Works by Kozin, Sergey

Results: 42

Zinc-induced heterodimer formation between metal-binding domains of intact and naturally modified amyloid-beta species: implication to amyloid seeding in Alzheimer’s disease?

Published in:

Journal of Biomolecular Structure & Dynamics, 2016, v. 34, n. 11, p. 2317, doi. 10.1080/07391102.2015.1113890

By:

Mezentsev, Yuri V.;
Medvedev, Alexei E.;
Kechko, Olga I.;
Makarov, Alexander A.;
Ivanov, Alexis S.;
Mantsyzov, Alexey B.;
Kozin, Sergey A.

Publication type:

Article

The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis.

Published in:

Nature, 2004, v. 428, n. 6980, p. 328, doi. 10.1038/nature02329

By:

Garkavtsev, Igor;
Kozin, Sergey V.;
Chernova, Olga;
Lei Xu;
Winkler, Frank;
Brown, Edward;
Barnett, Gene H.;
Jain, Rakesh K.

Publication type:

Article

Electrochemical Analysis in Studying β-Amyloid Aggregation.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 1, p. S88, doi. 10.1134/S0006297923140067

By:

Suprun, Elena V.;
Radko, Sergey P.;
Kozin, Sergey A.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

Role of Interaction between Zinc and Amyloid Beta in Pathogenesis of Alzheimer’s Disease.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 1, p. S75, doi. 10.1134/S0006297923140055

By:

Kozin, Sergey A.

Publication type:

Article

Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity.

Published in:

Cells (2073-4409), 2019, v. 8, n. 8, p. 771, doi. 10.3390/cells8080771

By:

Barykin, Evgeny P.;
Garifulina, Alexandra I.;
Kruykova, Elena V.;
Spirova, Ekaterina N.;
Anashkina, Anastasia A.;
Adzhubei, Alexei A.;
Shelukhina, Irina V.;
Kasheverov, Igor E.;
Mitkevich, Vladimir A.;
Kozin, Sergey A.;
Hollmann, Michael;
Tsetlin, Victor I.;
Makarov, Alexander A.

Publication type:

Article

Development of Peptide Biopharmaceuticals in Russia.

Published in:

Pharmaceutics, 2022, v. 14, n. 4, p. N.PAG, doi. 10.3390/pharmaceutics14040716

By:

Deigin, Vladislav I.;
Poluektova, Elena A.;
Beniashvili, Allan G.;
Kozin, Sergey A.;
Poluektov, Yuri M.

Publication type:

Article

Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice.

Published in:

Neurotoxicity Research, 2016, v. 29, n. 4, p. 551, doi. 10.1007/s12640-016-9603-y

By:

Kulikova, Alexandra;
Cheglakov, Ivan;
Kukharsky, Michail;
Ovchinnikov, Ruslan;
Kozin, Sergey;
Makarov, Alexander

Publication type:

Article

Switching On/Off Amyloid Plaque Formation in Transgenic Animal Models of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 72, doi. 10.3390/ijms25010072

By:

Kozin, Sergey A.;
Kechko, Olga I.;
Adzhubei, Alexei A.;
Makarov, Alexander A.;
Mitkevich, Vladimir A.

Publication type:

Article

Molecular Mechanism of Zinc-Dependent Oligomerization of Alzheimer's Amyloid-β with Taiwan (D7H) Mutation.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 14, p. 11241, doi. 10.3390/ijms241411241

By:

Kechko, Olga I.;
Adzhubei, Alexei A.;
Tolstova, Anna P.;
Indeykina, Maria I.;
Popov, Igor A.;
Zhokhov, Sergey S.;
Gnuchev, Nikolay V.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.;
Kozin, Sergey A.

Publication type:

Article

Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6272, doi. 10.3390/ijms21176272

By:

Barykin, Evgeny P.;
Garifulina, Aleksandra I.;
Tolstova, Anna P.;
Anashkina, Anastasia A.;
Adzhubei, Alexei A.;
Mezentsev, Yuri V.;
Shelukhina, Irina V.;
Kozin, Sergey A.;
Tsetlin, Victor I.;
Makarov, Alexander A.

Publication type:

Article

The Effects of Endogenous Non-Peptide Molecule Isatin and Hydrogen Peroxide on Proteomic Profiling of Rat Brain Amyloid-β Binding Proteins: Relevance to Alzheimer's Disease?

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 1, p. 476, doi. 10.3390/ijms16010476

By:

Medvedev, Alexei E.;
Buneeva, Olga A.;
Kopylov, Arthur T.;
Gnedenko, Oksana V.;
Medvedeva, Marina V.;
Kozin, Sergey A.;
Ivanov, Alexis S.;
Zgoda, Victor G.;
Makarov, Alexander A.

Publication type:

Article

Protein interactomics based on direct molecular fishing on paramagnetic particles: Practical realization and further SPR validation.

Published in:

Proteomics, 2014, v. 14, n. 20, p. 2261, doi. 10.1002/pmic.201400117

By:

Ivanov, Alexis S.;
Medvedev, Alexei;
Ershov, Pavel;
Molnar, Andrey;
Mezentsev, Yury;
Yablokov, Evgeny;
Kaluzhsky, Leonid;
Gnedenko, Oksana;
Buneeva, Olga;
Haidukevich, Irina;
Sergeev, Gennadiy;
Lushchyk, Aliaksandr;
Yantsevich, Alexey;
Medvedeva, Marina;
Kozin, Sergey;
Popov, Igor;
Novikova, Svetlana;
Zgoda, Victor;
Gilep, Andrey;
Usanov, Sergey

Publication type:

Article

Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer’s Disease.

Published in:

Frontiers in Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnins.2018.00518

By:

Kozin, Sergey A.;
Barykin, Evgeny P.;
Telegin, Georgy B.;
Chernov, Alexander S.;
Adzhubei, Alexei A.;
Radko, Sergey P.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

Possible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein.

Published in:

Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 12, p. 3151, doi. 10.1110/ps.04745004

By:

Megy, Simon;
Bertho, Gildas;
Kozin, Sergey A.;
Debey, Pascale;
Hui Bon Hoa, Gaston;
Girault, Jean-Pierre

Publication type:

Article

The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Aβ-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2008, v. 22, n. 2, p. 231, doi. 10.1002/rcm.3357

By:

Toropygin, Ilya Yu.;
Kugaevskaya, Elena V.;
Mirgorodskaya, Olga A.;
Elisseeva, Yulia E.;
Kozmin, Yuri P.;
Popov, Igor A.;
Nikolaev, Eugene N.;
Makarov, Alexander A.;
Kozin, Sergey A.

Publication type:

Article

Zn-dependent β-amyloid Aggregation and its Reversal by the Tetrapeptide HAEE.

Published in:

Aging & Disease, 2023, v. 14, n. 2, p. 309, doi. 10.14336/AD.2022.0827

By:

Mitkevich, Vladimir A.;
Barykin, Evgeny P.;
Eremina, Svetlana;
Pani, Bibhusita;
Katkova-Zhukotskaya, Olga;
Polshakov, Vladimir I.;
Adzhubei, Alexei A.;
Kozin, Sergey A.;
Mironov, Alexander S.;
Makarov, Alexander A.;
Nudler, Evgeny

Publication type:

Article

Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-β Aggregation and Cytotoxicity.

Published in:

Aging & Disease, 2021, v. 12, n. 5, p. 1223, doi. 10.14336/AD.2020.1230

By:

Lazarev, Vladimir F.;
Tsolaki, Magda;
Mikhaylova, Elena R.;
Benken, Konstantin A.;
Shevtsov, Maxim A.;
Nikotina, Alina D.;
Lechpammer, Mirna;
Mitkevich, Vladimir A.;
Makarov, Alexander A.;
Moskalev, Alexey A.;
Kozin, Sergey A.;
Margulis, Boris A.;
Guzhova, Irina V.;
Nudler, Evgeny

Publication type:

Article

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition.

Published in:

Frontiers in Molecular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnmol.2018.00302

By:

Barykin, Evgeny P.;
Petrushanko, Irina Y.;
Kozin, Sergey A.;
Telegin, Georgy B.;
Chernov, Alexander S.;
Lopina, Olga D.;
Radko, Sergey P.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

CORRIGENDUM: Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer.

Published in:

Nature Medicine, 2004, v. 10, n. 6, p. 649, doi. 10.1038/nm0604-649c

By:

Willett, Christopher G;
Boucher, Yves;
di Tomaso, Emmanuelle;
Duda, Dan G;
Munn, Lance L;
Tong, Ricky T;
Chung, Daniel C;
Sahani, Dushyant V;
Kalva, Sanjeeva P;
Kozin, Sergey V;
Mino, Mari;
Cohen, Kenneth S;
Scadden, David T;
Hartford, Alan C;
Fischman, Alan J;
Clark, Jeffrey W;
Ryan, David P;
Zhu, Andrew X;
Blaszkowsky, Lawrence S;
Chen, Helen X

Publication type:

Article

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer.

Published in:

Nature Medicine, 2004, v. 10, n. 2, p. 145, doi. 10.1038/nm988

By:

Willett, Christopher G.;
Boucher, Yves;
Di Tomaso, Emmanuelle;
Duda, Dan G.;
Munn, Lance L.;
Tong, Ricky T.;
Chung, Daniel C.;
Sahani, Dushyant V.;
Kalva, Sanjeeva P.;
Kozin, Sergey V.;
Man Mino, Sergey V.;
Cohen, Kenneth S.;
Scadden, David T.;
Hartford, Alan C.;
Fischman, Alan J.;
Clark, Jeffrey W.;
Ryan, David P.;
Zhu, Andrew X.;
Blaszkowsky, Lawrence S.;
Chen, Helen X.

Publication type:

Article

Isomerization of the Asp7 Residue Results in Zinc-Induced Oligomerization of Alzheimer's Disease Amyloid β(1-16) Peptide.

Published in:

ChemBioChem, 2008, v. 9, n. 10, p. 1564, doi. 10.1002/cbic.200700784

By:

Tsvetkov, Philipp O.;
Popov, Igor A.;
Nikolaev, Eugene N.;
Archakov, Alexander I.;
Makarov, Alexander A.;
Kozin, Sergey A.

Publication type:

Article

Mass spectrometric studies of the variety of beta‐amyloid proteoforms in Alzheimer's disease.

Published in:

Mass Spectrometry Reviews, 2025, v. 44, n. 1, p. 3, doi. 10.1002/mas.21775

By:

Zakharova, Natalia V.;
Kononikhin, Alexey S.;
Indeykina, Maria I.;
Bugrova, Anna E.;
Strelnikova, Polina;
Pekov, Stanislav;
Kozin, Sergey A.;
Popov, Igor A.;
Mitkevich, Vladimir;
Makarov, Alexander A.;
Nikolaev, Evgeny N.

Publication type:

Article

Is vasculogenesis crucial for the regrowth of irradiated tumours?

Published in:

2011

By:

Kozin, Sergey V.;
Duda, Dan G.;
Munn, Lance L.;
Jain, Rakesh K.

Publication type:

commentary

Pharmacokinetics and Molecular Modeling Indicate nAChRα4-Derived Peptide HAEE Goes through the Blood–Brain Barrier.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 6, p. 909, doi. 10.3390/biom11060909

By:

Zolotarev, Yurii A.;
Mitkevich, Vladimir A.;
Shram, Stanislav I.;
Adzhubei, Alexei A.;
Tolstova, Anna P.;
Talibov, Oleg B.;
Dadayan, Alexander K.;
Myasoyedov, Nikolai F.;
Makarov, Alexander A.;
Kozin, Sergey A.

Publication type:

Article

The English (H6R) Mutation of the Alzheimer's Disease Amyloid-β Peptide Modulates Its Zinc-Induced Aggregation.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 6, p. 961, doi. 10.3390/biom10060961

By:

Radko, Sergey P.;
Khmeleva, Svetlana A.;
Kaluzhny, Dmitry N.;
Kechko, Olga I.;
Kiseleva, Yana Y.;
Kozin, Sergey A.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.

Published in:

Nature Communications, 2013, v. 4, n. 10, p. 2516, doi. 10.1038/ncomms3516

By:

Chauhan, Vikash P.;
Martin, John D.;
Liu, Hao;
Lacorre, Delphine A.;
Jain, Saloni R.;
Kozin, Sergey V.;
Stylianopoulos, Triantafyllos;
Mousa, Ahmed S.;
Han, Xiaoxing;
Adstamongkonkul, Pichet;
Popović, Zoran;
Huang, Peigen;
Bawendi, Moungi G.;
Boucher, Yves;
Jain, Rakesh K.

Publication type:

Article

Insights into the Cardiotoxic Effects of Veratrum Lobelianum Alkaloids: Pilot Study.

Published in:

Toxins, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/toxins14070490

By:

Taldaev, Amir;
Terekhov, Roman P.;
Melnik, Elizaveta V.;
Belova, Maria V.;
Kozin, Sergey V.;
Nedorubov, Andrey A.;
Pomerantseva, Tatyana Ya.;
Ramenskaya, Galina V.

Publication type:

Article

Supermetallization of peptides and proteins during electrospray ionization.

Published in:

Journal of Mass Spectrometry, 2015, v. 50, n. 9, p. 1079, doi. 10.1002/jms.3622

By:

Kostyukevich, Yury;
Kononikhin, Alexey;
Popov, Igor;
Indeykina, Maria;
Kozin, Sergey A.;
Makarov, Alexander A.;
Nikolaev, Eugene

Publication type:

Article

Frontispiz: A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

Published in:

Angewandte Chemie, 2017, v. 129, n. 39, p. n/a, doi. 10.1002/ange.201783961

By:

Polshakov, Vladimir I.;
Mantsyzov, Alexey B.;
Kozin, Sergey A.;
Adzhubei, Alexei A.;
Zhokhov, Sergey S.;
van Beek, Wouter;
Kulikova, Alexandra A.;
Indeykina, Maria I.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

Published in:

Angewandte Chemie, 2017, v. 129, n. 39, p. 11896, doi. 10.1002/ange.201704615

By:

Polshakov, Vladimir I.;
Mantsyzov, Alexey B.;
Kozin, Sergey A.;
Adzhubei, Alexei A.;
Zhokhov, Sergey S.;
van Beek, Wouter;
Kulikova, Alexandra A.;
Indeykina, Maria I.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models.

Published in:

Cancers, 2023, v. 15, n. 4, p. 1021, doi. 10.3390/cancers15041021

By:

Gupta, Nisha;
Ochiai, Hiroki;
Hoshino, Yoshinori;
Klein, Sebastian;
Zustin, Jozef;
Ramjiawan, Rakesh R.;
Kitahara, Shuji;
Maimon, Nir;
Bazou, Despina;
Chiang, Sarah;
Li, Sen;
Schanne, Daniel H.;
Jain, Rakesh. K.;
Munn, Lance L.;
Huang, Peigen;
Kozin, Sergey V.;
Duda, Dan G.

Publication type:

Article

Perivascular nitric oxide gradients normalize tumor vasculature.

Published in:

Nature Medicine, 2008, v. 14, n. 3, p. 255, doi. 10.1038/nm1730

By:

Kashiwagi, Satoshi;
Tsukada, Kosuke;
Lei Xu;
Miyazaki, Junichi;
Kozin, Sergey V.;
Tyrrell, James A.;
Sessa, William C.;
Gerweck, Leo E.;
Jain, Rakesh K.;
Fukumura, Dai

Publication type:

Article

Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

Published in:

Frontiers in Genetics, 2017, p. 1, doi. 10.3389/fgene.2017.00058

By:

Barykin, Evgeny P.;
Mitkevich, Vladimir A.;
Kozin, Sergey A.;
Makarov, Alexander A.

Publication type:

Article

Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy.

Published in:

JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 4, p. 1, doi. 10.1093/jnci/djv017

By:

Ager, Eleanor I.;
Kozin, Sergey V.;
Kirkpatrick, Nathaniel D.;
Seano, Giorgio;
Kodack, David P.;
Askoxylakis, Vasileios;
Yuhui Huang;
Goel, Shom;
Snuderl, Matija;
Muzikansky, Alona;
Finkelstein, Dianne M.;
Dransfield, Daniel T.;
Devy, Laetitia;
Boucher, Yves;
Dai Fukumura;
Jain, Rakesh K.

Publication type:

Article

Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.

Published in:

2015

By:

Ager, Eleanor I;
Kozin, Sergey V;
Kirkpatrick, Nathaniel D;
Seano, Giorgio;
Kodack, David P;
Askoxylakis, Vasileios;
Huang, Yuhui;
Goel, Shom;
Snuderl, Matija;
Muzikansky, Alona;
Finkelstein, Dianne M;
Dransfield, Daniel T;
Devy, Laetitia;
Boucher, Yves;
Fukumura, Dai;
Jain, Rakesh K

Publication type:

journal article

Neovascularization After Irradiation: What is the Source of Newly Formed Vessels in Recurring Tumors?

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 12, p. 899, doi. 10.1093/jnci/djs239

By:

Kozin, Sergey V.;
Duda, Dan G.;
Munn, Lance L.;
Jain, Rakesh K.

Publication type:

Article

Frontispiece: A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 39, p. n/a, doi. 10.1002/anie.201783961

By:

Polshakov, Vladimir I.;
Mantsyzov, Alexey B.;
Kozin, Sergey A.;
Adzhubei, Alexei A.;
Zhokhov, Sergey S.;
van Beek, Wouter;
Kulikova, Alexandra A.;
Indeykina, Maria I.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 39, p. 11734, doi. 10.1002/anie.201704615

By:

Polshakov, Vladimir I.;
Mantsyzov, Alexey B.;
Kozin, Sergey A.;
Adzhubei, Alexei A.;
Zhokhov, Sergey S.;
van Beek, Wouter;
Kulikova, Alexandra A.;
Indeykina, Maria I.;
Mitkevich, Vladimir A.;
Makarov, Alexander A.

Publication type:

Article

Extracellular complex of beta‐amyloid with glyceraldehyde‐3‐phosphate dehydrogenase contributes to neurodegeneration in Alzheimer's disease: Molecular and cell biology/APP/Abeta/amyloid.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043347

By:

Kozin, Sergey A.;
Lazarev, Vladimir;
Tsolaki, Magda;
Mikhailova, Elena;
Benken, Konstantin;
Shevtsov, Maxim;
Nikotina, Alina;
Mitkevich, Vladimir;
Makarov, Alexander;
Margulis, Boris;
Guzhova, Irina

Publication type:

Article

Identification of α4β2 nAChR interaction site with Aβ<sub>42</sub> and development of tetrapeptide capable of breaking this interaction: Molecular and cell biology/receptors.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040936

By:

Barykin, Evgeny;
Garifulina, Alexandra;
Adzhubei, Alexei;
Shelukhina, Irina;
Kozin, Sergey A.;
Mitkevich, Vladimir;
Tsetlin, Victor;
Makarov, Alexander

Publication type:

Article

Zinc-induced dimers of chemically modified a β- are possible aggregation seeds.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P793, doi. 10.1016/j.jalz.2014.05.1542

By:

Kozin, Sergey A.;
Tsvetkov, Philippe;
Kulikova, Alexandra;
Indeikina, Maria;
Mezentsev, Yuri;
Istrate, Andrey;
Popov, Igor;
Ivanov, Alexis;
Polshakov, Vladimir;
Makarov, Alexander

Publication type:

Article

Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization.

Published in:

Scientific Reports, 2016, p. 21734, doi. 10.1038/srep21734

By:

Istrate, Andrey N.;
Kozin, Sergey A.;
Zhokhov, Sergey S.;
Mantsyzov, Alexey B.;
Kechko, Olga I.;
Pastore, Annalisa;
Makarov, Alexander A.;
Polshakov, Vladimir I.

Publication type:

Article