Works by Kortylewski, Marcin

Results: 31

The dark side of Toll-like receptor signaling.

Published in:

OncoImmunology, 2014, v. 3, n. 3, p. N.PAG, doi. 10.4161/onci.27894

By:

Kortylewski, Marcin;
Pal, Sumanta K

Publication type:

Article

Push and release.

Published in:

OncoImmunology, 2014, v. 3, n. 2, p. N.PAG, doi. 10.4161/onci.27441

By:

Kortylewski, Marcin;
Kuo, Ya-Huei

Publication type:

Article

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 1, p. 41, doi. 10.1038/nri1995

By:

Yu, Hua;
Kortylewski, Marcin;
Pardoll, Drew

Publication type:

Article

SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function.

Published in:

Cell Death & Disease, 2018, v. 9, n. 6, p. 1, doi. 10.1038/s41419-018-0693-8

By:

Skrzypek, Klaudia;
Kusienicka, Anna;
Trzyna, Elzbieta;
Szewczyk, Barbara;
Ulman, Aleksandra;
Konieczny, Pawel;
Adamus, Tomasz;
Badyra, Bogna;
Kortylewski, Marcin;
Majka, Marcin

Publication type:

Article

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

Published in:

Nature Medicine, 2010, v. 16, n. 12, p. 1421, doi. 10.1038/nm.2250

By:

Heehyoung Lee;
Jiehui Deng;
Kujawski, Maciej;
Yang, Chunmei;
Yong Liu;
Herrmann, Andreas;
Kortylewski, Marcin;
Horne, David;
Somlo, George;
Forman, Stephen;
Jove, Richard;
Hua Yu

Publication type:

Article

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.

Published in:

Nature Medicine, 2005, v. 11, n. 12, p. 1314, doi. 10.1038/nm1325

By:

Kortylewski, Marcin;
Kujawski, Maciej;
Tianhong Wang;
Sheng Wei;
Shumin Zhang;
Pilon-Thomas, Shari;
Niu, Guilian;
Kay, Heidi;
Mulé, James;
Kerr, William G.;
Jove, Richard;
Pardoll, Drew;
Hua Yu

Publication type:

Article

Corrigendum: Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

Published in:

2004

By:

Wang, Tianhong;
Niu, Guilian;
Kortylewski, Marcin;
Burdelya, Lyudmila;
Sham, Kenneth;
Zhang, Shumin;
Bhattacharya, Raka;
Gabrilovich, Dmitry;
Heller, Richard;
Coppola, Domenico;
Dalton, William;
Jove, Richard;
Pardoll, Drew;
Yu, Hua

Publication type:

Correction Notice

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

Published in:

Nature Medicine, 2004, v. 10, n. 1, p. 48, doi. 10.1038/nm976

By:

Tianhong Wang, Ali;
Niu, Guilian;
Kortylewski, Marcin;
Burdelya, Lyudmila;
Shain, Kenneth;
Shumin Zhang;
Bhattacharya, Raka;
Gabrilovich, Dmirty;
Heller, Richard;
Coppola, Domenico;
Dalton, William;
Jove, Richard;
Pardoll, Drew;
Hua Yu

Publication type:

Article

Myeloid cells as a target for oligonucleotide therapeutics: turning obstacles into opportunities.

Published in:

Cancer Immunology, Immunotherapy, 2017, v. 66, n. 8, p. 979, doi. 10.1007/s00262-017-1966-2

By:

Kortylewski, Marcin;
Moreira, Dayson

Publication type:

Article

Targeting STAT3 in tumora-ssociated antigen-presenting cells as a strategy for kidney and bladder cancer immunotherapy.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1274781

By:

Alcantara, Marice B.;
Tang, Wilson S.;
Dongfang Wang;
Kaniowski, Damian;
Kang, Elaine;
Dizman, Nazli;
Chehrazi-Raffle, Alexander;
Meza, Luis;
Zengin, Zeynep;
Hall, Jeremy;
Hsu, JoAnn;
Egelston, Colt;
Moreira, Dayson;
Horsager, Alan;
Pal, Sumanta K.;
Kortylewski, Marcin

Publication type:

Article

MEETING HIGHLIGHTS: THE THIRD MARIE SKŁODOWSKA-CURIE SYMPOSIUM ON CANCER RESEARCH AND CARE AT ROSWELL PARK COMPREHENSIVE CANCER CENTER, BUFFALO, NY, SEPTEMBER 20-22, 2023.

Published in:

Wiadomości Lekarskie, 2023, v. 76, n. 12, p. 2543, doi. 10.36740/WLek202312101

By:

Kalinski, Pawel;
Kokolus, Kathleen M.;
Azrak, Rami;
Berezin, Mikhail Y.;
Brentjens, Renier;
Czerniecki, Brian;
Dubrov, Sergii;
Eaton, Kara;
Gandhi, Shipra;
Griffiths, Elizabeth A.;
Hyland, Andrew;
Kisailus, Adam;
Kortylewski, Marcin;
Koski, Gary K.;
Kotula, Leszek;
Ługowska, Iwona;
Matosevic, Sandro;
McAleer, Christopher;
Mikuła, Michał;
Nishimura, Michael I.

Publication type:

Article

Identification of mechanisms of resistance to treatment with abiraterone acetate or enzalutamide in patients with castration-resistant prostate cancer (CRPC).

Published in:

2018

By:

Pal, Sumanta Kumar;
Patel, Jaymala;
He, Miaoling;
Foulk, Brad;
Kraft, Katherine;
Smirnov, Denis A.;
Twardowski, Przemyslaw;
Kortylewski, Marcin;
Bhargava, Vipul;
Jones, Jeremy O.

Publication type:

journal article

Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation.

Published in:

Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-022-35222-4

By:

Esposito, Carla L.;
Autiero, Ida;
Sandomenico, Annamaria;
Li, H.;
Bassal, Mahmoud A.;
Ibba, Maria L.;
Wang, Dongfang;
Rinaldi, Lucrezia;
Ummarino, Simone;
Gaggi, Giulia;
Borchiellini, Marta;
Swiderski, Piotr;
Ruvo, Menotti;
Catuogno, Silvia;
Ebralidze, Alexander K.;
Kortylewski, Marcin;
de Franciscis, Vittorio;
Di Ruscio, Annalisa

Publication type:

Article

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice.

Published in:

2008

By:

Kujawski, Maciej;
Kortylewski, Marcin;
Heehyoung Lee;
Herrmann, Andreas;
Kay, Heidi;
Hua Yu;
Lee, Heehyoung;
Yu, Hua

Publication type:

journal article

Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain.

Published in:

Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-023-01079-3

By:

Sharma, Amit;
Fernandes, Diogo C.;
Reis, Rui L.;
Gołubczyk, Dominika;
Neumann, Silke;
Lukomska, Barbara;
Janowski, Miroslaw;
Kortylewski, Marcin;
Walczak, Piotr;
Oliveira, J. Miguel;
Maciaczyk, Jarek

Publication type:

Article

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.

Published in:

Nature Biotechnology, 2009, v. 27, n. 10, p. 925, doi. 10.1038/nbt.1564

By:

Kortylewski, Marcin;
Swiderski, Piotr;
Herrmann, Andreas;
Lin Wang;
Kowolik, Claudia;
Kujawski, Maciej;
Heehyoung Lee;
Scuto, Anna;
Yong Liu;
Chunmei Yang;
Jiehui Deng;
Soifer, Harris S.;
Raubitschek, Andrew;
Forman, Stephen;
Rossi, John J.;
Pardoll, Drew M.;
Jove, Richard;
Hua Yu

Publication type:

Article

Interleukin-6-Resistant Melanoma Cells Exhibit Reduced Activation of STAT3 and Lack of Inhibition of Cyclin E-Associated Kinase Activity.

Published in:

Journal of Investigative Dermatology, 2001, v. 117, n. 1, p. 132, doi. 10.1046/j.0022-202X.2001.01372.x

By:

Böhm, Markus;
Schulte, Ursula;
Funk, Jens Oliver;
Raghunath, Michael;
Behrmann, Iris;
Kortylewski, Marcin;
Heinrich, Peter C.;
Kues, Thorsten;
Luger, Thomas A.;
Schwarz, Thomas

Publication type:

Article

Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1.

Published in:

Oncogene, 1999, v. 18, n. 25, p. 3742, doi. 10.1038/sj.onc.1202708

By:

Kortylewski, Marcin;
Heinrich, Peter C;
Mackiewicz, Andrzej;
Schniertshauer, Ute;
Klingmüller, Ursula;
Nakajima, Koichi;
Hirano, Toshio;
Horn, Friedemann;
Behrmann, Iris

Publication type:

Article

Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer.

Published in:

Cancers, 2021, v. 13, n. 10, p. 2426, doi. 10.3390/cancers13102426

By:

Gleicher, Stephanie;
Porter, Baylee A.;
Nath, Disharee;
Li, Guanqun;
Khanna, Rakesh;
Goldberg, Hanan;
Kortylewski, Marcin;
Bratslavsky, Gennady;
Kotula, Leszek;
Urbanucci, Alfonso;
Tandefelt, Delila Gasi

Publication type:

Article

TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs.

Published in:

Journal of Leukocyte Biology, 2017, v. 102, n. 2, p. 423, doi. 10.1189/jlb.3MA1016-451RR

By:

Won, Haejung;
Moreira, Dayson;
Gao, Chan;
Duttagupta, Priyanka;
Zhao, Xingli;
Manuel, Edwin;
Diamond, Don;
Yuan, Yate‐Ching;
Liu, Zheng;
Jones, Jeremy;
D'Apuzzo, Massimo;
Pal, Sumanta;
Kortylewski, Marcin

Publication type:

Article

Myeloid cell-targeted STAT3 inhibition sensitizes head and neck cancers to radiotherapy and T cell-mediated immunity.

Published in:

2021

By:

Moreira, Dayson;
Sampath, Sagus;
Haejung Won;
White, Seok Voon;
Yu-Lin Su;
Alcantara, Marice;
Chongkai Wang;
Lee, Peter;
Maghami, Ellie;
Massarelli, Erminia;
Kortylewski, Marcin;
Won, Haejung;
Su, Yu-Lin;
Wang, Chongkai

Publication type:

journal article

Beclin-1 as a neutrophil-specific immune checkpoint.

Published in:

2019

By:

Yu-Lin Su;
Kortylewski, Marcin;
Su, Yu-Lin

Publication type:

journal article

CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 7, p. 2977, doi. 10.1172/JCI73174

By:

Herrmann, Andreas;
Priceman, Saul J.;
Kujawski, Maciej;
Hong Xin;
Cherryholmes, Gregory A.;
Wang Zhang;
Chunyan Zhang;
Lahtz, Christoph;
Kowolik, Claudia;
Forman, Steve J.;
Kortylewski, Marcin;
Hua Yu

Publication type:

Article

How to Train Your Dragon: Targeted Delivery of MicroRNA to Cancer Cells In Vivo.

Published in:

Molecular Therapy, 2014, v. 22, n. 6, p. 1070, doi. 10.1038/mt.2014.73

By:

Kortylewski, Marcin;
Nechaev, Sergey

Publication type:

Article

Interferon-γ-Mediated Growth Regulation of Melanoma Cells: Involvement of STAT1-Dependent and STAT1-Independent Signals.

Published in:

Journal of Investigative Dermatology, 2004, v. 122, n. 2, p. 414, doi. 10.1046/j.0022-202X.2004.22237.x

By:

Kortylewski, Marcin;
Komyod, Waraporn;
Kauffmann, Maria-Elisabeth;
Bosserhoff, Anja;
Heinrich, Peter C.;
Behrmann, Iris

Publication type:

Article

Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05750

By:

Amy Chow;
Weiying Zhou;
Liang Liu;
Fong, Miranda Y.;
Champer, Jackson;
Van Haute, Desiree;
Chin, Andrew R.;
Xiubao Ren;
Gugiu, Bogdan Gabriel;
Zhipeng Meng;
Wendong Huang;
Ngo, Vu;
Kortylewski, Marcin;
Shizhen Emily Wang

Publication type:

Article

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways.

Published in:

Oncogene, 2005, v. 24, n. 36, p. 5552, doi. 10.1038/sj.onc.1208719

By:

Qing Xu;
Briggs, Jon;
Sungman Park;
Niu, Guilian;
Kortylewski, Marcin;
Shumin Zhang;
Gritsko, Tanya;
Turkson, James;
Kay, Heidi;
Semenza, Gregg L.;
Cheng, Jin Q.;
Jove, Richard;
Yu, Hua

Publication type:

Article

Reduced T-cell Numbers and Elevated Levels of Immunomodulatory Cytokines in Metastatic Prostate Cancer Patients De Novo Resistant to Abiraterone and/or Enzalutamide Therapy.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 8, p. 1831, doi. 10.3390/ijms20081831

By:

Pal, Sumanta K.;
Moreira, Dayson;
Won, Haejung;
White, Seok Woon;
Duttagupta, Pryanka;
Lucia, Marc;
Jones, Jeremy;
Hsu, JoAnn;
Kortylewski, Marcin

Publication type:

Article

STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1803, doi. 10.3390/ijms19061803

By:

Su, Yu-Lin;
Banerjee, Shuvomoy;
White, Seok Voon;
Kortylewski, Marcin

Publication type:

Article

Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice.

Published in:

Glia (0894-1491), 2009, v. 57, n. 13, p. 1458, doi. 10.1002/glia.20863

By:

Zhang, Leying;
Alizadeh, Darya;
Van Handel, Michelle;
Kortylewski, Marcin;
Yu, Hua;
Badie, Behnam

Publication type:

Article

Editorial: Roles of Tumor-Recruited Myeloid Cells in Immune Evasion in Cancer.

Published in:

2021

By:

Kusmartsev, Sergei;
Serafini, Paolo;
Bharadwaj, Srinivas Nagaraj;
Kortylewski, Marcin

Publication type:

Editorial