Works by Kokubo, Toshiaki

Results: 22

Quantifying initial cellular events of mouse radiation lymphomagenesis and its tumor prevention in vivo by positron emission tomography and magnetic resonance imaging.

Published in:

Molecular Oncology, 2015, v. 9, n. 3, p. 740, doi. 10.1016/j.molonc.2014.11.009

By:

Hasegawa, Sumitaka;
Morokoshi, Yukie;
Tsuji, Atsushi B.;
Kokubo, Toshiaki;
Aoki, Ichio;
Furukawa, Takako;
Zhang, Ming-Rong;
Saga, Tsuneo

Publication type:

Article

Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice.

Published in:

Carcinogenesis, 2010, v. 31, n. 9, p. 1694, doi. 10.1093/carcin/bgq145

By:

Ishida, Yuka;
Takabatake, Takashi;
Kakinuma, Shizuko;
Doi, Kazutaka;
Yamauchi, Kazumi;
Kaminishi, Mutsumi;
Kito, Seiji;
Ohta, Yuki;
Amasaki, Yoshiko;
Moritake, Hiroyuki;
Kokubo, Toshiaki;
Nishimura, Mayumi;
Nishikawa, Tetsu;
Hino, Okio;
Shimada, Yoshiya

Publication type:

Article

Biological measures to minimize the risk of radiotherapy-associated second cancer: A research perspective.

Published in:

International Journal of Radiation Biology, 2016, v. 92, n. 6, p. 289, doi. 10.3109/09553002.2016.1152413

By:

Imaoka, Tatsuhiko;
Ishii, Nobuyoshi;
Kawaguchi, Isao;
Homma-Takeda, Shino;
Doi, Kazutaka;
Daino, Kazuhiro;
Nakanishi, Ikuo;
Tagami, Keiko;
Kokubo, Toshiaki;
Morioka, Takamitsu;
Hosoki, Ayaka;
Takabatake, Masaru;
Yoshinaga, Shinji

Publication type:

Article

Uranium dynamics and developmental sensitivity in rat kidney.

Published in:

Journal of Applied Toxicology, 2013, v. 33, n. 7, p. 685, doi. 10.1002/jat.2870

By:

Homma‐Takeda, Shino;
Kokubo, Toshiaki;
Terada, Yasuko;
Suzuki, Kyoko;
Ueno, Shunji;
Hayao, Tatsuo;
Inoue, Tatsuya;
Kitahara, Keisuke;
Blyth, Benjamin J.;
Nishimura, Mayumi;
Shimada, Yoshiya

Publication type:

Article

Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer's disease mouse model.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-91689-3

By:

Lee, Won-Seok;
Kokubo, Toshiaki;
Choi, Younshick;
Hamano, Tsuyoshi;
Zaboronok, Alexander;
Ishikawa, Takaaki;
Kwon, Oh-Dae;
Kim, EunHo;
Kim, Jong-Ki

Publication type:

Article

Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer's disease mouse model.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-91689-3

By:

Lee, Won-Seok;
Kokubo, Toshiaki;
Choi, Younshick;
Hamano, Tsuyoshi;
Zaboronok, Alexander;
Ishikawa, Takaaki;
Kwon, Oh-Dae;
Kim, EunHo;
Kim, Jong-Ki

Publication type:

Article

Fluorescence-based visualization of autophagic activity predicts mouse embryo viability.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04533

By:

Satoshi Tsukamoto;
Taichi Hara;
Atsushi Yamamoto;
Seiji Kito;
Naojiro Minami;
Toshiro Kubota;
Ken Sato;
Toshiaki Kokubo

Publication type:

Article

Brca1L63X/+ rat is a novel model of human BRCA1 deficiency displaying susceptibility to radiation‐induced mammary cancer.

Published in:

Cancer Science, 2022, v. 113, n. 10, p. 3362, doi. 10.1111/cas.15485

By:

Nakamura, Yuzuki;
Kubota, Jo;
Nishimura, Yukiko;
Nagata, Kento;
Nishimura, Mayumi;
Daino, Kazuhiro;
Ishikawa, Atsuko;
Kaneko, Takehito;
Mashimo, Tomoji;
Kokubo, Toshiaki;
Takabatake, Masaru;
Inoue, Kazumasa;
Fukushi, Masahiro;
Arai, Masami;
Saito, Mitsue;
Shimada, Yoshiya;
Kakinuma, Shizuko;
Imaoka, Tatsuhiko

Publication type:

Article

Interstitial chromosomal deletion of the tuberous sclerosis complex 2 locus is a signature for radiation‐associated renal tumors in Eker rats.

Published in:

Cancer Science, 2020, v. 111, n. 3, p. 840, doi. 10.1111/cas.14307

By:

Inoue, Tatsuya;
Kokubo, Toshiaki;
Daino, Kazuhiro;
Yanagihara, Hiromi;
Watanabe, Fumiko;
Tsuruoka, Chizuru;
Amasaki, Yoshiko;
Morioka, Takamitsu;
Homma‐Takeda, Shino;
Kobayashi, Toshiyuki;
Hino, Okio;
Shimada, Yoshiya;
Kakinuma, Shizuko

Publication type:

Article

Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice.

Published in:

Cancer Science, 2015, v. 106, n. 3, p. 217, doi. 10.1111/cas.12591

By:

Morioka, Takamitsu;
Miyoshi ‐ Imamura, Tomoko;
Blyth, Benjamin J.;
Kaminishi, Mutsumi;
Kokubo, Toshiaki;
Nishimura, Mayumi;
Kito, Seiji;
Tokairin, Yutaka;
Tani, Shusuke;
Murakami ‐ Murofushi, Kimiko;
Yoshimi, Naoki;
Shimada, Yoshiya;
Kakinuma, Shizuko

Publication type:

Article

Age dependence of radiation-induced renal cell carcinomas in an Eker rat model.

Published in:

Cancer Science, 2010, v. 101, n. 3, p. 616, doi. 10.1111/j.1349-7006.2009.01456.x

By:

Kokubo, Toshiaki;
Kakinuma, Shizuko;
Kobayashi, Toshiyuki;
Watanabe, Fumiko;
Iritani, Riichirou;
Tateno, Kaori;
Nishimura, Mayumi;
Nishikawa, Tetsu;
Hino, Okio;
Shimada, Yoshiya

Publication type:

Article

Prominent Dose-Rate Effect and Its Age Dependence of Rat Mammary Carcinogenesis Induced by Continuous Gamma-Ray Exposure.

Published in:

Radiation Research, 2019, v. 191, n. 3, p. 245, doi. 10.1667/RR15094.1

By:

Imaoka, Tatsuhiko;
Nishimura, Mayumi;
Daino, Kazuhiro;
Hosoki, Ayaka;
Takabatake, Masaru;
Nishimura, Yukiko;
Kokubo, Toshiaki;
Morioka, Takamitsu;
Doi, Kazutaka;
Shimada, Yoshiya;
Kakinuma, Shizuko

Publication type:

Article

Age Modifies the Effect of 2-MeV Fast Neutrons on Rat Mammary Carcinogenesis.

Published in:

Radiation Research, 2017, v. 188, n. 4, p. 419, doi. 10.1667/RR14829.1

By:

Imaoka, Tatsuhiko;
Nishimura, Mayumi;
Daino, Kazuhiro;
Hosoki, Ayaka;
Takabatake, Masaru;
Kokubo, Toshiaki;
Doi, Kazutaka;
Showler, Kaye;
Nishimura, Yukiko;
Moriyama, Hitomi;
Morioka, Takamitsu;
Shimada, Yoshiya;
Kakinuma, Shizuko

Publication type:

Article

Morphological analysis on comparison of organic and chemical fertilizers on grain quality of rice at different planting densities.

Published in:

Plant Production Science, 2019, v. 22, n. 4, p. 510, doi. 10.1080/1343943X.2019.1657777

By:

Kakar, Kifayatullah;
Nitta, Youji;
Asagi, Naomi;
Komatsuzaki, Masakazu;
Shiotsu, Fumitaka;
Kokubo, Toshiaki;
Xuan, Tran Dang

Publication type:

Article

Filobacterium spp.: what we know and what we should clarify.

Published in:

Experimental Animals, 2022, v. 71, p. 90

By:

Fumio Ike;
Ayako Kajita;
Toshiaki Kokubo

Publication type:

Article

Novel method for evaluating the health condition of mice in space through a video downlink.

Published in:

Experimental Animals, 2021, v. 70, n. 2, p. 236, doi. 10.1538/expanim.20-0102

By:

Akane YUMOTO;
Toshiaki KOKUBO;
Ryutaro IZUMI;
Michihiko SHIMOMURA;
Osamu FUNATSU;
Motoki N. TADA;
Naoko OTA-MURAKAMI;
Kayoko IINO;
Masaki SHIRAKAWA;
Hiroyasu MIZUNO;
Takashi KUDO;
Satoru TAKAHASHI;
Takafumi SUZUKI;
Akira URUNO;
Masayuki YAMAMOTO;
Dai SHIBA

Publication type:

Article

Transcriptome Analysis by RNA Sequencing of Mouse Embryonic Stem Cells Stocked on International Space Station for 1584 Days in Frozen State after Culture on the Ground.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3283, doi. 10.3390/ijms25063283

By:

Yoshida, Kayo;
Hada, Megumi;
Hayashi, Masami;
Kizu, Akane;
Kitada, Kohei;
Eguchi-Kasai, Kiyomi;
Kokubo, Toshiaki;
Teramura, Takeshi;
Hashizume Suzuki, Hiromi;
Watanabe, Hitomi;
Kondoh, Gen;
Nagamatsu, Aiko;
Saganti, Premkumar;
Muratani, Masafumi;
Cucinotta, Francis A.;
Morita, Takashi

Publication type:

Article

Phosphorus Localization and Its Involvement in the Formation of Concentrated Uranium in the Renal Proximal Tubules of Rats Exposed to Uranyl Acetate.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4677, doi. 10.3390/ijms20194677

By:

Homma-Takeda, Shino;
Numako, Chiya;
Kitahara, Keisuke;
Yoshida, Takanori;
Oikawa, Masakazu;
Terada, Yasuko;
Kokubo, Toshiaki;
Shimada, Yoshiya

Publication type:

Article

DOSE-RATE EFFECT OF RADIATION ON RAT MAMMARY CARCINOGENESIS AND AN EMERGING ROLE FOR STEM CELL BIOLOGY.

Published in:

Radiation Protection Dosimetry, 2022, v. 198, n. 13-15, p. 1036, doi. 10.1093/rpd/ncac050

By:

Imaoka, Tatsuhiko;
Nishimura, Mayumi;
Daino, Kazuhiro;
Hosoki, Ayaka;
Kudo, Ken-ichi;
Iizuka, Daisuke;
Nagata, Kento;
Takabatake, Masaru;
Nishimura, Yukiko;
Kokubo, Toshiaki;
Morioka, Takamitsu;
Doi, Kazutaka;
Shimada, Yoshiya;
Kakinuma, Shizuko

Publication type:

Article

Differential effect of parity on rat mammary carcinogenesis after pre- or post-pubertal exposure to radiation.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32406-1

By:

Takabatake, Masaru;
Daino, Kazuhiro;
Imaoka, Tatsuhiko;
Blyth, Benjamin J.;
Kokubo, Toshiaki;
Nishimura, Yukiko;
Showler, Kaye;
Hosoki, Ayaka;
Moriyama, Hitomi;
Nishimura, Mayumi;
Kakinuma, Shizuko;
Fukushi, Masahiro;
Shimada, Yoshiya

Publication type:

Article

Development of mammary cancer in γ-irradiated F1 hybrids of susceptible Sprague-Dawley and resistant Copenhagen rats, with copy-number losses that pinpoint potential tumor suppressors.

Published in:

PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0255968

By:

Nishimura, Mayumi;
Daino, Kazuhiro;
Fukuda, Maki;
Tanaka, Ikuya;
Moriyama, Hitomi;
Showler, Kaye;
Nishimura, Yukiko;
Takabatake, Masaru;
Kokubo, Toshiaki;
Ishikawa, Atsuko;
Inoue, Kazumasa;
Fukushi, Masahiro;
Kakinuma, Shizuko;
Imaoka, Tatsuhiko;
Shimada, Yoshiya

Publication type:

Article

Cancer prevention by adult-onset calorie restriction after infant exposure to ionizing radiation in B6C3F1 male mice.

Published in:

International Journal of Cancer, 2014, v. 135, n. 5, p. 1038, doi. 10.1002/ijc.28751

By:

Shang, Yi;
Kakinuma, Shizuko;
Yamauchi, Kazumi;
Morioka, Takamitsu;
Kokubo, Toshiaki;
Tani, Shusuke;
Takabatake, Takashi;
Kataoka, Yasushi;
Shimada, Yoshiya

Publication type:

Article

Works by Kokubo, Toshiaki

Quantifying initial cellular events of mouse radiation lymphomagenesis and its tumor prevention in vivo by positron emission tomography and magnetic resonance imaging.

Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice.

Biological measures to minimize the risk of radiotherapy-associated second cancer: A research perspective.

Uranium dynamics and developmental sensitivity in rat kidney.

Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer's disease mouse model.

Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer's disease mouse model.

Fluorescence-based visualization of autophagic activity predicts mouse embryo viability.

Brca1<sup>L63X</sup><sup>/+</sup> rat is a novel model of human BRCA1 deficiency displaying susceptibility to radiation‐induced mammary cancer.

Interstitial chromosomal deletion of the tuberous sclerosis complex 2 locus is a signature for radiation‐associated renal tumors in Eker rats.

Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice.

Age dependence of radiation-induced renal cell carcinomas in an Eker rat model.

Prominent Dose-Rate Effect and Its Age Dependence of Rat Mammary Carcinogenesis Induced by Continuous Gamma-Ray Exposure.

Age Modifies the Effect of 2-MeV Fast Neutrons on Rat Mammary Carcinogenesis.

Morphological analysis on comparison of organic and chemical fertilizers on grain quality of rice at different planting densities.

Filobacterium spp.: what we know and what we should clarify.

Novel method for evaluating the health condition of mice in space through a video downlink.

Transcriptome Analysis by RNA Sequencing of Mouse Embryonic Stem Cells Stocked on International Space Station for 1584 Days in Frozen State after Culture on the Ground.

Phosphorus Localization and Its Involvement in the Formation of Concentrated Uranium in the Renal Proximal Tubules of Rats Exposed to Uranyl Acetate.

DOSE-RATE EFFECT OF RADIATION ON RAT MAMMARY CARCINOGENESIS AND AN EMERGING ROLE FOR STEM CELL BIOLOGY.

Differential effect of parity on rat mammary carcinogenesis after pre- or post-pubertal exposure to radiation.

Development of mammary cancer in γ-irradiated F<sub>1</sub> hybrids of susceptible Sprague-Dawley and resistant Copenhagen rats, with copy-number losses that pinpoint potential tumor suppressors.

Cancer prevention by adult-onset calorie restriction after infant exposure to ionizing radiation in B6C3F1 male mice.