Works by Konrad, Csaba

Results: 20

Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 10, p. N.PAG, doi. 10.15252/emmm.201808888

By:

Palomo, Gloria M;
Granatiero, Veronica;
Kawamata, Hibiki;
Konrad, Csaba;
Kim, Michelle;
Arreguin, Andrea J;
Zhao, Dazhi;
Milner, Teresa A;
Manfredi, Giovanni

Publication type:

Article

Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation.

Published in:

FASEB Journal, 2010, v. 24, n. 7, p. 2405, doi. 10.1096/fj.09-149898

By:

Chinopoulos, Christos;
Gerencser, Akos A.;
Mandi, Miklos;
Mathe, Katalin;
Töröcsik, Beata;
Doczi, Judit;
Turiak, Lilla;
Kiss, Gergely;
Konràd, Csaba;
Vajda, Szilvia;
Vereczki, Viktoria;
Oh, Richard J.;
Adam-Vizi, Vera

Publication type:

Article

Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL.

Published in:

EMBO Reports, 2023, v. 24, n. 1, p. 1, doi. 10.15252/embr.202254689

By:

Sasset, Linda;
Chowdhury, Kamrul H;
Manzo, Onorina L;
Rubinelli, Luisa;
Konrad, Csaba;
Maschek, J Alan;
Manfredi, Giovanni;
Holland, William L;
Di Lorenzo, Annarita

Publication type:

Article

Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 20, p. 3458, doi. 10.1093/hmg/ddac118

By:

Fels, Jasmine A;
Casalena, Gabriella;
Konrad, Csaba;
Holmes, Holly E;
Dellinger, Ryan W;
Manfredi, Giovanni

Publication type:

Article

Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.

Published in:

Journal of Bioenergetics & Biomembranes, 2017, v. 49, n. 1, p. 3, doi. 10.1007/s10863-016-9656-x

By:

Starkov, Anatoly;
Chinopoulos, Christos;
Starkova, Natalia;
Konrad, Csaba;
Kiss, Gergely;
Stepanova, Anna;
Popov, Vasily

Publication type:

Article

Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 16, p. 3142, doi. 10.1523/jneurosci.1804-19.2020

By:

Youyang Qu;
Konrad, Csaba;
Anderson, Corey;
Liping Qian;
Yin, Tina;
Manfredi, Giovanni;
Iadecola, Costantino;
Ping Zhou

Publication type:

Article

The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A.

Published in:

Journal of Neurochemistry, 2019, v. 148, n. 6, p. 731, doi. 10.1111/jnc.14654

By:

Stepanova, Anna;
Konrad, Csaba;
Manfredi, Giovanni;
Springett, Roger;
Ten, Vadim;
Galkin, Alexander

Publication type:

Article

Absence of Ca2+-Induced Mitochondrial Permeability Transition but Presence of Bongkrekate-Sensitive Nucleotide Exchange in C. crangon and P. serratus.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039839

By:

Konrad, Csaba;
Kiss, Gergely;
Torocsik, Beata;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

Modulation of F.

Published in:

FEBS Journal, 2011, v. 278, n. 7, p. 1112, doi. 10.1111/j.1742-4658.2011.08026.x

By:

Chinopoulos, Christos;
Konràd, Csaba;
Kiss, Gergely;
Metelkin, Eugeniy;
Töröcsik, Beata;
Zhang, Steven F.;
Starkov, Anatoly A.

Publication type:

Article

A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca.

Published in:

FEBS Journal, 2011, v. 278, n. 5, p. 822, doi. 10.1111/j.1742-4658.2010.08001.x

By:

Konràd, Csaba;
Kiss, Gergely;
Töröcsik, Beata;
Lábár, János L.;
Gerencser, Akos A.;
Mándi, Miklós;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria.

Published in:

FEBS Journal, 2009, v. 276, n. 10, p. 2713, doi. 10.1111/j.1742-4658.2009.06995.x

By:

Vajda, Szilvia;
Mándi, Miklós;
Konràd, Csaba;
Kiss, Gergely;
Ambrus, Attila;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes.

Published in:

Autophagy, 2021, v. 17, n. 12, p. 4029, doi. 10.1080/15548627.2021.1899682

By:

Granatiero, Veronica;
Sayles, Nicole M.;
Savino, Angela M.;
Konrad, Csaba;
Kharas, Michael G.;
Kawamata, Hibiki;
Manfredi, Giovanni

Publication type:

Article

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5

By:

Konrad, Csaba;
Hibiki Kawamata;
Bredvik, Kirsten G.;
Arreguin, Andrea J.;
Cajamarca, Steven A.;
Hupf, Jonathan C.;
Ravits, John M.;
Miller, Timothy M.;
Maragakis, Nicholas J.;
Hales, Chadwick M.;
Glass, Jonathan D.;
Gross, Steven;
Hiroshi Mitsumoto;
Manfredi, Giovanni

Publication type:

Article

Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0180-1

By:

Hibiki Kawamata;
Peixoto, Pablo;
Konrad, Csaba;
Palomo, Gloria;
Bredvik, Kirsten;
Gerges, Meri;
Valsecchi, Federica;
Petrucelli, Leonard;
Ravits, John M.;
Starkov, Anatoly;
Manfredi, Giovanni

Publication type:

Article

Deactivation of mitochondrial complex I after hypoxia–ischemia in the immature brain.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 9, p. 1790, doi. 10.1177/0271678X18770331

By:

Stepanova, Anna;
Konrad, Csaba;
Guerrero-Castillo, Sergio;
Manfredi, Giovanni;
Vannucci, Susan;
Arnold, Susanne;
Galkin, Alexander

Publication type:

Article

Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 12, p. 3649, doi. 10.1177/0271678X17730242

By:

Stepanova, Anna;
Kahl, Anja;
Konrad, Csaba;
Ten, Vadim;
Starkov, Anatoly S.;
Galkin, Alexander

Publication type:

Article

Better understanding the neurobiology of primary lateral sclerosis.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2020, v. 21, p. 35, doi. 10.1080/21678421.2020.1837175

By:

Ozdinler, P. Hande;
Gautam, Mukesh;
Gozutok, Oge;
Konrad, Csaba;
Manfredi, Giovanni;
Area Gomez, Estela;
Mitsumoto, Hiroshi;
Erb, Marcella L.;
Tian, Zheng;
Haase, Georg

Publication type:

Article

S1P controls endothelial sphingolipid homeostasis via ORMDL.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5883

By:

Sasset, Linda;
Chowdhury, Kamrul H.;
Manzo, Onorina L.;
Rubinelli, Luisa;
Konrad, Csaba;
Maschek, J. A.;
Manfredi, Giovanni;
Holland, William L.;
Di Lorenzo, Annarita

Publication type:

Article

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

Published in:

FASEB Journal, 2014, v. 28, n. 4, p. 1682, doi. 10.1096/fj.13-243030

By:

Kiss, Gergely;
Konrad, Csaba;
Pour-Ghaz, Issa;
Mansour, Josef J.;
Németh, Beata;
Starkov, Anatoly A.;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.

Published in:

FASEB Journal, 2013, v. 27, n. 6, p. 2392, doi. 10.1096/fj.12-220202

By:

Kiss, Gergely;
Konrad, Csaba;
Doczi, Judit;
Starkov, Anatoly A.;
Kawamata, Hibiki;
Manfredi, Giovanni;
Zhang, Steven F.;
Gibson, Gary E.;
Beal, M. Flint;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

Works by Konrad, Csaba

Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.

Forward operation of adenine nucleotide translocase during F<sub>0</sub>F<sub>1</sub>-ATPase reversal: critical role of matrix substrate-level phosphorylation.

Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL.

Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.

Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.

Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures.

The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A.

Absence of Ca<sup>2+</sup>-Induced Mitochondrial Permeability Transition but Presence of Bongkrekate-Sensitive Nucleotide Exchange in C. crangon and P. serratus.

Modulation of F.

A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca.

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca<sup>2+</sup> release from mitochondria.

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1<sup>G93A</sup> astrocytes.

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.

Deactivation of mitochondrial complex I after hypoxia–ischemia in the immature brain.

Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury.

Better understanding the neurobiology of primary lateral sclerosis.

S1P controls endothelial sphingolipid homeostasis via ORMDL.

Mitochondrial diaphorases as NAD<sup>+</sup> donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.