Works matching AU Kotlyarov, Alexey

Results: 27

p38<sup>MAPK</sup>/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infection.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1245443

By:

Suwandi, Abdulhadi;
Menon, Manoj B.;
Kotlyarov, Alexey;
Grassl, Guntram A.;
Gaestel, Matthias

Publication type:

Article

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation.

Published in:

EMBO Journal, 1998, v. 17, n. 12, p. 3363, doi. 10.1093/emboj/17.12.3363

By:

Engel, Katrin;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis.

Published in:

PLoS Genetics, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pgen.1004558

By:

Menon, Manoj B.;
Sawada, Akihiro;
Chaturvedi, Anuhar;
Mishra, Pooja;
Schuster-Gossler, Karin;
Galla, Melanie;
Schambach, Axel;
Gossler, Achim;
Förster, Reinhold;
Heuser, Michael;
Kotlyarov, Alexey;
Kinoshita, Makoto;
Gaestel, Matthias

Publication type:

Article

The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU-Rich Element-Dependent Translation.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002977

By:

Tiedje, Christopher;
Ronkina, Natalia;
Tehrani, Mohammad;
Dhamija, Sonam;
Laass, Kathrin;
Holtmann, Helmut;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])–MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 13, p. 2467, doi. 10.1128/MCB.06633-11

By:

Brand, Frank;
Schumacher, Stefanie;
Kant, Shashi;
Menon, Manoj B.;
Simon, Ruth;
Turgeon, Benjamin;
Britsch, Stefan;
Meloche, Sylvain;
Gaestel, Matthias;
Kotlyarov, Alexey

Publication type:

Article

The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research.

Published in:

Autophagy, 2015, v. 11, n. 8, p. 1425, doi. 10.1080/15548627.2015.1059562

By:

Menon, Manoj B;
Dhamija, Sonam;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer.

Published in:

Cancers, 2023, v. 15, n. 1, p. 25, doi. 10.3390/cancers15010025

By:

Boudghene-Stambouli, Fadia;
Soulez, Mathilde;
Ronkina, Natalia;
Dörrie, Anneke;
Kotlyarov, Alexey;
Seternes, Ole-Morten;
Gaestel, Matthias;
Meloche, Sylvain

Publication type:

Article

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.

Published in:

EMBO Journal, 2009, v. 28, n. 10, p. 1392, doi. 10.1038/emboj.2009.100

By:

Schwermann, Jessica;
Rathinam, Chozhavendan;
Schubert, Maria;
Schumacher, Stefanie;
Noyan, Fatih;
Koseki, Haruhiko;
Kotlyarov, Alexey;
Klein, Christoph;
Gaestel, Matthias

Publication type:

Article

Scaffolding by ERK3 regulates MK5 in development.

Published in:

EMBO Journal, 2004, v. 23, n. 24, p. 4770, doi. 10.1038/sj.emboj.7600467

By:

Schumacher, Stefanie;
Laaß, Kathrin;
Kant, Shashi;
Shi, Yu;
Visel, Axel;
Gruber, Achim D;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

Interleukin‐10 targets p38 MAPK to modulate ARE‐dependent TNF mRNA translation and limit intestinal pathology.

Published in:

EMBO Journal, 2001, v. 20, n. 14, p. 3760, doi. 10.1093/emboj/20.14.3760

By:

Kontoyiannis, Dimitris;
Kotlyarov, Alexey;
Carballo, Ester;
Alexopoulou, Lena;
Blackshear, Perry J.;
Gaestel, Matthias;
Davis, Roger;
Flavell, Richard;
Kollias, George

Publication type:

Article

Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.

Published in:

EMBO Journal, 2001, v. 20, n. 14, p. 3760, doi. 10.1093/emboj/20.14.3760

By:

Kontoyiannis, Dimitris;
Kotlyarov, Alexey;
Carballo, Ester;
Alexopoulou, Lena;
Blackshear, Perry J.;
Gaestel, Matthias;
Davis, Roger;
Flavell, Richard;
Kollias, George

Publication type:

Article

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation – relevance in a mouse model of Parkinson’s disease.

Published in:

Journal of Neurochemistry, 2008, v. 105, n. 5, p. 2039, doi. 10.1111/j.1471-4159.2008.05310.x

By:

Thomas, Tobias;
Timmer, Marco;
Cesnulevicius, Konstantin;
Hitti, Edward;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

Cover Image, Volume 237, Number 4, April 2022.

Published in:

Journal of Cellular Physiology, 2022, v. 237, n. 4, p. i, doi. 10.1002/jcp.30764

By:

Soulez, Mathilde;
Tanguay, Pierre‐Luc;
Dô, Florence;
Dort, Junio;
Crist, Colin;
Kotlyarov, Alexey;
Gaestel, Matthias;
Ferron, Mathieu;
Dumont, Nicolas A.;
Meloche, Sylvain

Publication type:

Article

ERK3‐MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation.

Published in:

Journal of Cellular Physiology, 2022, v. 237, n. 4, p. 2271, doi. 10.1002/jcp.30695

By:

Soulez, Mathilde;
Tanguay, Pierre‐Luc;
Dô, Florence;
Dort, Junio;
Crist, Colin;
Kotlyarov, Alexey;
Gaestel, Matthias;
Ferron, Mathieu;
Dumont, Nicolas A.;
Meloche, Sylvain

Publication type:

Article

Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFa production.

Published in:

Biochemical Journal, 2013, v. 456, n. 2, p. 163, doi. 10.1042/BJ20130755

By:

MENON, Manoj B.;
TIEDJE, Christopher;
LAFERA, Juri;
RONKINA, Natalia;
KONEN, Timo;
KOTLYAROV, Alexey;
GAESTEL, Matthias

Publication type:

Article

Targeting innate immunity protein kinase signalling in inflammation.

Published in:

2009

By:

Gaestel, Matthias;
Kotlyarov, Alexey;
Kracht, Michael

Publication type:

journal article

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis.

Published in:

Nature Cell Biology, 1999, v. 1, n. 2, p. 94, doi. 10.1038/10061

By:

Kotlyarov, Alexey;
Neininger, Armin;
Schubert, Carola;
Eckert, Rolf;
Birchmeier, Carmen;
Volk, Hans-Dieter;
Gaestel, Matthias

Publication type:

Article

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136138

By:

Ronkina, Natalia;
Johansen, Claus;
Bohlmann, Lisa;
Lafera, Juri;
Menon, Manoj B.;
Tiedje, Christopher;
Laaß, Kathrin;
Turk, Benjamin E.;
Iversen, Lars;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

SB202190-Induced Cell Type-Specific Vacuole Formation and Defective Autophagy Do Not Depend on p38 MAP Kinase Inhibition.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023054

By:

Menon, Manoj B.;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 6, p. 33, doi. 10.1128/MCB.26.6.2399-2407.2006

By:

Hitti, Edward;
Iakovleva, Tatiana;
Brook, Matthew;
Deppenmeier, Stefanie;
Gruber, Achim D.;
Radzioch, Danuta;
Clark, Andrew R.;
Blackshear, Perry J.;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

Elimination of Protein Kinase MK5/PRAK Activity by Targeted Homologous Recombination.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 21, p. 7732, doi. 10.1128/MCB.23.21.7732-7741.2003

By:

Yu Shi;
Kotlyarov, Alexey;
Laaß, Kathrin;
Gruber, Achim D.;
Butt, Elke;
Marcus, Katrin;
Meyer, Helmut E.;
Freidrich, Anke;
Volk, Hans-Dieter;
Gaestel, Matthias

Publication type:

Article

5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01576-x

By:

Chauhan, Chanchal;
Kraemer, Andreas;
Knapp, Stefan;
Windheim, Mark;
Kotlyarov, Alexey;
Menon, Manoj B.;
Gaestel, Matthias

Publication type:

Article

PRMT5-mediated regulatory arginine methylation of RIPK3.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01299-z

By:

Chauhan, Chanchal;
Martinez-Val, Ana;
Niedenthal, Rainer;
Olsen, Jesper Velgaard;
Kotlyarov, Alexey;
Bekker-Jensen, Simon;
Gaestel, Matthias;
Menon, Manoj B.

Publication type:

Article

Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38<sup>MAPK</sup>/MK2 axis.

Published in:

Scientific Reports, 2016, p. 31219, doi. 10.1038/srep31219

By:

Ronkina, Natalia;
Lafera, Juri;
Kotlyarov, Alexey;
Gaestel, Matthias

Publication type:

Article

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis.

Published in:

Scientific Reports, 2016, p. 20007, doi. 10.1038/srep20007

By:

Abbey, Megha;
Hakim, Cosima;
Anand, Roopsee;
Lafera, Juri;
Schambach, Axel;
Kispert, Andreas;
Taft, Manuel H.;
Kaever, Volkhard;
Kotlyarov, Alexey;
Gaestel, Matthias;
Menon, Manoj B.

Publication type:

Article

HDM2 phosphorylation by MAPKAP kinase 2.

Published in:

Oncogene, 2005, v. 24, n. 12, p. 1965, doi. 10.1038/sj.onc.1208389

By:

Weber, Hans Oliver;
Ludwig, Robert L.;
Morrison, Deborah;
Kotlyarov, Alexey;
Gaestel, Matthias;
Vousden, Karen H.

Publication type:

Article

MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.

Published in:

European Journal of Neuroscience, 2008, v. 28, n. 4, p. 642, doi. 10.1111/j.1460-9568.2008.06382.x

By:

Thomas, Tobias;
Hitti, Edward;
Kotlyarov, Alexey;
Potschka, Heidrun;
Gaestel, Matthias

Publication type:

Article