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Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170260
By:
- Koussis, Konstantinos;
- Goulielmaki, Evi;
- Chalari, Anna;
- Withers-Martinez, Chrislaine;
- Siden-Kiamos, Inga;
- Matuschewski, Kai;
- Loukeris, Thanasis G.
Publication type:
Article
A multifunctional serine protease primes the malaria parasite for red blood cell invasion.
Published in:
EMBO Journal, 2009, v. 28, n. 6, p. 725, doi. 10.1038/emboj.2009.22
By:
- Koussis, Konstantinos;
- Withers-Martinez, Chrislaine;
- Yeoh, Sharon;
- Child, Matthew;
- Hackett, Fiona;
- Knuepfer, Ellen;
- Juliano, Luiz;
- Woehlbier, Ute;
- Bujard, Hermann;
- Blackman, Michael J.
Publication type:
Article
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
Published in:
PLoS Pathogens, 2024, v. 20, n. 6, p. 1, doi. 10.1371/journal.ppat.1012360
By:
- Koussis, Konstantinos;
- Haase, Silvia;
- Withers-Martinez, Chrislaine;
- Flynn, Helen R.;
- Kunzelmann, Simone;
- Christodoulou, Evangelos;
- Ibrahim, Fairouz;
- Skehel, Mark;
- Baker, David A.;
- Blackman, Michael J.
Publication type:
Article
A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
Published in:
PLoS Pathogens, 2023, v. 18, n. 6, p. 1, doi. 10.1371/journal.ppat.1011449
By:
- Ramaprasad, Abhinay;
- Burda, Paul-Christian;
- Koussis, Konstantinos;
- Thomas, James A.;
- Pietsch, Emma;
- Calvani, Enrica;
- Howell, Steven A.;
- MacRae, James I.;
- Snijders, Ambrosius P.;
- Gilberger, Tim-Wolf;
- Blackman, Michael J.
Publication type:
Article
Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121379
By:
- Tampaki, Zoi;
- Mwakubambanya, Ramadhan S.;
- Goulielmaki, Evi;
- Kaforou, Sofia;
- Kim, Kami;
- Waters, Andrew P.;
- Carruthers, Vern B.;
- Siden-Kiamos, Inga;
- Loukeris, Thanasis G.;
- Koussis, Konstantinos
Publication type:
Article
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.
Published in:
EMBO Journal, 2021, v. 40, n. 11, p. 1, doi. 10.15252/embj.2020107226
By:
- Tan, Michele S Y;
- Koussis, Konstantinos;
- Withers‐Martinez, Chrislaine;
- Howell, Steven A;
- Thomas, James A;
- Hackett, Fiona;
- Knuepfer, Ellen;
- Shen, Min;
- Hall, Matthew D;
- Snijders, Ambrosius P;
- Blackman, Michael J
Publication type:
Article

Found: 6

Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host.

A multifunctional serine protease primes the malaria parasite for red blood cell invasion.

Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.

A malaria parasite phospholipase facilitates efficient asexual blood stage egress.

Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium.

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.