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Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36312-7
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- Article
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.
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- eLife, 2020, p. 1, doi. 10.7554/eLife.58464
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- Article
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
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- eLife, 2018, p. 1, doi. 10.7554/eLife.33572
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- Article
Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
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- Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 244, doi. 10.1038/nsmb.2768
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- Article
Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 437, doi. 10.1038/nsmb.2002
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A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 1, p. 100, doi. 10.1038/nsmb.1945
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- Article
Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46706-w
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- Article
Structure of human drug transporters OATP1B1 and OATP1B3.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41552-8
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- Article
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
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- Nature Communications, 2023, n. 1, p. 1, doi. 10.1038/s41467-023-39262-2
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- Article
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.
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- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139695
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Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure.
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- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013960
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The 1.38 Å crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
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- Proteins, 2008, v. 71, n. 2, p. 525, doi. 10.1002/prot.21828
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- Article
The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.
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- Proteins, 2006, v. 62, n. 1, p. 8, doi. 10.1002/prot.20590
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- Article
Variability of conformations at crystal contacts in BPTI represent true low-energy structures: Correspondence among lattice packing and molecular dynamics structures.
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- Proteins, 1992, v. 14, n. 1, p. 65, doi. 10.1002/prot.340140108
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- Article
Structural effects induced by mutagenesis affected by crystal packing factors: The structure of a 30-51 disulfide mutant of basic pancreatic trypsin inhibitor.
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- Proteins, 1992, v. 14, n. 1, p. 75, doi. 10.1002/prot.340140109
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Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction.
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- Proteins, 1992, v. 12, n. 3, p. 203, doi. 10.1002/prot.340120302
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- Article
Analysis of solvent structure in proteins using neutron D<sub>2</sub>OH<sub>2</sub>O solvent maps: Pattern of primary and secondary hydration of trypsin.
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- Proteins, 1992, v. 12, n. 3, p. 223, doi. 10.1002/prot.340120303
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- Article
Crystal structure of subtilisin BPN′ variants containing disulfide bonds and cavities: Concerted structural rearrangements induced by mutagenesis.
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- Proteins, 1990, v. 7, n. 4, p. 343, doi. 10.1002/prot.340070406
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- Article
Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3991
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- Article
Structural Insights into Phospholipase Cε.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3961
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- Article
Structure of the rhodopsin–rhodopsin kinase complex defines the rules of engagement between G protein‐coupled receptors (GPCRs) and GPCR kinases.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.03635
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- Article
Structural Insights into PLCε: Discovery of an Integrated RA1 Domain and Novel Regulatory Elements.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.03032
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- Article
The Molecular Basis of Human ALKBH3 Mediated RNA N<sup>1</sup>‐methyladenosine (m<sup>1</sup>A) Demethylation.
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- Angewandte Chemie, 2024, v. 136, n. 7, p. 1, doi. 10.1002/ange.202313900
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- Article
Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06437-6
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- Article
The Molecular Basis of Human ALKBH3 Mediated RNA N<sup>1</sup>‐methyladenosine (m<sup>1</sup>A) Demethylation.
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- Angewandte Chemie International Edition, 2024, v. 63, n. 7, p. 1, doi. 10.1002/anie.202313900
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- Article
Functional Promiscuity of Squirrel Monkey Growth Hormone Receptor Toward both Primate and Nonprimate Growth Hormones.
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- Molecular Biology & Evolution, 2002, v. 19, n. 7, p. 1083, doi. 10.1093/oxfordjournals.molbev.a004166
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- Article
Total Chemical Synthesis and X-ray Crystal Structure of a Protein Diastereomer: [D-Gln 35]UbiquitinD.B. was supported by funding from the NSF MRSEC program at the University of Chicago (grant DMR 0213745). We acknowledge funding from DOE GTL program grant no. DE-FG02–04ER63786 (to S.B.K) and NIH grant no. GM54537 (to G.I.M). Portions of this work were performed at the DND-CAT (sector 5-ID) and IMCA-CAT (sector 17-ID) of the Advanced Photon Source. Use of the Advanced Photon Source was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences, under contract no. W-31–109-Eng-38. Use of the DND-CAT beamline is supported by the E.I. DuPont de Nemours, The Dow Chemical Company, the US National Science Foundation through grant no. DMR-9304725, and the State of Illinois through the Department of Commerce and the Board of Higher Education Grant IBHE HECA NWU 96. Use of the IMCA-CAT beamline at the Advanced Photon Source was supported by the companies of the
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- Angewandte Chemie, 2005, v. 117, n. 25, p. 3920, doi. 10.1002/ange.200463040
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- Article
Recognition of an α‐helical hairpin in P22 large terminase by a synthetic antibody fragment.
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- Acta Crystallographica: Section D, Structural Biology, 2020, v. 76, n. 9, p. 876, doi. 10.1107/S2059798320009912
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- Article
The structure of the C‐terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan‐specific synthetic Fab.
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- Acta Crystallographica: Section D, Structural Biology, 2018, v. 74, n. 7, p. 681, doi. 10.1107/S2059798318007878
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- Article
Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
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- Nature Structural Biology, 2000, v. 7, n. 9, p. 808
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- Article
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
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- Nature, 2013, v. 497, n. 7447, p. 137, doi. 10.1038/nature12120
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- Article
Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization.
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 48, p. 8156, doi. 10.1002/anie.200602946
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- Publication type:
- Article
Total Chemical Synthesis and X-ray Crystal Structure of a Protein Diastereomer: [D-Gln 35]UbiquitinD.B. was supported by funding from the NSF MRSEC program at the University of Chicago (grant DMR 0213745). We acknowledge funding from DOE GTL program grant no. DE-FG02–04ER63786 (to S.B.K) and NIH grant no. GM54537 (to G.I.M). Portions of this work were performed at the DND-CAT (sector 5-ID) and IMCA-CAT (sector 17-ID) of the Advanced Photon Source. Use of the Advanced Photon Source was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences, under contract no. W-31–109-Eng-38. Use of the DND-CAT beamline is supported by the E.I. DuPont de Nemours, The Dow Chemical Company, the US National Science Foundation through grant no. DMR-9304725, and the State of Illinois through the Department of Commerce and the Board of Higher Education Grant IBHE HECA NWU 96. Use of the IMCA-CAT beamline at the Advanced Photon Source was supported by the companies of the
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 25, p. 3852, doi. 10.1002/anie.200463040
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- Publication type:
- Article
Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.
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- Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 6, p. 1146, doi. 10.1002/pro.127
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- Article
Toward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (V<sub>H</sub>H) scaffold.
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- Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 7, p. 1175, doi. 10.1110/ps.034892.108
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- Article
Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
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- Protein Science: A Publication of the Protein Society, 2005, v. 14, n. 9, p. 2405, doi. 10.1110/ps.051519805
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- Article
Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization.
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- Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 9, p. 1960, doi. 10.1110/ps.03133903
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- Article
Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of alzheimer's amyloid β-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specificities.
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- Protein Science: A Publication of the Protein Society, 1997, v. 6, n. 9, p. 1806, doi. 10.1002/pro.5560060902
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- Article
Dissecting the energetics of protein α-helix C-cap termination through chemical protein synthesis.
- Published in:
- Nature Chemical Biology, 2006, v. 2, n. 3, p. 139, doi. 10.1038/nchembio766
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- Article
Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling.
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- Cell Communication & Signaling, 2015, v. 13, n. 1, p. 25, doi. 10.1186/s12964-014-0080-8
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- Article
Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15363-0
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- Article
Engineered antigen‐binding fragments for enhanced crystallization of antibody:antigen complexes.
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- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 1, p. 1, doi. 10.1002/pro.4824
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- Article
An engineered ultra‐high affinity Fab‐Protein G pair enables a modular antibody platform with multifunctional capability.
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- Protein Science: A Publication of the Protein Society, 2020, v. 29, n. 1, p. 141, doi. 10.1002/pro.3751
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- Article
A polar ring endows improved specificity to an antibody fragment.
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- Protein Science: A Publication of the Protein Society, 2016, v. 25, n. 7, p. 1290, doi. 10.1002/pro.2888
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- Article