Works matching AU Kojetin, Douglas J.

Results: 22

Molecular basis of ligand-dependent Nurr1-RXRα activation.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85039

By:

Xiaoyu Yu;
Jinsai Shang;
Kojetin, Douglas J.

Publication type:

Article

REV-ERB and ROR nuclear receptors as drug targets.

Published in:

Nature Reviews Drug Discovery, 2014, v. 13, n. 3, p. 197, doi. 10.1038/nrd4100

By:

Kojetin, Douglas J.;
Burris, Thomas P.

Publication type:

Article

Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.99782

By:

Jinsai Shang;
Kojetin, Douglas J.

Publication type:

Article

Corrigendum to: Sub-classification of response regulators using the surface characteristics of their receiver domains (FEBS 27785): [FEBS Letters 554 (2003) 231–236]

Published in:

2004

By:

Kojetin, Douglas J.;
Thompson, Richele J.;
Cavanagh, John

Publication type:

Correction Notice

Sub-classification of response regulators using the surface characteristics of their receiver domains

Published in:

FEBS Letters, 2003, v. 554, n. 3, p. 231, doi. 10.1016/S0014-5793(03)01167-0

By:

Kojetin, Douglas J.;
Thompson, Richele J.;
Cavanagh, John

Publication type:

Article

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 8013, doi. 10.1038/ncomms9013

By:

Kojetin, Douglas J.;
Matta-Camacho, Edna;
Hughes, Travis S.;
Srinivasan, Sathish;
Nwachukwu, Jerome C.;
Cavett, Valerie;
Nowak, Jason;
Chalmers, Michael J.;
Marciano, David P.;
Kamenecka, Theodore M.;
Shulman, Andrew I.;
Rance, Mark;
Griffin, Patrick R.;
Bruning, John B.;
Nettles, Kendall W.

Publication type:

Article

Pharmacological repression of PPARγ promotes osteogenesis.

Published in:

Nature Communications, 2015, v. 6, n. 6, p. 7443, doi. 10.1038/ncomms8443

By:

Marciano, David P.;
Kuruvilla, Dana S.;
Boregowda, Siddaraju V.;
Asteian, Alice;
Hughes, Travis S.;
Garcia-Ordonez, Ruben;
Corzo, Cesar A.;
Khan, Tanya M.;
Novick, Scott J.;
Park, HaJeung;
Kojetin, Douglas J.;
Phinney, Donald G.;
Bruning, John B.;
Kamenecka, Theodore M.;
Griffin, Patrick R.

Publication type:

Article

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.

Published in:

Nature Communications, 2014, v. 5, n. 11, p. 5395, doi. 10.1038/ncomms6395

By:

Hudson, William H.;
Pickard, Mark R.;
de Vera, Ian Mitchelle S.;
Kuiper, Emily G.;
Mourtada-Maarabouni, Mirna;
Conn, Graeme L.;
Kojetin, Douglas J.;
Williams, Gwyn T.;
Ortlund, Eric A.

Publication type:

Article

An alternate binding site for PPARγ ligands.

Published in:

Nature Communications, 2014, v. 5, n. 4, p. 3571, doi. 10.1038/ncomms4571

By:

Hughes, Travis S.;
Giri, Pankaj Kumar;
de Vera, Ian Mitchelle S.;
Marciano, David P.;
Kuruvilla, Dana S.;
Shin, Youseung;
Blayo, Anne-Laure;
Kamenecka, Theodore M.;
Burris, Thomas P.;
Griffin, Patrick R.;
Kojetin, Douglas J.

Publication type:

Article

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 14, p. 8596, doi. 10.1093/nar/gkx509

By:

Weikum, Emily R.;
de Vera, Ian Mitchelle S.;
Nwachukwu, Jerome C.;
Hudson, William H.;
Nettles, Kendall W.;
Kojetin, Douglas J.;
Ortlund, Eric A.

Publication type:

Article

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07133-w

By:

Brust, Richard;
Shang, Jinsai;
Fuhrmann, Jakob;
Mosure, Sarah A.;
Bass, Jared;
Cano, Andrew;
Heidari, Zahra;
Chrisman, Ian M.;
Nemetchek, Michelle D.;
Blayo, Anne-Laure;
Griffin, Patrick R.;
Kamenecka, Theodore M.;
Hughes, Travis S.;
Kojetin, Douglas J.

Publication type:

Article

Defining a conformational ensemble that directs activation of PPARγ.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04176-x

By:

Chrisman, Ian M.;
Nemetchek, Michelle D.;
S. de Vera, Ian Mitchelle;
Jinsai Shang;
Heidari, Zahra;
Long, Yanan;
Reyes-Caballero, Hermes;
Galindo-Murillo, Rodrigo;
Cheatham III, Thomas E.;
Blayo, Anne-Laure;
Youseung Shin;
Fuhrmann, Jakob;
Griffin, Patrick R.;
Kamenecka, Theodore M.;
Kojetin, Douglas J.;
Hughes, Travis S.

Publication type:

Article

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03780-1

By:

Hudson, William H.;
de Vera, Ian Mitchelle S.;
Nwachukwu, Jerome C.;
Weikum, Emily R.;
Herbst, Austin G.;
Qin Yang;
Bain, David L.;
Nettles, Kendall W.;
Kojetin, Douglas J.;
Ortlund, Eric A.

Publication type:

Article

The Tat inhibitor didehydro-cortistatin A suppresses SIV replication and reactivation.

Published in:

FASEB Journal, 2019, v. 33, n. 7, p. 8280, doi. 10.1096/fj.201801165R

By:

Mediouni, Sonia;
Kessing, Cari F.;
Jablonski, Joseph A.;
Thenin-Houssier, Suzie;
Clementz, Mark;
Kovach, Melia D.;
Mousseau, Guillaume;
de Vera, Ian Mitchelle S.;
Chuan Li;
Kojetin, Douglas J.;
Evans, David T.;
Valente, Susana T.

Publication type:

Article

DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 556, doi. 10.1038/nsmb.2046

By:

Jun Zhang;
Chalmers, Michael J.;
Stayrook, Keith R.;
Burris, Lorri L.;
Yongjun Wang;
Busby, Scott A.;
Pascal, Bruce D.;
Garcia-Ordonez, Ruben D.;
Bruning, John B.;
Istrate, Monica A.;
Kojetin, Douglas J.;
Dodge, Jeffrey A.;
Burris, Thomas P.;
Griffin, Patrick R.

Publication type:

Article

Structure, binding interface and hydrophobic transitions of Ca<sup>2+</sup>-loaded calbindin-D<sub>28K</sub>.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 7, p. 641, doi. 10.1038/nsmb1112

By:

Kojetin, Douglas J.;
Venters, Ronald A.;
Kordys, David R.;
Thompson, Richele J.;
Kumar, Rajiv;
Cavanagh, John

Publication type:

Article

A molecular switch regulating transcriptional repression and activation of PPARγ.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14750-x

By:

Shang, Jinsai;
Mosure, Sarah A.;
Zheng, Jie;
Brust, Richard;
Bass, Jared;
Nichols, Ashley;
Solt, Laura A.;
Griffin, Patrick R.;
Kojetin, Douglas J.

Publication type:

Article

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134474

By:

Hughes, Travis S.;
Wilson, Henry D.;
de Vera, Ian Mitchelle S.;
Kojetin, Douglas J.

Publication type:

Article

Regulation of p53 Stability and Apoptosis by a ROR Agonist.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034921

By:

Wang, Yongjun;
Solt, Laura A.;
Kojetin, Douglas J.;
Burris, Thomas P.

Publication type:

Article

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.

Published in:

Nature, 2012, v. 485, n. 7396, p. 62, doi. 10.1038/nature11030

By:

Solt, Laura A.;
Wang, Yongjun;
Banerjee, Subhashis;
Hughes, Travis;
Kojetin, Douglas J.;
Lundasen, Thomas;
Shin, Youseung;
Liu, Jin;
Cameron, Michael D.;
Noel, Romain;
Yoo, Seung-Hee;
Takahashi, Joseph S.;
Butler, Andrew A.;
Kamenecka, Theodore M.;
Burris, Thomas P.

Publication type:

Article

Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 5, p. 326, doi. 10.1038/nchembio.1214

By:

Srinivasan, Sathish;
Nwachukwu, Jerome C;
Parent, Alex A;
Cavett, Valerie;
Nowak, Jason;
Hughes, Travis S;
Kojetin, Douglas J;
Katzenellenbogen, John A;
Nettles, Kendall W

Publication type:

Article

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea.

Published in:

FEBS Journal, 2016, v. 283, n. 19, p. 3567, doi. 10.1111/febs.13819

By:

Hepowit, Nathaniel L.;
Vera, Ian Mitchelle S.;
Cao, Shiyun;
Fu, Xian;
Wu, Yifei;
Uthandi, Sivakumar;
Chavarria, Nikita E.;
Englert, Markus;
Su, Dan;
Sӧll, Dieter;
Kojetin, Douglas J.;
Maupin‐Furlow, Julie A.

Publication type:

Article