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Predictive metabolic networks reveal sex‐ and APOE genotype‐specific metabolic signatures and drivers for precision medicine in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 2, p. 518, doi. 10.1002/alz.12675
By:
- Chang, Rui;
- Trushina, Eugenia;
- Zhu, Kuixi;
- Zaidi, Syed Shujaat Ali;
- Lau, Branden M.;
- Kueider‐Paisley, Alexandra;
- Moein, Sara;
- He, Qianying;
- Alamprese, Melissa L.;
- Vagnerova, Barbora;
- Tang, Andrew;
- Vijayan, Ramachandran;
- Liu, Yanyun;
- Saykin, Andrew J.;
- Brinton, Roberta D.;
- Kaddurah‐Daouk, Rima
Publication type:
Article
Transcriptomics, metabolomics, lipidomics, metabolic flux and mGWAS analyses of sphingolipid pathway highlights novel drugs for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056152
By:
- Baloni, Priyanka;
- Arnold, Matthias;
- Moreno, Herman;
- Nho, Kwangsik;
- Kastenmüller, Gabi;
- Suhre, Karsten;
- Buitrago, Luna;
- Louie, Gregory;
- Kueider‐Paisley, Alexandra;
- Saykin, Andrew J.;
- Ekroos, Kim;
- Meikle, Peter J.;
- Huynh, Kevin;
- Funk, Cory C.;
- Hood, Leroy;
- Price, Nathan D.;
- Baillie, Rebecca;
- Han, Xianlin;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Investigating the importance of acylcarnitines in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056647
By:
- Baloni, Priyanka;
- Nho, Kwangsik;
- Arnold, Matthias;
- Louie, Gregory;
- Kueider‐Paisley, Alexandra;
- Saykin, Andrew J.;
- Ekroos, Kim;
- Funk, Cory;
- Hood, Leroy;
- Price, Nathan D;
- Baillie, Rebecca;
- Kastenmüller, Gabi;
- Han, Xianlin;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Serum metabolome informs neuroimaging biomarkers for Alzheimer's disease: Genome‐metabolome‐phenome: Towards an integrated molecular atlas for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045596
By:
- Nho, Kwangsik;
- Kueider‐Paisley, Alexandra;
- Arnold, Matthias;
- Dehkordi, Siamak Mahmoudian;
- Risacher, Shannon L.;
- Louie, Gregory;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- Kastenmüller, Gabi;
- Doraiswamy, P. Murali;
- Kaddurah‐Daouk, Rima F.;
- Saykin, Andrew J.
Publication type:
Article
Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 9, p. 1234, doi. 10.1002/alz.12110
By:
- Kling, Mitchel A.;
- Goodenowe, Dayan B.;
- Senanayake, Vijitha;
- MahmoudianDehkordi, Siamak;
- Arnold, Matthias;
- Massaro, Tyler J.;
- Baillie, Rebecca;
- Han, Xianlin;
- Leung, Yuk‐Yee;
- Saykin, Andrew J.;
- Nho, Kwangsik;
- Kueider‐Paisley, Alexandra;
- Tenenbaum, Jessica D.;
- Wang, Li‐San;
- Shaw, Leslie M.;
- Trojanowski, John Q.;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
P1‐386: ASSOCIATION OF SERUM‐BASED PLASMALOGENS WITH NEUROIMAGING AND GENETIC VARIATION IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P403, doi. 10.1016/j.jalz.2019.06.941
By:
- Nho, Kwangsik;
- Kling, Mitchel A.;
- MahmoudianDehkordi, Siamak;
- Arnold, Matthias;
- Goodenowe, Dayan B.;
- Senanayake, Vijitha;
- Risacher, Shannon L.;
- Kueider-Paisley, Alexandra;
- Louie, Gregory;
- Baillie, Rebecca;
- Han, Xianlin;
- Kastenmüller, Gabi;
- Doraiswamy, P. Murali;
- Saykin, Andrew J.;
- Kaddurah-Daouk, Rima F.
Publication type:
Article
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 2, p. 232, doi. 10.1016/j.jalz.2018.08.012
By:
- Nho, Kwangsik;
- Kueider‐Paisley, Alexandra;
- MahmoudianDehkordi, Siamak;
- Arnold, Matthias;
- Risacher, Shannon L.;
- Louie, Gregory;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- Kastenmüller, Gabi;
- Jia, Wei;
- Xie, Guoxiang;
- Ahmad, Shahzad;
- Hankemeier, Thomas;
- van Duijn, Cornelia M.;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Weiner, Michael W.;
- Doraiswamy, P. Murali;
- Saykin, Andrew J.
Publication type:
Article
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 1, p. 76, doi. 10.1016/j.jalz.2018.07.217
By:
- MahmoudianDehkordi, Siamak;
- Arnold, Matthias;
- Nho, Kwangsik;
- Ahmad, Shahzad;
- Jia, Wei;
- Xie, Guoxiang;
- Louie, Gregory;
- Kueider‐Paisley, Alexandra;
- Moseley, M. Arthur;
- Thompson, J. Will;
- St John Williams, Lisa;
- Tenenbaum, Jessica D.;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- Bhattacharyya, Sudeepa;
- Toledo, Jon B.;
- Schafferer, Simon;
- Klein, Sebastian;
- Koal, Therese
Publication type:
Article
F3‐02‐01: ALTERED BILE ACID METABOLITES IN MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE: RELATION TO NEUROIMAGING AND CSF BIOMARKERS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P997, doi. 10.1016/j.jalz.2018.06.2744
By:
- Nho, Kwangsik;
- MahmoudianDehkordi, Siamak;
- Kueider-Paisley, Alexandra;
- Arnold, Matthias;
- Louie, Gregory;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- Kastenmüller, Gabi;
- Kling, Mitchel A.;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Weiner, Michael;
- Doraiswamy, P. Murali;
- Saykin, Andrew J.;
- Kaddurah-Daouk, Rima F.;
- Risacher, Shannon L.
Publication type:
Article
F3‐02‐04: SERUM INDICES OF ETHANOLAMINE PLASMALOGENS AND PHOSPHATIDE METABOLISM IN THE COMBINED ADNI‐1/GO/2 COHORT: DOES THE LIVER CONTRIBUTE TO AD RISK BY FAILING TO SUPPLY KEY LIPIDS TO THE BRAIN?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P998, doi. 10.1016/j.jalz.2018.06.2747
By:
- Kling, Mitchel A.;
- Goodenowe, Dayan B.;
- Senanayake, Vijitha;
- MahmoudianDehkordi, Siamak;
- Baillie, Rebecca;
- Han, Xianlin;
- Kueider-Paisley, Alexandra;
- Kaddurah-Daouk, Rima F.
Publication type:
Article
Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts.
Published in:
Scientific Data, 2019, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41597-019-0181-8
By:
- St. John-Williams, Lisa;
- Mahmoudiandehkordi, Siamak;
- Arnold, Matthias;
- Massaro, Tyler;
- Blach, Colette;
- Kastenmüller, Gabi;
- Louie, Gregory;
- Kueider-Paisley, Alexandra;
- Han, Xianlin;
- Baillie, Rebecca;
- Motsinger-Reif, Alison A.;
- Rotroff, Daniel;
- Nho, Kwangsik;
- Saykin, Andrew J.;
- Risacher, Shannon L.;
- Koal, Therese;
- Moseley, M. Arthur;
- Tenenbaum, Jessica D.;
- Thompson, J. Will;
- Kaddurah-Daouk, Rima
Publication type:
Article
Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer's disease.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67177-5
By:
- Liang, Nuanyi;
- Nho, Kwangsik;
- Newman, John W.;
- Arnold, Matthias;
- Huynh, Kevin;
- Meikle, Peter J.;
- Borkowski, Kamil;
- Kaddurah-Daouk, Rima;
- Kueider-Paisley, Alexandra;
- Doraiswamy, P. Murali;
- Blach, Colette;
- Moseley, Arthur;
- Mahmoudiandehkhordi, Siamak;
- Welsh-Balmer, Kathleen;
- Plassman, Brenda;
- Saykin, Andrew;
- Risacher, Shannon;
- Kastenmüller, Gabi;
- Han, Xianlin;
- Baillie, Rebecca
Publication type:
Article
Serum Bile Acids Improve Prediction of Alzheimer's Progression in a Sex‐Dependent Manner.
Published in:
Advanced Science, 2024, v. 11, n. 9, p. 1, doi. 10.1002/advs.202306576
By:
- Chen, Tianlu;
- Wang, Lu;
- Xie, Guoxiang;
- Kristal, Bruce S.;
- Zheng, Xiaojiao;
- Sun, Tao;
- Arnold, Matthias;
- Louie, Gregory;
- Li, Mengci;
- Wu, Lirong;
- Mahmoudiandehkordi, Siamak;
- Sniatynski, Matthew J.;
- Borkowski, Kamil;
- Guo, Qihao;
- Kuang, Junliang;
- Wang, Jieyi;
- Nho, Kwangsik;
- Ren, Zhenxing;
- Kueider‐Paisley, Alexandra;
- Blach, Colette
Publication type:
Article
Comparison of Approaches for Equating Different Versions of the Mini-Mental State Examination Administered in 22 Studies.
Published in:
American Journal of Epidemiology, 2019, v. 188, n. 12, p. 2202, doi. 10.1093/aje/kwz228
By:
- Gross, Alden L;
- Kueider-Paisley, Alexandra M;
- Sullivan, Campbell;
- Schretlen, David;
- Initiative, International Neuropsychological Normative Database
Publication type:
Article
Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers.
Published in:
JAMA Network Open, 2019, v. 2, n. 7, p. e197978, doi. 10.1001/jamanetworkopen.2019.7978
By:
- Nho, Kwangsik;
- Kueider-Paisley, Alexandra;
- Ahmad, Shahzad;
- MahmoudianDehkordi, Siamak;
- Arnold, Matthias;
- Risacher, Shannon L.;
- Louie, Gregory;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- Kastenmüller, Gabi;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Weiner, Michael W.;
- Doraiswamy, P. Murali;
- van Duijn, Cornelia;
- Saykin, Andrew J.;
- Kaddurah-Daouk, Rima
Publication type:
Article
Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression.
Published in:
Brain Communications, 2021, v. 3, n. 3, p. 1, doi. 10.1093/braincomms/fcab139
By:
- Kwangsik Nho;
- Kueider-Paisley, Alexandra;
- Arnold, Matthias;
- MahmoudianDehkordi, Siamak;
- Risacher, Shannon L.;
- Louie, Gregory;
- Blach, Colette;
- Baillie, Rebecca;
- Xianlin Han;
- Kastenmüller, Gabi;
- Doraiswamy, P. Murali;
- Kaddurah-Daouk, Rima;
- Saykin, Andrew J.
Publication type:
Article
Peripheral serum metabolomic profiles inform central cognitive impairment.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-70703-w
By:
- Wang, Jingye;
- Wei, Runmin;
- Xie, Guoxiang;
- Arnold, Matthias;
- Kueider-Paisley, Alexandra;
- Louie, Gregory;
- Mahmoudian Dehkordi, Siamak;
- Blach, Colette;
- Baillie, Rebecca;
- Han, Xianlin;
- De Jager, Philip L.;
- Bennett, David A.;
- Kaddurah-Daouk, Rima;
- Jia, Wei
Publication type:
Article
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01119-z
By:
- Ko, Yi-An;
- Billheimer, Jeffrey T.;
- Lyssenko, Nicholas N.;
- Kueider-Paisley, Alexandra;
- Wolk, David A.;
- Arnold, Steven E.;
- Leung, Yuk Yee;
- Shaw, Leslie M.;
- Trojanowski, John Q.;
- Kaddurah-Daouk, Rima F.;
- Kling, Mitchel A.;
- Rader, Daniel J.
Publication type:
Article
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04011-6
By:
- Baloni, Priyanka;
- Arnold, Matthias;
- Buitrago, Luna;
- Nho, Kwangsik;
- Moreno, Herman;
- Huynh, Kevin;
- Brauner, Barbara;
- Louie, Gregory;
- Kueider-Paisley, Alexandra;
- Suhre, Karsten;
- Saykin, Andrew J.;
- Ekroos, Kim;
- Meikle, Peter J.;
- Hood, Leroy;
- Price, Nathan D.;
- The Alzheimer's Disease Metabolomics Consortium;
- Blach, Colette;
- Kaddurah-Daouk, Rima;
- Doraiswamy, Murali;
- Mahmoudiandehkordi, Siamak
Publication type:
Article
Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14959-w
By:
- Arnold, Matthias;
- Nho, Kwangsik;
- Kueider-Paisley, Alexandra;
- Massaro, Tyler;
- Huynh, Kevin;
- Brauner, Barbara;
- MahmoudianDehkordi, Siamak;
- Louie, Gregory;
- Moseley, M. Arthur;
- Thompson, J. Will;
- John-Williams, Lisa St;
- Tenenbaum, Jessica D.;
- Blach, Colette;
- Chang, Rui;
- Brinton, Roberta D.;
- Baillie, Rebecca;
- Han, Xianlin;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Martins, Ralph
Publication type:
Article

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