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Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2285, doi. 10.3390/ijms24032285
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Grishchenko, Maria V.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Y.;
- Serebryakova, Olga G.;
- Timokhina, Elena N.;
- Zhilina, Ekaterina F.;
- Shchegolkov, Evgeny V.;
- Ulitko, Mariya V.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Burgart, Yanina V.;
- Saloutin, Victor I.;
- Bachurin, Sergey O.;
- Richardson, Rudy J.
Publication type:
Article
Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13925, doi. 10.3390/ijms232213925
By:
- Bachurin, Sergey O.;
- Shevtsova, Elena F.;
- Makhaeva, Galina F.;
- Aksinenko, Alexey Yu.;
- Grigoriev, Vladimir V.;
- Goreva, Tatiana V.;
- Epishina, Tatiana A.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Rudakova, Elena V.;
- Vinogradova, Darya V.;
- Shevtsov, Pavel N.;
- Pushkareva, Elena A.;
- Dubova, Ludmila G.;
- Serkova, Tatiana P.;
- Veselov, Ivan M.;
- Fisenko, Vladimir P.;
- Richardson, Rudy J.
Publication type:
Article
Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease.
Published in:
ChemMedChem, 2022, v. 17, n. 10, p. 1, doi. 10.1002/cmdc.202200080
By:
- Grishchenko, Maria V.;
- Makhaeva, Galina F.;
- Burgart, Yanina V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Kovaleva, Nadezhda V.;
- Serebryakova, Olga G.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Y.;
- Zhilina, Ekaterina F.;
- Shchegolkov, Evgeny V.;
- Richardson, Rudy J.;
- Saloutin, Victor I.
Publication type:
Article
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.
Published in:
Scientific Reports, 2017, p. 45627, doi. 10.1038/srep45627
By:
- Bachurin, Sergey O.;
- Shevtsova, Elena F.;
- Makhaeva, Galina F.;
- Grigoriev, Vladimir V.;
- Boltneva, Natalia P.;
- Kovaleva, Nadezhda V.;
- Lushchekina, Sofya V.;
- Shevtsov, Pavel N.;
- Neganova, Margarita E.;
- Redkozubova, Olga M.;
- Bovina, Elena V.;
- Gabrelyan, Alexey V.;
- Fisenko, Vladimir P.;
- Sokolov, Vladimir B.;
- Aksinenko, Alexey Yu;
- Echeverria, Valentina;
- Barreto, George E.;
- Aliev, Gjumrakch
Publication type:
Article
New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
Published in:
Biomolecules (2218-273X), 2022, v. 12, n. 11, p. 1551, doi. 10.3390/biom12111551
By:
- Elkina, Natalia A.;
- Grishchenko, Maria V.;
- Shchegolkov, Evgeny V.;
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Y.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Zhilina, Ekaterina F.;
- Perminova, Anastasiya N.;
- Lapshin, Luka S.;
- Burgart, Yanina V.;
- Saloutin, Victor I.;
- Richardson, Rudy J.
Publication type:
Article
Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System.
Published in:
Biomolecules (2218-273X), 2020, v. 10, n. 2, p. 283, doi. 10.3390/biom10020283
By:
- Akimov, Mikhail G.;
- Kudryavtsev, Denis S.;
- Kryukova, Elena V.;
- Fomina-Ageeva, Elena V.;
- Zakharov, Stanislav S.;
- Gretskaya, Natalia M.;
- Zinchenko, Galina N.;
- Serkov, Igor V.;
- Makhaeva, Galina F.;
- Boltneva, Natalia P.;
- Kovaleva, Nadezhda V.;
- Serebryakova, Olga G.;
- Lushchekina, Sofya V.;
- Palikov, Victor A.;
- Palikova, Yulia;
- Dyachenko, Igor A.;
- Kasheverov, Igor E.;
- Tsetlin, Victor I.;
- Bezuglov, Vladimir V.
Publication type:
Article
Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block β‐amyloid aggregation.
Published in:
Archiv der Pharmazie, 2024, v. 357, n. 2, p. 1, doi. 10.1002/ardp.202300447
By:
- Khudina, Olga G.;
- Grishchenko, Maria V.;
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Rudakova, Elena V.;
- Lushchekina, Sofya V.;
- Shchegolkov, Evgeny V.;
- Borisevich, Sophia S.;
- Burgart, Yanina V.;
- Saloutin, Victor I.;
- Charushin, Valery N.
Publication type:
Article
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
Published in:
Molecules, 2024, v. 29, n. 2, p. 321, doi. 10.3390/molecules29020321
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Y.;
- Timokhina, Elena N.;
- Serkov, Igor V.;
- Proshin, Alexey N.;
- Soldatova, Yuliya V.;
- Poletaeva, Darya A.;
- Faingold, Irina I.;
- Mumyatova, Viktoriya A.;
- Terentiev, Alexey A.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Bachurin, Sergey O.;
- Richardson, Rudy J.
Publication type:
Article
Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals.
Published in:
Molecules, 2023, v. 28, n. 1, p. 59, doi. 10.3390/molecules28010059
By:
- Burgart, Yanina V.;
- Elkina, Natalia A.;
- Shchegolkov, Evgeny V.;
- Krasnykh, Olga P.;
- Makhaeva, Galina F.;
- Triandafilova, Galina A.;
- Solodnikov, Sergey Yu.;
- Boltneva, Natalia P.;
- Rudakova, Elena V.;
- Kovaleva, Nadezhda V.;
- Serebryakova, Olga G.;
- Ulitko, Mariya V.;
- Borisevich, Sophia S.;
- Gerasimova, Natalia A.;
- Evstigneeva, Natalia P.;
- Kozlov, Sergey A.;
- Korolkova, Yuliya V.;
- Minin, Artem S.;
- Belousova, Anna V.;
- Mozhaitsev, Evgenii S.
Publication type:
Article
Synthesis of 4-Aminopyrazol-5-ols as Edaravone Analogs and Their Antioxidant Activity.
Published in:
Molecules, 2022, v. 27, n. 22, p. 7722, doi. 10.3390/molecules27227722
By:
- Burgart, Yanina V.;
- Makhaeva, Galina F.;
- Krasnykh, Olga P.;
- Borisevich, Sophia S.;
- Agafonova, Natalia A.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Rudakova, Elena V.;
- Shchegolkov, Evgeny V.;
- Triandafilova, Galina A.;
- Gazizov, Denis A.;
- Serebryakova, Olga G.;
- Ulitko, Maria V.;
- Khursan, Sergey L.;
- Saloutin, Victor I.;
- Richardson, Rudy J.
Publication type:
Article
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
Published in:
Molecules, 2022, v. 27, n. 3, p. 1060, doi. 10.3390/molecules27031060
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Rudakova, Elena V.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Yu.;
- Serkov, Igor V.;
- Proshin, Alexey N.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Korabecny, Jan;
- Soukup, Ondrej;
- Bachurin, Sergey O.;
- Richardson, Rudy J.
Publication type:
Article
Bis-γ-carbolines as new potential multitarget agents for Alzheimer's disease.
Published in:
Pure & Applied Chemistry, 2020, v. 92, n. 7, p. 1057, doi. 10.1515/pac-2019-1206
By:
- Makhaeva, Galina F.;
- Shevtsova, Elena F.;
- Aksinenko, Alexey Y.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Rudakova, Еlena V.;
- Pushkareva, Elena A.;
- Serkova, Tatyana P.;
- Dubova, Lyudmila G.;
- Shevtsov, Pavel N.;
- Sokolov, Vladimir B.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Bachurin, Sergey O.;
- Richardson, Rudy J.
Publication type:
Article
Focused design of polypharmacophoric neuroprotective compounds: Conjugates of γ-carbolines with carbazole derivatives and tetrahydrocarbazole.
Published in:
Pure & Applied Chemistry, 2017, v. 89, n. 8, p. 1167, doi. 10.1515/pac-2017-0308
By:
- Makhaeva, Galina F.;
- Sokolov, Vladimir B.;
- Shevtsova, Elena F.;
- Kovaleva, Nadezhda V.;
- Lushchekina, Sofya V.;
- Boltneva, Natalia P.;
- Rudakova, Elena V.;
- Aksinenko, Alexey Yu.;
- Shevtsov, Pavel N.;
- Neganova, Margarita E.;
- Dubova, Ludmila G.;
- Bachurin, Sergey O.
Publication type:
Article
Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds.
Published in:
Journal of Applied Toxicology, 2014, v. 34, n. 12, p. 1426, doi. 10.1002/jat.2977
By:
- Makhaeva, Galina F.;
- Rudakova, Elena V.;
- Hein, Nichole D.;
- Serebryakova, Olga G.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Fink, John K.;
- Richardson, Rudy J.
Publication type:
Article
Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.
Published in:
Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1219980
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Yu;
- Timokhina, Elena N.;
- Serebryakova, Olga G.;
- Shchepochkin, Alexander V.;
- Averkov, Maxim A.;
- Utepova, Irina A.;
- Demina, Nadezhda S.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Fisenko, Vladimir P.;
- Bachurin, Sergey O.;
- Chupakhin, Oleg N.;
- Charushin, Valery N.;
- Richardson, Rudy J.
Publication type:
Article
A Family of Titanium Complexes with Catechol Ligands: Structural Investigation and Catalytic Application.
Published in:
European Journal of Inorganic Chemistry, 2016, v. 2016, n. 33, p. 5215, doi. 10.1002/ejic.201600804
By:
- Bazhenova, Tamara A.;
- Kovaleva, Nadezhda V.;
- Shilov, Gennady V.;
- Petrova, Galina N.;
- Kuznetsov, Denis A.
Publication type:
Article
Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands.
Published in:
Molecules, 2021, v. 26, n. 18, p. 5527, doi. 10.3390/molecules26185527
By:
- Bachurin, Sergey O.;
- Makhaeva, Galina F.;
- Shevtsova, Elena F.;
- Aksinenko, Alexey Yu.;
- Grigoriev, Vladimir V.;
- Shevtsov, Pavel N.;
- Goreva, Tatiana V.;
- Epishina, Tatiana A.;
- Kovaleva, Nadezhda V.;
- Pushkareva, Elena A.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Gabrelyan, Alexey V.;
- Zamoyski, Vladimir L.;
- Dubova, Lyudmila G.;
- Rudakova, Elena V.;
- Fisenko, Vladimir P.;
- Bovina, Elena V.;
- Richardson, Rudy J.
Publication type:
Article
New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment.
Published in:
Molecules, 2020, v. 25, n. 24, p. 5891, doi. 10.3390/molecules25245891
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Rudakova, Elena V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Faingold, Irina I.;
- Poletaeva, Darya A.;
- Soldatova, Yuliya V.;
- Kotelnikova, Raisa A.;
- Serkov, Igor V.;
- Ustinov, Anatoly K.;
- Proshin, Alexey N.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Richardson, Rudy J.;
- Plech, Tomasz
Publication type:
Article
New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
Published in:
Molecules, 2020, v. 25, n. 17, p. 3915, doi. 10.3390/molecules25173915
By:
- Makhaeva, Galina F.;
- Kovaleva, Nadezhda V.;
- Boltneva, Natalia P.;
- Lushchekina, Sofya V.;
- Astakhova, Tatiana Yu.;
- Rudakova, Elena V.;
- Proshin, Alexey N.;
- Serkov, Igor V.;
- Radchenko, Eugene V.;
- Palyulin, Vladimir A.;
- Bachurin, Sergey O.;
- Richardson, Rudy J.;
- Kovarik, Zrinka
Publication type:
Article
Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41272-4
By:
- Bachurin, Sergey O.;
- Makhaeva, Galina F.;
- Shevtsova, Elena F.;
- Boltneva, Natalia P.;
- Kovaleva, Nadezhda V.;
- Lushchekina, Sofya V.;
- Rudakova, Elena V.;
- Dubova, Ludmila G.;
- Vinogradova, Daria V.;
- Sokolov, Vladimir B.;
- Aksinenko, Alexey Yu.;
- Fisenko, Vladimir P.;
- Richardson, Rudy J.;
- Aliev, Gjumrakch
Publication type:
Article

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