Works by Koprich, James B.

Results: 28

Update on Molecular Imaging in Parkinson’s Disease.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 2, p. 330, doi. 10.1007/s12264-017-0202-6

By:

Liu, Zhen-Yang;
Liu, Feng-Tao;
Zuo, Chuan-Tao;
Koprich, James B.;
Wang, Jian

Publication type:

Article

Reproducibility of a Parkinsonism-related metabolic brain network in non-human primates: A descriptive pilot study with FDG PET.

Published in:

2015

By:

Ma, Yilong;
Johnston, Tom H.;
Peng, Shichun;
Zuo, Chuantao;
Koprich, James B.;
Fox, Susan H.;
Guan, Yihui;
Eidelberg, David;
Brotchie, Jonathan M.

Publication type:

journal article

The selective mu-opioid receptor antagonist adl5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in mptp-lesioned macaque model of Parkinson's disease.

Published in:

Movement Disorders, 2011, v. 26, n. 7, p. 1225, doi. 10.1002/mds.23631

By:

Koprich, James B.;
Fox, Susan H.;
Johnston, Tom H.;
Goodman, Allan;
Le Bourdonnec, Bertrand;
Dolle, Roland E.;
DeHaven, Robert N.;
DeHaven-Hudkins, Diane L.;
Little, Patrick J.;
Brotchie, Jonathan M.

Publication type:

Article

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06832-1

By:

Matschke, Lina A.;
Komadowski, Marlene A.;
Stöhr, Annette;
Lee, Bolam;
Henrich, Martin T.;
Griesbach, Markus;
Rinné, Susanne;
Geibl, Fanni F.;
Chiu, Wei-Hua;
Koprich, James B.;
Brotchie, Jonathan M.;
Kiper, Aytug K.;
Dolga, Amalia M.;
Oertel, Wolfgang H.;
Decher, Niels

Publication type:

Article

The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson's Disease.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 841, doi. 10.3390/cells9040841

By:

Titze-de-Almeida, Simoneide S.;
Soto-Sánchez, Cristina;
Fernandez, Eduardo;
Koprich, James B.;
Brotchie, Jonathan M.;
Titze-de-Almeida, Ricardo

Publication type:

Article

Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017698

By:

Koprich, James B.;
Johnston, Tom H.;
Huot, Philippe;
Reyes, M. Gabriela;
Espinosa, Maria;
Brotchie, Jonathan M.

Publication type:

Article

Nigrostriatal Dysfunction in Familial Alzheimer's Disease-Linked APPswe/PS1ΔE9 Transgenic Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 44, p. 10220, doi. 10.1523/JNEUROSCI.2773-05.2005

By:

Perez, Sylvia E.;
Lazarov, Orly;
Koprich, James B.;
Er-Yun Chen;
Rodriguez-Menendez, Virginia;
Lipton, Jack W.;
Sisodia, Sangram S.;
Mufson, Elliott J.

Publication type:

Article

KP544, a nerve growth factor amplifier: Pharmacokinetics, safety, and efficacy in the ratA preliminary report of part of this work was presented at the Abstracts of the Society for Neuroscience Meeting, New Orleans, LA, 2003.

Published in:

Drug Development Research, 2004, v. 62, n. 1, p. 60, doi. 10.1002/ddr.10384

By:

Thomas A. Krenitsky;
John Dillberger;
Elena Zotova;
Joseph C. Arezzo;
James B. Koprich;
Farzad Mortazavi;
Timothy A. Gates;
Gary L. Dunbar

Publication type:

Article

Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice.

Published in:

2020

By:

Shen, Yan;
Yu, Wen-Bo;
Shen, Bo;
Dong, Hui;
Zhao, Jue;
Tang, Yi-Lin;
Fan, Yun;
Yang, Yan-Fei;
Sun, Yi-Min;
Luo, Su-Shan;
Chen, Chen;
Liu, Feng-Tao;
Wu, Jian-Jun;
Xiao, Bao-Guo;
Yu, Huan;
Koprich, James B;
Huang, Zhi-Li;
Wang, Jian

Publication type:

journal article

Reply to "Can STN DBS protect both nigral somata and innervation of the striatum?".

Published in:

2017

By:

Koprich, James B.;
Brotchie, Jonathan M.;
Musacchio, Thomas;
Volkmann, Jens;
Ip, Chi Wang

Publication type:

Letter

Subthalamic nucleus deep brain stimulation is neuroprotective in the A53T α-synuclein Parkinson's disease rat model.

Published in:

2017

By:

Musacchio, Thomas;
Rebenstorff, Maike;
Fluri, Felix;
Brotchie, Jonathan M.;
Volkmann, Jens;
Koprich, James B.;
Ip, Chi Wang

Publication type:

journal article

Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson's disease.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02759-0

By:

Grotemeyer, Alexander;
Fischer, Judith F.;
Koprich, James B.;
Brotchie, Jonathan M.;
Blum, Robert;
Volkmann, Jens;
Ip, Chi Wang

Publication type:

Article

Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T-α-synuclein Parkinson's disease mice.

Published in:

Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-022-02685-7

By:

Badr, Mohammad;
McFleder, Rhonda L.;
Wu, Jingjing;
Knorr, Susanne;
Koprich, James B.;
Hünig, Thomas;
Brotchie, Jonathan M.;
Volkmann, Jens;
Lutz, Manfred B.;
Ip, Chi Wang

Publication type:

Article

AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0416-x

By:

Chi Wang Ip;
Klaus, Laura-Christin;
Karikari, Akua A.;
Visanji, Naomi P.;
Brotchie, Jonathan M.;
Lang, Anthony E.;
Volkmann, Jens;
Koprich, James B.

Publication type:

Article

Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0375-7

By:

Chi Wang Ip;
Isaias, Ioannis U.;
Kusche-Tekin, Burak B.;
Klein, Dennis;
Groh, Janos;
Knorr, Susanne;
Toyka, Klaus V.;
Volkmann, Jens;
O'Leary, Aet;
Reif, Andreas;
Higuchi, Takahiro;
Koprich, James B.;
Brotchie, Jonathan M.

Publication type:

Article

Towards a Non-Human Primate Model of Alpha-Synucleinopathy for Development of Therapeutics for Parkinson’s Disease: Optimization of AAV1/2 Delivery Parameters to Drive Sustained Expression of Alpha Synuclein and Dopaminergic Degeneration in Macaque.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167235

By:

Koprich, James B.;
Johnston, Tom H.;
Reyes, Gabriela;
Omana, Vanessa;
Brotchie, Jonathan M.

Publication type:

Article

Exosome markers of LRRK2 kinase inhibition.

Published in:

NPJ Parkinson's Disease, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41531-020-00138-7

By:

Wang, Shijie;
Kelly, Kaela;
Brotchie, Jonathan M.;
Koprich, James B.;
West, Andrew B.

Publication type:

Article

Use of catechol- O-methyltransferase inhibition to minimize L-3,4-dihydroxyphenylalanine-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque.

Published in:

European Journal of Neuroscience, 2013, v. 37, n. 5, p. 831, doi. 10.1111/ejn.12093

By:

Huot, Philippe;
Johnston, Tom H.;
Snoeren, Tessa;
Koprich, James B.;
Hill, Michael P.;
Fox, Susan H.;
Brotchie, Jonathan M.

Publication type:

Article

Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease.

Published in:

2008

By:

Koprich JB;
Reske-Nielsen C;
Mithal P;
Isacson O;
Koprich, James B;
Reske-Nielsen, Casper;
Mithal, Prabhakar;
Isacson, Ole

Publication type:

journal article

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease.

Published in:

Journal of Neuroinflammation, 2008, v. 5, p. 1, doi. 10.1186/1742-2094-5-8

By:

Koprich, James B.;
Reske-Nielsen, Casper;
Mithal, Prabhakar;
Isacson, Ole

Publication type:

Article

GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson's Disease.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42847-x

By:

Schneider, Jay S.;
Aras, Radha;
Williams, Courtney K.;
Koprich, James B.;
Brotchie, Jonathan M.;
Singh, Vikrant

Publication type:

Article

Brain-to-gut trafficking of alpha-synuclein by CD11c<sup>+</sup> cells in a mouse model of Parkinson's disease.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43224-z

By:

McFleder, Rhonda L.;
Makhotkina, Anastasiia;
Groh, Janos;
Keber, Ursula;
Imdahl, Fabian;
Peña Mosca, Josefina;
Peteranderl, Alina;
Wu, Jingjing;
Tabuchi, Sawako;
Hoffmann, Jan;
Karl, Ann-Kathrin;
Pagenstecher, Axel;
Vogel, Jörg;
Beilhack, Andreas;
Koprich, James B.;
Brotchie, Jonathan M.;
Saliba, Antoine-Emmanuel;
Volkmann, Jens;
Ip, Chi Wang

Publication type:

Article

Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-0894-0

By:

McKinnon, Chris;
De Snoo, Mitchell L.;
Gondard, Elise;
Neudorfer, Clemens;
Chau, Hien;
Ngana, Sophie G.;
O'Hara, Darren M.;
Brotchie, Jonathan M.;
Koprich, James B.;
Lozano, Andres M.;
Kalia, Lorraine V.;
Kalia, Suneil K.

Publication type:

Article

MOLECULAR NEURODEGENERATION.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 43, doi. 10.1186/1750-1326-5-43

By:

Koprich, James B.;
Johnston, Tom H.;
Reyes, M. Gabriela;
Xuan Sun;
Brotchie, Jonathan M.

Publication type:

Article

Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 19, p. 7190, doi. 10.1523/JNEUROSCI.1171-11.2011

By:

Huot, Philippe;
Johnston, Tom H.;
Lewis, Katie D.;
Koprich, James B.;
Reyes, M. Gabriela;
Fox, Susan H.;
Piggott, Matthew J.;
Brotchie, Jonathan M.

Publication type:

Article

The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 48, p. 16091, doi. 10.1523/JNEUROSCI.2400-10.2010

By:

Deleidi, Michela;
Hallett, Penelope J.;
Koprich, James B.;
Chee-Yeun Chung;
Isacson, Ole

Publication type:

Article

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 11, p. 3365, doi. 10.1523/JNEUROSCI.5427-08.2009

By:

Chee Yeun Chung;
Koprich, James B.;
Siddiqi, Hasan;
Isacson, Ole

Publication type:

Article

An Endogenous Serine/Threonine Protein Phosphatase Inhibitor, G-Substrate, Reduces Vulnerability in Models of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 31, p. 8314, doi. 10.1523/JNEUROSCI.1972-07.2007

By:

Chee Yeun Chung;
Koprich, James B.;
Endo, Endo;
Isacson, Ole

Publication type:

Article