Works by Krystal, Gerald

Results: 30

Saponins in soy reduce NNK-induced lung cancer by increasing plasma isoflavone levels.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-97687-9

By:

Elisia, Ingrid;
Yeung, Michelle;
Kowalski, Sara;
Wong, Amy;
Dietrich, Colton;
Wu, Samantha;
Chang, Vianne;
Adomat, Hans;
Krystal, Gerald

Publication type:

Article

Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity.

Published in:

EMBO Journal, 2000, v. 19, n. 12, p. 2793, doi. 10.1093/emboj/19.12.2793

By:

Pasquet, Jean-Max;
Quek, Lynn;
Stevens, Christian;
Bobe, Régis;
Huber, Michael;
Duronio, Vincent;
Krystal, Gerald;
Watson, Steve P.

Publication type:

Article

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

Published in:

EMBO Journal, 1998, v. 17, n. 24, p. 7311, doi. 10.1093/emboj/17.24.7311

By:

Huber, Michael;
Helgason, Chery D.;
Scheid, Michael P.;
Duronio, Vincent;
Humphries, R. Keith;
Krystal, Gerald

Publication type:

Article

Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228633

By:

Elisia, Ingrid;
Lam, Vivian;
Cho, Brandon;
Hay, Mariah;
Li, Michael Yu;
Kapeluto, Jordanna;
Elliott, Tom;
Harris, David;
Bu, Luke;
Jia, William;
Leung, Hilary;
Mohn, William;
Krystal, Gerald

Publication type:

Article

All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168072

By:

Ho, Victor W.;
Hofs, Elyse;
Elisia, Ingrid;
Lam, Vivian;
Hsu, Brian E.;
Lai, June;
Luk, Beryl;
Samudio, Ismael;
Krystal, Gerald

Publication type:

Article

DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0152538

By:

Elisia, Ingrid;
Nakamura, Hisae;
Lam, Vivian;
Hofs, Elyse;
Cederberg, Rachel;
Cait, Jessica;
Hughes, Michael R.;
Lee, Leora;
Jia, William;
Adomat, Hans H.;
Guns, Emma S.;
McNagny, Kelly M.;
Samudio, Ismael;
Krystal, Gerald

Publication type:

Article

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development.

Published in:

OncoImmunology, 2022, v. 11, n. 1, p. 1, doi. 10.1080/2162402X.2021.2010905

By:

Melese, Etienne S.;
Franks, Elizabeth;
Cederberg, Rachel A.;
Harbourne, Bryant T.;
Shi, Rocky;
Wadsworth, Brennan J.;
Collier, Jenna L.;
Halvorsen, Elizabeth C.;
Johnson, Fraser;
Luu, Jennifer;
Min Hee Oh;
Vivian Lam;
Krystal, Gerald;
Hoover, Shelley B.;
Raffeld, Mark;
Simpson, R. Mark;
Unni, Arun M.;
Lam, Wan L.;
Lam, Stephen;
Abraham, Ninan

Publication type:

Article

Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188881

By:

Elisia, Ingrid;
Lam, Vivian;
Hofs, Elyse;
Li, Michael Yu;
Hay, Mariah;
Cho, Brandon;
Brooks-Wilson, Angela;
Rosin, Miriam;
Bu, Luke;
Jia, William;
Krystal, Gerald

Publication type:

Article

Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 27, p. 5195, doi. 10.1002/ejoc.201200631

By:

Meimetis, Labros G.;
Nodwell, Matt;
Yang, Lu;
Wang, Xiaoxia;
Wu, Joyce;
Harwig, Curtis;
Stenton, Grant R.;
Mackenzie, Lloyd F.;
MacRury, Thomas;
Patrick, Brian O.;
Ming-Lum, Andrew;
Ong, Christopher J.;
Krystal, Gerald;
Mui, Alice L. -F.;
Andersen, Raymond J.

Publication type:

Article

CM Affi-Gel Blue chromatography of human urine: a simple one-step procedure for obtaining erythropoietin suitable for in vitro erythropoietic progenitor assays.

Published in:

British Journal of Haematology, 1984, v. 58, n. 3, p. 533, doi. 10.1111/j.1365-2141.1984.tb04001.x

By:

Krystal, Gerald;
Eaves, Connie J.;
Eaves, Allen C.

Publication type:

Article

Apigenin Increases SHIP-1 Expression, Promotes Tumoricidal Macrophages and Anti-Tumor Immune Responses in Murine Pancreatic Cancer.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3631, doi. 10.3390/cancers12123631

By:

Villalobos-Ayala, Krystal;
Ortiz Rivera, Ivannie;
Alvarez, Ciara;
Husain, Kazim;
DeLoach, DeVon;
Krystal, Gerald;
Hibbs, Margaret L.;
Jiang, Kun;
Ghansah, Tomar

Publication type:

Article

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts.

Published in:

Nature Medicine, 2002, v. 8, n. 9, p. 943, doi. 10.1038/nm752

By:

Takeshita, Sunao;
Namba, Noriyuki;
Zhao, Jenny J.;
Jiang, Yebin;
Genant, Harry K.;
Silva, Matthew J.;
Brodt, Michael D.;
Helgason, Cheryl D.;
Kalesnikoff, Janet;
Rauh, Michael J.;
Humphries, R. Keith;
Krystal, Gerald;
Teitelbaum, Steven L.;
Ross, F. Patrick

Publication type:

Article

Serum inhibits the immunosuppressive function of myeloid-derived suppressor cells isolated from 4T1 tumor-bearing mice.

Published in:

Cancer Immunology, Immunotherapy, 2012, v. 61, n. 5, p. 643, doi. 10.1007/s00262-011-1125-0

By:

Hamilton, Melisa;
Banáth, Judit;
Lam, Vivian;
LePard, Nancy;
Krystal, Gerald;
Bennewith, Kevin

Publication type:

Article

A Low Carbohydrate, High Protein Diet May Extend Your Life and Reduce Your Chances of Getting Cancer.

Published in:

UBC Medical Journal, 2012, v. 3, n. 2, p. 11

By:

Ho, Victor W.;
Krystal, Gerald

Publication type:

Article

Erythropoiesis after withdrawal of enalapril in post-transplant erythrocytosis.

Published in:

Kidney International, 1994, v. 46, n. 5, p. 1397, doi. 10.1038/ki.1994.411

By:

Julian, Bruce A.;
Gaston, Robert S.;
Barker, Catherine V.;
Krystal, Gerald;
Diethelm, Arnold G.;
Curtis, John J.

Publication type:

Article

A ketogenic diet rich in fish oil is superior to other fats in preventing NNK-induced lung cancer in A/J mice.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55167-6

By:

Elisia, Ingrid;
Yeung, Michelle;
Kowalski, Sara;
Shyp, Taras;
Tee, Jason;
Hollman, Serena;
Wong, Amy;
King, Janette;
Dyer, Roger;
Sorensen, Poul H.;
Krystal, Gerald

Publication type:

Article

Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer.

Published in:

Cancers, 2022, v. 14, n. 15, p. 3613, doi. 10.3390/cancers14153613

By:

Husain, Kazim;
Villalobos-Ayala, Krystal;
Laverde, Valentina;
Vazquez, Oscar A.;
Miller, Bradley;
Kazim, Samra;
Blanck, George;
Hibbs, Margaret L.;
Krystal, Gerald;
Elhussin, Isra;
Mori, Joakin;
Yates, Clayton;
Ghansah, Tomar

Publication type:

Article

Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial.

Published in:

PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0296523

By:

Buga, Alex;
Harper, David G.;
Sapper, Teryn N.;
Hyde, Parker N.;
Fell, Brandon;
Dickerson, Ryan;
Stoner, Justen T.;
Kackley, Madison L.;
Crabtree, Christopher D.;
Decker, Drew D.;
Robinson, Bradley T.;
Krystal, Gerald;
Binzel, Katherine;
Lustberg, Maryam B.;
Volek, Jeff S.

Publication type:

Article

Cardiac hypertrophy in the Dahl rat is associated with increased tyrosine phosphorylation of several cytosolic proteins, including a 120 kDa protein*.

Published in:

American Journal of Hypertension, 1996, v. 9, n. 3, p. 230, doi. 10.1016/0895-7061(95)00382-7

By:

Rabkin, Simon W.;
Damen, Jacqueline E.;
Goutsouliak, Valeri;
Krystal, Gerald

Publication type:

Article

The effect of smoking on chronic inflammation, immune function and blood cell composition.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76556-7

By:

Elisia, Ingrid;
Lam, Vivian;
Cho, Brandon;
Hay, Mariah;
Li, Michael Yu;
Yeung, Michelle;
Bu, Luke;
Jia, William;
Norton, Nancy;
Lam, Stephen;
Krystal, Gerald

Publication type:

Article

Development of a novel human triculture model of non-alcoholic fatty liver disease and identification of berberine as ameliorating steatosis, oxidative stress and fibrosis.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1234300

By:

Rafiei, Hossein;
Yeung, Michelle;
Kowalski, Sara;
Krystal, Gerald;
Elisia, Ingrid

Publication type:

Article

Activin/TGF-β induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

Published in:

Nature Cell Biology, 2002, v. 4, n. 12, p. 963, doi. 10.1038/ncb885

By:

Valderrama-Carvajal, Hector;
Cocolakis, Eftihia;
Lacerte, Annie;
Lee, Eun-Hye;
Krystal, Gerald;
Ali, Suhad;
Lebrun, Jean-Jacques

Publication type:

Article

SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021893

By:

Antignano, Frann;
Hamilton, Melisa;
Patterson, Scott;
Ho, Victor;
Cohen, Carla;
Levings, Megan K.;
Krystal, Gerald

Publication type:

Article

THE ROLE OF ERYTHROPOIETIN RECEPTOR TYROSINE PHOSPHORYLATION IN ERYTHROPOIETIN-INDUCED PROLIFERATION.

Published in:

Leukemia (08876924), 1997, v. 11, p. 423

By:

DAMEN, Jacqueline E.;
Ling LIU;
WAKAO, Hiroshi;
MIYAJIMA, Atsushi;
ROSTEN, Patricia;
JEFFERSON, Anne B.;
MAJERUS, Philip W.;
KROSL, Jana;
HUMPHRIES, R. Keith;
KRYSTAL, Gerald

Publication type:

Article

low-carbohydrate diet containing soy protein and fish oil reduces breast but not prostate cancer in C3(1)/Tag mice.

Published in:

Carcinogenesis, 2022, v. 43, n. 2, p. 115, doi. 10.1093/carcin/bgab106

By:

Elisia, Ingrid;
Yeung, Michelle;
Wong, Jennifer;
Kowalski, Sara;
Larsen, Meegan;
Shyp, Taras;
Sorensen, Poul H;
Krystal, Gerald

Publication type:

Article

Low carbohydrate diets containing soy protein and fish oil slow the growth of established NNK-induced lung tumors.

Published in:

Carcinogenesis, 2020, v. 41, n. 8, p. 1083, doi. 10.1093/carcin/bgaa028

By:

Elisia, Ingrid;
Hay, Mariah;
Cho, Brandon;
Yeung, Michelle;
Kowalski, Sara;
Wong, Jennifer;
Lam, Vivian;
Larsen, Meegan;
Krystal, Gerald

Publication type:

Article

effect of diet and exercise on tobacco carcinogen-induced lung cancer.

Published in:

Carcinogenesis, 2019, v. 40, n. 3, p. 448, doi. 10.1093/carcin/bgz060

By:

Elisia, Ingrid;
Cho, Brandon;
Hay, Mariah;
Li, Michael Yu;
Hofs, Elyse;
Lam, Vivian;
Dyer, Roger A;
Lum, Julian;
Krystal, Gerald

Publication type:

Article

A low carbohydrate, high protein diet combined with celecoxib markedly reduces metastasis.

Published in:

Carcinogenesis, 2014, v. 35, n. 10, p. 2291, doi. 10.1093/carcin/bgu147

By:

Ho, Victor W.;
Hamilton, Melisa J.;
Dang, Ngoc-Ha Thi;
Hsu, Brian E.;
Adomat, Hans H.;
Guns, Emma S.;
Weljie, Aalim;
Samudio, Ismael;
Bennewith, Kevin L.;
Krystal, Gerald

Publication type:

Article

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases.

Published in:

European Journal of Immunology, 1998, v. 28, n. 1, p. 264, doi. 10.1002/(SICI)1521-4141(199801)28:01<264::AID-IMMU264>3.0.CO;2-O

By:

Le Dréan, Eric;
Vély, Frédéric;
Olcese, Lucia;
Cambiaggi, Anna;
Guia, Sophie;
Krystal, Gerald;
Gervois, Nadine;
Moretta, Alessandro;
Jotereau, Francine;
Vivier, Eric

Publication type:

Article

Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs.

Published in:

European Journal of Immunology, 1997, v. 27, n. 8, p. 1994, doi. 10.1002/eji.1830270825

By:

Vély, Frédéric;
Olivero, Sylvain;
Olcese, Lucia;
Moretta, Alessandro;
Damen, Jacqueline E.;
Liu, Ling;
Krystal, Gerald;
Cambier, John C.;
Daëron, Marc;
Vivier, Eric

Publication type:

Article

Works by Krystal, Gerald

Saponins in soy reduce NNK-induced lung cancer by increasing plasma isoflavone levels.

Phosphatidylinositol 3,4,5-trisphosphate regulates Ca<sup>2+</sup> entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity.

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.

All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E<sub>2</sub> in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages.

DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis.

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development.

Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges.

Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol.

CM Affi-Gel Blue chromatography of human urine: a simple one-step procedure for obtaining erythropoietin suitable for in vitro erythropoietic progenitor assays.

Apigenin Increases SHIP-1 Expression, Promotes Tumoricidal Macrophages and Anti-Tumor Immune Responses in Murine Pancreatic Cancer.

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts.

Serum inhibits the immunosuppressive function of myeloid-derived suppressor cells isolated from 4T1 tumor-bearing mice.

A Low Carbohydrate, High Protein Diet May Extend Your Life and Reduce Your Chances of Getting Cancer.

Erythropoiesis after withdrawal of enalapril in post-transplant erythrocytosis.

A ketogenic diet rich in fish oil is superior to other fats in preventing NNK-induced lung cancer in A/J mice.

Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer.

Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial.

Cardiac hypertrophy in the Dahl rat is associated with increased tyrosine phosphorylation of several cytosolic proteins, including a 120 kDa protein<sup>*</sup>.

The effect of smoking on chronic inflammation, immune function and blood cell composition.

Development of a novel human triculture model of non-alcoholic fatty liver disease and identification of berberine as ameliorating steatosis, oxidative stress and fibrosis.

Activin/TGF-β induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism.

THE ROLE OF ERYTHROPOIETIN RECEPTOR TYROSINE PHOSPHORYLATION IN ERYTHROPOIETIN-INDUCED PROLIFERATION.

low-carbohydrate diet containing soy protein and fish oil reduces breast but not prostate cancer in C3(1)/Tag mice.

Low carbohydrate diets containing soy protein and fish oil slow the growth of established NNK-induced lung tumors.

effect of diet and exercise on tobacco carcinogen-induced lung cancer.

A low carbohydrate, high protein diet combined with celecoxib markedly reduces metastasis.

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases.

Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs.