Works by Koivunen, Peppi

Results: 40

NMR Assignment of the N-terminal Domain a of the Glycoprotein Chaperone ERp57.

Published in:

Journal of Biomolecular NMR, 2005, v. 33, n. 2, p. 136, doi. 10.1007/s10858-005-2720-1

By:

Silvennoinen, Laura;
Koivunen, Peppi;
Myllyharju, Johanna;
Kilpeläinen, Ilkka;
Permi, Perttu

Publication type:

Article

Letter to the Editor: Assignment of 1H, 13C and 15N resonances of the a′ domain of ERp57.

Published in:

Journal of Biomolecular NMR, 2001, v. 20, n. 4, p. 385, doi. 10.1023/A:1011291316810

By:

Silvennoinen, Laura;
Karvonen, Päivi;
Koivunen, Peppi;
Myllyharju, Johanna;
Kivirikko, Kari;
Kilpeläinen, Ilkka

Publication type:

Article

Hypoxia-inducible factor prolyl 4-hydroxylases: common and specific roles.

Published in:

Biological Chemistry, 2013, v. 394, n. 4, p. 435, doi. 10.1515/hsz-2012-0328

By:

Myllyharju, Johanna;
Koivunen, Peppi

Publication type:

Article

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway.

Published in:

FASEB Journal, 2005, v. 19, n. 10, p. 1308, doi. 10.1096/fj.04-3399fje

By:

Hirsilä, Maija;
Koivunen, Peppi;
Xu, Leon;
Seeley, Todd;
Kivirikko, Kari I.;
Myllyharju, Johanna

Publication type:

Article

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Published in:

Nature, 2012, v. 483, n. 7390, p. 484, doi. 10.1038/nature10898

By:

Koivunen, Peppi;
Lee, Sungwoo;
Duncan, Christopher G.;
Lopez, Giselle;
Lu, Gang;
Ramkissoon, Shakti;
Losman, Julie A.;
Joensuu, Päivi;
Bergmann, Ulrich;
Gross, Stefan;
Travins, Jeremy;
Weiss, Samuel;
Looper, Ryan;
Ligon, Keith L.;
Verhaak, Roel G. W.;
Yan, Hai;
Kaelin Jr, William G.

Publication type:

Article

HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC.

Published in:

International Journal of Oncology, 2017, v. 51, n. 2, p. 599, doi. 10.3892/ijo.2017.4048

By:

HONKANEN, TIIA;
WILENIUS, EMMI;
KOIVUNEN, PEPPI;
KOIVUNEN, JUSSI P.

Publication type:

Article

Activation of the hypoxia-inducible factor pathway by roxadustat improves glucose metabolism in human primary myotubes from men.

Published in:

Diabetologia, 2024, v. 67, n. 9, p. 1943, doi. 10.1007/s00125-024-06185-6

By:

Mäkinen, Selina;
Sree, Sreesha;
Ala-Nisula, Tuulia;
Kultalahti, Henric;
Koivunen, Peppi;
Koistinen, Heikki A.

Publication type:

Article

Hypoxia ameliorates maternal diet‐induced insulin resistance during pregnancy while having a detrimental effect on the placenta.

Published in:

Physiological Reports, 2022, v. 10, n. 9, p. 1, doi. 10.14814/phy2.15302

By:

Sissala, Niina;
Myllymäki, Elisa;
Mohr, Florian;
Halmetoja, Riikka;
Kuvaja, Paula;
Dimova, Elitsa Y.;
Koivunen, Peppi

Publication type:

Article

Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice.

Published in:

Molecular & Cellular Biology, 2017, v. 37, n. 2, p. 1, doi. 10.1128/MCB.00529-16

By:

Myllymäki, Mikko N. M.;
Määttä, Jenni;
Dimova, Elitsa Y.;
Izzi, Valerio;
Väisänen, Timo;
Myllyharju, Johanna;
Koivunen, Peppi;
Serpi, Raisa

Publication type:

Article

Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice.

Published in:

Pflügers Archiv: European Journal of Physiology, 2024, v. 476, n. 9, p. 1339, doi. 10.1007/s00424-024-02920-5

By:

Ala-Nisula, Tuulia;
Halmetoja, Riikka;
Leinonen, Henri;
Kurkela, Margareta;
Lipponen, Henna-Riikka;
Sakko, Samuli;
Karpale, Mikko;
Salo, Antti M.;
Sissala, Niina;
Röning, Tapio;
Raza, Ghulam S.;
Mäkelä, Kari A.;
Thevenot, Jérôme;
Herzig, Karl-Heinz;
Serpi, Raisa;
Myllyharju, Johanna;
Tanila, Heikki;
Koivunen, Peppi;
Dimova, Elitsa Y.

Publication type:

Article

Author Correction: Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism.

Published in:

2020

By:

Määttä, Jenni;
Sissala, Niina;
Dimova, Elitsa Y.;
Serpi, Raisa;
Moore, Lorna G.;
Koivunen, Peppi

Publication type:

Correction Notice

Remote ischemic preconditioning and hypoxia-induced biomarkers in acute myocardial infarction: study on a porcine model.

Published in:

Scandinavian Cardiovascular Journal, 2023, v. 57, n. 1, p. 1, doi. 10.1080/14017431.2023.2251730

By:

Anttila, Tuomas;
Herajärvi, Johanna;
Laaksonen, Henna;
Mustonen, Caius;
Honkanen, Hannu-Pekka;
Y. Dimova, Elitsa;
Piuhola, Jarkko;
Koivunen, Peppi;
Juvonen, Tatu;
Anttila, Vesa

Publication type:

Article

Exploring effects of remote ischemic preconditioning in a pig model of hypothermic circulatory arrest.

Published in:

2017

By:

Herajärvi, Johanna;
Anttila, Tuomas;
Dimova, Elitsa Y.;
Laukka, Tuomas;
Myllymäki, Mikko;
Haapanen, Henri;
Olenchock, Benjamin A.;
Tuominen, Hannu;
Puistola, Ulla;
Karihtala, Peeter;
Kiviluoma, Kai;
Koivunen, Peppi;
Anttila, Vesa;
Juvonen, Tatu

Publication type:

journal article

The TET enzymes.

Published in:

Cellular & Molecular Life Sciences, 2018, v. 75, n. 8, p. 1339, doi. 10.1007/s00018-017-2721-8

By:

Koivunen, Peppi;
Laukka, Tuomas

Publication type:

Article

Association of hemoglobin levels with metabolic traits in women with PCOS.

Published in:

Acta Obstetricia et Gynecologica Scandinavica, 2025, v. 104, n. 2, p. 357, doi. 10.1111/aogs.15047

By:

Virtanen, Nikke;
Pesonen, Emilia;
Saarela, Ulla;
Hurskainen, Elisa;
Arffman, Riikka K.;
Koivunen, Peppi;
Piltonen, Terhi

Publication type:

Article

Higher hemoglobin levels are an independent risk factor for gestational diabetes.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05801-y

By:

Sissala, Niina;
Mustaniemi, Sanna;
Kajantie, Eero;
Vääräsmäki, Marja;
Koivunen, Peppi

Publication type:

Article

Higher hemoglobin levels are an independent risk factor for adverse metabolism and higher mortality in a 20-year follow-up.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99217-9

By:

Tapio, Joona;
Vähänikkilä, Hannu;
Kesäniemi, Y. Antero;
Ukkola, Olavi;
Koivunen, Peppi

Publication type:

Article

The acidic C-terminal domain of protein disulfide isomerase is not critical for the enzyme subunit function or for the chaperone or disulfide isomerase activities of the polypeptide.

Published in:

EMBO Journal, 1999, v. 18, n. 1, p. 65, doi. 10.1093/emboj/18.1.65

By:

Koivunen, Peppi;
Pirneskoski, Annamari;
Karvonen, Päivi;
Ljung, Johanna;
Helaakoski, Tarja;
Notbohm, Holger;
Kivirikko, Kari I.

Publication type:

Article

Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 4038, doi. 10.3390/ijms22084038

By:

Dengler, Franziska;
Sova, Sofia;
Salo, Antti M.;
Mäki, Joni M.;
Koivunen, Peppi;
Myllyharju, Johanna

Publication type:

Article

Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31908-2

By:

Määttä, Jenni;
Sissala, Niina;
Dimova, Elitsa Y.;
Serpi, Raisa;
Moore, Lorna G.;
Koivunen, Peppi

Publication type:

Article

Structural basis of homo- and heterotrimerization of collagen I.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14671, doi. 10.1038/ncomms14671

By:

Sharma, Urvashi;
Carrique, Loïc;
Vadon-Le Goff, Sandrine;
Mariano, Natacha;
Georges, Rainier-Numa;
Delolme, Frederic;
Koivunen, Peppi;
Myllyharju, Johanna;
Moali, Catherine;
Aghajari, Nushin;
Hulmes, David J. S.

Publication type:

Article

Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism.

Published in:

FEBS Letters, 2023, v. 597, n. 12, p. 1651, doi. 10.1002/1873-3468.14666

By:

Ala‐Nisula, Tuulia;
Sah‐Teli, Shiv K.;
Ronkainen, Veli‐Pekka;
Dimova, Elitsa Y.;
Koivunen, Peppi

Publication type:

Article

HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD.

Published in:

Journal of Molecular Medicine, 2020, v. 98, n. 5, p. 719, doi. 10.1007/s00109-020-01903-0

By:

Laitakari, Anna;
Tapio, Joona;
Mäkelä, Kari A.;
Herzig, Karl-Heinz;
Dengler, Franziska;
Gylling, Helena;
Walkinshaw, Gail;
Myllyharju, Johanna;
Dimova, Elitsa Y.;
Serpi, Raisa;
Koivunen, Peppi

Publication type:

Article

HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.

Published in:

Journal of Molecular Medicine, 2016, v. 94, n. 3, p. 301, doi. 10.1007/s00109-015-1349-0

By:

Karsikas, Sara;
Myllymäki, Mikko;
Heikkilä, Minna;
Sormunen, Raija;
Kivirikko, Kari;
Myllyharju, Johanna;
Serpi, Raisa;
Koivunen, Peppi

Publication type:

Article

Lack of P4H-TM in mice results in age-related retinal and renal alterations.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 17, p. 3810, doi. 10.1093/hmg/ddw228

By:

Leinonen, Henri;
Rossi, Maarit;
Salo, Antti M.;
Tiainen, Päaivi;
Hyväarinen, Jaana;
Pitkäanen, Marja;
Sormunen, Raija;
Miinalainen, Ilkka;
Chi Zhang;
Soininen, Raija;
Kivirikko, Kari I.;
Koskelainen, Ari;
Tanila, Heikki;
Myllyharju, Johanna;
Koivunen, Peppi

Publication type:

Article

A novel treatment strategy for EGFR mutant NSCLC with T790M-mediated acquired resistance.

Published in:

International Journal of Cancer, 2012, v. 131, n. 4, p. 970, doi. 10.1002/ijc.26461

By:

Taube, Erika;
Jokinen, Elina;
Koivunen, Peppi;
Koivunen, Jussi P.

Publication type:

Article

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13889-6

By:

D'Hulst, Gommaar;
Soro-Arnaiz, Inés;
Masschelein, Evi;
Veys, Koen;
Fitzgerald, Gillian;
Smeuninx, Benoit;
Kim, Sunghoon;
Deldicque, Louise;
Blaauw, Bert;
Carmeliet, Peter;
Breen, Leigh;
Koivunen, Peppi;
Zhao, Shi-Min;
De Bock, Katrien

Publication type:

Article

Activation of the hypoxia response protects mice from amyloid-β accumulation.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 8, p. 1, doi. 10.1007/s00018-022-04460-6

By:

Ollonen, Teemu;
Kurkela, Margareta;
Laitakari, Anna;
Sakko, Samuli;
Koivisto, Henna;
Myllyharju, Johanna;
Tanila, Heikki;
Serpi, Raisa;
Koivunen, Peppi

Publication type:

Article

Higher haemoglobin levels are associated with impaired periodontal status.

Published in:

Journal of Clinical Periodontology, 2024, v. 51, n. 9, p. 1168, doi. 10.1111/jcpe.14030

By:

Tapiola, Atte;
Tapio, Joona;
Vähänikkilä, Hannu;
Tegelberg, Paula;
Ylöstalo, Pekka;
Koivunen, Peppi

Publication type:

Article

Elevated protein carbonyl and HIF-1α levels in eyes with proliferative diabetic retinopathy.

Published in:

Acta Ophthalmologica (1755375X), 2014, v. 92, n. 4, p. 323, doi. 10.1111/aos.12186

By:

Loukovaara, Sirpa;
KoivunEN, Peppi;
Inglés, Marta;
Escobar, Javier;
VENto, Maximo;
Andersson, Sture

Publication type:

Article

Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice.

Published in:

PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0233261

By:

Settelmeier, Stephan;
Schreiber, Timm;
Mäki, Joni;
Byts, Nadiya;
Koivunen, Peppi;
Myllyharju, Johanna;
Fandrey, Joachim;
Winning, Sandra

Publication type:

Article

HIF-1α is upregulated in human mesenchymal stem cells.

Published in:

Stem Cells, 2013, v. 31, n. 9, p. 1902, doi. 10.1002/stem.1435

By:

Palomäki, Sami;
Pietilä, Mika;
Laitinen, Saara;
Pesälä, Juha;
Sormunen, Raija;
Lehenkari, Petri;
Koivunen, Peppi

Publication type:

Article

Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 16, p. 3321, doi. 10.1128/MCB.00432-13

By:

Kerkelä, Risto;
Karsikas, Sara;
Szabo, Zoltan;
Serpi, Raisa;
Magga, Johanna;
Gao, Erhe;
Alitalo, Kari;
Anisimov, Andrey;
Sormunen, Raija;
Pietilä, Ilkka;
Vainio, Laura;
Koch, Walter J.;
Kivirikko, Kari I.;
Myllyharju, Johanna;
Koivunen, Peppi

Publication type:

Article

Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 15, p. 3321, doi. 10.1128/MCB.00432-13

By:

Kerkelä, Risto;
Karsikas, Sara;
Szabo, Zoltan;
Serpi, Raisa;
Magga, Johanna;
Gao, Erhe;
Alitalo, Kari;
Anisimov, Andrey;
Sormunen, Raija;
Pietilä, Ilkka;
Vainio, Laura;
Koch, Walter J.;
Kivirikko, Kari I.;
Myllyharju, Johanna;
Koivunen, Peppi

Publication type:

Article

Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients.

Published in:

Breast Cancer Research & Treatment, 2012, v. 133, n. 1, p. 179, doi. 10.1007/s10549-011-1750-5

By:

Peurala, Emmi;
Koivunen, Peppi;
Bloigu, Risto;
Haapasaari, Kirsi-Maria;
Jukkola-Vuorinen, Arja

Publication type:

Article

Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.

Published in:

eNeuro, 2021, v. 8, n. 1, p. 1, doi. 10.1523/ENEURO.0253-20.2020

By:

Byts, Nadiya;
Sharma, Subodh;
Laurila, Jenny;
Paudel, Prodeep;
Miinalainen, Ilkka;
Ronkainen, Veli-Pekka;
Hinttala, Reetta;
Törnquist, Kid;
Koivunen, Peppi;
Myllyharju, Johanna

Publication type:

Article

The prognostic significance and value of cyclin D1, CDK4 and p16 in human breast cancer.

Published in:

Breast Cancer Research, 2013, v. 15, n. 1, p. 1, doi. 10.1186/bcr3376

By:

Peurala, Emmi;
Koivunen, Peppi;
Haapasaari, Kirsi-Maria;
Bloigu, Risto;
Jukkola-Vuorinen, Arja

Publication type:

Article

Mutations in domain a′ of protein disulfide isomerase affect the folding pathway of bovine pancreatic ribonuclease A.

Published in:

Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 5, p. 939, doi. 10.1110/ps.0242803

By:

Ruoppolo, Margherita;
Orrù, Stefania;
Talamo, Fabio;
Ljung, Johanna;
Pirneskoski, Annamari;
Kivirikko, Kari I.;
Marino, Gennaro;
Koivunen, Peppi

Publication type:

Article

Systemic long‐term inactivation of hypoxia‐inducible factor prolyl 4‐hydroxylase 2 ameliorates aging‐induced changes in mice without affecting their life span.

Published in:

FASEB Journal, 2020, v. 34, n. 4, p. 5590, doi. 10.1096/fj.201902331R

By:

Laitakari, Anna;
Huttunen, Riikka;
Kuvaja, Paula;
Hannuksela, Pauliina;
Szabo, Zoltan;
Heikkilä, Minna;
Kerkelä, Risto;
Myllyharju, Johanna;
Dimova, Elitsa Y.;
Serpi, Raisa;
Koivunen, Peppi

Publication type:

Article

HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction.

Published in:

Diabetes, 2014, v. 63, n. 10, p. 3324, doi. 10.2337/db14-0472

By:

Rahtu-Korpela, Lea;
Karsikas, Sara;
Hörkkö, Sohvi;
Blanco Sequeiros, Roberto;
Lammentausta, Eveliina;
Mäkelä, Kari A.;
Herzig, Karl-Heinz;
Walkinshaw, Gail;
Kivirikko, Kari I.;
Myllyharju, Johanna;
Serpi, Raisa;
Koivunen, Peppi

Publication type:

Article