Works by Kokaia, Merab

Results: 44

Tuning afferent synapses of hippocampal interneurons by neuropeptide Y.

Published in:

Hippocampus, 2011, v. 21, n. 2, p. 198, doi. 10.1002/hipo.20740

By:

Ledri, Marco;
Sørensen, Andreas Toft;
Erdelyi, Ferenc;
Szabo, Gabor;
Kokaia, Merab

Publication type:

Article

NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning.

Published in:

Hippocampus, 2008, v. 18, n. 6, p. 564, doi. 10.1002/hipo.20415

By:

Sørensen, Andreas T.;
Kanter-Schlifke, Irene;
Carli, Mirjana;
Balducci, Claudia;
Noe, Francesco;
During, Matthew J.;
Vezzani, Annamaria;
Kokaia, Merab

Publication type:

Article

Long-term potentiation of single subicular neurons in mice.

Published in:

Hippocampus, 2000, v. 10, n. 6, p. 684, doi. 10.1002/1098-1063(2000)10:6<684::AID-HIPO1006>3.0.CO;2-H

By:

Kokaia, Merab

Publication type:

Article

Chronic BDNF deficiency permanently modifies excitatory synapses in the piriform cortex.

Published in:

Journal of Neuroscience Research, 2005, v. 81, n. 5, p. 696

By:

Avtandil Nanobashvili;
Katherine Jakubs;
Merab Kokaia

Publication type:

Article

Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01270-x

By:

Gonzalez-Ramos, Ana;
Waloschková, Eliška;
Mikroulis, Apostolos;
Kokaia, Zaal;
Bengzon, Johan;
Ledri, Marco;
Andersson, My;
Kokaia, Merab

Publication type:

Article

VEGF Receptor-2 (Flk-1) Overexpression in Mice Counteracts Focal Epileptic Seizures.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040535

By:

Nikitidou, Litsa;
Kanter-Schlifke, Irene;
Dhondt, Joke;
Carmeliet, Peter;
Lambrechts, Diether;
Kokaia, Mérab

Publication type:

Article

Functional Integration of Grafted Neural Stem Cell-Derived Dopaminergic Neurons Monitored by Optogenetics in an In Vitro Parkinson Model.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017560

By:

Tønnesen, Jan;
Parish, Clare L.;
Sørensen, Andreas T.;
Andersson, Angelica;
Lundberg, Cecilia;
Deisseroth, Karl;
Arenas, Ernest;
Lindvall, Olle;
Kokaia, Merab

Publication type:

Article

Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor.

Published in:

FASEB Journal, 2022, v. 36, n. 3, p. 1, doi. 10.1096/fj.202101815R

By:

Mikroulis, Apostolos;
Ledri, Marco;
Ruffolo, Gabriele;
Palma, Eleonora;
Sperk, Günther;
Dalli, Jesmond;
Vezzani, Annamaria;
Kokaia, Merab

Publication type:

Article

Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/4518160

By:

Tsverava, Lia;
Kandashvili, Manana;
Margvelani, Giorgi;
Lortkipanidze, Tamar;
Gamkrelidze, Georgi;
Lepsveridze, Eka;
Kokaia, Merab;
Solomonia, Revaz

Publication type:

Article

Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 9, p. 2778, doi. 10.1093/brain/awq219

By:

Woldbye, David P. D.;
Ängehagen, Mikael;
Gøtzsche, Casper R.;
Elbrønd-Bek, Heidi;
Sørensen, Andreas T.;
Christiansen, Søren H.;
Olesen, Mikkel V.;
Nikitidou, Litsa;
Hansen, Thomas v. O.;
Kanter-Schlifke, Irene;
Kokaia, Merab

Publication type:

Article

Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 26, p. 9622, doi. 10.1523/JNEUROSCI.3973-14.2015

By:

Ledri, Marco;
Sørensen, Andreas T.;
Madsen, Marita G.;
Christiansen, Søren H.;
Ledri, Litsa Nikitidou;
Cifra, Alessandra;
Bengzon, Johan;
Lindberg, Eva;
Pinborg, Lars H.;
Jespersen, Bo;
Gøtzsche, Casper R.;
Woldbye, David P. D.;
Andersson, My;
Kokaia, Merab

Publication type:

Article

Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 9, p. 3364, doi. 10.1523/JNEUROSCI.2734-13.2014

By:

Ledri, Marco;
Madsen, Marita Grønning;
Nikitidou, Litsa;
Kirik, Deniz;
Kokaia, Merab

Publication type:

Article

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice.

Published in:

2008

By:

Parish, Clare L.;
Castelo-Branco, Gonçalo;
Rawal, Nina;
Tonnesen, Jan;
Sorensen, Andreas Toft;
Salto, Carmen;
Kokaia, Merab;
Lindvall, Olle;
Arenas, Ernest;
Castelo-Branco, Gonçalo

Publication type:

journal article

Optogenetic control of human neurons in organotypic brain cultures.

Published in:

Scientific Reports, 2016, p. 24818, doi. 10.1038/srep24818

By:

Andersson, My;
Avaliani, Natalia;
Svensson, Andreas;
Wickham, Jenny;
Pinborg, Lars H.;
Jespersen, Bo;
Christiansen, Søren H.;
Bengzon, Johan;
Woldbye, David P.D.;
Kokaia, Merab

Publication type:

Article

Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus.

Published in:

European Journal of Neuroscience, 2000, v. 12, n. 2, p. 662, doi. 10.1046/j.1460-9568.2000.00956.x

By:

Asztely, Fredrik;
Kokaia, Merab;
Olofsdotter, Klara;
Örtegren, Unn;
Lindvall, Olle

Publication type:

Article

Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters.

Published in:

European Journal of Neuroscience, 1994, v. 6, n. 4, p. 587, doi. 10.1111/j.1460-9568.1994.tb00303.x

By:

Kokaia, Zaal;
Metsis, Madis;
Kokaia, Merab;
Bengzon, Johan;
Elmér, Eskil;
Smith, Maj-Lis;
Timmusk, Tõnis;
Siesjö, Bo K.;
Persson, Håkan;
Lindvall, Olle

Publication type:

Article

Regional Forebrain Noradrenalin Release in Response to Focal and Generalized Seizures Induced by Hippocampal Kindling Stimulation.

Published in:

European Journal of Neuroscience, 1992, v. 4, n. 3, p. 278, doi. 10.1111/j.1460-9568.1992.tb00875.x

By:

Bengzon, Johan;
Kikvadze, Irakli;
Kokaia, Merab;
Lindvall, Olle

Publication type:

Article

Preventing epileptogenesis by interaction between inositol isomers and proteins.

Published in:

Epilepsia Open, 2025, v. 10, n. 1, p. 120, doi. 10.1002/epi4.13061

By:

Tsverava, Lia;
Kharkhelauri, Luka;
Lagani, Vincenzo;
Gamkrelidze, Giorgi;
Bokuchava, Veriko;
Kiguradze, Tamar;
Kokaia, Merab;
Solomonia, Revaz

Publication type:

Article

Seizure Suppression by GDNF Gene Therapy in Animal Models of Epilepsy.

Published in:

Molecular Therapy, 2007, v. 15, n. 6, p. 1106, doi. 10.1038/sj.mt.6300148

By:

Kanter-Schlifke, Irene;
Georgievska, Biljana;
Kirik, Deniz;
Kokaia, Merab

Publication type:

Article

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons.

Published in:

Advanced Science, 2019, v. 6, n. 24, p. N.PAG, doi. 10.1002/advs.201902011

By:

Vasudevan, Shashank;
Kajtez, Janko;
Bunea, Ada‐Ioana;
Gonzalez‐Ramos, Ana;
Ramos‐Moreno, Tania;
Heiskanen, Arto;
Kokaia, Merab;
Larsen, Niels B.;
Martínez‐Serrano, Alberto;
Keller, Stephan S.;
Emnéus, Jenny

Publication type:

Article

Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.

Published in:

European Journal of Neuroscience, 2012, v. 36, n. 1, p. 1971, doi. 10.1111/j.1460-9568.2012.08080.x

By:

Ledri, Marco;
Nikitidou, Litsa;
Erdelyi, Ferenc;
Szabo, Gabor;
Kirik, Deniz;
Deisseroth, Karl;
Kokaia, Merab

Publication type:

Article

Seizure-induced neurogenesis in the adult brain.

Published in:

European Journal of Neuroscience, 2011, v. 33, n. 6, p. 1133, doi. 10.1111/j.1460-9568.2011.07612.x

By:

Kokaia, Merab

Publication type:

Article

Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.

Published in:

European Journal of Neuroscience, 2005, v. 21, n. 10, p. 2793, doi. 10.1111/j.1460-9568.2005.04116.x

By:

Sørensen, Andreas Toft;
Thompson, Lachlan;
Kirik, Deniz;
Björklund, Anders;
Lindvall, Olle;
Kokaia, Merab

Publication type:

Article

Preserved Function of Afferent Parvalbumin-Positive Perisomatic Inhibitory Synapses of Dentate Granule Cells in Rapidly Kindled Mice.

Published in:

Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2017.00433

By:

Hansen, Marita G.;
Ledri, Litsa N.;
Kirik, Deniz;
Kokaia, Merab;
Ledri, Marco

Publication type:

Article

Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56062-1

By:

Wickham, Jenny;
Ledri, Marco;
Bengzon, Johan;
Jespersen, Bo;
Pinborg, Lars H.;
Englund, Elisabet;
Woldbye, David P. D.;
Andersson, My;
Kokaia, Merab

Publication type:

Article

Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 11, p. 2144, doi. 10.1523/JNEUROSCI.0435-18.2018

By:

Paolone, Giovanna;
Falcicchia, Chiara;
Lovisari, Francesca;
Kokaia, Merab;
Bell, William J.;
Fradet, Tracie;
Barbieri, Mario;
Wahlberg, Lars U.;
Emerich, Dwaine F.;
Simonato, Michele

Publication type:

Article

GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13190, doi. 10.3390/ijms232113190

By:

Mikroulis, Apostolos;
Waloschková, Eliška;
Bengzon, Johan;
Woldbye, David;
Pinborg, Lars H.;
Jespersen, Bo;
Avila, Anna Sanchez;
Laszlo, Zsofia I.;
Henstridge, Christopher;
Ledri, Marco;
Kokaia, Merab

Publication type:

Article

Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1198, doi. 10.3390/ijms23031198

By:

Kandashvili, Manana;
Gamkrelidze, Georgi;
Tsverava, Lia;
Lordkipanidze, Tamar;
Lepsveridze, Eka;
Lagani, Vincenzo;
Burjanadze, Maia;
Dashniani, Manana;
Kokaia, Merab;
Solomonia, Revaz

Publication type:

Article

Human Stem Cell-Derived GABAergic Interneurons Establish Efferent Synapses onto Host Neurons in Rat Epileptic Hippocampus and Inhibit Spontaneous Recurrent Seizures.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13243, doi. 10.3390/ijms222413243

By:

Waloschková, Eliška;
Gonzalez-Ramos, Ana;
Mikroulis, Apostolos;
Kudláček, Jan;
Andersson, My;
Ledri, Marco;
Kokaia, Merab

Publication type:

Article

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus.

Published in:

Stem Cells International, 2017, p. 1, doi. 10.1155/2017/5718608

By:

Avaliani, Natalia;
Pfisterer, Ulrich;
Heuer, Andreas;
Parmar, Malin;
Kokaia, Merab;
Andersson, My

Publication type:

Article

Optogenetics Reveal Delayed Afferent Synaptogenesis on Grafted Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors.

Published in:

Stem Cells, 2014, v. 32, n. 12, p. 3088, doi. 10.1002/stem.1823

By:

Avaliani, Natalia;
Sørensen, Andreas Toft;
Ledri, Marco;
Bengzon, Johan;
Koch, Philipp;
Brüstle, Oliver;
Deisseroth, Karl;
Andersson, My;
Kokaia, Merab

Publication type:

Article

Epilepsy and optogenetics: can seizures be controlled by light?

Published in:

Clinical Science, 2017, v. 131, n. 14, p. 1605, doi. 10.1042/CS20160492

By:

Tønnesen, Jan;
Kokaia, Merab

Publication type:

Article

Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 7, p. 1281, doi. 10.1111/epi.16091

By:

Pitkänen, Asla;
Henshall, David C.;
Cross, J. Helen;
Guerrini, Renzo;
Jozwiak, Sergiusz;
Kokaia, Merab;
Simonato, Michele;
Sisodiya, Sanjay;
Mifsud, Janet

Publication type:

Article

WONOEP appraisal: Optogenetic tools to suppress seizures and explore the mechanisms of epileptogenesis.

Published in:

Epilepsia (Series 4), 2014, v. 55, n. 11, p. 1693, doi. 10.1111/epi.12804

By:

Ritter, Laura Mantoan;
Golshani, Peyman;
Takahashi, Koji;
Dufour, Suzie;
Valiante, Taufik;
Kokaia, Merab

Publication type:

Article

Encapsulated galanin-producing cells attenuate focal epileptic seizures in the hippocampus.

Published in:

Epilepsia (Series 4), 2014, v. 55, n. 1, p. 167, doi. 10.1111/epi.12470

By:

Nikitidou, Litsa;
Torp, Malene;
Fjord‐Larsen, Lone;
Kusk, Philip;
Wahlberg, Lars U.;
Kokaia, Mérab

Publication type:

Article

Epilepsy therapy development: Technical and methodologic issues in studies with animal models.

Published in:

Epilepsia (Series 4), 2013, v. 54, p. 13, doi. 10.1111/epi.12295

By:

Galanopoulou, Aristea S.;
Kokaia, Merab;
Loeb, Jeffrey A.;
Nehlig, Astrid;
Pitkänen, Asla;
Rogawski, Michael A.;
Staley, Kevin J.;
Whittemore, Vicky H.;
Edward Dudek, F.

Publication type:

Article

Proposal for a 'phase II' multicenter trial model for preclinical new antiepilepsy therapy development.

Published in:

Epilepsia (Series 4), 2013, v. 54, p. 70, doi. 10.1111/epi.12300

By:

O'Brien, Terence J.;
Ben‐Menachem, Elinor;
Bertram, Edward H.;
Collins, Stephen D.;
Kokaia, Merab;
Lerche, Holger;
Klitgaard, Henrik;
Staley, Kevin J.;
Vaudano, Elisabetta;
Walker, Matthew C.;
Simonato, Michele

Publication type:

Article

Novel approaches to epilepsy treatment.

Published in:

Epilepsia (Series 4), 2013, v. 54, n. 1, p. 1, doi. 10.1111/epi.12000

By:

Sørensen, Andreas T.;
Kokaia, Merab

Publication type:

Article

Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies.

Published in:

Frontiers in Molecular Neuroscience, 2021, v. 14, p. 1, doi. 10.3389/fnmol.2021.778134

By:

Ledri, Marco;
Sørensen, Andreas T.;
Kokaia, Merab;
Woldbye, David P. D.;
Gøtzsche, Casper R.

Publication type:

Article

Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats.

Published in:

Frontiers in Molecular Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnmol.2020.603409

By:

Szczygieł, Julia Alicja;
Danielsen, Kira Iben;
Melin, Esbjörn;
Rosenkranz, Søren Hofman;
Pankratova, Stanislava;
Ericsson, Annika;
Agerman, Karin;
Kokaia, Merab;
Woldbye, David Paul Drucker

Publication type:

Article

Neural Stem and Progenitor Cells Retain Their Potential for Proliferation and Differentiation into Functional Neurons Despite Lower Number in Aged Brain.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 14, p. 4408, doi. 10.1523/JNEUROSCI.6003-08.2009

By:

Ahlenius, Henrik;
Visan, Violeta;
Kokaia, Merab;
Lindvall, Olle;
Kokaia, Zaal

Publication type:

Article

Inflammation Regulates Functional Integration of Neurons Born in Adult Brain.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 47, p. 12477, doi. 10.1523/JNEUROSCI.3240-08.2008

By:

Jakubs, Katherine;
Bonde, Sara;
Iosif, Robert E.;
Ekdahl, Christine T.;
Kokaia, Zaal;
Kokaia, Merab;
Lindvall1, Olle

Publication type:

Article

Light-activated channels in acute seizures.

Published in:

Epilepsia (Series 4), 2011, v. 52, p. 16, doi. 10.1111/j.1528-1167.2011.03226.x

By:

Kokaia, Merab

Publication type:

Article

Gene therapy of focal-onset epilepsy by adeno-associated virus vector-mediated overexpression of neuropeptide Y.

Published in:

Epilepsia (Series 4), 2010, v. 51, p. 96, doi. 10.1111/j.1528-1167.2010.02882.x

By:

Noe', Francesco M.;
Sørensen, Andreas T.;
Kokaia, Merab;
Vezzani, Annamaria

Publication type:

Article