Works by Kool, Jeroen
Results: 57
Activity assay based on the immobilized enzyme kallikrein and mass spectrometry.
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- Frontiers in Analytical Science, 2022, p. 1, doi. 10.3389/frans.2022.1018115
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- Article
Author Correction: Using organ-on-a-chip technology to study haemorrhagic activities of snake venoms on endothelial tubules.
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- 2024
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- Correction Notice
Using organ-on-a-chip technology to study haemorrhagic activities of snake venoms on endothelial tubules.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60282-5
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- Article
A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite.
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- Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.00848
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- Article
The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms.
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- Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0039-1
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- Article
Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins.
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- Biomedicines, 2020, v. 8, n. 9, p. 297, doi. 10.3390/biomedicines8090297
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- Article
Varespladib Inhibits the Phospholipase A2 and Coagulopathic Activities of Venom Components from Hemotoxic Snakes.
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- Biomedicines, 2020, v. 8, n. 6, p. 165, doi. 10.3390/biomedicines8060165
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- Article
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms.
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- PLoS Neglected Tropical Diseases, 2023, v. 17, n. 8, p. 1, doi. 10.1371/journal.pntd.0011564
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- Article
In vitro metabolism of cathinone positional isomers: does sex matter?
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- Analytical & Bioanalytical Chemistry, 2023, v. 415, n. 22, p. 5403, doi. 10.1007/s00216-023-04815-3
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- Article
Affinity profiling of monoclonal antibody and antibody-drug-conjugate preparations by coupled liquid chromatography-surface plasmon resonance biosensing.
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- Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 30, p. 7837, doi. 10.1007/s00216-018-1414-y
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- Article
Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1331224
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- Article
Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1328950
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- Article
The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32174-7
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- Article
Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise.
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- British Journal of Haematology, 2017, v. 177, n. 6, p. 947, doi. 10.1111/bjh.14591
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- Article
A high-throughput sample preparation method for cellular proteomics using 96-well filter plates.
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- Proteomics, 2013, v. 13, n. 20, p. 2980, doi. 10.1002/pmic.201300080
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- Article
Suction blister fluid as potential body fluid for biomarker proteins.
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- Proteomics, 2007, v. 7, n. 20, p. 3638, doi. 10.1002/pmic.200600938
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- Article
Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06019-6
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- Article
Aligning Post-Column ESI-MS, MALDI-MS, and Coagulation Bioassay Data of Naja spp., Ophiophagus hannah , and Pseudonaja textillis Venoms Chromatographically to Assess MALDI-MS and ESI-MS Complementarity with Correlation of Bioactive Toxins to Mass Spectrometric Data
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- Toxins, 2024, v. 16, n. 9, p. 379, doi. 10.3390/toxins16090379
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- Article
Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins.
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- Toxins, 2024, v. 16, n. 8, p. 370, doi. 10.3390/toxins16080370
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- Article
Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying.
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- Toxins, 2024, v. 16, n. 7, p. 300, doi. 10.3390/toxins16070300
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- Article
Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography–Mass Spectrometry Coupled with Bioinformatic Tools.
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- Toxins, 2024, v. 16, n. 4, p. 181, doi. 10.3390/toxins16040181
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- Article
Analytical Size Exclusion Chromatography Coupled with Mass Spectrometry in Parallel with High-Throughput Venomics and Bioassaying for Venom Profiling.
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- Toxins, 2023, v. 15, n. 9, p. 552, doi. 10.3390/toxins15090552
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Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins.
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- Toxins, 2023, v. 15, n. 4, p. 294, doi. 10.3390/toxins15040294
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- Article
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools.
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- Toxins, 2023, v. 15, n. 2, p. 161, doi. 10.3390/toxins15020161
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- Article
Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans (Oxyuranus spp.) and Brown Snakes (Pseudonaja spp.).
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- Toxins, 2023, v. 15, n. 1, p. 74, doi. 10.3390/toxins15010074
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- Article
A Combined Bioassay and Nanofractionation Approach to Investigate the Anticoagulant Toxins of Mamba and Cobra Venoms and Their Inhibition by Varespladib.
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- Toxins, 2022, v. 14, n. 11, p. 736, doi. 10.3390/toxins14110736
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- Article
Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib.
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- Toxins, 2021, v. 13, n. 5, p. 302, doi. 10.3390/toxins13050302
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- Article
Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics.
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- Toxins, 2020, v. 12, n. 1, p. 53, doi. 10.3390/toxins12010053
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- Article
Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms.
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- Toxins, 2017, v. 9, n. 12, p. 382, doi. 10.3390/toxins9120382
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- Article
High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 4, p. 1, doi. 10.1371/journal.pntd.0007802
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- Article
PHARMACEUTICAL PROPERTIES OF VENOM TOXINS AND THEIR POTENTIAL IN DRUG DISCOVERY.
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- Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2016, v. 27, n. 1, p. 1, doi. 10.14499/indonesianjpharm27iss1pp1
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- Article
Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates.
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- Biology (2079-7737), 2023, v. 12, n. 6, p. 765, doi. 10.3390/biology12060765
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- Article
Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail.
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- Biology (2079-7737), 2014, v. 3, n. 1, p. 139, doi. 10.3390/biology3010139
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- Article
Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite.
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- Science Translational Medicine, 2020, v. 12, n. 542, p. 1, doi. 10.1126/scitranslmed.aay8314
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- Article
Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
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- Toxins, 2015, v. 7, n. 7, p. 2336, doi. 10.3390/toxins7072336
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- Article
Acetylcholine-Binding Protein Affinity Profiling of Neurotoxins in Snake Venoms with Parallel Toxin Identification.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16769, doi. 10.3390/ijms242316769
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- Article
An on-line post-column detection system for the detection of reactive-oxygen-species-producing compounds and antioxidants in mixtures.
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- Analytical & Bioanalytical Chemistry, 2007, v. 388, n. 4, p. 871, doi. 10.1007/s00216-007-1296-x
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- Article
High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening.
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- Molecules, 2022, v. 27, n. 20, p. 6923, doi. 10.3390/molecules27206923
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- Article
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
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- 2024
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- Publication type:
- Correction Notice
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43510-w
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- Article
Liquid chromatographic nanofractionation with parallel mass spectrometric detection for the screening of plasmin inhibitors and (metallo)proteinases in snake venoms.
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- Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 23, p. 5751, doi. 10.1007/s00216-018-1253-x
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- Article
Rapid screening and identification of ACE inhibitors in snake venoms using at-line nanofractionation LC-MS.
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- Analytical & Bioanalytical Chemistry, 2017, v. 409, n. 25, p. 5987, doi. 10.1007/s00216-017-0531-3
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- Article
Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment.
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- Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 23, p. 7067, doi. 10.1007/s00216-015-8867-z
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- Article
On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.
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- Analytical & Bioanalytical Chemistry, 2012, v. 403, n. 2, p. 367, doi. 10.1007/s00216-011-5663-2
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Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods.
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- Analytical & Bioanalytical Chemistry, 2011, v. 401, n. 4, p. 1109, doi. 10.1007/s00216-011-5207-9
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- Article
Recent developments in protein-ligand affinity mass spectrometry.
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- Analytical & Bioanalytical Chemistry, 2011, v. 399, n. 8, p. 2669, doi. 10.1007/s00216-010-4350-z
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- Article
Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures.
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- Analytical & Bioanalytical Chemistry, 2011, v. 399, n. 8, p. 2655, doi. 10.1007/s00216-010-4406-0
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- Article
Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays.
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- Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 7/8, p. 3023, doi. 10.1007/s00216-010-4210-x
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- Article
Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.
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- Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 4, p. 1771, doi. 10.1007/s00216-010-4087-8
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- Article
Targeted LC–MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA.
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- Analytical & Bioanalytical Chemistry, 2010, v. 397, n. 2, p. 665, doi. 10.1007/s00216-010-3575-1
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- Article