Works by Korolchuk, Viktor I.

Results: 43
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    Complement modulation reverses pathology in Y402H‐retinal pigment epithelium cell model of age‐related macular degeneration by restoring lysosomal function.

    Published in:
    Stem Cells Translational Medicine, 2020, v. 9, n. 12, p. 1585, doi. 10.1002/sctm.20-0211
    By:
    • Cerniauskas, Edvinas;
    • Kurzawa‐Akanbi, Marzena;
    • Xie, Long;
    • Hallam, Dean;
    • Moya‐Molina, Marina;
    • White, Kathryn;
    • Steel, David;
    • Doherty, Mary;
    • Whitfield, Phil;
    • Al‐Aama, Jumana;
    • Armstrong, Lyle;
    • Kavanagh, David;
    • Lambris, John D.;
    • Korolchuk, Viktor I.;
    • Harris, Claire;
    • Lako, Majlinda
    Publication type:
    Article
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    Oncogenic PIK3CA corrupts growth factor signaling specificity.

    Published in:
    Molecular Systems Biology, 2025, v. 21, n. 2, p. 126, doi. 10.1038/s44320-024-00078-x
    By:
    • Madsen, Ralitsa R;
    • Le Marois, Alix;
    • Mruk, Oliwia N;
    • Voliotis, Margaritis;
    • Yin, Shaozhen;
    • Sufi, Jahangir;
    • Qin, Xiao;
    • Zhao, Salome J;
    • Gorczynska, Julia;
    • Morelli, Daniele;
    • Davidson, Lindsay;
    • Sahai, Erik;
    • Korolchuk, Viktor I;
    • Tape, Christopher J;
    • Vanhaesebroeck, Bart
    Publication type:
    Article
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    Severe white matter astrocytopathy in CADASIL.

    Published in:
    Brain Pathology, 2018, v. 28, n. 6, p. 832, doi. 10.1111/bpa.12621
    By:
    • Hase, Yoshiki;
    • Chen, Aiqing;
    • Bates, Letitia L.;
    • Craggs, Lucinda J.L.;
    • Yamamoto, Yumi;
    • Gemmell, Elizabeth;
    • Oakley, Arthur E.;
    • Korolchuk, Viktor I.;
    • Kalaria, Raj N.
    Publication type:
    Article
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    Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling.

    Published in:
    EMBO Journal, 2024, v. 43, n. 17, p. 3627, doi. 10.1038/s44318-024-00177-3
    By:
    • Domingues, Neuza;
    • Catarino, Steve;
    • Cristóvão, Beatriz;
    • Rodrigues, Lisa;
    • Carvalho, Filomena A;
    • Sarmento, Maria João;
    • Zuzarte, Mónica;
    • Almeida, Jani;
    • Ribeiro-Rodrigues, Teresa;
    • Correia-Rodrigues, Ânia;
    • Fernandes, Fábio;
    • Rodrigues-Santos, Paulo;
    • Aasen, Trond;
    • Santos, Nuno C;
    • Korolchuk, Viktor I;
    • Gonçalves, Teresa;
    • Milosevic, Ira;
    • Raimundo, Nuno;
    • Girão, Henrique
    Publication type:
    Article
    13

    NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy.

    Published in:
    EMBO Journal, 2023, v. 42, n. 5, p. 1, doi. 10.15252/embj.2022111372
    By:
    • Kataura, Tetsushi;
    • Otten, Elsje G;
    • Rabanal‐Ruiz, Yoana;
    • Adriaenssens, Elias;
    • Urselli, Francesca;
    • Scialo, Filippo;
    • Fan, Lanyu;
    • Smith, Graham R;
    • Dawson, William M;
    • Chen, Xingxiang;
    • Yue, Wyatt W;
    • Bronowska, Agnieszka K;
    • Carroll, Bernadette;
    • Martens, Sascha;
    • Lazarou, Michael;
    • Korolchuk, Viktor I
    Publication type:
    Article
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    Rapamycin improves healthspan but not inflammaging in nfκb1<sup>−/−</sup> mice.

    Published in:
    Aging Cell, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1111/acel.12882
    By:
    • Correia‐Melo, Clara;
    • Birch, Jodie;
    • Fielder, Edward;
    • Rahmatika, Dina;
    • Taylor, Jennifer;
    • Chapman, James;
    • Lagnado, Anthony;
    • Carroll, Bernadette M.;
    • Miwa, Satomi;
    • Richardson, Gavin;
    • Jurk, Diana;
    • Oakley, Fiona;
    • Mann, Jelena;
    • Mann, Derek A.;
    • Korolchuk, Viktor I.;
    • Passos, João F.
    Publication type:
    Article
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    Lysosome-mediated processing of chromatin in senescence.

    Published in:
    Journal of Cell Biology, 2013, v. 202, n. 1, p. 129, doi. 10.1083/jcb.201212110
    By:
    • Ivanov, Andre;
    • Pawlikowski, Jeff;
    • Manoharan, Indrani;
    • van Tuyn, John;
    • Nelson, David M.;
    • Taranjit Singh Rai;
    • Shah, Parisha P.;
    • Hewitt, Graeme;
    • Korolchuk, Viktor I.;
    • Passos, Joao F.;
    • Hong Wu;
    • Berger, Shelley L.;
    • Adams, Peter D.
    Publication type:
    Article
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    SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.

    Published in:
    Autophagy, 2016, v. 12, n. 10, p. 1917, doi. 10.1080/15548627.2016.1210368
    By:
    • Hewitt, Graeme;
    • Carroll, Bernadette;
    • Sarallah, Rezazadeh;
    • Correia-Melo, Clara;
    • Ogrodnik, Mikołaj;
    • Nelson, Glyn;
    • Otten, Elsje G.;
    • Manni, Diego;
    • Antrobus, Robin;
    • Morgan, Brian A.;
    • von Zglinicki, Thomas;
    • Jurk, Diana;
    • Seluanov, Andrei;
    • Gorbunova, Vera;
    • Johansen, Terje;
    • Passos, João F.;
    • Korolchuk, Viktor I.
    Publication type:
    Article
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    Impaired autophagy in Lafora disease.

    Published in:
    Autophagy, 2010, v. 6, n. 7, p. 991, doi. 10.4161/auto.6.7.13308
    By:
    • Knecht, Erwin;
    • Aguado, Carmen;
    • Sarkar, Sovan;
    • Korolchuk, Viktor I.;
    • Criado-García, Olga;
    • Vernia, Santiago;
    • Boya, Patricia;
    • Sanz, Pascual;
    • de Córdoba, Santiago Rodríguez;
    • Rubinsztein, David C.
    Publication type:
    Article
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    Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02746-z
    By:
    • Carroll, Bernadette;
    • Otten, Elsje G.;
    • Manni, Diego;
    • Stefanatos, Rhoda;
    • Menzies, Fiona M.;
    • Smith, Graham R.;
    • Jurk, Diana;
    • Kenneth, Niall;
    • Wilkinson, Simon;
    • Passos, Joao F.;
    • Attems, Johannes;
    • Veal, Elizabeth A.;
    • Teyssou, Elisa;
    • Seilhean, Danielle;
    • Millecamps, Stéphanie;
    • Eskelinen, Eeva-Liisa;
    • Bronowska, Agnieszka K.;
    • Rubinsztein, David C.;
    • Sanz, Alberto;
    • Korolchuk, Viktor I.
    Publication type:
    Article
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    Lysosomal positioning coordinates cellular nutrient responses.

    Published in:
    Nature Cell Biology, 2011, v. 13, n. 4, p. 453, doi. 10.1038/ncb2204
    By:
    • Korolchuk, Viktor I.;
    • Saiki, Shinji;
    • Lichtenberg, Maike;
    • Siddiqi, Farah H.;
    • Roberts, Esteban A.;
    • Imarisio, Sara;
    • Jahreiss, Luca;
    • Sarkar, Sovan;
    • Futter, Marie;
    • Menzies, Fiona M.;
    • O'Kane, Cahir J.;
    • Deretic, Vojo;
    • Rubinsztein, David C.
    Publication type:
    Article
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    Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.

    Published in:
    eLife, 2016, p. 1, doi. 10.7554/eLife.11058
    By:
    • Carroll, Bernadette;
    • Maetzel, Dorothea;
    • Maddocks, Oliver D. K.;
    • Otten, Gisela;
    • Ratcliff, Matthew;
    • Smith, Graham R.;
    • Dunlop, Elaine A.;
    • Passos, João F.;
    • Davies, Owen R.;
    • Jaenisch, Rudolf;
    • Tee, Andrew R.;
    • Sarkar, Sovan;
    • Korolchuk, Viktor I.
    Publication type:
    Article
    34

    Developmental mitochondrial complex I activity determines lifespan.

    Published in:
    EMBO Reports, 2025, v. 26, n. 8, p. 1957, doi. 10.1038/s44319-025-00416-6
    By:
    • Stefanatos, Rhoda;
    • Robertson, Fiona;
    • Castejon-Vega, Beatriz;
    • Yu, Yizhou;
    • Uribe, Alejandro Huerta;
    • Myers, Kevin;
    • Kataura, Tetsushi;
    • Korolchuk, Viktor I;
    • Maddocks, Oliver D K;
    • Martins, L Miguel;
    • Sanz, Alberto
    Publication type:
    Article
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    Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models.

    Published in:
    Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06770-y
    By:
    • Kataura, Tetsushi;
    • Sedlackova, Lucia;
    • Sun, Congxin;
    • Kocak, Gamze;
    • Wilson, Niall;
    • Banks, Peter;
    • Hayat, Faisal;
    • Trushin, Sergey;
    • Trushina, Eugenia;
    • Maddocks, Oliver D. K.;
    • Oblong, John E.;
    • Miwa, Satomi;
    • Imoto, Masaya;
    • Saiki, Shinji;
    • Erskine, Daniel;
    • Migaud, Marie E.;
    • Sarkar, Sovan;
    • Korolchuk, Viktor I.
    Publication type:
    Article
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    mTORC1 as the main gateway to autophagy.

    Published in:
    Essays in Biochemistry, 2017, v. 61, n. 6, p. 565, doi. 10.1042/EBC20170027
    By:
    • Rabanal-Ruiz, Yoana;
    • Otten, Elsje G.;
    • Korolchuk, Viktor I.
    Publication type:
    Article
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