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Integration of Wnt-inhibitory activity and structural novelty scoring results to uncover novel bioactive natural products: new Bicyclo[3.3.1] non-3-ene-2,9-diones from the leaves of Hymenocardia punctata.
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- Frontiers in Chemistry, 2024, p. 01, doi. 10.3389/fchem.2024.1371982
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- Article
Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in Drosophila.
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- PLoS Genetics, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.pgen.1011204
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- Article
GNAO1 Mutations Affecting the N‐Terminal α‐Helix of Gαo Lead to Parkinsonism.
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- Movement Disorders, 2024, v. 39, n. 3, p. 601, doi. 10.1002/mds.29720
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Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing GNAO1 Mutation P170R.
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- Cells (2073-4409), 2023, v. 12, n. 20, p. 2469, doi. 10.3390/cells12202469
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- Article
Pediatric GNAO1 encephalopathies: from molecular etiology of the disease to drug discovery.
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- Neural Regeneration Research, 2023, v. 18, n. 10, p. 2188, doi. 10.4103/1673-5374.369106
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- Article
Shallow- and Deep-Water Ophiura Species Produce a Panel of Chlorin Compounds with Potent Photodynamic Anticancer Activities.
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- Antioxidants, 2023, v. 12, n. 2, p. 386, doi. 10.3390/antiox12020386
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- Article
Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28286-9
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- Article
Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01312-z
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- Article
Chemoenzymatic Synthesis of Complex Phenylpropanoid Derivatives by the Botrytis cinerea Secretome and Evaluation of Their Wnt Inhibition Activity.
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- Frontiers in Plant Science, 2022, v. 12, p. 1, doi. 10.3389/fpls.2021.805610
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Pediatric Encephalopathy: Clinical, Biochemical and Cellular Insights into the Role of Gln52 of GNAO1 and GNAI1 for the Dominant Disease.
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- Cells (2073-4409), 2021, v. 10, n. 10, p. 2749, doi. 10.3390/cells10102749
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- Article
Short stature and combined immunodeficiency associated with mutations in RGS10.
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- Science Signaling, 2021, v. 14, n. 693, p. 1, doi. 10.1126/scisignal.abc1940
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- Article
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02258-z
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- Article
A Cytotoxic Porphyrin from North Pacific Brittle Star Ophiura sarsii.
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- Marine Drugs, 2021, v. 19, n. 1, p. 11, doi. 10.3390/md19010011
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- Article
Beyond TNBC: Repositioning of Clofazimine Against a Broad Range of Wnt-Dependent Cancers.
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- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.602817
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- Article
High capacity in G protein-coupled receptor signaling.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02868-y
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- Article
Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.
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- Biofactors, 2017, v. 43, n. 2, p. 152, doi. 10.1002/biof.1315
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- Article
A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers.
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- Cancers, 2016, v. 8, n. 7, p. 66, doi. 10.3390/cancers8070066
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- Article
Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through uppression of heterotrimeric G proteins and Wnt endocytosis.
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- Biochemical Journal, 2016, v. 473, n. 4, p. 371, doi. 10.1042/BJ20150913
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- Article
Laparoscopic sacrocolpopexy in a patient with vault prolapse of the sigmoid stump.
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- International Urogynecology Journal, 2016, v. 27, n. 2, p. 315, doi. 10.1007/s00192-015-2766-x
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Identification of Novel Elements of the <i>Drosophila</i> Blisterome Sheds Light on Potential Pathological Mechanisms of Several Human Diseases.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0101133
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A Direct and Functional Interaction Between Go and Rab5 During G Protein-Coupled Receptor Signaling.
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- Science Signaling, 2010, v. 3, n. 136, p. 1, doi. 10.1126/scisignal.2000877
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- Article