Works by Kool, Marcel


Results: 169
    1
    2

    Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.

    Published in:
    NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00238-4
    By:
    • Williamson, Laura M.;
    • Rive, Craig M.;
    • Di Francesco, Daniela;
    • Titmuss, Emma;
    • Chun, Hye-Jung E.;
    • Brown, Scott D.;
    • Milne, Katy;
    • Pleasance, Erin;
    • Lee, Anna F.;
    • Yip, Stephen;
    • Rosenbaum, Daniel G.;
    • Hasselblatt, Martin;
    • Johann, Pascal D.;
    • Kool, Marcel;
    • Harvey, Melissa;
    • Dix, David;
    • Renouf, Daniel J.;
    • Holt, Robert A.;
    • Nelson, Brad H.;
    • Hirst, Martin
    Publication type:
    Article
    3

    Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.

    Published in:
    Advanced Science, 2021, v. 8, n. 23, p. 1, doi. 10.1002/advs.202101923
    By:
    • Huang, Yulun;
    • Qi, Lin;
    • Kogiso, Mari;
    • Du, Yuchen;
    • Braun, Frank K.;
    • Zhang, Huiyuan;
    • Huang, L. Frank;
    • Xiao, Sophie;
    • Teo, Wan‐Yee;
    • Lindsay, Holly;
    • Zhao, Sibo;
    • Baxter, Patricia;
    • Su, Jack M. F.;
    • Adesina, Adekunle;
    • Yang, Jianhua;
    • Brabetz, Sebastian;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Chintagumpala, Murali;
    • Perlaky, Laszlo
    Publication type:
    Article
    4

    Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles.

    Published in:
    Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0287-6
    By:
    • Hölsken, Annett;
    • Sill, Martin;
    • Merkle, Jessica;
    • Schweizer, Leonille;
    • Buchfelder, Michael;
    • Flitsch, Jörg;
    • Fahlbusch, Rudolf;
    • Metzler, Markus;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Capper, David;
    • Jones, David T. W.;
    • Buslei, Rolf
    Publication type:
    Article
    5

    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.

    Published in:
    Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
    By:
    • Ecker, Jonas;
    • Oehme, Ina;
    • Mazitschek, Ralph;
    • Korshunov, Andrey;
    • Kool, Marcel;
    • Hielscher, Thomas;
    • Kiss, Judit;
    • Selt, Florian;
    • Konrad, Carina;
    • Lodrini, Marco;
    • Deubzer, Hedwig E.;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
    6

    WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma.

    Published in:
    Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0174-y
    By:
    • Zhukova, Nataliya;
    • Ramaswamy, Vijay;
    • Remke, Marc;
    • Martin, Dianna;
    • Castelo-Branco, Pedro;
    • Zhang, Cindy;
    • Fraser, Michael;
    • Tse, Ken;
    • Poon, Raymond;
    • Shih, David;
    • Baskin, Berivan;
    • Ray, Peter;
    • Bouffet, Eric;
    • Dirks, Peter;
    • von Bueren, Andre;
    • Pfaff, Elke;
    • Korshunov, Andrey;
    • Jones, David;
    • Northcott, Paul;
    • Kool, Marcel
    Publication type:
    Article
    7
    8

    Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a "MEMMAT-like" Metronomic Antiangiogenic Approach.

    Published in:
    Cancers, 2022, v. 14, n. 20, p. 5128, doi. 10.3390/cancers14205128
    By:
    • Slavc, Irene;
    • Mayr, Lisa;
    • Stepien, Natalia;
    • Gojo, Johannes;
    • Aliotti Lippolis, Maria;
    • Azizi, Amedeo A.;
    • Chocholous, Monika;
    • Baumgartner, Alicia;
    • Hedrich, Cora S.;
    • Holm, Stefan;
    • Sehested, Astrid;
    • Leblond, Pierre;
    • Dieckmann, Karin;
    • Haberler, Christine;
    • Czech, Thomas;
    • Kool, Marcel;
    • Peyrl, Andreas
    Publication type:
    Article
    9
    10

    Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D.

    Published in:
    Nature Protocols, 2022, v. 17, n. 12, p. 3028, doi. 10.1038/s41596-022-00739-x
    By:
    • van Ineveld, Ravian L.;
    • Collot, Raphaël;
    • Román, Mario Barrera;
    • Pagliaro, Anna;
    • Bessler, Nils;
    • Ariese, Hendrikus C. R.;
    • Kleinnijenhuis, Michiel;
    • Kool, Marcel;
    • Alieva, Maria;
    • Chuva de Sousa Lopes, Susana M.;
    • Wehrens, Ellen J.;
    • Rios, Anne C.
    Publication type:
    Article
    12

    Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth.

    Published in:
    Molecular Oncology, 2021, v. 15, n. 2, p. 523, doi. 10.1002/1878-0261.12800
    By:
    • Miele, Evelina;
    • Po, Agnese;
    • Mastronuzzi, Angela;
    • Carai, Andrea;
    • Besharat, Zein Mersini;
    • Pediconi, Natalia;
    • Abballe, Luana;
    • Catanzaro, Giuseppina;
    • Sabato, Claudia;
    • De Smaele, Enrico;
    • Canettieri, Gianluca;
    • Di Marcotullio, Lucia;
    • Vacca, Alessandra;
    • Mai, Antonello;
    • Levrero, Massimo;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Giangaspero, Felice;
    • Locatelli, Franco;
    • Ferretti, Elisabetta
    Publication type:
    Article
    13
    14

    Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging.

    Published in:
    Brain Pathology, 2019, v. 29, n. 3, p. 325, doi. 10.1111/bpa.12664
    By:
    • Pagès, Mélanie;
    • Pajtler, Kristian W.;
    • Puget, Stéphanie;
    • Castel, David;
    • Boddaert, Nathalie;
    • Tauziède‐Espariat, Arnault;
    • Picot, Stéphanie;
    • Debily, Marie‐Anne;
    • Kool, Marcel;
    • Capper, David;
    • Sainte‐Rose, Christian;
    • Chrétien, Fabrice;
    • Pfister, Stefan M.;
    • Pietsch, Torsten;
    • Grill, Jacques;
    • Varlet, Pascale;
    • Andreiuolo, Felipe
    Publication type:
    Article
    15

    Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

    Published in:
    Brain Pathology, 2018, v. 28, n. 5, p. 656, doi. 10.1111/bpa.12566
    By:
    • Korshunov, Andrey;
    • Chavez, Lukas;
    • Sharma, Tanvi;
    • Ryzhova, Marina;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Capper, David;
    • Sturm, Dominik;
    • Kool, Marcel;
    • Habel, Antje;
    • Kleinschmidt‐DeMasters, Bette K.;
    • Rosenblum, Marc;
    • Absalyamova, Oksana;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Pfister, Stefan M.;
    • Jones, David T.W.;
    • Perry, Arie;
    • von Deimling, Andreas
    Publication type:
    Article
    16

    Papillary Tumor of the Pineal Region: A Distinct Molecular Entity.

    Published in:
    Brain Pathology, 2016, v. 26, n. 2, p. 199, doi. 10.1111/bpa.12282
    By:
    • Heim, Stephanie;
    • Sill, Martin;
    • Jones, David T.W.;
    • Vasiljevic, Alexandre;
    • Jouvet, Anne;
    • Fèvre‐Montange, Michelle;
    • Wesseling, Pieter;
    • Beschorner, Rudi;
    • Mittelbronn, Michel;
    • Kohlhof, Patricia;
    • Hovestadt, Volker;
    • Johann, Pascal;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Korshunov, Andrey;
    • Ruland, Vincent;
    • Sperveslage, Jan;
    • Thomas, Christian;
    • Witt, Hendrik;
    • Deimling, Andreas
    Publication type:
    Article
    17
    18

    Nestin Expression Identifies Ependymoma Patients with Poor Outcome.

    Published in:
    Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x
    By:
    • Milde, Till;
    • Hielscher, Thomas;
    • Witt, Hendrik;
    • Kool, Marcel;
    • Mack, Stephen C.;
    • Deubzer, Hedwig E.;
    • Oehme, Ina;
    • Lodrini, Marco;
    • Benner, Axel;
    • Taylor, Michael D.;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Korshunov, Andrey
    Publication type:
    Article
    19

    Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.

    Published in:
    British Journal of Cancer, 2024, v. 131, n. 4, p. 763, doi. 10.1038/s41416-024-02740-5
    By:
    • Seiboldt, Till;
    • Zeiser, Constantia;
    • Nguyen, Duy;
    • Celikyürekli, Simay;
    • Herter, Sonja;
    • Najafi, Sara;
    • Stroh-Dege, Alexandra;
    • Meulenbroeks, Chris;
    • Mack, Norman;
    • Salem-Altintas, Rabia;
    • Westermann, Frank;
    • Schlesner, Matthias;
    • Milde, Till;
    • Kool, Marcel;
    • Holland-Letz, Tim;
    • Vogler, Meike;
    • Peterziel, Heike;
    • Witt, Olaf;
    • Oehme, Ina
    Publication type:
    Article
    20
    21
    22
    23
    24

    Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 3, p. 527, doi. 10.1007/s00401-023-02608-7
    By:
    • Johann, Pascal D.;
    • Altendorf, Lea;
    • Efremova, Emma-Maria;
    • Holsten, Till;
    • Steinbügl, Mona;
    • Nemes, Karolina;
    • Eckhardt, Alicia;
    • Kresbach, Catena;
    • Bockmayr, Michael;
    • Koch, Arend;
    • Haberler, Christine;
    • Antonelli, Manila;
    • DeSisto, John;
    • Schuhmann, Martin U.;
    • Hauser, Peter;
    • Siebert, Reiner;
    • Bens, Susanne;
    • Kool, Marcel;
    • Green, Adam L.;
    • Hasselblatt, Martin
    Publication type:
    Article
    25
    26

    Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 1, p. 97, doi. 10.1007/s00401-022-02522-4
    By:
    • Mynarek, Martin;
    • Obrecht, Denise;
    • Sill, Martin;
    • Sturm, Dominik;
    • Kloth-Stachnau, Katja;
    • Selt, Florian;
    • Ecker, Jonas;
    • von Hoff, Katja;
    • Juhnke, Björn-Ole;
    • Goschzik, Tobias;
    • Pietsch, Torsten;
    • Bockmayr, Michael;
    • Kool, Marcel;
    • von Deimling, Andreas;
    • Witt, Olaf;
    • Schüller, Ulrich;
    • Benesch, Martin;
    • Gerber, Nicolas U.;
    • Sahm, Felix;
    • Jones, David T. W.
    Publication type:
    Article
    27
    28
    29
    30

    Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 827, doi. 10.1007/s00401-021-02356-6
    By:
    • Sievers, Philipp;
    • Henneken, Sophie C.;
    • Blume, Christina;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Okonechnikov, Konstantin;
    • Reuss, David E.;
    • Benzel, Julia;
    • Maaß, Kendra K.;
    • Kool, Marcel;
    • Sturm, Dominik;
    • Zheng, Tuyu;
    • Ghasemi, David R.;
    • Kohlhof-Meinecke, Patricia;
    • Cruz, Ofelia;
    • Suñol, Mariona;
    • Lavarino, Cinzia;
    • Ruf, Viktoria;
    • Boldt, Henning B.
    Publication type:
    Article
    31

    Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 2, p. 361, doi. 10.1007/s00401-021-02328-w
    By:
    • Pathak, Rajiv;
    • Zin, Francesca;
    • Thomas, Christian;
    • Bens, Susanne;
    • Gayden, Tenzin;
    • Karamchandani, Jason;
    • Dudley, Roy W.;
    • Nemes, Karolina;
    • Johann, Pascal D.;
    • Oyen, Florian;
    • Kordes, Uwe;
    • Jabado, Nada;
    • Siebert, Reiner;
    • Paulus, Werner;
    • Kool, Marcel;
    • Frühwald, Michael C.;
    • Albrecht, Steffen;
    • Kalpana, Ganjam V.;
    • Hasselblatt, Martin
    Publication type:
    Article
    32

    Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.

    Published in:
    Acta Neuropathologica, 2021, v. 141, n. 2, p. 291, doi. 10.1007/s00401-020-02250-7
    By:
    • Holdhof, Dörthe;
    • Johann, Pascal D.;
    • Spohn, Michael;
    • Bockmayr, Michael;
    • Safaei, Sepehr;
    • Joshi, Piyush;
    • Masliah-Planchon, Julien;
    • Ho, Ben;
    • Andrianteranagna, Mamy;
    • Bourdeaut, Franck;
    • Huang, Annie;
    • Kool, Marcel;
    • Upadhyaya, Santhosh A.;
    • Bendel, Anne E.;
    • Indenbirken, Daniela;
    • Foulkes, William D.;
    • Bush, Jonathan W.;
    • Creytens, David;
    • Kordes, Uwe;
    • Frühwald, Michael C.
    Publication type:
    Article
    33

    ETMR: a tumor entity in its infancy.

    Published in:
    Acta Neuropathologica, 2020, v. 140, n. 3, p. 249, doi. 10.1007/s00401-020-02182-2
    By:
    • Lambo, Sander;
    • von Hoff, Katja;
    • Korshunov, Andrey;
    • Pfister, Stefan M.;
    • Kool, Marcel
    Publication type:
    Article
    34

    Molecular characterization of histopathological ependymoma variants.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 2, p. 305, doi. 10.1007/s00401-019-02090-0
    By:
    • Neumann, Julia E.;
    • Spohn, Michael;
    • Obrecht, Denise;
    • Mynarek, Martin;
    • Thomas, Christian;
    • Hasselblatt, Martin;
    • Dorostkar, Mario M.;
    • Wefers, Annika K.;
    • Frank, Stephan;
    • Monoranu, Camelia-Maria;
    • Koch, Arend;
    • Witt, Hendrik;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Rutkowski, Stefan;
    • Glatzel, Markus;
    • Schüller, Ulrich
    Publication type:
    Article
    35

    Molecular progression of SHH-activated medulloblastomas.

    Published in:
    2019
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Schrimpf, Daniel;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Kool, Marcel
    Publication type:
    Letter
    36

    RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 275, doi. 10.1007/s00401-019-02021-z
    By:
    • Wirthschaft, Peter;
    • Bode, Julia;
    • Soni, Himanshu;
    • Dietrich, Fabio;
    • Krüwel, Thomas;
    • Fischer, Bernd;
    • Knobbe-Thomsen, Christiane B.;
    • Rossetti, Giulia;
    • Hentschel, Andreas;
    • Mack, Norman;
    • Schönig, Kai;
    • Breckwoldt, Michael O.;
    • Schmandke, André;
    • Pusch, Stefan;
    • Medenbach, Jan;
    • Bendszus, Martin;
    • Schwab, Martin E.;
    • von Deimling, Andreas;
    • Kool, Marcel;
    • Herold-Mende, Christel
    Publication type:
    Article
    37

    Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 309, doi. 10.1007/s00401-019-02020-0
    By:
    • Sharma, Tanvi;
    • Schwalbe, Edward C.;
    • Williamson, Daniel;
    • Sill, Martin;
    • Hovestadt, Volker;
    • Mynarek, Martin;
    • Rutkowski, Stefan;
    • Robinson, Giles W.;
    • Gajjar, Amar;
    • Cavalli, Florence;
    • Ramaswamy, Vijay;
    • Taylor, Michael D.;
    • Lindsey, Janet C.;
    • Hill, Rebecca M.;
    • Jäger, Natalie;
    • Korshunov, Andrey;
    • Hicks, Debbie;
    • Bailey, Simon;
    • Kool, Marcel;
    • Chavez, Lukas
    Publication type:
    Article
    38

    TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 4, p. 657, doi. 10.1007/s00401-019-01982-5
    By:
    • Hellwig, Malte;
    • Holdhof, Dörthe;
    • Niesen, Judith;
    • Schoof, Melanie;
    • Schüller, Ulrich;
    • Bockmayr, Michael;
    • Kool, Marcel;
    • Kraus, Cornelia;
    • Zweier, Christiane;
    • Holmberg, Dan;
    • Spohn, Michael;
    • Ahlfeld, Julia;
    • Kitowski, Annabel;
    • Ohli, Jasmin;
    • Lauffer, Marlen C.;
    • Merk, Daniel J.;
    • Harrison, Luke;
    • Neumann, Julia E.
    Publication type:
    Article
    39

    Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Sahm, Felix;
    • von Deimling, Andreas;
    • Korshunov, Andrey;
    • Jones, David T. W.;
    • Okonechnikov, Konstantin;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Lichter, Peter;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey
    Publication type:
    Article
    40

    Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1.

    Published in:
    2019
    By:
    • Thomas, Christian;
    • Knerlich-Lukoschus, Friederike;
    • Reinhard, Harald;
    • Johann, Pascal D.;
    • Sturm, Dominik;
    • Sahm, Felix;
    • Bens, Susanne;
    • Vogt, Julia;
    • Nemes, Karolina;
    • Oyen, Florian;
    • Kordes, Uwe;
    • Siebert, Reiner;
    • Schneppenheim, Reinhard;
    • Messing-Jünger, Martina;
    • Pietsch, Torsten;
    • von Deimling, Andreas;
    • Paulus, Werner;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Frühwald, Michael C.
    Publication type:
    Case Study
    41

    ETMR-like infantile cerebellar embryonal tumors in the extended morphologic spectrum of DICER1-related tumors.

    Published in:
    2019
    By:
    • Uro-Coste, Emmanuelle;
    • Masliah-Planchon, Julien;
    • Siegfried, Aurore;
    • Blanluet, Maud;
    • Lambo, Sander;
    • Kool, Marcel;
    • Roujeau, Thomas;
    • Boetto, Sergio;
    • Palenzuela, Gilles;
    • Bertozzi, Anne-Isabelle;
    • Gambart, Marion;
    • Coupier, Isabelle;
    • Oliver-Petit, Isabelle;
    • Golmard, Lisa;
    • Julia, Sophie;
    • Savagner, Fréderique;
    • Mohand-Oumoussa, Badreddine;
    • Tauziede-Espariat, Arnault;
    • Delisle, Marie-Bernadette;
    • Figarella-Branger, Dominique
    Publication type:
    Case Study
    42

    Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 339, doi. 10.1007/s00401-018-1883-2
    By:
    • Solomon, David A.;
    • Korshunov, Andrey;
    • Sill, Martin;
    • Jones, David T. W.;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Fan, Xuemo;
    • Bannykh, Serguei;
    • Hu, Jethro;
    • Danielpour, Moise;
    • Li, Rong;
    • Johnston, James;
    • Cham, Elaine;
    • Cooney, Tabitha;
    • Sun, Peter P.;
    • Oberheim Bush, Nancy Ann;
    • McDermott, Michael;
    • Van Ziffle, Jessica;
    • Onodera, Courtney;
    • Grenert, James P.
    Publication type:
    Article
    43

    Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 303, doi. 10.1007/s00401-018-1840-0
    By:
    • Korshunov, Andrey;
    • Sahm, Felix;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel
    Publication type:
    Article
    44

    Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

    Published in:
    Acta Neuropathologica, 2018, v. 135, n. 4, p. 635, doi. 10.1007/s00401-018-1819-x
    By:
    • Iorgulescu, J. Bryan;
    • Van Ziffle, Jessica;
    • Stevers, Meredith;
    • Grenert, James P.;
    • Bastian, Boris C.;
    • Chavez, Lukas;
    • Stichel, Damian;
    • Buchhalter, Ivo;
    • Samuel, David;
    • Nicolaides, Theodore;
    • Banerjee, Anuradha;
    • Mueller, Sabine;
    • Gupta, Nalin;
    • Tihan, Tarik;
    • Bollen, Andrew W.;
    • Northcott, Paul A.;
    • Kool, Marcel;
    • Pfister, Stefan;
    • Korshunov, Andrey;
    • Perry, Arie
    Publication type:
    Article
    45
    47

    Long-term outcome of the Milano-hyperfractionated accelerated radiotherapy strategy for high-risk medulloblastoma, including the impact of molecular subtype.

    Published in:
    Neuro-Oncology, 2025, v. 27, n. 1, p. 209, doi. 10.1093/neuonc/noae189
    By:
    • Massimino, Maura;
    • Barretta, Francesco;
    • Dossena, Chiara;
    • Minasi, Simone;
    • Buttarelli, Francesca Romana;
    • Biassoni, Veronica;
    • Oriani, Matilde;
    • Schiavello, Elisabetta;
    • Ficorilli, Marica;
    • Nigro, Olga;
    • Pollo, Bianca;
    • Antonelli, Manila;
    • Donofrio, Vittoria;
    • Maggioni, Marco;
    • Kool, Marcel;
    • Pecori, Emilia;
    • Vennarini, Sabina;
    • Giangaspero, Felice;
    • Gianno, Francesca;
    • Erbetta, Alessandra
    Publication type:
    Article
    48
    49

    Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03339-0
    By:
    • Infante, Paola;
    • Faedda, Roberta;
    • Bernardi, Flavia;
    • Bufalier, Francesca;
    • Severini, Ludovica Lospinoso;
    • Alfonsi, Romina;
    • Mazzà, Daniela;
    • Siler, Mariangela;
    • Coni, Sonia;
    • Po, Agnese;
    • Petroni, Marialaura;
    • Ferretti, Elisabetta;
    • Mori, Mattia;
    • De Smaele, Enrico;
    • Canettieri, Gianluca;
    • Capalbo, Carlo;
    • Maroder, Marella;
    • Screpanti, Isabella;
    • Kool, Marcel;
    • Pfister, Stefan M.
    Publication type:
    Article
    50

    Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.

    Published in:
    Cell Death & Disease, 2022, v. 13, n. 9, p. 1, doi. 10.1038/s41419-022-05243-4
    By:
    • Blümel, Lena;
    • Qin, Nan;
    • Berlandi, Johannes;
    • Paisana, Eunice;
    • Cascão, Rita;
    • Custódia, Carlos;
    • Pauck, David;
    • Picard, Daniel;
    • Langini, Maike;
    • Stühler, Kai;
    • Meyer, Frauke-Dorothee;
    • Göbbels, Sarah;
    • Malzkorn, Bastian;
    • Liebau, Max C.;
    • Barata, João T.;
    • Jeibmann, Astrid;
    • Kerl, Kornelius;
    • Erkek, Serap;
    • Kool, Marcel;
    • Pfister, Stefan M.
    Publication type:
    Article