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IN SILICO LIBRARY SCREENING TO FIND NOVEL ANTICANCER AGENT WITH CHEMOSENSITIZING PROPERTIES: FOCUS ON TARGETING ATAXIA TELANGIECTASIA AND Rad3 RELATED KINASE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2024, v. 93, n. 1, p. 68, doi. 10.31482/mmsl.2023.009
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- Article
A-agents, misleadingly known as "Novichoks": a narrative review.
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- Archives of Toxicology, 2023, v. 97, n. 10, p. 2587, doi. 10.1007/s00204-023-03571-8
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- Article
NEWS FROM EDITORIAL OFFICE OF MILITARY MEDICAL SCIENCE LETTERS VALID FROM 2024.
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- 2023
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- Publication type:
- Editorial
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity.
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- Archives of Toxicology, 2023, v. 97, n. 8, p. 2209, doi. 10.1007/s00204-023-03525-0
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- Article
Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9124, doi. 10.3390/ijms24119124
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- Article
Neurotoxicity evoked by organophosphates and available countermeasures.
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- Archives of Toxicology, 2023, v. 97, n. 1, p. 39, doi. 10.1007/s00204-022-03397-w
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- Article
Recent advances in dopamine D<sub>2</sub> receptor ligands in the treatment of neuropsychiatric disorders.
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- Medicinal Research Reviews, 2023, v. 43, n. 1, p. 55, doi. 10.1002/med.21923
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- Article
Chemical and Biological Threats, Hazard Potential and Countermeasures.
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- 2022
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- Publication type:
- Editorial
SYNTHESIS OF PURINE DERIVATIVES WITH ANTIMYCOBACTERIAL ACTIVITY.
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- 2022
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- Abstract
PHENOTHIAZINE-TACRINE HETERODIMERS: PURSUING MULTITARGET DIRECTED APPROACH IN ALZHEIMER'S DISEASE.
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- 2022
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- Abstract
SYNTHESIS OF PYRIMIDINE DERIVATIVES WITH ANTITUBERCULAR ACTIVITY.
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- 2022
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- Abstract
2-PROPARGAYLAMINO-NAPHTHOQUINONE DERIVATIVES AS MULTIPOTENT AGENTS FOR THE TREATMENT OFALZHEIMER'S DISEASE.
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- 2022
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- Abstract
TARGETING TACRINE HEPATOTOXICITY ASSOCIATED WITH THE CYP BIOTRANSFORMATION.
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- 2022
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- Abstract
TACRINE-SQUARAMIDE DERIVATIVES AS POTENT CHOLINESTERASE INHIBITORS.
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- 2022
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- Abstract
Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents.
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- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 844, doi. 10.3390/biom12060844
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- Article
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
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- Molecules, 2022, v. 27, n. 3, p. 1060, doi. 10.3390/molecules27031060
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- Article
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D 2 3,4-dihydroquinolin-2(1 H)-one Derivatives Related to Aripiprazole.
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- Biomolecules (2218-273X), 2021, v. 11, n. 9, p. 1262, doi. 10.3390/biom11091262
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- Article
Cholinesterase Research.
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- 2021
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- Editorial
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8308, doi. 10.3390/ijms22158308
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- Article
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3830, doi. 10.3390/ijms22083830
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- Article
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
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- Archives of Toxicology, 2021, v. 95, n. 3, p. 985, doi. 10.1007/s00204-021-02981-w
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- Article
Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity—In Vitro Study.
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- Molecular Neurobiology, 2021, v. 58, n. 3, p. 1102, doi. 10.1007/s12035-020-02172-1
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- Article
Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids.
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- Molecules, 2021, v. 26, n. 5, p. 1279, doi. 10.3390/molecules26051279
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- Article
Clinical Candidates Targeting the ATR–CHK1–WEE1 Axis in Cancer.
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- Cancers, 2021, v. 13, n. 4, p. 795, doi. 10.3390/cancers13040795
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- Article
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N -Methyl-d-Aspartate Receptor Antagonists.
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- Biomolecules (2218-273X), 2021, v. 11, n. 1, p. 3, doi. 10.3390/biom11010003
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- Article
The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75646-w
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- Article
Cover Image, Volume 40, Issue 5.
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- Medicinal Research Reviews, 2020, v. 40, n. 5, p. ii, doi. 10.1002/med.21616
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- Article
Recent advances with 5‐HT<sub>3</sub> modulators for neuropsychiatric and gastrointestinal disorders.
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- Medicinal Research Reviews, 2020, v. 40, n. 5, p. 1593, doi. 10.1002/med.21666
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- Article
Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase.
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- Biomolecules (2218-273X), 2020, v. 10, n. 5, p. 800, doi. 10.3390/biom10050800
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- Article
SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2020, v. 89, n. 2, p. 66, doi. 10.31482/mmsl.2020.005
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- Article
FARMAKOLOGICKÝ PROFIL DIZOCILPINU (MK-801) A MOŽNOSTI JEHO VYUŽITÍ VE ZVÍŘECÍCH MODELECH SCHIZOFRENIE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2019, v. 88, n. 4, p. 166, doi. 10.31482/mmsl.2019.019
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- Article
Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors.
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- Biomolecules (2218-273X), 2019, v. 9, n. 8, p. 379, doi. 10.3390/biom9080379
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- Article
PROFYLAKTIKA PROTI NERVOVĚ PARALYTICKÝM LÁTKÁM.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2019, v. 88, n. 3, p. 121, doi. 10.31482/mmsl.2019.016
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- Article
Orexin supplementation in narcolepsy treatment: A review.
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- Medicinal Research Reviews, 2019, v. 39, n. 3, p. 961, doi. 10.1002/med.21550
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- Article
Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease.
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- Molecules, 2019, v. 24, n. 7, p. 1307, doi. 10.3390/molecules24071307
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- Article
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier.
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- Molecules, 2019, v. 24, n. 7, p. 1340, doi. 10.3390/molecules24071340
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- Article
Oxime K203: a drug candidate for the treatment of tabun intoxication.
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- Archives of Toxicology, 2019, v. 93, n. 3, p. 673, doi. 10.1007/s00204-018-2377-7
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- Article
Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods.
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- Molecules, 2018, v. 23, n. 11, p. 2926, doi. 10.3390/molecules23112926
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- Article
DISCOVERY AND CHARACTERIZATION OF TACRINE/HUPRINE-TRYPTOPHAN HETERODIMERS AS NOVEL MULTIPOTENT COMPOUNDS AGAINST ALZHEIMER'S DISEASE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 71
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- Article
MOLECULAR MODELING IN SEARCH OF NEW, MULTI-TARGET LIGANDS AGAINST ALZHEIMER'S DISEASE. EXPLORING THE BIOCHEMICAL MULTIVERSE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 75
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- Publication type:
- Article
7-METHOXYDERIVATIVE OF TACRINE IS A 'FOOT-IN-THEDOOR' BLOCKER OF GluN1/GluN2 AND GluN1/GluN3 NMDA RECEPTORS.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 77
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- Publication type:
- Article
FACILE SYNTHESIS OF CYSTEINE-ACETYLCHOLINESTERASE TARGETED INSECTICIDES.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 91
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- Publication type:
- Article
7-MEOTA-DONEPEZIL HYBRIDS: POTENTIAL CHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 128
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- Publication type:
- Article
The New Acetylcholinesterase Inhibitors PC‐37 and PC‐48 (7‐Methoxytacrine‐Donepezil‐Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and <italic>In Vivo</italic> Formation of the Major Metabolites in Rats
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- Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 4, p. 373, doi. 10.1111/bcpt.12922
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- Publication type:
- Article
Melatonin jako základní stavební jednotka pro léčiva ve vztahu k neurodegenerativním poruchám.
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- Czech & Slovak Pharmacy / Česká a Slovenská Farmacie, 2018, v. 67, n. 2, p. 51
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- Publication type:
- Article
The influence of modulators of acetylcholinesterase on the resistance of mice against soman and on the effectiveness of antidotal treatment of soman poisoning in mice.
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- Journal of Applied Biomedicine, 2018, v. 16, n. 1, p. 10, doi. 10.1016/j.jab.2017.01.004
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- Article
Dose Dependent Prophylactic Efficacy of 6-Chlorotacrine in Soman-Poisoned Mice.
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- Acta Medica, 2017, v. 60, n. 4, p. 140, doi. 10.14712/18059694.2018.9
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- Article
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
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- Molecules, 2017, v. 22, n. 8, p. 1265, doi. 10.3390/molecules22081265
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- Publication type:
- Article
Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.
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- Molecules, 2017, v. 22, n. 6, p. 1006, doi. 10.3390/molecules22061006
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- Article
Inhibitors of Acetylcholinesterase Derived from 7-Methoxytacrine and Their Effects on the Choline Transporter CHT1.
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- Dementia & Geriatric Cognitive Disorders, 2017, v. 43, n. 1/2, p. 45, doi. 10.1159/000453256
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- Publication type:
- Article