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Social anhedonia as a Disrupted-in-Schizophrenia 1-dependent phenotype.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14102-3
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- Publication type:
- Article
Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity.
- Published in:
- 2016
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- Publication type:
- journal article
TRIOBP-1 Protein Aggregation Exists in Both Major Depressive Disorder and Schizophrenia, and Can Occur through Two Distinct Regions of the Protein.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11048, doi. 10.3390/ijms231911048
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- Publication type:
- Article
IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4516, doi. 10.3390/ijms21124516
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- Publication type:
- Article
Proteomic Studies Reveal Disrupted in Schizophrenia 1 as a Player in Both Neurodevelopment and Synaptic Function.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 1, p. 119, doi. 10.3390/ijms20010119
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- Publication type:
- Article
Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00026
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- Publication type:
- Article
Diurnal Variations in the Human Host Response to Endotoxin.
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- Journal of Infectious Diseases, 1996, v. 174, n. 5, p. 1040, doi. 10.1093/infdis/174.5.1040
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- Publication type:
- Article
Expression and characterization of a novel Aβ oligomer and fibril conformer-specific single-chain variable fragment (scFv) that was selected using Aβ1-16 linear sequence
- Published in:
- 2012
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- Publication type:
- Abstract
Oligomeric Aβ-targeting D-peptides and peptide-aminopyrazole-hybrids for treatment of Alzheimer's disease
- Published in:
- 2011
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- Publication type:
- Abstract
Oral treatment with an Aβ42 oligomer modulating D-amino acid peptide improves cognitive behavior of APP/ PS1 double transgenic mice
- Published in:
- 2009
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- Abstract
P3-344: γ-secretase–dependent APP processing occurs either at the plasma membrane or in the endocytic compartments independent of the APP wild-type or APP Swedish variant
- Published in:
- 2008
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- Publication type:
- Abstract
Gesteigerte Wirksamkeit durch Synergismus: Verknüpfung unabhängiger Wirkstoffklassen zu Hybridsubstanzen.
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 46, p. 8925, doi. 10.1002/ange.201004437
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- Publication type:
- Article
Disrupted‐in‐schizophrenia 1 functional polymorphisms and D<sub>2</sub>/D<sub>3</sub> receptor availability: A [<sup>11</sup>C]‐(+)‐PHNO imaging study.
- Published in:
- Genes, Brain & Behavior, 2019, v. 18, n. 8, p. N.PAG, doi. 10.1111/gbb.12596
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- Publication type:
- Article
Revisiting rodent models: Octodon degus as Alzheimer's disease model?
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0363-y
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- Publication type:
- Article
50‐kHz ultrasonic vocalizations do not signal social anhedonia in transgenic DISC1 rats.
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- Brain & Behavior, 2023, v. 13, n. 5, p. 1, doi. 10.1002/brb3.2984
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- Publication type:
- Article
Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia.
- Published in:
- Scientific Reports, 2016, p. 34946, doi. 10.1038/srep34946
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- Publication type:
- Article
Aggregation of the Protein TRIOBP-1 and Its Potential Relevance to Schizophrenia.
- Published in:
- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111196
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- Publication type:
- Article
Aging-Induced Proteostatic Changes in the Rat Hippocampus Identify ARP3, NEB2 and BRAG2 as a Molecular Circuitry for Cognitive Impairment.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075112
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- Publication type:
- Article
Characterization of a Single-Chain Variable Fragment Recognizing a Linear Epitope of Aβ: A Biotechnical Tool for Studies on Alzheimer’s Disease?
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059820
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- Publication type:
- Article
Quinpramine Ameliorates Rat Experimental Autoimmune Neuritis and Redistributes MHC Class II Molecules.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021223
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- Publication type:
- Article
Decreased nuclear distribution nudE-like 1 enzyme activity in an animal model with dysfunctional disrupted-in-schizophrenia 1 signaling featuring aberrant neurodevelopment and amphetamine-supersensitivity.
- Published in:
- 2020
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- Publication type:
- journal article
Human and rat brain lipofuscin proteome.
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- Proteomics, 2012, v. 12, n. 15/16, p. 2445, doi. 10.1002/pmic.201100668
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- Publication type:
- Article
Insolubility of Disrupted-in-Schizophrenia 1 Disrupts Oligomer-Dependent Interactions with Nuclear Distribution Element 1 and Is Associated with Sporadic Mental Disease.
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- Journal of Neuroscience, 2008, v. 28, n. 15, p. 3839, doi. 10.1523/JNEUROSCI.5389-07.2008
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- Publication type:
- Article
Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development.
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- Journal of Neuroscience, 2006, v. 26, n. 41, p. 12768, doi. 10.1523/JNEUROSCI.3355-09.2009
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- Publication type:
- Article
Cellular prion protein participates in amyloid-β transcytosis across the blood-brain barrier.
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- Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 4, p. 628, doi. 10.1038/jcbfm.2012.7
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- Publication type:
- Article
Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0486-6
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- Publication type:
- Article
Soluble amyloid-β dimers are resistant to amyloid-β prion conversion in vivo suggesting antiprion properties.
- Published in:
- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 2, p. 1, doi. 10.1111/nan.12895
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- Publication type:
- Article
Soluble amyloid‐β dimers are resistant to amyloid‐β prion conversion in vivo suggesting antiprion properties.
- Published in:
- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 1, p. 1, doi. 10.1111/nan.12895
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- Publication type:
- Article
The interaction of insoluble Amyloid‐β with soluble Amyloid‐β dimers decreases Amyloid‐β plaque numbers.
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- Neuropathology & Applied Neurobiology, 2021, v. 47, n. 5, p. 603, doi. 10.1111/nan.12685
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- Publication type:
- Article
C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β.
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- Brain: A Journal of Neurology, 2012, v. 135, n. 7, p. 2140, doi. 10.1093/brain/aws120
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- Publication type:
- Article
Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling.
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- Brain: A Journal of Neurology, 2010, v. 133, n. 2, p. 375, doi. 10.1093/brain/awp298
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- Publication type:
- Article
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
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- 2016
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- Publication type:
- journal article
Disrupted‐in‐schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first‐episode psychosis.
- Published in:
- Psychiatry & Clinical Neurosciences, 2023, v. 77, n. 12, p. 665, doi. 10.1111/pcn.13594
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- Publication type:
- Article
Human prion strain selection in transgenic mice.
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- Annals of Neurology, 2010, v. 68, n. 2, p. 151, doi. 10.1002/ana.22104
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- Publication type:
- Article
DISC1 regulates expression of the neurotrophin VGF through the PI3K/ AKT/ CREB pathway.
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- Journal of Neurochemistry, 2015, v. 135, n. 3, p. 598, doi. 10.1111/jnc.13258
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- Publication type:
- Article
Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.
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- Journal of Neurochemistry, 2011, v. 116, n. 3, p. 385, doi. 10.1111/j.1471-4159.2010.07118.x
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- Publication type:
- Article
α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation.
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- Journal of Neurochemistry, 2009, v. 111, n. 6, p. 1369, doi. 10.1111/j.1471-4159.2009.06420.x
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- Publication type:
- Article
N-Acetylaspartate and neurofilaments as biomarkers of axonal damage in patients with progressive forms of multiple sclerosis.
- Published in:
- Journal of Neurology, 2014, v. 261, n. 12, p. 2338, doi. 10.1007/s00415-014-7507-4
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- Publication type:
- Article
The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study.
- Published in:
- Human Molecular Genetics, 2018, v. 27, n. 20, p. 3498, doi. 10.1093/hmg/ddy242
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- Publication type:
- Article
Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 22, p. 5859, doi. 10.1093/hmg/ddu303
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- Publication type:
- Article
Behavioral Resilience and Sensitivity to Locally Restricted Cortical Migration Deficits Induced by In Utero Knockdown of Disabled-1 in the Adult Rat.
- Published in:
- Cerebral Cortex, 2017, v. 27, n. 3, p. 2052, doi. 10.1093/cercor/bhw060
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- Publication type:
- Article
Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt–Jakob disease.
- Published in:
- European Journal of Neuroscience, 2010, v. 31, n. 11, p. 2024, doi. 10.1111/j.1460-9568.2010.07224.x
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- Publication type:
- Article
Disrupted‐in‐schizophrenia 1 overexpression disrupts hippocampal coding and oscillatory synchronization.
- Published in:
- Hippocampus, 2019, v. 29, n. 9, p. 802, doi. 10.1002/hipo.23076
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- Publication type:
- Article
Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats.
- Published in:
- Frontiers in Psychiatry, 2019, p. N.PAG, doi. 10.3389/fpsyt.2019.00222
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- Publication type:
- Article
Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments.
- Published in:
- 2006
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- Publication type:
- Correction Notice
Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments.
- Published in:
- Journal of Neurochemistry, 2006, v. 98, n. 3, p. 748, doi. 10.1111/j.1471-4159.2006.03889.x
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- Publication type:
- Article
Loss of Prion Protein Leads to Age-Dependent Behavioral Abnormalities and Changes in Cytoskeletal Protein Expression.
- Published in:
- Molecular Neurobiology, 2014, v. 50, n. 3, p. 923, doi. 10.1007/s12035-014-8655-3
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- Publication type:
- Article
Hybrid Compounds.
- Published in:
- BioDrugs, 2012, v. 26, n. 1, p. 21
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- Publication type:
- Article
Vaccine Approaches to Prevent and Treat Prion Infection: Progress and Challenges.
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- BioDrugs, 2008, v. 22, n. 1, p. 45
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- Publication type:
- Article
Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191162
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- Publication type:
- Article