Works by Kruglyak, Leonid

Results: 92

A Joint Analysis of Asthma Affection Status and IgE Levels in Multiple Data Sets Collected for Asthma.

Published in:

Genetic Epidemiology, 2001, v. 21, p. S148, doi. 10.1002/gepi.2001.21.s1.s148

By:

Markianos, Kyriacos;
Carlson, Scott;
Gibbs, Mark;
Kruglyak, Leonid

Publication type:

Article

An analysis of strategies for discovery of single-nucleotide polymorphisms.

Published in:

Genetic Epidemiology, 2000, v. 19, n. S1, p. S29, doi. 10.1002/1098-2272(2000)19:1+<::AID-GEPI5>3.0.CO;2-P

By:

Eberle, Michael A.;
Kruglyak, Leonid

Publication type:

Article

Sib-pair collection strategies for complex diseases.

Published in:

Genetic Epidemiology, 1998, v. 15, n. 4, p. 317, doi. 10.1002/(SICI)1098-2272(1998)15:4<317::AID-GEPI1>3.0.CO;2-#

By:

McCarthy, Mark I.;
Kruglyak, Leonid;
Lander, Eric S.

Publication type:

Article

Do multiple data sets provide support for a bipolar illness susceptibility locus on chromosome 18?

Published in:

Genetic Epidemiology, 1997, v. 14, n. 6, p. 599, doi. 10.1002/(SICI)1098-2272(1997)14:6<599::AID-GEPI8>3.0.CO;2-V

By:

Daly, Mark;
Kirby, Andrew;
Kruglyak, Leonid

Publication type:

Article

A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays.

Published in:

Bioinformatics, 2009, v. 25, n. 13, p. 1609, doi. 10.1093/bioinformatics/btp275

By:

Zia Khan;
Joshua S. Bloom;
Leonid Kruglyak;
Mona Singh

Publication type:

Article

The role of regulatory variation in complex traits and disease.

Published in:

Nature Reviews Genetics, 2015, v. 16, n. 4, p. 197, doi. 10.1038/nrg3891

By:

Albert, Frank W.;
Kruglyak, Leonid

Publication type:

Article

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity.

Published in:

Nature Genetics, 2012, v. 44, n. 3, p. 285, doi. 10.1038/ng.1050

By:

Andersen, Erik C;
Gerke, Justin P;
Shapiro, Joshua A;
Crissman, Jonathan R;
Ghosh, Rajarshi;
Bloom, Joshua S;
Félix, Marie-Anne;
Kruglyak, Leonid

Publication type:

Article

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks.

Published in:

Nature Genetics, 2008, v. 40, n. 7, p. 854, doi. 10.1038/ng.167

By:

Jun Zhu;
Bin Zhang;
Smith, Erin N.;
Drees, Becky;
Brem, Rachel B.;
Kruglyak, Leonid;
Bumgarner, Roger E.;
Schadt, Eric E.

Publication type:

Article

Genetic basis of proteome variation in yeast.

Published in:

Nature Genetics, 2007, v. 39, n. 11, p. 1369, doi. 10.1038/ng.2007.22

By:

Foss, Eric J.;
Radulovic, Dragan;
Shaffer, Scott A.;
Ruderfer, Douglas M.;
Bedalov, Antonio;
Goodlett, David R.;
Kruglyak, Leonid

Publication type:

Article

Genetic basis of individual differences in the response to small-molecule drugs in yeast.

Published in:

Nature Genetics, 2007, v. 39, n. 4, p. 496, doi. 10.1038/ng1991

By:

Perlstein, Ethan O.;
Ruderfer, Douglas M.;
Roberts, David C.;
Schreiber, Stuart L.;
Kruglyak, Leonid

Publication type:

Article

Population genomic analysis of outcrossing and recombination in yeast.

Published in:

Nature Genetics, 2006, v. 38, n. 9, p. 1077, doi. 10.1038/ng1859

By:

Ruderfer, Douglas M.;
Pratt, Stephen C.;
Seidel, Hannah S.;
Kruglyak, Leonid

Publication type:

Article

Power tools for human genetics.

Published in:

Nature Genetics, 2005, v. 37, n. 12, p. 1299, doi. 10.1038/ng1205-1299

By:

Kruglyak, Leonid

Publication type:

Article

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors.

Published in:

Nature Genetics, 2003, v. 35, n. 1, p. 57, doi. 10.1038/ng1222

By:

Yvert, Gaël;
Brem, Rachel B.;
Whittle, Jacqueline;
Akey, Joshua M.;
Foss, Eric;
Smith, Erin N.;
Mackelprang, Rachel;
Kruglyak, Leonid

Publication type:

Article

Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans.

Published in:

Nature Genetics, 2003, v. 33, n. 4, p. 518, doi. 10.1038/ng1128

By:

Carlson, Christopher S.;
Eberle, Michael A.;
Rieder, Mark J.;
Smith, Joshua D.;
Kruglyak, Leonid;
Nickerson, Deborah A.

Publication type:

Article

Variation is the spice of life.

Published in:

Nature Genetics, 2001, v. 27, n. 3, p. 234, doi. 10.1038/85776

By:

Kruglyak, Leonid;
Nickerson, Deborah A

Publication type:

Article

Guilt by association.

Published in:

Nature Genetics, 2000, v. 26, n. 2, p. 135, doi. 10.1038/79839

By:

Altshuler, David;
Daly, Mark;
Kruglyak, Leonid

Publication type:

Article

Sampling SNPs.

Published in:

Nature Genetics, 2000, v. 26, n. 1, p. 13, doi. 10.1038/79113

By:

Yang, Zhiyong;
Ka-Shu Wong, Gane;
Eberle, Michael A.;
Kibukawa, Miho;
Passey, Douglas A.;
Hughes, William R.;
Kruglyak, Leonid;
Yu, Jun

Publication type:

Article

Single-nucleotide polymorphisms in human genetics.

Published in:

1999

By:

Kruglyak, Leonid

Publication type:

Abstract

Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.

Published in:

BMC Genomics, 2009, v. 10, p. 1, doi. 10.1186/1471-2164-10-221

By:

Bloom, Joshua S.;
Khan, Zia;
Kruglyak, Leonid;
Singh, Mona;
Caudy, Amy A.

Publication type:

Article

A Wild C. Elegans Strain Has Enhanced Epithelial Immunity to a Natural Microsporidian Parasite.

Published in:

PLoS Pathogens, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.ppat.1004583

By:

Balla, Keir M.;
Andersen, Erik C.;
Kruglyak, Leonid;
Troemel, Emily R.

Publication type:

Article

Lower Severe Acute Respiratory Syndrome Coronavirus 2 Viral Shedding Following Coronavirus Disease 2019 Vaccination Among Healthcare Workers in Los Angeles, California.

Published in:

2021

By:

Adamson, Paul C;
Pfeffer, Michael A;
Arboleda, Valerie A;
Garner, Omai B;
Maurice, Annabelle de St;
Bredow, Benjamin von;
Flint, Jonathan;
Kruglyak, Leonid;
Currier, Judith S

Publication type:

Case Study

Whole-organism eQTL mapping at cellular resolution with single-cell sequencing.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65857

By:

Ben-David, Eyal;
Boocock, James;
Guo, Longhua;
Zdraljevic, Stefan;
Bloom, Joshua S.;
Kruglyak, Leonid

Publication type:

Article

Using Expression and Genotype to Predict Drug Response in Yeast.

Published in:

PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0006907

By:

Ruderfer, Douglas M.;
Roberts, David C.;
Schreiber, Stuart L.;
Perlstein, Ethan O.;
Kruglyak, Leonid

Publication type:

Article

Comparative Developmental Expression Profiling of Two C. elegans Isolates.

Published in:

PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0004055

By:

Capra, Emily J.;
Skrovanek, Sonja M.;
Kruglyak, Leonid

Publication type:

Article

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans.

Published in:

BMC Biology, 2012, v. 10, n. 1, p. 85, doi. 10.1186/1741-7007-10-85

By:

Ghosh, Rajarshi;
Mohammadi, Aylia;
Kruglyak, Leonid;
Ryu, William S.

Publication type:

Article

Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.

Published in:

Molecular Systems Biology, 2012, v. 8, n. 1, p. 602, doi. 10.1038/msb.2012.34

By:

Khan, Zia;
Bloom, Joshua S;
Amini, Sasan;
Singh, Mona;
Perlman, David H;
Caudy, Amy A;
Kruglyak, Leonid

Publication type:

Article

Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos.

Published in:

PLoS Genetics, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.pgen.1009580

By:

Guo, Longhua;
Bloom, Joshua;
Sykes, Steve;
Huang, Elaine;
Kashif, Zain;
Pham, Elise;
Ho, Katarina;
Alcaraz, Ana;
Xiao, Xinshu Grace;
Duarte-Vogel, Sandra;
Kruglyak, Leonid

Publication type:

Article

The Genetic Basis of Mutation Rate Variation in Yeast.

Published in:

Genetics, 2019, v. 211, n. 2, p. 731, doi. 10.1534/genetics.118.301609

By:

Liangke Gou;
Bloom, Joshua S.;
Kruglyak, Leonid

Publication type:

Article

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.

Published in:

Genetics, 2016, v. 204, n. 1, p. 371, doi. 10.1534/genetics.116.191148

By:

Cook, Daniel E.;
Zdraljevic, Stefan;
Tanny, Robyn E.;
Seo, Beomseok;
Riccardi, David D.;
Noble, Luke M.;
Rockman, Matthew V.;
Alkema, Mark J.;
Braendle, Christian;
Kammenga, Jan E.;
Wang, John;
Kruglyak, Leonid;
Félix, Marie-Anne;
Lee, Junho;
Andersen, Erik C.

Publication type:

Article

Complex Traits and Simple Systems: An Interview with Leonid Kruglyak.

Published in:

2016

By:

Kruglyak, Leonid

Publication type:

Interview

Genetics of Intraspecies Variation in Avoidance Behavior Induced by a Thermal Stimulus in Caenorhabditis elegans.

Published in:

Genetics, 2015, v. 200, n. 4, p. 1327, doi. 10.1534/genetics.115.178491

By:

Ghosh, Rajarshi;
Bloom, Joshua S.;
Mohammadi, Aylia;
Schumer, Molly E.;
Andolfatto, Peter;
Ryu, William;
Kruglyak, Leonid

Publication type:

Article

Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856.

Published in:

Genetics, 2015, v. 200, n. 3, p. 975, doi. 10.1534/genetics.115.175950

By:

Thompson, Owen A.;
Basten Snoek, L.;
Nijveen, Harm;
Sterken, Mark G.;
Volkers, Rita J. M.;
Brenchley, Rachel;
van't Hof, Arjen;
Bevers, Roel P. J.;
Cossins, Andrew R.;
Yanai, Itai;
Hajnal, Alex;
Schmid, Tobias;
Perkins, Jaryn D.;
Spencer, David;
Kruglyak, Leonid;
Andersen, Erik C.;
Moerman, Donald G.;
Hillier, LaDeana W.;
Kammenga, Jan E.;
Waterston, Robert H.

Publication type:

Article

Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression.

Published in:

Genetics, 2014, v. 198, n. 3, p. 1277, doi. 10.1534/genetics.114.168948

By:

Heyne, Henrike O.;
Lautenschläger, Susann;
Nelson, Ronald;
Besnier, François;
Rotival, Maxime;
Cagan, Alexander;
Kozhemyakina, Rimma;
Plyusnina, Irina Z.;
Trut, Lyudmila;
Carlborg, Örjan;
Petretto, Enrico;
Kruglyak, Leonid;
Pääbo, Svante;
Schöneberg, Torsten;
Albert, Frank W.

Publication type:

Article

More Than the Sum of Its Parts: A Complex Epistatic Network Underlies Natural Variation in Thermal Preference Behavior in Caenorhabditis elegans.

Published in:

Genetics, 2012, v. 192, n. 4, p. 1533, doi. 10.1534/genetics.112.142877

By:

Gaertner, Bryn E.;
Parmenter, Michelle D.;
Rockman, Matthew V.;
Kruglyak, Leonid;
Phillips, Patrick C.

Publication type:

Article

Breeding Designs for Recombinant Inbred Advanced Intercross Lines.

Published in:

Genetics, 2008, v. 179, n. 2, p. 1069, doi. 10.1534/genetics.107.083873

By:

Rockman, Matthew V.;
Kruglyak, Leonid

Publication type:

Article

Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95566

By:

Boocock, James;
Alexander, Noah;
Alamo Tapia, Leslie;
Walter-McNeill, Laura;
Patel, Shivani Prashant;
Munugala, Chetan;
Bloom, Joshua S.;
Kruglyak, Leonid

Publication type:

Article

Genetic Control of Serum IgE Levels and Asthma: Linkage and Linkage Disequilibrium Studies in an Isolated Population.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 12, p. 2069, doi. 10.1093/hmg/6.12.2069

By:

Laitinen, Tarja;
Kauppi, Paula;
Ignatius, Jaakko;
Ruotsalainen, Tarja;
Daly, Mark J.;
Kääriäinen, Helena;
Kruglyak, Leonid;
Laitinen, Hannu;
de la Chapelle, Albert;
Lander, Eric S.;
Laitinen, Lauri A.;
Kere, Juha

Publication type:

Article

Cause and express.

Published in:

Nature Biotechnology, 2009, v. 27, n. 6, p. 544, doi. 10.1038/nbt0609-544

By:

Kruglyak, Leonid;
Storey, John D.

Publication type:

Article

Genetic Variation Shapes Protein Networks Mainly through Non-transcriptional Mechanisms.

Published in:

PLoS Biology, 2011, v. 9, n. 9, p. 1, doi. 10.1371/journal.pbio.1001144

By:

Foss, Eric J.;
Radulovic, Dragan;
Shaffer, Scott A.;
Goodlett, David R.;
Kruglyak, Leonid;
Bedalov, Antonio

Publication type:

Article

A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in C. elegans.

Published in:

PLoS Biology, 2011, v. 9, n. 7, p. 1, doi. 10.1371/journal.pbio.1001115

By:

Seidel, Hannah S.;
Ailion, Michael;
Li, Jialing;
van Oudenaarden, Alexander;
Rockman, Matthew V.;
Kruglyak, Leonid

Publication type:

Article

GeneEnvironment Interaction in Yeast Gene Expression.

Published in:

PLoS Biology, 2008, v. 6, n. 4, p. e83, doi. 10.1371/journal.pbio.0060083

By:

Smith, Erin N.;
Kruglyak, Leonid

Publication type:

Article

Multiple Locus Linkage Analysis of Genomewide Expression in Yeast.

Published in:

PLoS Biology, 2005, v. 3, n. 8, p. 1380, doi. 10.1371/journal.pbio.0030267

By:

Storey, John D.;
Akey, Joshua M.;
Kruglyak, Leonid

Publication type:

Article

Multiple Locus Linkage Analysis of Genomewide Expression in Yeast.

Published in:

PLoS Biology, 2005, v. 3, n. 7, p. 1, doi. 10.1371/journal.pbio.0030267

By:

Storey, John D;
Akey, Joshua M;
Kruglyak, Leonid

Publication type:

Article

Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes.

Published in:

PLoS Biology, 2004, v. 2, n. 10, p. 1591, doi. 10.1371/journal.pbio.0020286

By:

Akeyi, Joshua M.;
Eberle, Michael A.;
Rieder, Mark J.;
Carison, Christopher S.;
Shriver, Mark D.;
Nickerson, Deborah A.;
Kruglyak, Leonid

Publication type:

Article

Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes.

Published in:

PLoS Biology, 2004, v. 2, n. 9, p. 1, doi. 10.1371/journal.pbio.0020286

By:

Akey, Joshua M;
Eberle, Michael A;
Rieder, Mark J;
Carlson, Christopher S;
Shriver, Mark D;
Nickerson, Deborah A;
Kruglyak, Leonid

Publication type:

Article

The road to genome-wide association studies.

Published in:

Nature Reviews Genetics, 2008, v. 9, n. 4, p. 314, doi. 10.1038/nrg2316

By:

Kruglyak, Leonid

Publication type:

Article

Genetics of global gene expression.

Published in:

Nature Reviews Genetics, 2006, v. 7, n. 11, p. 862, doi. 10.1038/nrg1964

By:

Rockman, Matthew V.;
Kruglyak, Leonid

Publication type:

Article

PATTERNS OF LINKAGE DISEQUILIBRIUM IN THE HUMAN GENOME.

Published in:

Nature Reviews Genetics, 2002, v. 3, n. 4, p. 299, doi. 10.1038/nrg777

By:

Ardlie, Kristin G.;
Kruglyak, Leonid;
Seielstad, Mark

Publication type:

Article

Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression.

Published in:

Microbial Cell Factories, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12934-022-01849-7

By:

Brandenberg, Oliver F.;
Schubert, Olga T.;
Kruglyak, Leonid

Publication type:

Article

Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression.

Published in:

Microbial Cell Factories, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12934-022-01849-7

By:

Brandenberg, Oliver F.;
Schubert, Olga T.;
Kruglyak, Leonid

Publication type:

Article