Works matching AU Kontaridis, Maria I.

Results: 24

SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49978-4

By:

Chouhan, Surbhi;
Sridaran, Dhivya;
Weimholt, Cody;
Luo, Jingqin;
Li, Tiandao;
Hodgson, Myles C.;
Santos, Luana N.;
Le Sommer, Samantha;
Fang, Bin;
Koomen, John M.;
Seeliger, Markus;
Qu, Cheng-Kui;
Yart, Armelle;
Kontaridis, Maria I.;
Mahajan, Kiran;
Mahajan, Nupam P.

Publication type:

Article

Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.

Published in:

2016

By:

Lauriol, Jessica;
Cabrera, Janel R.;
Roy, Ashbeel;
Keith, Kimberly;
Hough, Sara M.;
Damilano, Federico;
Wang, Bonnie;
Segarra, Gabriel C.;
Flessa, Meaghan E.;
Miller, Lauren E.;
Das, Saumya;
Bronson, Roderick;
Kyu-Ho Lee;
Kontaridis, Maria I.;
Lee, Kyu-Ho

Publication type:

journal article

Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.

Published in:

2016

By:

Jianxun Wang;
Masayuki Mizui;
Li-Fan Zeng;
Bronson, Roderick;
Finnell, Michele;
Terhorst, Cox;
Kyttaris, Vasileios C.;
Tsokos, George C.;
Zhong-Yin Zhang;
Kontaridis, Maria I.;
Wang, Jianxun;
Mizui, Masayuki;
Zeng, Li-Fan;
Zhang, Zhong-Yin

Publication type:

journal article

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.

Published in:

2011

By:

Marin, Talita M.;
Keith, Kimberly;
Davies, Benjamin;
Conner, David A.;
Guha, Prajna;
Kalaitzidis, Demetrios;
Xue Wu;
Lauriol, Jessica;
Bo Wang;
Bauer, Michael;
Bronson, Roderick;
Franchini, Kleber G.;
Neel, Benjamin G.;
Kontaridis, Maria I.;
Wu, Xue;
Wang, Bo

Publication type:

journal article

YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6649, doi. 10.3390/ijms22136649

By:

Gao, Yunan;
Sun, Yan;
Ercan-Sencicek, Adife Gulhan;
King, Justin S.;
Akerberg, Brynn N.;
Ma, Qing;
Kontaridis, Maria I.;
Pu, William T.;
Lin, Zhiqiang

Publication type:

Article

In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178905

By:

Wang, Jianxun;
Chandrasekhar, Vasanth;
Abbadessa, Giovanni;
Yu, Yi;
Schwartz, Brian;
Kontaridis, Maria I.

Publication type:

Article

Genetic and Phenotypic Analysis of Patients with Mucopolysaccharidosis type IIIB Co-morbid with Autism Spectrum Disorder.

Published in:

Gazi Medical Journal, 2024, v. 35, p. 6

By:

Ercan-Şençiçek, A. Gülhan;
Barak, Tanyeri;
Rai, Devendra K.;
Kaymakçalan, Hande;
Kaya, İlyas;
Erbilgin, Seda;
Uytun, Merve Çıkılı;
Öztop, Didem;
Gümüş, Hakan;
Per, Hüseyin;
Ceylaner, Serdar;
Aromolaran, Kelly;
Bozkurt, İçten;
Mishra-Gorur, Ketu;
Kontaridis, Maria I.;
Bilgüvar, Kaya;
Kılınçaslan, Ayşe;
Çağlayan, Ahmet Okay;
Erson-Omay, E. Zeynep;
Günel, Murat

Publication type:

Article

Cardio-rheumatology: the cardiovascular, pharmacological, and surgical risks associated with rheumatological diseases in women.

Published in:

Canadian Journal of Physiology & Pharmacology, 2024, v. 102, n. 9, p. 511, doi. 10.1139/cjpp-2023-0420

By:

Sommer, Samantha Le;
Kontaridis, Maria I.

Publication type:

Article

PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 15, p. 2874, doi. 10.1128/MCB.00135-14

By:

Overman, Jeroen Paardekooper;
Jae-Sung Yi;
Bonetti, Monica;
Soulsby, Matthew;
Preisinger, Christian;
Stokes, Matthew P.;
Li Hui;
Silva, Jeffrey C.;
Overvoorde, John;
Giansanti, Piero;
Heck, Albert J. R.;
Kontaridis, Maria I.;
den Hertog, Jeroen;
Bennett, Anton M.

Publication type:

Article

The seventh international RASopathies symposium: Pathways to a cure—expanding knowledge, enhancing research, and therapeutic discovery.

Published in:

American Journal of Medical Genetics. Part A, 2022, v. 188, n. 6, p. 1915, doi. 10.1002/ajmg.a.62716

By:

Kontaridis, Maria I.;
Roberts, Amy E.;
Schill, Lisa;
Schoyer, Lisa;
Stronach, Beth;
Andelfinger, Gregor;
Aoki, Yoko;
Axelrad, Marni E.;
Bakker, Annette;
Bennett, Anton M.;
Broniscer, Alberto;
Castel, Pau;
Chang, Caitlin A.;
Cyganek, Lukas;
Das, Tirtha K.;
den Hertog, Jeroen;
Galperin, Emilia;
Garg, Shruti;
Gelb, Bruce D.;
Gordon, Kristiana

Publication type:

Article

Rapidly progressive hypertrophic cardiomyopathy in an infant with Noonan syndrome with multiple lentigines: Palliative treatment with a rapamycin analog.

Published in:

American Journal of Medical Genetics. Part A, 2015, v. 167A, n. 4, p. 744, doi. 10.1002/ajmg.a.36982

By:

Hahn, Andreas;
Lauriol, Jessica;
Thul, Josef;
Behnke‐Hall, Kachina;
Logeswaran, Tushiha;
Schänzer, Anne;
Böğürcü, Nuray;
Garvalov, Boyan K.;
Zenker, Martin;
Gelb, Bruce D.;
von Gerlach, Susanne;
Kandolf, Reinhard;
Kontaridis, Maria I.;
Schranz, Dietmar

Publication type:

Article

Stops along the RAS pathway in human genetic disease.

Published in:

Nature Medicine, 2006, v. 12, n. 3, p. 283, doi. 10.1038/nm0306-283

By:

Bentires-Alj, Mohamed;
Kontaridis, Maria I.;
Neel, Benjamin G.

Publication type:

Article

Biomimetic Nanomaterials for the Immunomodulation of the Cardiosplenic Axis Postmyocardial Infarction.

Published in:

Advanced Materials, 2024, v. 36, n. 8, p. 1, doi. 10.1002/adma.202304615

By:

Bose, Rajendran JC;
Kessinger, Chase W.;
Dhammu, Tajinder;
Singh, Toolika;
Shealy, Miller W.;
Ha, Khanh;
Collandra, Rena;
Himbert, Sebastian;
Garcia, Fernando J.;
Oleinik, Natalia;
Xu, Bing;
Vikas;
Kontaridis, Maria I.;
Rheinstädter, Maikel C.;
Ogretmen, Besim;
Menick, Donald R.;
McCarthy, Jason R.

Publication type:

Article

Lineage‐Specific Mesenchymal Stromal Cells Derived from Human iPSCs Showed Distinct Patterns in Transcriptomic Profile and Extracellular Vesicle Production.

Published in:

Advanced Science, 2024, v. 11, n. 28, p. 1, doi. 10.1002/advs.202308975

By:

Winston, Tackla;
Song, Yuanhui;
Shi, Huaiyu;
Yang, Junhui;
Alsudais, Munther;
Kontaridis, Maria I.;
Wu, Yaoying;
Gaborski, Thomas R.;
Meng, Qinghe;
Cooney, Robert N.;
Ma, Zhen

Publication type:

Article

Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs (Adv. Sci. 17/2022)

Published in:

Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202270109

By:

Li, Guoping;
Manning, Aidan C.;
Bagi, Alex;
Yang, Xinyu;
Gokulnath, Priyanka;
Spanos, Michail;
Howard, Jonathan;
Chan, Patricia P.;
Sweeney, Thadryan;
Kitchen, Robert;
Li, Haobo;
Laurent, Brice D.;
Aranki, Sary F.;
Kontaridis, Maria I.;
Laurent, Louise C.;
Van Keuren‐Jensen, Kendall;
Muehlschlegel, Jochen;
Lowe, Todd M.;
Das, Saumya

Publication type:

Article

Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs (Adv. Sci. 17/2022).

Published in:

Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202200829

By:

Li, Guoping;
Manning, Aidan C.;
Bagi, Alex;
Yang, Xinyu;
Gokulnath, Priyanka;
Spanos, Michail;
Howard, Jonathan;
Chan, Patricia P.;
Sweeney, Thadryan;
Kitchen, Robert;
Li, Haobo;
Laurent, Brice D.;
Aranki, Sary F.;
Kontaridis, Maria I.;
Laurent, Louise C.;
Van Keuren‐Jensen, Kendall;
Muehlschlegel, Jochen;
Lowe, Todd M.;
Das, Saumya

Publication type:

Article

Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs.

Published in:

Advanced Science, 2022, v. 9, n. 17, p. 1, doi. 10.1002/advs.202200829

By:

Li, Guoping;
Manning, Aidan C.;
Bagi, Alex;
Yang, Xinyu;
Gokulnath, Priyanka;
Spanos, Michail;
Howard, Jonathan;
Chan, Patricia P.;
Sweeney, Thadryan;
Kitchen, Robert;
Li, Haobo;
Laurent, Brice D.;
Aranki, Sary F.;
Kontaridis, Maria I.;
Laurent, Louise C.;
Van Keuren‐Jensen, Kendall;
Muehlschlegel, Jochen;
Lowe, Todd M.;
Das, Saumya

Publication type:

Article

Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.

Published in:

Science Signaling, 2018, v. 11, n. 522, p. 1, doi. 10.1126/scisignal.aao1591

By:

Zheng, Hong;
Yu, Wen-Mei;
Waclaw, Ronald R.;
Kontaridis, Maria I.;
Neel, Benjamin G.;
Qu, Cheng-Kui

Publication type:

Article

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.

Published in:

Science Signaling, 2017, v. 10, n. 468, p. 1, doi. 10.1126/scisignal.aaf5967

By:

Simonson, Bridget;
Subramanya, Vinita;
Mun Chun Chan;
Aifeng Zhang;
Franchino, Hannabeth;
Ottaviano, Filomena;
Mishra, Manoj K.;
Knight, Ashley C.;
Hunt, Danielle;
Ghiran, Ionita;
Khurana, Tejvir S.;
Kontaridis, Maria I.;
Rosenzweig, Anthony;
Das, Saumya

Publication type:

Article

Protein tyrosine phosphatase 1B in metabolic and cardiovascular diseases: from mechanisms to therapeutics.

Published in:

Frontiers in Cardiovascular Medicine, 2024, p. 1, doi. 10.3389/fcvm.2024.1445739

By:

Yan Sun;
Dinenno, Frank A.;
Peiyang Tang;
Kontaridis, Maria I.

Publication type:

Article

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.

Published in:

Science Signaling, 2014, v. 7, n. 348, p. 1, doi. 10.1126/scisignal.2005262

By:

Lauriol, Jessica;
Keith, Kimberly;
Jaffré, Fabrice;
Couvillon, Anthony;
Saci, Abdel;
Goonasekera, Sanjeewa A.;
McCarthy, Jason R.;
Kessinger, Chase W.;
Jianxun Wang;
Qingen Ke;
Kang, Peter M.;
Molkentin, Jeffery D.;
Carpenter, Christopher;
Kontaridis, Maria I.

Publication type:

Article

SHP-2 Positively Regulates Myogenesis by Coupling to the Rho GTPase Signaling Pathway.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 12, p. 5340, doi. 10.1128/MCB.24.12.5340-5352.2004

By:

Kontaridis, Maria I.;
Eminaga, Seda;
Fornaro, Mara;
Zito, Christina Ivins;
Sordella, Raffaella;
Settleman, Jeffrey;
Bennett, Anton M.

Publication type:

Article

SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.

Published in:

Journal of Cellular Physiology, 2004, v. 199, n. 2, p. 227, doi. 10.1002/jcp.10446

By:

Christina Ivins Zito;
Maria I. Kontaridis;
Mara Fornaro;
Geng-Shen Feng;
Anton M. Bennett

Publication type:

Article

A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.

Published in:

Scientific Reports, 2016, p. 20471, doi. 10.1038/srep20471

By:

Breitkopf, Susanne B.;
Yang, Xuemei;
Begley, Michael J.;
Kulkarni, Meghana;
Chiu, Yu-Hsin;
Turke, Alexa B.;
Lauriol, Jessica;
Yuan, Min;
Qi, Jie;
Engelman, Jeffrey A.;
Hong, Pengyu;
Kontaridis, Maria I.;
Cantley, Lewis C.;
Perrimon, Norbert;
Asara, John M.

Publication type:

Article