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A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice.
- Published in:
- EMBO Molecular Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.15252/emmm.201809396
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- Publication type:
- Article
Long-Term Assessment of AAV-Mediated Zinc Finger Nuclease Expression in the Mouse Brain.
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- Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00142
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- Publication type:
- Article
Optogenetic stimulation of the auditory pathway.
- Published in:
- 2014
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- Publication type:
- journal article
Optogenetic stimulation of the auditory pathway.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 1114, doi. 10.1172/JCI69050
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- Publication type:
- Article
Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.
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- Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00239
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- Publication type:
- Article
Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity.
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- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00049
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- Publication type:
- Article
MICROGLIAL EXOSOMES PROPAGATE TAU PROTEIN FROM THE ENTORHINAL CORTEX TO THE HIPPOCAMPUS: AN EARLY PATHOPHYSIOLOGY OF ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P339, doi. 10.1016/j.jalz.2016.06.624
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- Publication type:
- Article
NEURON-SPECIFIC TRANSGENE DELIVERY TO THE BRAIN USING MRI-GUIDED FOCUSED ULTRASOUND.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P719, doi. 10.1016/j.jalz.2016.06.1415
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- Publication type:
- Article
The amyloid-GSK3-tau connection to neurodegeneration revealed by combining transgenic and viral models
- Published in:
- 2009
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- Publication type:
- Abstract
P1-005: AAV-based paradigm for amyloid and Tau pathology as in vivo model for Alzheimer's disease
- Published in:
- 2008
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- Publication type:
- Abstract
Single-spike detection in vitro and in vivo with a genetic Ca<sup>2+</sup> sensor.
- Published in:
- Nature Methods, 2008, v. 5, n. 9, p. 797, doi. 10.1038/nmeth.1242
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- Publication type:
- Article
Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease.
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- International Journal of Alzheimer's Disease, 2010, v. 2010, p. 1, doi. 10.4061/2010/573138
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- Publication type:
- Article
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.
- Published in:
- PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0143954
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- Publication type:
- Article
Neuronal Expression of the Human Neuropeptide S Receptor NPSR1 Identifies NPS-Induced Calcium Signaling Pathways.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117319
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- Publication type:
- Article
Overexpression of BDNF Increases Excitability of the Lumbar Spinal Network and Leads to Robust Early Locomotor Recovery in Completely Spinalized Rats.
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- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088833
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- Publication type:
- Article
Tauopathy Differentially Affects Cell Adhesion Molecules in Mouse Brain: Early Down-Regulation of Nectin-3 in Stratum Lacunosum Moleculare
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063589
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- Publication type:
- Article
Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats.
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- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022333
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- Publication type:
- Article
Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons.
- Published in:
- PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019745
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- Publication type:
- Article
AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice.
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- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007280
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- Publication type:
- Article
A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity.
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- EMBO Journal, 2011, v. 30, n. 14, p. 2793, doi. 10.1038/emboj.2011.202
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- Publication type:
- Article
Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models.
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- EMBO Journal, 2009, v. 28, n. 20, p. 3256, doi. 10.1038/emboj.2009.257
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- Publication type:
- Article
Increased GABAergic Efficacy of Central Amygdala Projections to Neuropeptide S Neurons in the Brainstem During Fear Memory Retrieval.
- Published in:
- Neuropsychopharmacology, 2015, v. 40, n. 12, p. 2753, doi. 10.1038/npp.2015.125
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- Publication type:
- Article
Axonal autophagic vesicle transport in the rat optic nerve in vivo under normal conditions and during acute axonal degeneration.
- Published in:
- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01791-2
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- Publication type:
- Article
Fibroblast growth factor 9 (FGF9)‐mediated neurodegeneration: Implications for progressive multiple sclerosis?
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- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 5, p. 1, doi. 10.1111/nan.12935
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- Publication type:
- Article
α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals.
- Published in:
- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.868790
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- Publication type:
- Article
Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.
- Published in:
- Brain: A Journal of Neurology, 2014, v. 137, n. 1, p. 78, doi. 10.1093/brain/awt323
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- Publication type:
- Article
Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
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- 2012
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- Publication type:
- journal article
Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease.
- Published in:
- Brain: A Journal of Neurology, 2012, v. 135, n. 8, p. 2428, doi. 10.1093/brain/aws177
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- Publication type:
- Article
Adeno-associated virus-mediated L1 expression promotes functional recovery after spinal cord injury.
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- Brain: A Journal of Neurology, 2007, v. 130, n. 4, p. 954, doi. 10.1093/brain/awm049
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- Publication type:
- Article
Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo.
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- Brain: A Journal of Neurology, 2005, v. 128, n. 3, p. 550, doi. 10.1093/brain/awh382
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- Publication type:
- Article
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
- Published in:
- 2013
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- Publication type:
- journal article
Reply.
- Published in:
- Annals of Neurology, 2013, v. 74, n. 2, p. 307, doi. 10.1002/ana.23935
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- Publication type:
- Article
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
- Published in:
- Annals of Neurology, 2013, v. 74, n. 1, p. 109, doi. 10.1002/ana.23905
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- Publication type:
- Article
Dopamine promotes the neurodegenerative potential of β‐synuclein.
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- Journal of Neurochemistry, 2021, v. 156, n. 5, p. 674, doi. 10.1111/jnc.15134
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- Publication type:
- Article
AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.
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- Journal of Neurochemistry, 2015, v. 134, n. 2, p. 261, doi. 10.1111/jnc.13102
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- Publication type:
- Article
Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo.
- Published in:
- Experimental Brain Research, 2005, v. 161, n. 3, p. 335, doi. 10.1007/s00221-004-2077-9
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- Publication type:
- Article
Sumoylation inhibits α-synuclein aggregation and toxicity.
- Published in:
- Journal of Cell Biology, 2011, v. 194, n. 1, p. 49, doi. 10.1083/jcb.201010117
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- Publication type:
- Article
Sumoylation inhibits α-synuclein aggregation and toxicity.
- Published in:
- Journal of Cell Biology, 2011, v. 193, n. 8, p. 49, doi. 10.1083/jcb.201010117
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- Publication type:
- Article
Syntenin-knock out reduces exosome turnover and viral transduction.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81697-4
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- Publication type:
- Article
Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81046-5
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- Publication type:
- Article
Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma.
- Published in:
- Cell Death & Differentiation, 1999, v. 6, n. 4, p. 370, doi. 10.1038/sj.cdd.4400503
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- Publication type:
- Article
Dementia with Lewy bodies—associated ß-synuclein mutations V70M and P123H cause mutation-specific neuropathological lesions.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 3/4, p. 247, doi. 10.1093/hmg/ddab036
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- Publication type:
- Article
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 1, p. 31, doi. 10.1093/hmg/ddy326
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- Publication type:
- Article
Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 19, p. 5451, doi. 10.1093/hmg/ddv271
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- Publication type:
- Article
Thalamocortical Connections Drive Intracortical Activation of Functional Columns in the Mislaminated Reeler Somatosensory Cortex.
- Published in:
- Cerebral Cortex, 2016, v. 26, n. 2, p. 820, doi. 10.1093/cercor/bhv257
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- Publication type:
- Article
Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 12, p. 1, doi. 10.1038/s41419-019-2133-9
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- Publication type:
- Article
Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.
- Published in:
- 2018
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- Publication type:
- Correction Notice
Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.
- Published in:
- Cell Death & Disease, 2016, v. 7, n. 9, p. e2359, doi. 10.1038/cddis.2016.263
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- Publication type:
- Article
Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo.
- Published in:
- European Journal of Neuroscience, 2002, v. 15, n. 4, p. 637, doi. 10.1046/j.1460-9568.2002.01893.x
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- Publication type:
- Article
Pre-existing immunity to adeno-associated virus (AAV)2 limits transgene expression following intracerebral AAV2-based gene delivery in a 6-hydroxydopamine model of Parkinson's disease.
- Published in:
- Journal of Gene Medicine, 2014, v. 16, n. 9/10, p. 300, doi. 10.1002/jgm.2779
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- Publication type:
- Article