AI-assisted identification of disability patterns within identical EDSS grades.

    Published in:
    Multiple Sclerosis Journal, 2025, v. 31, n. 6, p. 677, doi. 10.1177/13524585251327300
    By:
    • Greselin, Martina;
    • Lu, Po-Jui;
    • Mroczek, Magdalena;
    • Cerdá-Fuertes, Nuria;
    • Demirtzoglou, Anastasios;
    • Papadopoulou, Athina;
    • Kuhle, Jens;
    • Leppert, David;
    • Arnould, Sophie;
    • Aoun, Manar;
    • Kappos, Ludwig;
    • Granziera, Cristina;
    • D'Souza, Marcus
    Publication type:
    Article
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    Comparative effectiveness of dimethyl fumarate versus non-specific immunosuppressants: Real-world evidence from MSBase.

    Published in:
    Multiple Sclerosis Journal - Experimental, Translational & Clinical, 2024, v. 10, n. 2, p. 1, doi. 10.1177/20552173241247182
    By:
    • Spelman, Tim;
    • Eichau, Sara;
    • Alroughani, Raed;
    • Ozakbas, Serkan;
    • Khoury, Samia J.;
    • Patti, Francesco;
    • Havrdova, Eva Kubala;
    • Boz, Cavit;
    • Terzi, Murat;
    • Kuhle, Jens;
    • Grammond, Pierre;
    • Lechner-Scott, Jeanette;
    • Gray, Orla;
    • Amato, Maria Pia;
    • Laureys, Guy;
    • Shaygannejad, Vahid;
    • Hyde, Robert;
    • Haijue Wang;
    • Bozin, Ivan;
    • Belviso, Nicholas
    Publication type:
    Article
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    Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer's disease.

    Published in:
    Brain Communications, 2024, v. 6, n. 5, p. 1, doi. 10.1093/braincomms/fcae357
    By:
    • Vermunt, Lisa;
    • Sutphen, Courtney L;
    • Dicks, Ellen;
    • Leeuw, Diederick M de;
    • Allegri, Ricardo F;
    • Berman, Sarah B;
    • Cash, David M;
    • Chhatwal, Jasmeer P;
    • Cruchaga, Carlos;
    • Day, Gregory S;
    • Ewers, Michael;
    • Farlow, Martin R;
    • Fox, Nick C;
    • Ghetti, Bernardino;
    • Graff-Radford, Neill R;
    • Hassenstab, Jason;
    • Jucker, Mathias;
    • Karch, Celeste M;
    • Kuhle, Jens;
    • Laske, Christoph
    Publication type:
    Article
    4

    The role of neurofilament light in genetic frontotemporal lobar degeneration.

    Published in:
    Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcac310
    By:
    • Zetterberg, Henrik;
    • Teunissen, Charlotte;
    • van Swieten, John;
    • Kuhle, Jens;
    • Boxer, Adam;
    • Rohrer, Jonathan D.;
    • Mitic, Laura;
    • Nicholson, Alexandra M.;
    • Pearlman, Rodney;
    • McCaughey, Stella Mayo;
    • Tatton, Nadine
    Publication type:
    Article
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    Blood-Based Biomarkers for Identifying Disease Activity in AQP4-IgG–Positive Neuromyelitis Optica Spectrum Disorder.

    Published in:
    JAMA Neurology, 2025, v. 82, n. 2, p. 168, doi. 10.1001/jamaneurol.2024.4400
    By:
    • Kim, Su-Hyun;
    • Gomes, Ana Beatriz Ayroza Galvão Ribeiro;
    • Schindler, Patrick;
    • Hyun, Jae-Won;
    • Kim, Ki Hoon;
    • Lee, Dong-Eun;
    • Schoeps, Vinicius Andreoli;
    • Matos, Aline de Moura Brasil;
    • Mendes, Natalia Trombini;
    • Apóstolos-Pereira, Samira Luisa Dos;
    • Callegaro, Dagoberto;
    • Lerner, Jasmine;
    • Benkert, Pascal;
    • Kuhle, Jens;
    • Ruprecht, Klemens;
    • Paul, Friedemann;
    • Pröbstel, Anne-Katrin;
    • Kim, Ho Jin
    Publication type:
    Article
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    Rituximab vs Ocrelizumab in Relapsing-Remitting Multiple Sclerosis.

    Published in:
    JAMA Neurology, 2023, v. 80, n. 8, p. 789, doi. 10.1001/jamaneurol.2023.1625
    By:
    • Roos, Izanne;
    • Hughes, Stella;
    • McDonnell, Gavin;
    • Malpas, Charles B.;
    • Sharmin, Sifat;
    • Boz, Cavit;
    • Alroughani, Raed;
    • Ozakbas, Serkan;
    • Buzzard, Katherine;
    • Skibina, Olga;
    • van der Walt, Anneke;
    • Butzkueven, Helmut;
    • Lechner-Scott, Jeannette;
    • Kuhle, Jens;
    • Terzi, Murat;
    • Laureys, Guy;
    • Van Hijfte, Liesbeth;
    • John, Nevin;
    • Grammond, Pierre;
    • Grand'Maison, Francois
    Publication type:
    Article
    11

    Comparison Between Dimethyl Fumarate, Fingolimod, and Ocrelizumab After Natalizumab Cessation.

    Published in:
    JAMA Neurology, 2023, v. 80, n. 7, p. 739, doi. 10.1001/jamaneurol.2023.1542
    By:
    • Zhu, Chao;
    • Kalincik, Tomas;
    • Horakova, Dana;
    • Zhou, Zhen;
    • Buzzard, Katherine;
    • Skibina, Olga;
    • Alroughani, Raed;
    • Izquierdo, Guillermo;
    • Eichau, Sara;
    • Kuhle, Jens;
    • Patti, Francesco;
    • Grand'Maison, Francois;
    • Hodgkinson, Suzanne;
    • Grammond, Pierre;
    • Lechner-Scott, Jeannette;
    • Butler, Ernest;
    • Prat, Alexandre;
    • Girard, Marc;
    • Duquette, Pierre;
    • Macdonell, Richard A. L.
    Publication type:
    Article
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    Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years.

    Published in:
    JAMA Neurology, 2019, v. 76, n. 11, p. 1359, doi. 10.1001/jamaneurol.2019.2137
    By:
    • Cantó, Ester;
    • Barro, Christian;
    • Zhao, Chao;
    • Caillier, Stacy J.;
    • Michalak, Zuzanna;
    • Bove, Riley;
    • Tomic, Davorka;
    • Santaniello, Adam;
    • Häring, Dieter A.;
    • Hollenbach, Jill;
    • Henry, Roland G.;
    • Cree, Bruce A. C.;
    • Kappos, Ludwig;
    • Leppert, David;
    • Hauser, Stephen L.;
    • Benkert, Pascal;
    • Oksenberg, Jorge R.;
    • Kuhle, Jens
    Publication type:
    Article
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    Altered expression of miR-17-5p in CD4.

    Published in:
    European Journal of Immunology, 2010, v. 40, n. 3, p. 888, doi. 10.1002/eji.200940032
    By:
    • Lindberg, Raija L. P.;
    • Hoffmann, Francine;
    • Mehling, Matthias;
    • Kuhle, Jens;
    • Kappos, Ludwig
    Publication type:
    Article
    17
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    Harmonized Data Quality Indicators Maintain Data Quality in Long-Term Safety Studies Using Multiple Sclerosis Registries/Data Sources: Experience from the CLARION Study.

    Published in:
    Clinical Epidemiology, 2024, v. 16, p. 717, doi. 10.2147/CLEP.S480525
    By:
    • Hillert, Jan;
    • Butzkueven, Helmut;
    • Magyari, Melinda;
    • Wergeland, Stig;
    • Moore, Nicholas;
    • Soilu-Hänninen, Merja;
    • Ziemssen, Tjalf;
    • Kuhle, Jens;
    • Pontieri, Luigi;
    • Forsberg, Lars;
    • Aarseth, Jan Harald;
    • Zhu, Chao;
    • Sicignano, Nicholas;
    • Mushnikov, Vasili;
    • Bezemer, Irene;
    • Sabidó, Meritxell
    Publication type:
    Article
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    Natalizumab in cerebrospinal fluid and breastmilk of patients with multiple sclerosis.

    Published in:
    Therapeutic Advances in Neurological Disorders, 2023, p. 1, doi. 10.1177/17562864221150040
    By:
    • Callegari, Ilaria;
    • Schneider, Mika;
    • Aebischer, Vera;
    • Voortman, Margarete M.;
    • Proschmann, Undine;
    • Ziemssen, Tjalf;
    • Lindberg, Raija;
    • Fischer-Barnicol, Bettina;
    • Khalil, Michael;
    • Kappos, Ludwig;
    • Kuhle, Jens;
    • Sanderson, Nicholas S.R.;
    • Derfuss, Tobias
    Publication type:
    Article
    25

    Evaluation of frequency, severity, and independent risk factors for recurrence of disease activity after fingolimod discontinuation in a large real-world cohort of patients with multiple sclerosis.

    Published in:
    Therapeutic Advances in Neurological Disorders, 2023, p. 1, doi. 10.1177/17562864221150312
    By:
    • Cerdá-Fuertes, Nuria;
    • Nagy, Sara;
    • Schaedelin, Sabine;
    • Sinnecker, Tim;
    • Ruberte, Esther;
    • Papadopoulou, Athina;
    • Würfel, Jens;
    • Kuhle, Jens;
    • Yaldizli, Özgür;
    • Kappos, Ludwig;
    • Derfuss, Tobias;
    • Décard, Bernhard F.
    Publication type:
    Article
    26

    Evaluation of frequency, severity, and independent risk factors for recurrence of disease activity after fingolimod discontinuation in a large real-world cohort of patients with multiple sclerosis.

    Published in:
    Therapeutic Advances in Neurological Disorders, 2023, v. 16, p. 1, doi. 10.1177/17562864221150312
    By:
    • Cerdá-Fuertes, Nuria;
    • Nagy, Sara;
    • Schaedelin, Sabine;
    • Sinnecker, Tim;
    • Ruberte, Esther;
    • Papadopoulou, Athina;
    • Würfel, Jens;
    • Kuhle, Jens;
    • Yaldizli, Özgür;
    • Kappos, Ludwig;
    • Derfuss, Tobias;
    • Décard, Bernhard F.
    Publication type:
    Article
    27

    Natalizumab in cerebrospinal fluid and breastmilk of patients with multiple sclerosis.

    Published in:
    Therapeutic Advances in Neurological Disorders, 2023, v. 16, p. 1, doi. 10.1177/17562864221150040
    By:
    • Callegari, Ilaria;
    • Schneider, Mika;
    • Aebischer, Vera;
    • Voortman, Margarete M.;
    • Proschmann, Undine;
    • Ziemssen, Tjalf;
    • Lindberg, Raija;
    • Fischer-Barnicol, Bettina;
    • Khalil, Michael;
    • Kappos, Ludwig;
    • Kuhle, Jens;
    • Sanderson, Nicholas S. R.;
    • Derfuss, Tobias
    Publication type:
    Article
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    Advanced MRI Measures of Myelin and Axon Volume Identify Repair in Multiple Sclerosis.

    Published in:
    Annals of Neurology, 2025, v. 97, n. 1, p. 134, doi. 10.1002/ana.27102
    By:
    • Sanabria‐Diaz, Gretel;
    • Cagol, Alessandro;
    • Lu, Po‐Jui;
    • Barakovic, Muhamed;
    • Ocampo‐Pineda, Mario;
    • Chen, Xinjie;
    • Weigel, Matthias;
    • Ruberte, Esther;
    • Siebenborn, Nina de Oliveira S.;
    • Galbusera, Riccardo;
    • Schädelin, Sabine;
    • Benkert, Pascal;
    • Kuhle, Jens;
    • Kappos, Ludwig;
    • Melie‐Garcia, Lester;
    • Granziera, Cristina
    Publication type:
    Article
    31

    A New Advanced MRI Biomarker for Remyelinated Lesions in Multiple Sclerosis.

    Published in:
    2022
    By:
    • Rahmanzadeh, Reza;
    • Galbusera, Riccardo;
    • Lu, Po‐Jui;
    • Bahn, Erik;
    • Weigel, Matthias;
    • Barakovic, Muhamed;
    • Franz, Jonas;
    • Nguyen, Thanh D.;
    • Spincemaille, Pascal;
    • Schiavi, Simona;
    • Daducci, Alessandro;
    • La Rosa, Francesco;
    • Absinta, Martina;
    • Sati, Pascal;
    • Bach Cuadra, Meritxell;
    • Radue, Ernst‐Wilhelm;
    • Leppert, David;
    • Kuhle, Jens;
    • Kappos, Ludwig;
    • Brück, Wolfgang
    Publication type:
    journal article
    32

    Immunological Predictors of Dimethyl Fumarate‐Induced Lymphopenia.

    Published in:
    Annals of Neurology, 2022, v. 91, n. 5, p. 676, doi. 10.1002/ana.26328
    By:
    • Diebold, Martin;
    • Galli, Edoardo;
    • Kopf, Andreas;
    • Sanderson, Nicholas;
    • Callegari, Ilaria;
    • Ingelfinger, Florian;
    • Núñez, Nicolás Gonzalo;
    • Benkert, Pascal;
    • Kappos, Ludwig;
    • Kuhle, Jens;
    • Becher, Burkhard;
    • Claassen, Manfred;
    • Derfuss, Tobias
    Publication type:
    Article
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    Serum Neurofilament Light Chain Levels in the Intensive Care Unit: Comparison between Severely Ill Patients with and without Coronavirus Disease 2019.

    Published in:
    Annals of Neurology, 2021, v. 89, n. 3, p. 610, doi. 10.1002/ana.26004
    By:
    • Sutter, Raoul;
    • Hert, Lisa;
    • De Marchis, Gian Marco;
    • Twerenbold, Raphael;
    • Kappos, Ludwig;
    • Naegelin, Yvonne;
    • Kuster, Gabriela M.;
    • Benkert, Pascal;
    • Jost, Jasmine;
    • Maceski, Aleksandra Maleska;
    • Rüegg, Stephan;
    • Siegemund, Martin;
    • Leppert, David;
    • Tschudin‐Sutter, Sarah;
    • Kuhle, Jens
    Publication type:
    Article
    35

    Prodromal symptoms of multiple sclerosis in primary care.

    Published in:
    2018
    By:
    • Disanto, Giulio;
    • Zecca, Chiara;
    • MacLachlan, Sharon;
    • Sacco, Rosaria;
    • Handunnetthi, Lahiru;
    • Meier, Ute C.;
    • Simpson, Alex;
    • McDonald, Laura;
    • Rossi, Andrea;
    • Benkert, Pascal;
    • Kuhle, Jens;
    • Ramagopalan, Sreeram V.;
    • Gobbi, Claudio
    Publication type:
    journal article
    36

    Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis.

    Published in:
    2017
    By:
    • Disanto, Giulio;
    • Barro, Christian;
    • Benkert, Pascal;
    • Naegelin, Yvonne;
    • Schädelin, Sabine;
    • Giardiello, Antonella;
    • Zecca, Chiara;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Leppert, David;
    • Kappos, Ludwig;
    • Gobbi, Claudio;
    • Kuhle, Jens;
    • Lorscheider, Johannes;
    • Yaldizli, Özgür;
    • Derfuss, Tobias;
    • Achtnichts, Lutz;
    • Nedeltchev, Krassen;
    • Kamm, Christian P;
    • Salmen, Anke
    Publication type:
    journal article
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    Prognostic Value of Serum Neurofilament Light Chain for Disease Activity and Worsening in Patients With Relapsing Multiple Sclerosis: Results From the Phase 3 ASCLEPIOS I and II Trials.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.852563
    By:
    • Ziemssen, Tjalf;
    • Arnold, Douglas L.;
    • Alvarez, Enrique;
    • Cross, Anne H.;
    • Willi, Roman;
    • Li, Bingbing;
    • Kukkaro, Petra;
    • Kropshofer, Harald;
    • Ramanathan, Krishnan;
    • Merschhemke, Martin;
    • Kieseier, Bernd;
    • Su, Wendy;
    • Häring, Dieter A.;
    • Hauser, Stephen L.;
    • Kappos, Ludwig;
    • Kuhle, Jens
    Publication type:
    Article
    44

    Baseline Inflammatory Status Reveals Dichotomic Immune Mechanisms Involved In Primary-Progressive Multiple Sclerosis Pathology.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.842354
    By:
    • Fernández-Velasco, José I.;
    • Monreal, Enric;
    • Kuhle, Jens;
    • Meca-Lallana, Virginia;
    • Meca-Lallana, José;
    • Izquierdo, Guillermo;
    • Oreja-Guevara, Celia;
    • Gascón-Giménez, Francisco;
    • Sainz de la Maza, Susana;
    • Walo-Delgado, Paulette E.;
    • Lapuente-Suanzes, Paloma;
    • Maceski, Aleksandra;
    • Rodríguez-Martín, Eulalia;
    • Roldán, Ernesto;
    • Villarrubia, Noelia;
    • Saiz, Albert;
    • Blanco, Yolanda;
    • Diaz-Pérez, Carolina;
    • Valero-López, Gabriel;
    • Diaz-Diaz, Judit
    Publication type:
    Article
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    Neurofilament levels are associated with blood–brain barrier integrity, lymphocyte extravasation, and risk factors following the first demyelinating event in multiple sclerosis.

    Published in:
    Multiple Sclerosis Journal, 2021, v. 27, n. 2, p. 220, doi. 10.1177/1352458520912379
    By:
    • Uher, Tomas;
    • McComb, Mason;
    • Galkin, Shery;
    • Srpova, Barbora;
    • Oechtering, Johanna;
    • Barro, Christian;
    • Tyblova, Michaela;
    • Bergsland, Niels;
    • Krasensky, Jan;
    • Dwyer, Michael;
    • Havrdova, Eva Kubala;
    • Posova, Helena;
    • Vaneckova, Manuela;
    • Zivadinov, Robert;
    • Horakova, Dana;
    • Kuhle, Jens;
    • Ramanathan, Murali
    Publication type:
    Article