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Activation of apoptosis signaling eliminates CD34+ progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors.
Published in:
2012
By:
- Mak DH;
- Wang RY;
- Schober WD;
- Konopleva M;
- Cortes J;
- Kantarjian H;
- Andreeff M;
- Carter BZ;
- Mak, D H;
- Wang, R-Y;
- Schober, W D;
- Konopleva, M;
- Cortes, J;
- Kantarjian, H;
- Andreeff, M;
- Carter, B Z
Publication type:
journal article
Apoptosis effector mechanisms: A requiem performed in different keys.
Published in:
Apoptosis, 2006, v. 11, n. 6, p. 889, doi. 10.1007/s10495-006-6712-8
By:
- Hail Jr., N.;
- Carter, B. Z.;
- Konopleva, M.;
- Andreeff, M.
Publication type:
Article
Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.
Published in:
Cell Death & Differentiation, 2007, v. 14, n. 8, p. 1443, doi. 10.1038/sj.cdd.4402139
By:
- Tabe, Y.;
- Jin, L.;
- Contractor, R.;
- Gold, D.;
- Ruvolo, P.;
- Radke, S.;
- Xu, Y.;
- Tsutusmi-Ishii, Y.;
- Miyake, K.;
- Miyake, N.;
- Kondo, S.;
- Ohsaka, A.;
- Nagaoka, I.;
- Andreeff, M.;
- Konopleva, M.
Publication type:
Article
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
Published in:
2011
By:
- Jin, L.;
- Tabe, Y.;
- Kimura, S.;
- Zhou, Y.;
- Kuroda, J.;
- Asou, H.;
- Inaba, T.;
- Konopleva, M.;
- Andreeff, M.;
- Miida, T.
Publication type:
journal article
Pretreatment with Antiviral Preparation Kagocel Normalizes the Content of Bone Marrow Multipotent Stromal Cells and TNFα in Blood Serum of CBA Mice Disturbed by Administration of S. typhimurium Antigen Complex In Vivo and Maintains High Concentration of IL-10 and Th1 Cytokines
Published in:
Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 6, p. 761, doi. 10.1007/s10517-017-3898-4
By:
- Gorskaya, Yu.;
- Semenova, E.;
- Nesternko, V.;
- Suslov, A.;
- Konopleva, M.
Publication type:
Article
Effects of Kagocel on the Counts of Multipotent Stromal Cells, Expression of Cytokine Genes in Primary Cultures of Bone Marrow Stromal Cells, and Serum Cytokine Concentrations in CBA Mice.
Published in:
Bulletin of Experimental Biology & Medicine, 2015, v. 159, n. 2, p. 240, doi. 10.1007/s10517-015-2932-7
By:
- Gorskaya, Yu.;
- Grabko, V.;
- Konopleva, M.;
- Suslov, A.;
- Nesterenko, V.
Publication type:
Article
Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 7, p. 1543, doi. 10.1038/leu.2014.54
By:
- Ravandi, F;
- Arana Yi, C;
- Cortes, J E;
- Levis, M;
- Faderl, S;
- Garcia-Manero, G;
- Jabbour, E;
- Konopleva, M;
- O'Brien, S;
- Estrov, Z;
- Borthakur, G;
- Thomas, D;
- Pierce, S;
- Brandt, M;
- Pratz, K;
- Luthra, R;
- Andreeff, M;
- Kantarjian, H
Publication type:
Article
The combination of hyper-CVAD plus nelarabine as frontline therapy in adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma: MD Anderson Cancer Center experience.
Published in:
Leukemia (08876924), 2014, v. 28, n. 4, p. 973, doi. 10.1038/leu.2013.312
By:
- Jain, P;
- Kantarjian, H;
- Ravandi, F;
- Thomas, D;
- O'Brien, S;
- Kadia, T;
- Burger, J;
- Borthakur, G;
- Daver, N;
- Jabbour, E;
- Konopleva, M;
- Cortes, J;
- Pemmaraju, N;
- Kelly, M A;
- Cardenas-Turanzas, M;
- Garris, R;
- Faderl, S
Publication type:
Article
HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.
Published in:
Leukemia (08876924), 2013, v. 27, n. 6, p. 1358, doi. 10.1038/leu.2012.366
By:
- Zhou, L;
- Ruvolo, V R;
- McQueen, T;
- Chen, W;
- Samudio, I J;
- Conneely, O;
- Konopleva, M;
- Andreeff, M
Publication type:
Article
Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts.
Published in:
Leukemia (08876924), 2012, v. 26, n. 5, p. 883, doi. 10.1038/leu.2011.291
By:
- Tabe, Y;
- Jin, L;
- Iwabuchi, K;
- Wang, R-Y;
- Ichikawa, N;
- Miida, T;
- Cortes, J;
- Andreeff, M;
- Konopleva, M
Publication type:
Article
Activation of apoptosis signaling eliminates CD34<sup>+</sup> progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors.
Published in:
Leukemia (08876924), 2012, v. 26, n. 4, p. 788, doi. 10.1038/leu.2011.285
By:
- Mak, D H;
- Wang, R-Y;
- Schober, W D;
- Konopleva, M;
- Cortes, J;
- Kantarjian, H;
- Andreeff, M;
- Carter, B Z
Publication type:
Article
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
Published in:
Leukemia (08876924), 2012, v. 26, n. 4, p. 778, doi. 10.1038/leu.2011.287
By:
- Konopleva, M;
- Milella, M;
- Ruvolo, P;
- Watts, J C;
- Ricciardi, M R;
- Korchin, B;
- McQueen, T;
- Bornmann, W;
- Tsao, T;
- Bergamo, P;
- Mak, D H;
- Chen, W;
- McCubrey, J;
- Tafuri, A;
- Andreeff, M
Publication type:
Article
Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients.
Published in:
2011
By:
- Ruvolo, P P;
- Qui, Y H;
- Coombes, K R;
- Zhang, N;
- Ruvolo, V R;
- Borthakur, G;
- Konopleva, M;
- Andreeff, M;
- Kornblau, S M
Publication type:
journal article
Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1/Noxa axis.
Published in:
2010
By:
- Kojima, K.;
- Konopleva, M.;
- Tsao, T.;
- Andreeff, M.;
- Ishida, H.;
- Shiotsu, Y.;
- Jin, L.;
- Tabe, Y.;
- Nakakuma, H.
Publication type:
journal article
The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.
Published in:
2008
By:
- Kojima, K.;
- Shimanuki, M.;
- Shikami, M.;
- Samudio, I. J.;
- Ruvolo, V.;
- Corn, P.;
- Hanaoka, N.;
- Konopleva, M.;
- Andreeff, M.;
- Nakakuma, H.
Publication type:
journal article
Synthetic triterpenoids have cytotoxicity in pediatric acute lymphoblastic leukemia cell lines but cytotoxicity is independent of induced ceramide increase in MOLT-4 cells.
Published in:
2008
By:
- Kong, G.;
- Wang, D.;
- Wang, H.;
- Wu, J.;
- Bielawski, J.;
- Konopleva, M.;
- Andreeff, M.;
- Ruvolo, P. P.;
- Maurer, B. J.
Publication type:
Letter
Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
Published in:
2008
By:
- Zhang, W.;
- Konopleva, M.;
- Ruvolo, V. R.;
- McQueen, T.;
- Evans, R. L.;
- Bornmann, W. G.;
- McCubrey, J.;
- Cortes, J.;
- Andreeff, M.
Publication type:
journal article
Bcl2 phosphorylation and active PKC α are associated with poor survival in AML.
Published in:
2006
By:
- Kurinna, S;
- Konopleva, M;
- Palla, S L;
- Chen, W;
- Kornblau, S;
- Contractor, R;
- Deng, X;
- May, W S;
- Andreeff, M;
- Ruvolo, P P
Publication type:
Letter
Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Published in:
Leukemia (08876924), 2005, v. 19, n. 11, p. 1977, doi. 10.1038/sj.leu.2403929
By:
- Zhang, W.;
- McQueen, T.;
- Schober, W.;
- Rassidakis, G.;
- Andreeff, M.;
- Konopleva, M.
Publication type:
Article
Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia.
Published in:
Leukemia (08876924), 2005, v. 19, n. 9, p. 1543, doi. 10.1038/sj.leu.2403859
By:
- Ricciardi, M. R.;
- McQueen, T.;
- Chism, D.;
- Milella, M.;
- Estey, E.;
- Kaldjian, E.;
- Sebolt-Leopold, J.;
- Konopleva, M.;
- Andreeff, M.
Publication type:
Article
The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells.
Published in:
2005
By:
- Konopleva, M.;
- Contractor, R.;
- Kurinna, S. M.;
- Chen, W.;
- Andreeff, M.;
- Ruvolo, P. P.
Publication type:
journal article
PKC a mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation.
Published in:
Leukemia (08876924), 2004, v. 18, n. 3, p. 505, doi. 10.1038/sj.leu.2403275
By:
- Jiffar, T.;
- Kurinna, S.;
- Suck, G.;
- Carlson-Bremer, D.;
- Ricciardi, M.R.;
- Konopleva, M.;
- Andreeff, M.;
- Ruvolo, P.P.
Publication type:
Article
Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.
Published in:
2004
By:
- Zhao, S.;
- Konopleva, M.;
- Cabreira-Hansen, M.;
- Xie, Z.;
- Hu, W.;
- Milella, M.;
- Estrov, Z.;
- Mills, G.B.;
- Andreeff, M.
Publication type:
journal article
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptosic proteins.
Published in:
Leukemia (08876924), 2002, v. 16, n. 9, p. 1713, doi. 10.1038/sj.leu.2402608
By:
- Konopleva, M.;
- Konoplev, S.;
- Hu, W.;
- Zaritskey, A.Y.;
- Afanasiev, B.V.;
- Andreeff, M.
Publication type:
Article
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid.
Published in:
1999
By:
- Andreeff, M;
- Jiang, S;
- Zhang, X;
- Konopleva, M;
- Estrov, Z;
- Snell, V E;
- Xie, Z;
- Okcu, M F;
- Sanchez-Williams, G;
- Dong, J;
- Estey, E H;
- Champlin, R C;
- Kornblau, S M;
- Reed, J C;
- Zhao, S
Publication type:
journal article
Leukemia cell mobilization with G-CSF plus plerixafor during busulfan-fludarabine conditioning for allogeneic stem cell transplantation.
Published in:
Bone Marrow Transplantation, 2015, v. 50, n. 7, p. 939, doi. 10.1038/bmt.2015.58
By:
- Konopleva, M;
- Benton, C B;
- Thall, P F;
- Zeng, Z;
- Shpall, E;
- Ciurea, S;
- Kebriaei, P;
- Alousi, A;
- Popat, U;
- Anderlini, P;
- Nieto, Y;
- Parmar, S;
- Qiao, W;
- Chen, J;
- Rondon, G;
- McMullin, B;
- Wang, R-Y;
- Lu, H;
- Schober, W;
- Woodworth, G
Publication type:
Article
FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells.
Published in:
Bone Marrow Transplantation, 2014, v. 49, n. 6, p. 793, doi. 10.1038/bmt.2014.57
By:
- Liu, X;
- Robinson, S N;
- Setoyama, T;
- Tung, S S;
- D'Abundo, L;
- Shah, M Y;
- Yang, H;
- Yvon, E;
- Shah, N;
- Konopleva, M;
- Garcia-Manero, G;
- McNiece, I;
- Rezvani, K;
- Calin, G A;
- Shpall, E J;
- Parmar, S
Publication type:
Article
Photoreactivation of UV-exposed Escherichia coli K12 AB1886 uvrA6 via luminescence of Photobacterium leiognathi luciferase.
Published in:
Molecular Biology, 2015, v. 49, n. 6, p. 928, doi. 10.1134/S0026893315060175
By:
- Melkina, O.;
- Kotova, V.;
- Konopleva, M.;
- Manukhov, I.;
- Pustovoit, K.;
- Zavilgelsky, G.
Publication type:
Article

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