Works by Korbutt, Gregory

Results: 64

Porcine Islet Xenografts: a Clinical Source of ß-Cell Grafts.

Published in:

2017

By:

Salama, Bassem;
Korbutt, Gregory;
Salama, Bassem F;
Korbutt, Gregory S

Publication type:

journal article

Bioengineering a highly vascularized matrix for the ectopic transplantation of islets.

Published in:

Islets, 2013, v. 5, n. 5, p. 1, doi. 10.4161/isl.27175

By:

Ellis, Cara E.;
Vulesevic, Branka;
Suuronen, Erik;
Yeung, Telford;
Seeberger, Karen;
Korbutt, Gregory S.

Publication type:

Article

Possible link between ectopic pancreas and holoprosencephaly.

Published in:

Islets, 2012, v. 4, n. 3, p. 207, doi. 10.4161/isl.20478

By:

Kin, Tatsuya;
Korbutt, Gregory S.;
Shapiro, A. M. James

Publication type:

Article

Ferroptosis-inducing agents compromise in vitro human islet viability and function.

Published in:

Cell Death & Disease, 2018, v. 9, n. 6, p. 1, doi. 10.1038/s41419-018-0506-0

By:

Bruni, Antonio;
Pepper, Andrew R.;
Pawlick, Rena L.;
Gala-Lopez, Boris;
Gamble, Anissa F.;
Kin, Tatsuya;
Seeberger, Karen;
Korbutt, Gregory S.;
Bornstein, Stefan R.;
Linkermann, Andreas;
Shapiro, A. M. James

Publication type:

Article

Collagen-chitosan-laminin hydrogels for the delivery of insulin-producing tissue.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2016, v. 10, n. 10, p. E397, doi. 10.1002/term.1829

By:

McEwan, Kimberly;
Padavan, Donna T.;
Ellis, Cara;
McBane, Joanne E.;
Vulesevic, Branka;
Korbutt, Gregory S.;
Suuronen, Erik J.

Publication type:

Article

Effects of N-Acetylcysteine on Intestinal Reoxygenation Injury in Hypoxic Newborn Piglets Resuscitated with 100 Oxygen.

Published in:

Neonatology (16617800), 2009, v. 96, n. 3, p. 162, doi. 10.1159/000210089

By:

Scott T. Johnson;
David L. Bigam;
Marwan Emara;
Graham Slack;
Laurence D. Jewell;
Laila Obaid;
Gregory Korbutt;
John Van Aerde;
Po-Yin Cheung

Publication type:

Article

Improved islet recovery and efficacy through co-culture and co-transplantation of islets with human adipose-derived mesenchymal stem cells.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206449

By:

Gamble, Anissa;
Pawlick, Rena;
Pepper, Andrew R.;
Bruni, Antonio;
Adesida, Adetola;
Senior, Peter A.;
Korbutt, Gregory S.;
Shapiro, A. M. James

Publication type:

Article

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.

Published in:

Nature Medicine, 2006, v. 12, n. 3, p. 304, doi. 10.1038/nm1375

By:

Cardona, Kenneth;
Korbutt, Gregory S.;
Milas, Zvonimir;
Lyon, James;
Cano, Jose;
Wanhong Jiang;
Bello-Laborn, Hameeda;
Hacquoil, Brad;
Strobert, Elizabeth;
Gangappa, Shivaprakash;
Weber, Collin J.;
Pearson, Thomas C.;
Rajotte, Ray V.;
Larsen, Christian P.

Publication type:

Article

Human islet function following 20 years of cryogenic biobanking.

Published in:

Diabetologia, 2015, v. 58, n. 7, p. 1503, doi. 10.1007/s00125-015-3598-4

By:

Manning Fox, Jocelyn;
Lyon, James;
Dai, Xiao;
Wright, Robert;
Hayward, Julie;
Bunt, Martijn;
Kin, Tatsuya;
Shapiro, A.;
McCarthy, Mark;
Gloyn, Anna;
Ungrin, Mark;
Lakey, Jonathan;
Kneteman, Norm;
Warnock, Garth;
Korbutt, Gregory;
Rajotte, Raymond;
MacDonald, Patrick

Publication type:

Article

Evaluation of a Collagen-Chitosan Hydrogel for Potential Use as a Pro-Angiogenic Site for Islet Transplantation.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077538

By:

McBane, Joanne E.;
Vulesevic, Branka;
Padavan, Donna T.;
McEwan, Kimberly A.;
Korbutt, Gregory S.;
Suuronen, Erik J.

Publication type:

Article

Human Mesenchymal Stem Cells Protect Human Islets from Pro-Inflammatory Cytokines.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0038189

By:

Yeung, Telford Y.;
Seeberger, Karen L.;
Kin, Tatsuya;
Adesida, Adetola;
Jomha, Nadr;
Shapiro, A. M.James;
Korbutt, Gregory S.

Publication type:

Article

Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice.

Published in:

Cardiovascular Research, 2014, v. 101, n. 2, p. 306, doi. 10.1093/cvr/cvt259

By:

Vulesevic, Branka;
McNeill, Brian;
Geoffrion, Michele;
Kuraitis, Drew;
McBane, Joanne E.;
Lochhead, Marina;
Vanderhyden, Barbara C.;
Korbutt, Gregory S.;
Milne, Ross W.;
Suuronen, Erik J.

Publication type:

Article

Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.

Published in:

2005

By:

Kin, Tatsuya;
Korbutt, Gregory S.;
Kobayashi, Tsunehiro;
Dufour, Jannette M.;
Rajotte, Ray V.

Publication type:

journal article

Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome.

Published in:

2004

By:

Street, Cale N;
Lakey, Jonathan R T;
Shapiro, A M James;
Imes, Sharleen;
Rajotte, Ray V;
Ryan, Edmond A;
Lyon, James G;
Kin, Tatsuya;
Avila, Jose;
Tsujimura, Toshiaki;
Korbutt, Gregory S

Publication type:

journal article

Islet Graft Assessment in the Edmonton Protocol.

Published in:

Diabetes, 2004, v. 53, n. 12, p. 3107, doi. 10.2337/diabetes.53.12.3107

By:

Street, Cale N.;
Lakey, Jonathan R. T.;
Shapiro, A.M. James;
Imes, Sharleen;
Rajotte, Ray V.;
Ryan, Edmond A.;
Lyon, James G.;
Kin, Tatsuya;
Avila, Jose;
Tsujimura, Toshiaki;
Korbutt, Gregory S.

Publication type:

Article

The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection.

Published in:

2003

By:

Rayat, Gina R.;
Johnson, Zachary A.;
Beilke, Joshua N.;
Korbutt, Gregory S.;
Rajotte, Ray V.;
Gill, Ronald G.

Publication type:

journal article

Successful islet transplantation: continued insulin reserve provides long-term glycemic control.

Published in:

2002

By:

Ryan, Edmond A;
Lakey, Jonathan R T;
Paty, Breay W;
Imes, Sharleen;
Korbutt, Gregory S;
Kneteman, Norman M;
Bigam, David;
Rajotte, Ray V;
Shapiro, A M James

Publication type:

journal article

Successful Islet Transplantation.

Published in:

Diabetes, 2002, v. 51, n. 7, p. 2148, doi. 10.2337/diabetes.51.7.2148

By:

Ryan, Edmond A.;
Lakey, Jonathan R.T.;
Paty, Breay W.;
Imes, Sharleen;
Korbutt, Gregory S.;
Kneteman, Norman M.;
Bigam, David;
Rajotte, Ray V.;
Shapiro, A.M. James

Publication type:

Article

Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.

Published in:

2000

By:

Suarez-Pinzon, Wilma;
Korbutt, Gregory S.;
Power, Robert;
Hooton, Jonathan;
Rajotte, Ray V.;
Rabinovitch, Alex;
Suarez-Pinzon, W;
Korbutt, G S;
Power, R;
Hooton, J;
Rajotte, R V;
Rabinovitch, A

Publication type:

journal article

Neonatal porcine islet cells induce human CD4+, but not CD8+, lymphocyte proliferation and resist cell-mediated cytolytic injury in vitro.

Published in:

1999

By:

Murray, Allan G.;
Nelson, Randy C.;
Rayat, Gina R.;
Elliott, John F.;
Korbutt, Gregory S.;
Murray, A G;
Nelson, R C;
Rayat, G R;
Elliott, J F;
Korbutt, G S

Publication type:

journal article

Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction.

Published in:

1999

By:

Rabinovitch, Alex;
Suarez-Pinzon, Wilma;
Strynadka, Ken;
Ju, Qida;
Edelstein, Diane;
Brownlee, Michael;
Korbutt, Gregory S.;
Rajotte, Ray V.;
Rabinovitch, A;
Suarez-Pinzon, W;
Strynadka, K;
Ju, Q;
Edelstein, D;
Brownlee, M;
Korbutt, G S;
Rajotte, R V

Publication type:

journal article

Expression of Galalpha (1,3) Gal on neonatal porcine islet beta-cells and susceptibility of...

Published in:

Diabetes, 1998, v. 47, n. 9, p. 1406, doi. 10.2337/diabetes.47.9.1406

By:

Rayat, Gina R.;
Rajotte, Ray V.;
Elliott, John F.;
Korbutt, Gregory S.

Publication type:

Article

Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression.

Published in:

1997

By:

Korbutt, Gregory S.;
Elliott, John F.;
Rajotte, Ray V.;
Korbutt, G S;
Elliott, J F;
Rajotte, R V

Publication type:

journal article

Cold storage of rat pancreas before purification of islet beta-cells.

Published in:

1992

By:

Korbutt, Gregory S.;
Pipeleers, Daniel G.;
Korbutt, G S;
Pipeleers, D G

Publication type:

journal article

Effect of Thioketal Antioxidants on Islet Cell Transplantation.

Published in:

Advanced Therapeutics, 2023, v. 6, n. 1, p. 1, doi. 10.1002/adtp.202200132

By:

Raj, Shammy;
Waduthanthri, Kosala D.;
Kuppan, Purushothaman;
Korbutt, Gregory S.;
Unsworth, Larry D.;
Pepper, Andrew R.

Publication type:

Article

Sex Differences in Maturation and Function of Neonatal Porcine Islets Upon Transplantation in Mice.

Published in:

Xenotransplantation, 2025, v. 32, n. 2, p. 1, doi. 10.1111/xen.70039

By:

Cuesta‐Gomez, Nerea;
Castro, Chelsea;
Rosko, Mandy;
Seeberger, Karen;
Korbutt, Gregory S.

Publication type:

Article

Heterogenous expression of endocrine and progenitor cells within the neonatal porcine pancreatic lobes–Implications for neonatal porcine islet xenotransplantation.

Published in:

Xenotransplantation, 2023, v. 30, n. 2, p. 1, doi. 10.1111/xen.12793

By:

Seeberger, Karen L;
Salama, Bassem F;
Kelly, Sandra;
Rosko, Mandy;
Castro, Chelsea;
DesAulniers, Jessica;
Korbutt, Gregory S

Publication type:

Article

Xenotransplantation of tannic acid‐encapsulated neonatal porcine islets decreases proinflammatory innate immune responses.

Published in:

Xenotransplantation, 2021, v. 28, n. 6, p. 1, doi. 10.1111/xen.12706

By:

Barra, Jessie M.;
Kozlovskaya, Veronika;
Kepple, Jessica D.;
Seeberger, Karen L.;
Kuppan, Purushothaman;
Hunter, Chad S.;
Korbutt, Gregory S.;
Kharlampieva, Eugenia;
Tse, Hubert M.

Publication type:

Article

Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation.

Published in:

Xenotransplantation, 2021, v. 28, n. 3, p. 1, doi. 10.1111/xen.12669

By:

Zammit, Nathan W.;
Seeberger, Karen L.;
Zamerli, Jad;
Walters, Stacey N.;
Lisowski, Leszek;
Korbutt, Gregory S.;
Grey, Shane T.

Publication type:

Article

Impact of donor and prolonged cold ischemia time of neonatal pig pancreas on neonatal pig islet transplant outcome.

Published in:

Xenotransplantation, 2021, v. 28, n. 2, p. 1, doi. 10.1111/xen.12663

By:

Huang, Wenlong;
Shimizu, Hirofumi;
Bianchi, John;
Matovinovic, Kaja;
Ayares, David L.;
Gotoh, Mitsukazu;
Korbutt, Gregory S.;
Rajotte, Ray V.;
Rayat, Gina R.

Publication type:

Article

Co‐transplantation of human adipose‐derived mesenchymal stem cells with neonatal porcine islets within a prevascularized subcutaneous space augments the xenograft function.

Published in:

Xenotransplantation, 2020, v. 27, n. 4, p. 1, doi. 10.1111/xen.12581

By:

Kuppan, Purushothaman;
Seeberger, Karen;
Kelly, Sandra;
Rosko, Mandy;
Adesida, Adetola;
Pepper, Andrew R.;
Korbutt, Gregory S.

Publication type:

Article

Fibrin supports subcutaneous neonatal porcine islet transplantation without the need for pre‐vascularization.

Published in:

Xenotransplantation, 2020, v. 27, n. 4, p. 1, doi. 10.1111/xen.12575

By:

Salama, Bassem F.;
Seeberger, Karen L.;
Korbutt, Gregory S.

Publication type:

Article

In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β‐cell function, and transcriptomes.

Published in:

Xenotransplantation, 2018, v. 25, n. 6, p. N.PAG, doi. 10.1111/xen.12432

By:

Smith, Kate E.;
Purvis, William G.;
Davis, Melissa A.;
Min, Catherine G.;
Cooksey, Amanda M.;
Weber, Craig S.;
Jandova, Jana;
Price, Nicholas D.;
Molano, Diana S.;
Stanton, James Brett;
Kelly, Amy C.;
Steyn, Leah V.;
Lynch, Ronald M.;
Limesand, Sean W.;
Alexander, Michael;
Lakey, Jonathan R. T.;
Seeberger, Karen;
Korbutt, Gregory S.;
Mueller, Kate R.;
Hering, Bernhard J.

Publication type:

Article

Justifying clinical trials for porcine islet xenotransplantation.

Published in:

Xenotransplantation, 2015, v. 22, n. 5, p. 336, doi. 10.1111/xen.12196

By:

Ellis, Cara E.;
Korbutt, Gregory S.

Publication type:

Article

Chapter 3: Pig islet product manufacturing and release testing.

Published in:

Xenotransplantation, 2009, v. 16, n. 4, p. 223, doi. 10.1111/j.1399-3089.2009.00542.x

By:

Korbutt, Gregory S.

Publication type:

Article

Executive summary.

Published in:

Xenotransplantation, 2009, v. 16, n. 4, p. 196, doi. 10.1111/j.1399-3089.2009.00547.x

By:

Hering, Bernhard J.;
Cooper, David K. C.;
Cozzi, Emanuele;
Schuurman, Henk-Jan;
Korbutt, Gregory S.;
Denner, Joachim;
O’Connell, Philip J.;
Vanderpool, Harold Y.;
Pierson III, Richard N.

Publication type:

Article

What type of islets should be used?

Published in:

Xenotransplantation, 2008, v. 15, n. 2, p. 81, doi. 10.1111/j.1399-3089.2008.00455.x

By:

Korbutt, Gregory S.

Publication type:

Article

Acute exposure to streptozotocin but not human proinflammatory cytokines impairs neonatal porcine islet insulin secretion in vitro but not in vivo.

Published in:

Xenotransplantation, 2007, v. 14, n. 6, p. 580, doi. 10.1111/j.1399-3089.2007.00427.x

By:

Harb, George;
Toreson, Jeff;
Dufour, Janette;
Korbutt, Gregory

Publication type:

Article

Delayed functional maturation of neonatal porcine islets in recipients under strict glycemic control.

Published in:

Xenotransplantation, 2007, v. 14, n. 4, p. 333, doi. 10.1111/j.1399-3089.2007.00414.x

By:

Kin, Tatsuya;
Korbutt, Gregory S.

Publication type:

Article

Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts.

Published in:

Xenotransplantation, 2006, v. 13, n. 6, p. 547, doi. 10.1111/j.1399-3089.2006.00349.x

By:

Kobayashi, Tsunehiro;
Harb, George;
Rajotte, Ray V.;
Korbutt, Gregory S.;
Mallett, Aaron G.;
Arefanian, Hossein;
Mok, Dereck;
Rayat, Gina R.

Publication type:

Article

Long-term survival of neonatal porcine Sertoli cells in non-immunosuppressed rats.

Published in:

Xenotransplantation, 2003, v. 10, n. 6, p. 577, doi. 10.1034/j.1399-3089.2003.00059.x

By:

Dufour, Jannette M.;
Rajotte, Ray V.;
Seeberger, Karen;
Kin, Tatsuya;
Korbutt, Gregory S.

Publication type:

Article

Neonatal pig pancreata as a source of insulin-producing tissue for xenotransplantation.

Published in:

Xenotransplantation, 1995, v. 2, n. 3, p. 159, doi. 10.1111/j.1399-3089.1995.tb00086.x

By:

Korbutt, Gregory S.;
Ao, Ziliang;
Warnock, Garth L.;
Rajotte, Ray V.

Publication type:

Article

Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages.

Published in:

Nature Biotechnology, 2004, v. 22, n. 9, p. 1115, doi. 10.1038/nbt1004

By:

Seaberg, Raewyn M.;
Smukler, Simon R.;
Kieffer, Timothy J.;
Enikolopov, Grigori;
Asghar, Zeenat;
Wheeler, Michael B.;
Korbutt, Gregory;
van der Kooy, Derek

Publication type:

Article

Bioartificial organs and acceptable risk.

Published in:

Nature Biotechnology, 1999, v. 17, n. 11, p. 1045, doi. 10.1038/14989

By:

Hunkeler, David;
Sun, Anthony M.;
Korbutt, Gregory S.;
Rajotte, Ray V.;
Gill, Ronald G.;
Calafiore, Riccardo;
Morel, Philippe

Publication type:

Article

Research ethics and stem cells.

Published in:

EMBO Reports, 2015, v. 16, n. 1, p. 2, doi. 10.15252/embr.201439819

By:

Caulfield, Timothy;
Kamenova, Kalina;
Ogbogu, Ubaka;
Zarzeczny, Amy;
Baltz, Jay;
Benjaminy, Shelly;
Cassar, Paul A;
Clark, Marianne;
Isasi, Rosario;
Knoppers, Bartha;
Knowles, Lori;
Korbutt, Gregory;
Lavery, James V;
Lomax, Geoffrey P;
Master, Zubin;
McDonald, Michael;
Preto, Nina;
Toews, Maeghan

Publication type:

Article

Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23673-0

By:

Karampelias, Christos;
Rezanejad, Habib;
Rosko, Mandy;
Duan, Likun;
Lu, Jing;
Pazzagli, Laura;
Bertolino, Philippe;
Cesta, Carolyn E.;
Liu, Xiaojing;
Korbutt, Gregory S.;
Andersson, Olov

Publication type:

Article

Treatment of Obesity and Diabetes in Mice by Transplant of Gut Cells Engineered to Produce Leptin.

Published in:

Molecular Therapy, 2008, v. 16, n. 6, p. 1138, doi. 10.1038/mt.2008.62

By:

Oosman, Sarah N.;
Lam, Ada W.;
Harb, George;
Unniappan, Suraj;
Lam, Ni T.;
Webber, Travis;
Bruch, Daniel;
Qiu-Xia Zhang;
Korbutt, Gregory S.;
Kieffer, Timothy J.

Publication type:

Article

Granzyme B: a natural born killer.

Published in:

Immunological Reviews, 2003, v. 193, n. 1, p. 31, doi. 10.1034/j.1600-065X.2003.00044.x

By:

Lord, Sarah J.;
Rajotte, Ray V.;
Korbutt, Gregory S.;
Bleackley, R. Chris

Publication type:

Article

Milrinone, dobutamine or epinephrine use in asphyxiated newborn pigs resuscitated with 100% oxygen.

Published in:

Intensive Care Medicine, 2010, v. 36, n. 6, p. 1058, doi. 10.1007/s00134-010-1820-x

By:

Joynt, Chloë;
Bigam, David L.;
Charrois, Gregory;
Jewell, Laurence D.;
Korbutt, Gregory;
Po-Yin Cheung

Publication type:

Article

Cardio-renal recovery of hypoxic newborn pigs after 18%, 21% and 100% reoxygenation.

Published in:

Intensive Care Medicine, 2008, v. 34, n. 6, p. 1114, doi. 10.1007/s00134-008-1008-9

By:

Cheung, Po-Yin;
Obaid, Laila;
Emara, Marwan;
Brierley, Yann;
Johnson, Scott T.;
Chan, Grace S.;
Jewell, Laurence;
Korbutt, Gregory;
Bigam, David L.

Publication type:

Article