Works by Koeffler, H. Phillip

Results: 196

Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor.

Published in:

Nature, 1986, v. 323, n. 6083, p. 79, doi. 10.1038/323079a0

By:

Munker, Reinhold;
Gasson, Judith;
Ogawa, Makio;
Koeffler, H. Phillip

Publication type:

Article

Human p53 gene localized to short arm of chromosome 17.

Published in:

Nature, 1986, v. 319, n. 6056, p. 783, doi. 10.1038/319783a0

By:

Miller, Carl;
Mohandas, T.;
Wolf, D.;
Prokocimer, M.;
Rotter, V.;
Phillip Koeffler, H.

Publication type:

Article

Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer.

Published in:

2010

By:

Iwanski, Gabriela B;
Lee, Dhong H;
En-Gal, Shlomit;
Doan, Ngan B;
Castor, Brandon;
Vogt, Marco;
Toh, Melvin;
Bokemeyer, Carsten;
Said, Jonathan W;
Thoennissen, Nils H;
Koeffler, H Phillip

Publication type:

journal article

The molecular biology of differentiation and proliferation using human myelogenous leukemia cells.

Published in:

BioEssays, 1986, v. 5, n. 1, p. 18, doi. 10.1002/bies.950050106

By:

Miller, Carl;
Koeffler, H. Phillip

Publication type:

Article

Mutational profiling of acute lymphoblastic leukemia with testicular relapse.

Published in:

Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-017-0434-y

By:

Ling-Wen Ding;
Qiao-Yang Sun;
Anand Mayakonda;
Kar-Tong Tan;
Wenwen Chien;
De-Chen Lin;
Yan-Yi Jiang;
Liang Xu;
Manoj Garg;
Zhen-Tang Lao;
Michael Lill;
Henry Yang;
Allen Eng Juh Yeoh;
Koeffler, H. Phillip

Publication type:

Article

Low Plasma Level of Cathelicidin Antimicrobial Peptide (hCAP18) Predicts Increased Infectious Disease Mortality in Patients Undergoing Hemodialysis.

Published in:

Clinical Infectious Diseases, 2009, v. 48, n. 4, p. 418, doi. 10.1086/596314

By:

Gombart, Adrian F.;
Bhan, Ishir;
Borregaard, Niels;
Tamez, Hector;
Camargo, Jr., Carlos A.;
Koeffler, H. Phillip;
Thadhani, Ravi

Publication type:

Article

Targeting genetic lesions in esophageal cancer.

Published in:

Cell Cycle, 2014, v. 13, n. 13, p. 2013, doi. 10.4161/cc.29458

By:

De-Chen Lin;
Ming-Rong Wang;
Koeffler, H. Phillip

Publication type:

Article

Characteristics and predictors of post-transplant-associated hemophagocytic lymphohistiocytosis in adults.

Published in:

International Journal of Hematology, 2021, v. 113, n. 5, p. 693, doi. 10.1007/s12185-020-03067-6

By:

Hattori, Norimichi;
Sato, Misuzu;
Uesugi, Yuka;
Nakata, Ayaka;
Sasaki, Yohei;
Shimada, Shotaro;
Watanuki, Megumi;
Fujiwara, Shun;
Kawaguchi, Yukiko;
Arai, Nana;
Uto, Yui;
Matsui, Tomoharu;
Yanagisawa, Kouji;
Tahara, Sachiko;
Koeffler, H Phillip;
Iezumi, Keiichi;
Nakamaki, Tsuyoshi

Publication type:

Article

Expression of bactericidal/permeability-increasing protein requires C/EBP epsilon.

Published in:

2007

By:

Tanaka, Miyuki;
Gombart, Adrian;
Koeffler, H.;
Shiohara, Masaaki;
Gombart, Adrian F;
Koeffler, H Phillip

Publication type:

journal article

Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.

Published in:

2003

By:

Mori, Naoki;
Yang, Rong;
Kawamata, Norihiko;
Miller, Carl W;
Mizoguchi, Hideaki;
Koeffler, H Phillip

Publication type:

journal article

Important features of myelodysplastic syndrome.

Published in:

2002

By:

Hofmann, Wolf K;
Koeffler, H Phillip

Publication type:

journal article

Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer.

Published in:

Molecular Oncology, 2015, v. 9, n. 4, p. 889, doi. 10.1016/j.molonc.2015.01.002

By:

Chien, Wenwen;
Sun, Qiao-Yang;
Lee, Kian Leong;
Ding, Ling-Wen;
Wuensche, Peer;
Torres-Fernandez, Lucia A.;
Tan, Siew Zhuan;
Tokatly, Itay;
Zaiden, Norazean;
Poellinger, Lorenz;
Mori, Seiichi;
Yang, Henry;
Tyner, Jeffrey W.;
Koeffler, H. Phillip

Publication type:

Article

Circular RNA MAPK4 (circ-MAPK4) inhibits cell apoptosis via MAPK signaling pathway by sponging miR-125a-3p in gliomas.

Published in:

Molecular Cancer, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12943-019-1120-1

By:

He, Jiehua;
Huang, Zuoyu;
He, Mingliang;
Liao, Jianyou;
Zhang, Qianqian;
Wang, Shengwen;
Xie, Lin;
Ouyang, Leping;
Koeffler, H. Phillip;
Yin, Dong;
Liu, Anmin

Publication type:

Article

Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo.

Published in:

Cancer Science, 2008, v. 99, n. 9, p. 1793, doi. 10.1111/j.1349-7006.2008.00899.x

By:

Wakimoto, Naoki;
Yin, Dong;
O’Kelly, James;
Haritunians, Talin;
Karlan, Beth;
Said, Jonathan;
Xing, Hongtao;
Koeffler, H. Phillip

Publication type:

Article

ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib.

Published in:

Cancer Science, 2006, v. 97, n. 12, p. 1404, doi. 10.1111/j.1349-7006.2006.00325.x

By:

Yang, Yang;
Ikezoe, Takayuki;
Nishioka, Chie;
Taguchi, Takahiro;
Zhu, Wei-guo;
Koeffler, H. Phillip;
Taguchi, Hirokuni

Publication type:

Article

Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: Enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling.

Published in:

Cancer Science, 2006, v. 97, n. 9, p. 945, doi. 10.1111/j.1349-7006.2006.00263.x

By:

Ikezoe, Takayuki;
Yang, Yang;
Nishioka, Chie;
Bandobashi, Kentaro;
Nakatani, Hajime;
Taguchi, Takahiro;
Koeffler, H. Phillip;
Taguchi, Hirokuni

Publication type:

Article

HIV-1 protease inhibitor induces growth arrest and apoptosis of human prostate cancer LNCaP cells in vitro and in vivo in conjunction with blockade of androgen receptor STAT3 and AKT signaling.

Published in:

Cancer Science, 2005, v. 96, n. 7, p. 425, doi. 10.1111/j.1349-7006.2005.00063.x

By:

Yang Yang;
Ikezoe, Takayuki;
Takeuchi, Tamotsu;
Adachi, Yoshihiro;
Ohtsuki, Yuji;
Takeuchi, Seisho;
Koeffler, H. Phillip;
Taguchi, Hirokuni

Publication type:

Article

Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells.

Published in:

Cancer Science, 2004, v. 95, n. 3, p. 271, doi. 10.1111/j.1349-7006.2004.tb02215.x

By:

Ikezoe, Takayuki;
Yang, Yang;
Saito, Tsuyako;
Koeffler, H. Phillip;
Taguchi, Hirokuni

Publication type:

Article

Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling.

Published in:

Cancer Science, 2004, v. 95, n. 2, p. 176, doi. 10.1111/j.1349-7006.2004.tb03200.x

By:

Yang, Yang;
Ikezoe, Takeyuki;
Saito, Tsuyako;
Kobayashi, Makoto;
Koeffler, H. Phillip;
Taguchi, Hirokuni

Publication type:

Article

Distinct and convergent consequences of splice factor mutations in myelodysplastic syndromes.

Published in:

American Journal of Hematology, 2020, v. 95, n. 2, p. 133, doi. 10.1002/ajh.25673

By:

Madan, Vikas;
Li, Jia;
Zhou, Siqin;
Teoh, Weoi Woon;
Han, Lin;
Meggendorfer, Manja;
Malcovati, Luca;
Cazzola, Mario;
Ogawa, Seishi;
Haferlach, Torsten;
Yang, Henry;
Koeffler, H. Phillip

Publication type:

Article

Novel CUX1 missense mutation in association with 7q− at leukemic transformation of MPN.

Published in:

American Journal of Hematology, 2011, v. 86, n. 8, p. 703, doi. 10.1002/ajh.22069

By:

Thoennissen, Nils H.;
Lasho, Terra;
Thoennissen, Gabriela B.;
Ogawa, Seishi;
Tefferi, Ayalew;
Koeffler, H. Phillip

Publication type:

Article

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27599-5

By:

Dinh, Huy Q.;
Pan, Feng;
Wang, Geng;
Huang, Qing-Feng;
Olingy, Claire E.;
Wu, Zhi-Yong;
Wang, Shao-Hong;
Xu, Xin;
Xu, Xiu-E;
He, Jian-Zhong;
Yang, Qian;
Orsulic, Sandra;
Haro, Marcela;
Li, Li-Yan;
Huang, Guo-Wei;
Breunig, Joshua J.;
Koeffler, H. Phillip;
Hedrick, Catherine C.;
Xu, Li-Yan;
Lin, De-Chen

Publication type:

Article

Publisher Correction: A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes.

Published in:

2021

By:

Zheng, Yueyuan;
Huang, Guowei;
Silva, Tiago C.;
Yang, Qian;
Jiang, Yan-Yi;
Koeffler, H. Phillip;
Lin, De-Chen;
Berman, Benjamin P.

Publication type:

Correction Notice

A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22720-0

By:

Zheng, Yueyuan;
Huang, Guowei;
Silva, Tiago C.;
Yang, Qian;
Jiang, Yan-Yi;
Koeffler, H. Phillip;
Lin, De-Chen;
Berman, Benjamin P.

Publication type:

Article

Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma.

Published in:

Leukemia & Lymphoma, 2012, v. 53, n. 8, p. 1577, doi. 10.3109/10428194.2012.658792

By:

Thoennissen, Nils H.;
Thoennissen, Gabriela B.;
Abbassi, Sam;
Nabavi-Nouis, Shayan;
Sauer, Tim;
Doan, Ngan B.;
Gery, Sigal;
Müller-Tidow, Carsten;
Said, Jonathan W.;
Koeffler, H. Phillip

Publication type:

Article

Altered Apoptosis Pathways in Mantle Cell Lymphoma.

Published in:

Leukemia & Lymphoma, 2004, v. 45, n. 1, p. 49, doi. 10.1080/1042819031000151112

By:

Rummel, Mathias J.;
De Vos, Sven;
Hoelzer, Dieter;
Koeffler, H. Phillip;
Hofmann, Wolf-K.

Publication type:

Article

Mutations in the Retinoblastoma-related Gene RB2/p130 in Adult T-Cell Leukaemia/Lymphoma.

Published in:

Leukemia & Lymphoma, 2003, v. 44, n. 4, p. 699, doi. 10.1080/1042819031000063480

By:

Takeuchi, Seisho;
Takeuchi, Naoko;
Tsukasaki, Kunihiro;
Fermin, Anthony C.;
De Vas, Sven;
Seo, Hiromi;
Koeffler, H. Phillip

Publication type:

Article

Methylation Analysis of Cell Cycle Control Genes in Adult T-Cell Leukemia/Lymphoma.

Published in:

Leukemia & Lymphoma, 2001, v. 42, n. 5, p. 1107, doi. 10.3109/10428190109097731

By:

Hofmann, Wolf-Karsten;
Tsukasaki, Kunihiro;
Takeuchi, Naoko;
Takeuchi, Seisho;
Koeffler, H. Phillip

Publication type:

Article

Analysis of the CHK2 Gene in Lymphoid Malignancies.

Published in:

Leukemia & Lymphoma, 2001, v. 42, n. 3, p. 517, doi. 10.3109/10428190109064610

By:

Tavor[*], Sigal;
Takeuchi, Seisho;
Tsukasaki, Kunihiro;
Miller, Carl W.;
Hofmann, Wolf-K.;
Ikezoe, Takayuki;
Said, Jonathan W.;
Koeffler, H. Phillip

Publication type:

Article

p21WAF1 Mutations and human malignancies.

Published in:

Leukemia & Lymphoma, 1997, v. 26, n. 1/2, p. 35, doi. 10.3109/10428199709109155

By:

Shiohara, Masaaki;
Koike, Kenichi;
Komiyama, Atsushi;
Koeffler, H. Phillip

Publication type:

Article

Preadipocytes stimulate breast cancer cell growth.

Published in:

Nutrition & Cancer, 1998, v. 32, n. 2, p. 59, doi. 10.1080/01635589809514719

By:

Chamras, Hilda;
Bagga, Dilprit;
Elstner, Elena;
Setoodeh, Katie;
Koeffler, H. Phillip;
Heber, David

Publication type:

Article

Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor.

Published in:

PLoS ONE, 2020, v. 15, n. 6, p. 1, doi. 10.1371/journal.pone.0232068

By:

Lim, Su-Lin;
Xu, Liang;
Han, Bing-Chen;
Shyamsunder, Pavithra;
Chng, Wee-Joo;
Koeffler, H. Phillip

Publication type:

Article

Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.

Published in:

RNA Biology, 2021, v. 18, n. 1, p. 131, doi. 10.1080/15476286.2020.1804697

By:

Wang, Yan-Jie;
Yang, Bing;
Lai, Qiao;
Shi, Jun-Fang;
Peng, Jiang-Yun;
Zhang, Yin;
Hu, Kai-Shun;
Li, Ya-Qing;
Peng, Jing-Wen;
Yang, Zhi-Zhi;
Li, Yao-Ting;
Pan, Yue;
Koeffler, H. Phillip;
Liao, Jian-You;
Yin, Dong

Publication type:

Article

C/EBP∊ mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 9, p. 3316, doi. 10.1172/JCI62070

By:

Kyme, Pierre;
Thoennissen, Nils H.;
Ching Wen Tseng;
Thoennissen, Gabriela B.;
Wolf, Andrea J.;
Shimada, Kenichi;
Krug, Utz O.;
Lee, Kunik;
Müller-Tidow, Carsten;
Berdel, Wolfgang E.;
Hardy, W. David;
Gombart, Adrian F.;
Koeffler, H. Phillip;
Liu, George Y.

Publication type:

Article

Downregulation of 14-3-3sin ovary, prostate and endometrial carcinomas is associated with CpG island methylation.

Published in:

Modern Pathology, 2005, v. 18, n. 3, p. 340, doi. 10.1038/modpathol.3800240

By:

Mhawech, Paulette;
Benz, Ana;
Cerato, Christelle;
Greloz, Vincent;
Assaly, Mounia;
Desmond, Julian C.;
Koeffler, H Phillip;
Lodygin, Dimitri;
Hermeking, Heiko;
Herrmann, François;
Schwaller, Juerg

Publication type:

Article

Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest.

Published in:

Prostate, 2001, v. 49, n. 4, p. 285, doi. 10.1002/pros.10024

By:

Ikezoe, Takayuki;
Chen, Sophie S.;
Heber, David;
Taguchi, Hirokuni;
Koeffler, H. Phillip

Publication type:

Article

PC-SPES: A unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo.

Published in:

Prostate, 2000, v. 42, n. 3, p. 163, doi. 10.1002/(SICI)1097-0045(20000215)42:3<163::AID-PROS1>3.0.CO;2-W

By:

Kubota, Tetsuya;
Hisatake, Junichi;
Hisatake, Yasuko;
Said, Jonathan W.;
Chen, Sophie S.;
Holden, Stuart;
Taguchi, Hirokuni;
Koeffler, H. Phillip

Publication type:

Article

Novel 20-epi-vitamin D3 analog combined with 9-cis-retinoic acid markedly inhibits colony growth of prostate cancer cells.

Published in:

Prostate, 1999, v. 40, n. 3, p. 141, doi. 10.1002/(SICI)1097-0045(19990801)40:3<141::AID-PROS1>3.0.CO;2-C

By:

Elstner, Elena;
Campbell, Moray J.;
Munker, Reinhold;
Shintaku, Peter;
Binderup, Lise;
Heber, David;
Said, Jonathan;
Koeffler, H. Phillip

Publication type:

Article

HHV-8 (KSHV) does not establish latency in prostate cancer cell lines.

Published in:

Prostate, 1997, v. 33, n. 4, p. 286, doi. 10.1002/(SICI)1097-0045(19971201)33:4<286::AID-PROS10>3.0.CO;2-F

By:

Munker, Reinhold;
Tasaka, Taizo;
Park, Dorothy;
Miller, Carl W.;
Koeffler, H. Phillip

Publication type:

Article

Effects of potent vitamin D3 analogs on clonal proliferation of human prostate cancer cell lines.

Published in:

Prostate, 1997, v. 31, n. 2, p. 77, doi. 10.1002/(SICI)1097-0045(19970501)31:2<77::AID-PROS1>3.0.CO;2-E

By:

de Vos, Sven;
Holden, Stuart;
Heber, David;
Elstner, Elena;
Binderup, Lise;
Uskokovic, Milan;
Rude, Bob;
Chen, Dan Lin;
Le, Jennifer;
Cho, Steve K.;
Koeffler, H. Phillip

Publication type:

Article

Point Mutations of the Mxil Gene are Rare in Prostate Cancers.

Published in:

Prostate, 1996, v. 29, n. 3, p. 191, doi. 10.1002/1097-0045(199609)29:3<191::AID-PROS2990290305>3.0.CO;2-1

By:

Kawamata, Norihiko;
Park, Dorothy;
Wilczynski, Sharon;
Yokota, Jun;
Koeffler, H. Phillip

Publication type:

Article

Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma.

Published in:

International Journal of Oncology, 2017, v. 50, n. 3, p. 863, doi. 10.3892/ijo.2017.3864

By:

JIANJUN XIE;
DECHEN LIN;
LEE, DHONG HYUN TONY;
AKUNOWICZ, JENNIFER;
HANSEN, MARC;
MILLER, CARL;
MASASHI SANADA;
MOTOHIRO KATO;
TADAYUKI AKAGI;
NORIHIKO KAWAMATA;
SEISHI OGAWA;
KOEFFLER, H. PHILLIP

Publication type:

Article

Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0159954

By:

Yan, Haiyan;
Hu, Kaishun;
Wu, Wenjing;
Li, Yu;
Tian, Huan;
Chu, Zhonghua;
Koeffler, H. Phillip;
Yin, Dong

Publication type:

Article

SH2B3 ( LNK) mutations from myeloproliferative neoplasms patients have mild loss of function against wild type JAK2 and JAK2 V617F.

Published in:

British Journal of Haematology, 2013, v. 161, n. 6, p. 811, doi. 10.1111/bjh.12327

By:

Koren‐Michowitz, Maya;
Gery, Sigal;
Tabayashi, Takayuki;
Lin, Dechen;
Alvarez, Rocio;
Nagler, Arnon;
Koeffler, H. Phillip

Publication type:

Article

Loss of H19 imprinting in adult T-cell leukaemia/lymphoma.

Published in:

2007

By:

Takeuchi, Seisho;
Hofmann, Wolf-Karsten;
Tsukasaki, Kunihiro;
Takeuchi, Naoko;
Ikezoe, Takayuki;
Matsushita, Masahide;
Uehara, Yoshio;
Koeffler, H. Phillip

Publication type:

Letter

The synthetic furanonaphthoquinone induces growth arrest, apoptosis and differentiation in a variety of leukaemias and multiple myeloma cells.

Published in:

British Journal of Haematology, 2005, v. 131, n. 4, p. 520, doi. 10.1111/j.1365-2141.2005.05803.x

By:

Desmond, Julian C.;
Kawabata, Hiroshi;
Mueller-Tidow, Carsten;
Simamura, Eriko;
Heber, David;
Hirai, Kei-Ichi;
Koeffler, H. Phillip

Publication type:

Article

Analyses for binding of the transferrin family of proteins to the transferrin receptor 2.

Published in:

British Journal of Haematology, 2004, v. 127, n. 4, p. 464, doi. 10.1111/j.1365-2141.2004.05224.x

By:

Kawabata, Hiroshi;
Tong, Xiangjun;
Kawanami, Takafumi;
Wano, Yuji;
Hirose, Yuko;
Sugai, Susumu;
Phillip Koeffler, H.

Publication type:

Article

research paper Elevated levels of transferrin receptor 2 mRNA, not transferrin receptor 1 mRNA, are associated with increased survival in acute myeloid leukaemia.

Published in:

British Journal of Haematology, 2004, v. 125, n. 1, p. 42, doi. 10.1111/j.1365-2141.2004.04866.x

By:

Nakamaki, Tsuyoshi;
Kawabata, Hiroshi;
Saito, Bungo;
Matsunawa, Manabu;
Suzuki, Junko;
Adachi, Daisuke;
Tomayasu, Shigeru;
Koeffler, H. Phillip

Publication type:

Article

Progression of myelodysplastic syndrome: allelic loss on chromosomal arm 1p.

Published in:

British Journal of Haematology, 2003, v. 122, n. 2, p. 226, doi. 10.1046/j.1365-2141.2003.04434.x

By:

Mori, Naoki;
Morosetti, Roberta;
Mizoguchi, Hideaki;
Koeffler, H. Phillip

Publication type:

Article

Genetic polymorphisms in the tumour necrosis factor locus in childhood acute lymphoblastic leukaemia.

Published in:

British Journal of Haematology, 2002, v. 119, n. 4, p. 985, doi. 10.1046/j.1365-2141.2002.03964.x

By:

Takeuchi, Seisho;
Takeuchi, Naoko;
Tsukasaki, Kunihiro;
Bartram, Claus R.;
Zimmermann, Martin;
Schrappe, Martin;
Taguchi, Hirokuni;
Koeffler, H. Phillip

Publication type:

Article