Works matching AU Kufareva, Irina

Results: 32

Tyrosine Phosphorylation of the Gα-Interacting Protein GIV Promotes Activation of Phosphoinositide 3-Kinase During Cell Migration.

Published in:

Science Signaling, 2011, v. 4, n. 192, p. 1, doi. 10.1126/scisignal.2002049

By:

Lin, Changsheng;
Ear, Jason;
Pavlova, Yelena;
Mittal, Yash;
Kufareva, Irina;
Ghassemian, Majid;
Abagyan, Ruben;
Garcia-Marcos, Mikel;
Ghosh, Pradipta

Publication type:

Article

Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5).

Published in:

Theoretical Biology & Medical Modelling, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4682-10-56

By:

Lindin, Inger;
Yimingjiang Wuxiuer;
Kufareva, Irina;
Abagyan, Ruben;
Moens, Ugo;
Sylte, Ingebrigt;
Ravna, Aina Westrheim

Publication type:

Article

Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity.

Published in:

PLoS Biology, 2020, v. 18, n. 4, p. 1, doi. 10.1371/journal.pbio.3000656

By:

Ngo, Tony;
Stephens, Bryan S.;
Gustavsson, Martin;
Holden, Lauren G.;
Abagyan, Ruben;
Handel, Tracy M.;
Kufareva, Irina

Publication type:

Article

A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE).

Published in:

FASEB Journal, 2008, v. 22, p. 333, doi. 10.1096/fasebj.22.2_supplement.333

By:

Bottegoni, Giovanni;
Kufareva, Irina;
Totrov, Maxim;
Abagyan, Ruben

Publication type:

Article

Druggable exosites of the human kino-pocketome.

Published in:

Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 3, p. 219, doi. 10.1007/s10822-019-00276-y

By:

Nicola, George;
Kufareva, Irina;
Ilatovskiy, Andrey V.;
Abagyan, Ruben

Publication type:

Article

Discovery of novel membrane binding structures and functions<sup>1</sup>.

Published in:

Biochemistry & Cell Biology, 2014, v. 92, n. 6, p. 555, doi. 10.1139/bcb-2014-0074

By:

Kufareva, Irina;
Lenoir, Marc;
Dancea, Felician;
Sridhar, Pooja;
Raush, Eugene;
Bissig, Christin;
Gruenberg, Jean;
Abagyan, Ruben;
Overduin, Michael

Publication type:

Article

Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors.

Published in:

Chemical Biology & Drug Design, 2013, v. 81, n. 6, p. 695, doi. 10.1111/cbdd.12116

By:

Gabrielsen, Mari;
Wołosewicz, Karol;
Zawadzka, Anna;
Kossakowski, Jerzy;
Nowak, Gabriel;
Wolak, Małgorzata;
Stachowicz, Katarzyna;
Siwek, Agata;
Ravna, Aina W.;
Kufareva, Irina;
Kozerski, Lech;
Bednarek, Elżbieta;
Sitkowski, Jerzy;
Bocian, Wojciech;
Abagyan, Ruben;
Bojarski, Andrzej J.;
Sylte, Ingebrigt;
Chilmonczyk, Zdzisław

Publication type:

Article

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

Published in:

Nature Reviews Cancer, 2013, v. 13, n. 6, p. 412, doi. 10.1038/nrc3521

By:

O'Hayre, Morgan;
Vázquez-Prado, José;
Kufareva, Irina;
Stawiski, Eric W.;
Handel, Tracy M.;
Seshagiri, Somasekar;
Gutkind, J. Silvio

Publication type:

Article

Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.

Published in:

Biochemical Journal, 2013, v. 453, n. 2, p. 219, doi. 10.1042/BJ20130398

By:

DAVYDOV, Dmitri R.;
DAVYDOVA, Nadezhda Y.;
SINEVA, Elena V.;
KUFAREVA, Irina;
HALPERT, James R.

Publication type:

Article

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-52141-5

By:

Kufareva, Irina;
Bestgen, Benoit;
Brear, Paul;
Prudent, Renaud;
Laudet, Béatrice;
Moucadel, Virginie;
Ettaoussi, Mohamed;
Sautel, Celine F.;
Krimm, Isabelle;
Engel, Matthias;
Filhol, Odile;
Borgne, Marc Le;
Lomberget, Thierry;
Cochet, Claude;
Abagyan, Ruben

Publication type:

Article

Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.

Published in:

Immunology & Cell Biology, 2015, v. 93, n. 4, p. 372, doi. 10.1038/icb.2015.15

By:

Kufareva, Irina;
Salanga, Catherina L;
Handel, Tracy M

Publication type:

Article

Growth factor–dependent phosphorylation of Gα<sub>i</sub> shapes canonical signaling by G protein–coupled receptors.

Published in:

Science Signaling, 2024, v. 17, n. 839, p. 1, doi. 10.1126/scisignal.ade8041

By:

Roy, Suchismita;
Sinha, Saptarshi;
Silas, Ananta James;
Ghassemian, Majid;
Kufareva, Irina;
Ghosh, Pradipta

Publication type:

Article

The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms.

Published in:

Science Signaling, 2023, v. 16, n. 770, p. 1, doi. 10.1126/scisignal.abo4314

By:

Shroka, Thomas M.;
Kufareva, Irina;
Salanga, Catherina L.;
Handel, Tracy M.

Publication type:

Article

Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.

Published in:

Science Signaling, 2020, v. 13, n. 640, p. 1, doi. 10.1126/scisignal.aay5024

By:

Stephens, Bryan S.;
Ngo, Tony;
Kufareva, Irina;
Handel, Tracy M.

Publication type:

Article

Negative allosteric modulators of the human calcium-sensing receptor bind to overlapping and distinct sites within the 7-transmembrane domain.

Published in:

2020

By:

Josephs, Tracy M.;
Keller, Andrew N.;
Khajehali, Elham;
DeBono, Aaron;
Langmead, Christopher J.;
Conigrave, Arthur D.;
Capuano, Ben;
Kufareva, Irina;
Gregory, Karen J.;
Leach, Katie

Publication type:

journal article

Identifying ligands at orphan GPCRs: current status using structure-based approaches.

Published in:

2016

By:

Ngo, Tony;
Kufareva, Irina;
Coleman, James LJ;
Graham, Robert M;
Abagyan, Ruben;
Smith, Nicola J

Publication type:

journal article

Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily.

Published in:

Membranes, 2015, v. 5, n. 4, p. 646, doi. 10.3390/membranes5040646

By:

Lenoir, Marc;
Kufareva, Irina;
Abagyan, Ruben;
Overduin, Michael

Publication type:

Article

Pocketome: an encyclopedia of small-molecule binding sites in 4D.

Published in:

Nucleic Acids Research, 2012, p. D535, doi. 10.1093/nar/gkr825

By:

Kufareva, Irina;
Ilatovskiy, Andrey V.;
Abagyan, Ruben

Publication type:

Article

Structural basis of ligand interaction with atypical chemokine receptor 3.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 14135, doi. 10.1038/ncomms14135

By:

Gustavsson, Martin;
Wang, Liwen;
van Gils, Noortje;
Stephens, Bryan S.;
Zhang, Penglie;
Schall, Thomas J.;
Yang, Sichun;
Abagyan, Ruben;
Chance, Mark R.;
Kufareva, Irina;
Handel, Tracy M.

Publication type:

Article

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.

Published in:

Science Signaling, 2018, v. 11, n. 519, p. 1, doi. 10.1126/scisignal.aao4220

By:

Aznar, Nicolas;
Ear, Jason;
Dunkel, Ying;
Sun, Nina;
Satterfield, Kendall;
He, Fang;
Kalogriopoulos, Nicholas A.;
Lopez-Sanchez, Inmaculada;
Ghassemian, Majid;
Sahoo, Debashis;
Kufareva, Irina;
Ghosh, Pradipta

Publication type:

Article

Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 5, p. 459, doi. 10.1007/s10822-010-9362-4

By:

So-Jung Park;
Kufareva, Irina;
Abagyan, Ruben

Publication type:

Article

A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE).

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 5, p. 311, doi. 10.1007/s10822-008-9188-5

By:

Bottegoni, Giovanni;
Kufareva, Irina;
Totrov, Maxim;
Abagyan, Ruben

Publication type:

Article

A General Method for Site Specific Fluorescent Labeling of Recombinant Chemokines.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0081454

By:

Kawamura, Tetsuya;
Stephens, Bryan;
Qin, Ling;
Yin, Xin;
Dores, Michael R.;
Smith, Thomas H.;
Grimsey, Neil;
Abagyan, Ruben;
Trejo, JoAnn;
Kufareva, Irina;
Fuster, Mark M.;
Salanga, Catherina L.;
Handel, Tracy M.

Publication type:

Article

Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical Scaffolds.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056150

By:

Katiyar, Samiksha;
Kufareva, Irina;
Behera, Ranjan;
Thomas, Sarah M.;
Ogata, Yuko;
Pollastri, Michael;
Abagyan, Ruben;
Mensa-Wilmot, Kojo

Publication type:

Article

Quantum mechanics approaches to drug research in the era of structural chemogenomics.

Published in:

International Journal of Quantum Chemistry, 2013, v. 113, n. 12, p. 1669, doi. 10.1002/qua.24400

By:

Ilatovskiy, Andrey V.;
Abagyan, RubEN;
Kufareva, Irina

Publication type:

Article

PIER: Protein interface recognition for structural proteomics.

Published in:

Proteins, 2007, v. 67, n. 2, p. 400, doi. 10.1002/prot.21233

By:

Kufareva, Irina;
Budagyan, Levon;
Raush, Eugene;
Totrov, Maxim;
Abagyan, Ruben

Publication type:

Article

In Silico Identification and Pharmacological Evaluation of Novel Endocrine Disrupting Chemicals That Act via the Ligand-Binding Domain of the Estrogen Receptor α.

Published in:

Toxicological Sciences, 2014, v. 141, n. 1, p. 188, doi. 10.1093/toxsci/kfu114

By:

McRobb, Fiona M.;
Kufareva, Irina;
Abagyan, Ruben

Publication type:

Article

AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.20795

By:

Aznar, Nicolas;
Patel, Arjun;
Rohena, Cristina C.;
Ying Dunkel;
Joosen, Linda P.;
Taupin, Vanessa;
Kufareva, Irina;
Farquhar, Marilyn G.;
Ghosh, Pradipta

Publication type:

Article

Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.

Published in:

PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0214901

By:

Chahal, Kirti Kandhwal;
Li, Jie;
Kufareva, Irina;
Parle, Milind;
Durden, Donald L.;
Wechsler-Reya, Robert J.;
Chen, Clark C.;
Abagyan, Ruben

Publication type:

Article

kboolnet: a toolkit for the verification, validation, and visualization of reaction-contingency (rxncon) models.

Published in:

BMC Bioinformatics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12859-023-05329-6

By:

Carretero Chavez, Willow;
Krantz, Marcus;
Klipp, Edda;
Kufareva, Irina

Publication type:

Article

Differential activity and selectivity of N‐terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors.

Published in:

Journal of Leukocyte Biology, 2020, v. 107, n. 6, p. 1123, doi. 10.1002/JLB.2MA0320-383RR

By:

Jaracz‐Ros, Agnieszka;
Bernadat, Guillaume;
Cutolo, Pasquale;
Gallego, Carmen;
Gustavsson, Martin;
Cecon, Erika;
Baleux, Françoise;
Kufareva, Irina;
Handel, Tracy M.;
Bachelerie, Françoise;
Levoye, Angélique

Publication type:

Article

The GAPs, GEFs, GDIs and…now, GEMs: New kids on the heterotrimeric G protein signaling block.

Published in:

Cell Cycle, 2017, v. 16, n. 7, p. 607, doi. 10.1080/15384101.2017.1282584

By:

Ghosh, Pradipta;
Rangamani, Padmini;
Kufareva, Irina

Publication type:

Article