Works matching AU Koike, Tatsuki

Results: 13

TAK-861, a potent, orally available orexin receptor 2-selective agonist, produces wakefulness in monkeys and improves narcolepsy-like phenotypes in mouse models.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-70594-1

By:

Mitsukawa, Kayo;
Terada, Michiko;
Yamada, Ryuji;
Monjo, Taku;
Hiyoshi, Tetsuaki;
Nakakariya, Masanori;
Kajita, Yuichi;
Ando, Tatsuya;
Koike, Tatsuki;
Kimura, Haruhide

Publication type:

Article

Molecular mechanism of the wake-promoting agent TAK-925.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30601-3

By:

Yin, Jie;
Kang, Yanyong;
McGrath, Aaron P.;
Chapman, Karen;
Sjodt, Megan;
Kimura, Eiji;
Okabe, Atsutoshi;
Koike, Tatsuki;
Miyanohana, Yuhei;
Shimizu, Yuji;
Rallabandi, Rameshu;
Lian, Peng;
Bai, Xiaochen;
Flinspach, Mack;
De Brabander, Jef K.;
Rosenbaum, Daniel M.

Publication type:

Article

Quantification of monoacylglycerol lipase and its occupancy by an exogenous ligand in rhesus monkey brains using [ 18 F]T-401 and PET.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 4, p. 656, doi. 10.1177/0271678X211058285

By:

Hattori, Yasushi;
Seki, Chie;
Maeda, Jun;
Nagai, Yuji;
Aoyama, Kazunobu;
Zhang, Ming-Rong;
Minamimoto, Takafumi;
Koike, Tatsuki;
Higuchi, Makoto

Publication type:

Article

Preclinical characterization of [<sup>18</sup>F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 4, p. 1148, doi. 10.1007/s00259-021-05565-z

By:

Koike, Tatsuki;
Constantinescu, Cristian C.;
Ikeda, Shuhei;
Nishi, Toshiya;
Sunahara, Eiji;
Miyamoto, Maki;
Cole, Patricia;
Barret, Olivier;
Alagille, David;
Papin, Caroline;
Morley, Thomas;
Fowles, Krista;
Seibyl, John;
Tamagnan, Gilles;
Kuroita, Takanobu

Publication type:

Article

Reply to: The G protein preference of orexin receptors is currently an unresolved issue.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38765-2

By:

Yin, Jie;
Kang, Yanyong;
McGrath, Aaron P.;
Chapman, Karen;
Sjodt, Megan;
Kimura, Eiji;
Okabe, Atsutoshi;
Koike, Tatsuki;
Miyanohana, Yuhei;
Shimizu, Yuji;
Rallabandi, Rameshu;
Lian, Peng;
Bai, Xiaochen;
Flinspach, Mack;
De Brabander, Jef K.;
Rosenbaum, Daniel M.

Publication type:

Article

Innenrücktitelbild: Synthesis of Low‐Molecular‐Weight Fucoidan Analogue and Its Inhibitory Activities against Heparanase and SARS‐CoV‐2 Infection (Angew. Chem. 6/2025).

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202423694

By:

Sugimoto, Aoi;
Koike, Tatsuki;
Kuboki, Yuya;
Komaba, Sumika;
Kosono, Shuhei;
Aswathy, Maniyamma;
Anzai, Itsuki;
Watanabe, Tokiko;
Toshima, Kazunobu;
Takahashi, Daisuke

Publication type:

Article

Synthesis of Low‐Molecular‐Weight Fucoidan Analogue and Its Inhibitory Activities against Heparanase and SARS‐CoV‐2 Infection.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202411760

By:

Sugimoto, Aoi;
Koike, Tatsuki;
Kuboki, Yuya;
Komaba, Sumika;
Kosono, Shuhei;
Aswathy, Maniyamma;
Anzai, Itsuki;
Watanabe, Tokiko;
Toshima, Kazunobu;
Takahashi, Daisuke

Publication type:

Article

Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0306099

By:

Yamada, Ryuji;
Koike, Tatsuki;
Nakakariya, Masanori;
Kimura, Haruhide

Publication type:

Article

Pharmacological Characterization of a Highly Selective and Potent Partial Agonist of the MT<sub>2</sub> Melatonin Receptor.

Published in:

Pharmacology, 2014, v. 93, n. 5/6, p. 244, doi. 10.1159/000362561

By:

Sakurai, Taku;
Koike, Tatsuki;
Nakayama, Masaharu

Publication type:

Article

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74036-6

By:

Nishi, Toshiya;
Kondo, Shinichi;
Miyamoto, Maki;
Watanabe, Sayuri;
Hasegawa, Shigeo;
Kondo, Shigeru;
Yano, Jason;
Watanabe, Etsurou;
Ishi, Tsuyoshi;
Yoshikawa, Masato;
Ando, Haruhi Kamisaki;
Farnaby, William;
Fujimoto, Shinji;
Sunahara, Eiji;
Ohori, Momoko;
During, Matthew J.;
Kuroita, Takanobu;
Koike, Tatsuki

Publication type:

Article

Pharmacologic properties of compound-1, a novel and orally active γ-secretase modulator, as a therapeutic option for the treatment of Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P844, doi. 10.1016/j.jalz.2015.06.1878

By:

Murakami, Koji;
Watanabe, Tomomichi;
Koike, Tatsuki;
Kamata, Makoto;
Igari, Tomoko;
Kondou, Shinichi

Publication type:

Article

Inside Back Cover: Synthesis of Low‐Molecular‐Weight Fucoidan Analogue and Its Inhibitory Activities against Heparanase and SARS‐CoV‐2 Infection (Angew. Chem. Int. Ed. 6/2025).

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202423694

By:

Sugimoto, Aoi;
Koike, Tatsuki;
Kuboki, Yuya;
Komaba, Sumika;
Kosono, Shuhei;
Aswathy, Maniyamma;
Anzai, Itsuki;
Watanabe, Tokiko;
Toshima, Kazunobu;
Takahashi, Daisuke

Publication type:

Article

Synthesis of Low‐Molecular‐Weight Fucoidan Analogue and Its Inhibitory Activities against Heparanase and SARS‐CoV‐2 Infection.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202411760

By:

Sugimoto, Aoi;
Koike, Tatsuki;
Kuboki, Yuya;
Komaba, Sumika;
Kosono, Shuhei;
Aswathy, Maniyamma;
Anzai, Itsuki;
Watanabe, Tokiko;
Toshima, Kazunobu;
Takahashi, Daisuke

Publication type:

Article