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Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR.
Published in:
Membranes, 2021, v. 11, n. 8, p. 604, doi. 10.3390/membranes11080604
By:
- Takeuchi, Koh;
- Kofuku, Yutaka;
- Imai, Shunsuke;
- Ueda, Takumi;
- Tokunaga, Yuji;
- Toyama, Yuki;
- Shiraishi, Yutaro;
- Shimada, Ichio
Publication type:
Article
Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ‐Opioid Receptor.
Published in:
Angewandte Chemie International Edition, 2015, v. 54, n. 52, p. 15771, doi. 10.1002/anie.201508794
By:
- Okude, Junya;
- Ueda, Takumi;
- Kofuku, Yutaka;
- Sato, Motohiko;
- Nobuyama, Naoyuki;
- Kondo, Keita;
- Shiraishi, Yutaro;
- Mizumura, Takuya;
- Onishi, Kento;
- Natsume, Mei;
- Maeda, Masahiro;
- Tsujishita, Hideki;
- Kuranaga, Takefumi;
- Inoue, Masayuki;
- Shimada, Ichio
Publication type:
Article
Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the µ-Opioid Receptor.
Published in:
Angewandte Chemie International Edition, 2015, v. 54, n. 52, p. 15771, doi. 10.1002/anie.201508794
By:
- Okude, Junya;
- Ueda, Takumi;
- Kofuku, Yutaka;
- Sato, Motohiko;
- Nobuyama, Naoyuki;
- Kondo, Keita;
- Shiraishi, Yutaro;
- Mizumura, Takuya;
- Onishi, Kento;
- Natsume, Mei;
- Maeda, Masahiro;
- Tsujishita, Hideki;
- Kuranaga, Takefumi;
- Inoue, Masayuki;
- Shimada, Ichio
Publication type:
Article
Functional Dynamics of Deuterated β2-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 49, p. 13376, doi. 10.1002/anie.201406603
By:
- Kofuku, Yutaka;
- Ueda, Takumi;
- Okude, Junya;
- Shiraishi, Yutaro;
- Kondo, Keita;
- Mizumura, Takuya;
- Suzuki, Shiho;
- Shimada, Ichio
Publication type:
Article
Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.
Published in:
Biochemical Journal, 2014, v. 457, n. 2, p. 313, doi. 10.1042/BJ20130827
By:
- Etsuko TODA;
- Yuya TERASHIMA;
- Kaori ESAKI;
- Sosuke YOSHINAGA;
- Minoru SUGIHARA;
- Yutaka KOFUKU;
- Ichio SHIMADA;
- Makiko SUWA;
- Shiro KANEGASAKI;
- Hiroaki TERASAWA;
- Kouji MATSUSHIMA
Publication type:
Article
Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27482-3
By:
- Shiraishi, Yutaro;
- Kofuku, Yutaka;
- Ueda, Takumi;
- Pandey, Shubhi;
- Dwivedi-Agnihotri, Hemlata;
- Shukla, Arun K.;
- Shimada, Ichio
Publication type:
Article
Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor.
Published in:
Angewandte Chemie, 2015, v. 127, n. 52, p. 15997, doi. 10.1002/ange.201508794
By:
- Junya Okude;
- Takumi Ueda;
- Yutaka Kofuku;
- Motohiko Sato;
- Naoyuki Nobuyama;
- Keita Kondo;
- Yutaro Shiraishi;
- Takuya Mizumura;
- Kento Onishi;
- Mei Natsume;
- Masahiro Maeda;
- Hideki Tsujishita;
- Takefumi Kuranaga;
- Masayuki Inoue;
- Ichio Shimada
Publication type:
Article
Functional Dynamics of Deuterated β2-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy.
Published in:
Angewandte Chemie, 2014, v. 126, n. 49, p. 13594, doi. 10.1002/ange.201406603
By:
- Kofuku, Yutaka;
- Ueda, Takumi;
- Okude, Junya;
- Shiraishi, Yutaro;
- Kondo, Keita;
- Mizumura, Takuya;
- Suzuki, Shiho;
- Shimada, Ichio
Publication type:
Article
Utilization of paramagnetic relaxation enhancements for structural analysis of actin-binding proteins in complex with actin.
Published in:
Scientific Reports, 2016, p. 33690, doi. 10.1038/srep33690
By:
- Huang, Shuxian;
- Umemoto, Ryo;
- Tamura, Yuki;
- Kofuku, Yutaka;
- Uyeda, Taro Q. P.;
- Nishida, Noritaka;
- Shimada, Ichio
Publication type:
Article
Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system.
Published in:
Journal of Biomolecular NMR, 2018, v. 71, n. 3, p. 185, doi. 10.1007/s10858-018-0174-5
By:
- Kofuku, Yutaka;
- Yokomizo, Tomoki;
- Imai, Shunsuke;
- Shiraishi, Yutaro;
- Natsume, Mei;
- Itoh, Hiroaki;
- Inoue, Masayuki;
- Nakata, Kunio;
- Igarashi, Shunsuke;
- Yamaguchi, Hideyuki;
- Mizukoshi, Toshimi;
- Suzuki, Ei-ichiro;
- Ueda, Takumi;
- Shimada, Ichio
Publication type:
Article
Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments.
Published in:
Journal of Biomolecular NMR, 2015, v. 63, n. 4, p. 333, doi. 10.1007/s10858-015-9992-x
By:
- Yoshiura, Chie;
- Ueda, Takumi;
- Kofuku, Yutaka;
- Matsumoto, Masahiko;
- Okude, Junya;
- Kondo, Keita;
- Shiraishi, Yutaro;
- Shimada, Ichio
Publication type:
Article
Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data.
Published in:
Journal of Biomolecular NMR, 2015, v. 62, n. 1, p. 31, doi. 10.1007/s10858-015-9908-9
By:
- Ueda, Takumi;
- Yoshiura, Chie;
- Matsumoto, Masahiko;
- Kofuku, Yutaka;
- Okude, Junya;
- Kondo, Keita;
- Shiraishi, Yutaro;
- Takeuchi, Koh;
- Shimada, Ichio
Publication type:
Article
Cross-saturation and transferred cross-saturation experiments.
Published in:
Quarterly Reviews of Biophysics, 2014, v. 47, n. 2, p. 143, doi. 10.1017/S0033583514000043
By:
- Ueda, Takumi;
- Takeuchi, Koh;
- Nishida, Noritaka;
- Stampoulis, Pavlos;
- Kofuku, Yutaka;
- Osawa, Masanori;
- Shimada, Ichio
Publication type:
Article
Phosphorylation-induced conformation of β2- adrenoceptor related to arrestin recruitment revealed by NMR.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02632-8
By:
- Yutaro Shiraishi;
- Mei Natsume;
- Yutaka Kofuku;
- Shunsuke Imai;
- Kunio Nakata;
- Toshimi Mizukoshi;
- Takumi Ueda;
- Hideo Iwaï;
- Ichio Shimada
Publication type:
Article
High-throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy.
Published in:
Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 5, p. 1115, doi. 10.1002/pro.92
By:
- Sugiki, Toshihiko;
- Yoshiura, Chie;
- Kofuku, Yutaka;
- Ueda, Takumi;
- Shimada, Ichio;
- Takahashi, Hideo
Publication type:
Article
Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14338-5
By:
- Terashima, Yuya;
- Toda, Etsuko;
- Itakura, Meiji;
- Otsuji, Mikiya;
- Yoshinaga, Sosuke;
- Okumura, Kazuhiro;
- Shand, Francis H. W.;
- Komohara, Yoshihiro;
- Takeda, Mitsuhiro;
- Kokubo, Kana;
- Chen, Ming-Chen;
- Yokoi, Sana;
- Rokutan, Hirofumi;
- Kofuku, Yutaka;
- Ohnishi, Koji;
- Ohira, Miki;
- Iizasa, Toshihiko;
- Nakano, Hirofumi;
- Okabe, Takayoshi;
- Kojima, Hirotatsu
Publication type:
Article

Found: 16

Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR.

Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ‐Opioid Receptor.

Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the µ-Opioid Receptor.

Functional Dynamics of Deuterated β<sub>2</sub>-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy.

Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.

Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR.

Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor.

Functional Dynamics of Deuterated β<sub>2</sub>-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy.

Utilization of paramagnetic relaxation enhancements for structural analysis of actin-binding proteins in complex with actin.

Deuteration and selective labeling of alanine methyl groups of β<sub>2</sub>-adrenergic receptor expressed in a baculovirus-insect cell expression system.

Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments.

Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data.

Cross-saturation and transferred cross-saturation experiments.

Phosphorylation-induced conformation of β<sub>2</sub>- adrenoceptor related to arrestin recruitment revealed by NMR.

High-throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy.

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.