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A peptide of the N terminus of GRK5 attenuates pressure-overload hypertrophy and heart failure.
- Published in:
- Science Signaling, 2021, v. 14, n. 676, p. 1, doi. 10.1126/scisignal.abb5968
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- Publication type:
- Article
Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.
- Published in:
- Science Signaling, 2018, v. 11, n. 560, p. 1, doi. 10.1126/scisignal.aau0144
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- Publication type:
- Article
A peptide of the RGS domain of GRK2 binds and inhibits Gα<sub>q</sub> to suppress pathological cardiac hypertrophy and dysfunction.
- Published in:
- Science Signaling, 2016, v. 9, n. 420, p. 1, doi. 10.1126/scisignal.aae0549
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- Publication type:
- Article
G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.
- Published in:
- PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0182110
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- Publication type:
- Article
TNF-α induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 10, p. 1564, doi. 10.1038/jcbfm.2013.109
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- Publication type:
- Article
Biology of intracranial aneurysms: role of inflammation.
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- Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 9, p. 1659, doi. 10.1038/jcbfm.2012.84
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- Publication type:
- Article
Cardiac-Specific Disruption of Bin1 in Mice Enables a Model of Stress- and Age-Associated Dilated Cardiomyopathy.
- Published in:
- Journal of Cellular Biochemistry, 2015, v. 116, n. 11, p. 2541, doi. 10.1002/jcb.25198
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- Publication type:
- Article
S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 8, p. 1320, doi. 10.1038/mt.2015.93
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- Publication type:
- Article
Cardiac Progenitor Cells Engineered With βARKct Have Enhanced β-Adrenergic Tolerance.
- Published in:
- Molecular Therapy, 2014, v. 22, n. 1, p. 178, doi. 10.1038/mt.2013.200
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- Publication type:
- Article
Modulation of Adrenal Catecholamine Secretion by In Vivo Gene Transfer and Manipulation of G Protein–coupled Receptor Kinase-2 Activity.
- Published in:
- Molecular Therapy, 2008, v. 16, n. 2, p. 302, doi. 10.1038/sj.mt.6300371
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- Publication type:
- Article
S100A1 Gene Therapy Preserves in Vivo Cardiac Function after Myocardial Infarction
- Published in:
- Molecular Therapy, 2005, v. 12, n. 6, p. 1120, doi. 10.1016/j.ymthe.2005.08.002
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- Publication type:
- Article
Prior Exercise Improves Age-Dependent Vascular Endothelial Growth Factor Downregulation and Angiogenesis Responses to Hind-Limb Ischemia in Old Rats.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 5, p. 471, doi. 10.1093/gerona/62.5.471
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- Publication type:
- Article
Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism.
- Published in:
- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00030
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- Publication type:
- Article
Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.
- Published in:
- CTS: Clinical & Translational Science, 2015, v. 8, n. 4, p. 305, doi. 10.1111/cts.12331
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- Publication type:
- Article
Advancing the Research Mission in an Academic Department: The Creation of a Center for Translational Medicine.
- Published in:
- CTS: Clinical & Translational Science, 2010, v. 3, n. 4, p. 178, doi. 10.1111/j.1752-8062.2010.00206.x
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- Publication type:
- Article
Comparative Cardiac Gene Delivery of Adeno-Associated Virus Serotypes 1–9 reveals that AAV6 Mediates the Most Efficient Transduction in Mouse Heart.
- Published in:
- CTS: Clinical & Translational Science, 2010, v. 3, n. 3, p. 81, doi. 10.1111/j.1752-8062.2010.00190.x
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- Publication type:
- Article
Dynamic Changes in Lymphocyte GRK2 Levels in Cardiac Transplant Patients: A Biomarker for Left Ventricular Function.
- Published in:
- CTS: Clinical & Translational Science, 2010, v. 3, n. 1, p. 14, doi. 10.1111/j.1752-8062.2010.00176.x
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- Publication type:
- Article
Negative Regulation of VEGF Signaling in Human Coronary Artery Endothelial Cells by G Protein-Coupled Receptor Kinase 5.
- Published in:
- CTS: Clinical & Translational Science, 2009, v. 2, n. 1, p. 57, doi. 10.1111/j.1752-8062.2008.00058.x
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- Publication type:
- Article
Cardiac-Restricted Overexpression of the A<sub>2A</sub>-Adenosine Receptor in FVB Mice Transiently Increases Contractile Performance and Rescues the Heart Failure Phenotype in Mice Overexpressing the A<sub>1</sub>-Adenosine Receptor.
- Published in:
- CTS: Clinical & Translational Science, 2008, v. 1, n. 2, p. 126, doi. 10.1111/j.1752-8062.2008.00027.x
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- Publication type:
- Article
BMP-2 and FGF-2 Synergistically Facilitate Adoption of a Cardiac Phenotype in Somatic Bone Marrow c-kit+/Sca-1+ Stem Cells.
- Published in:
- CTS: Clinical & Translational Science, 2008, v. 1, n. 2, p. 116, doi. 10.1111/j.1752-8062.2008.00034.x
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- Publication type:
- Article
Simultaneous Administration of Insulin-Like Growth Factor-1 and Darbepoetin Alfa Protects the Rat Myocardium Against Myocardial Infarction and Enhances Angiogenesis.
- Published in:
- CTS: Clinical & Translational Science, 2008, v. 1, n. 1, p. 13, doi. 10.1111/j.1752-8062.2008.00008.x
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- Publication type:
- Article
Epidermal growth factor receptor-dependent maintenance of cardiac contractility.
- Published in:
- Cardiovascular Research, 2022, v. 118, n. 5, p. 1276, doi. 10.1093/cvr/cvab149
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- Publication type:
- Article
G protein-coupled receptor kinase 5 (GRK5) contributes to impaired cardiac function and immune cell recruitment in post-ischemic heart failure.
- Published in:
- Cardiovascular Research, 2022, v. 118, n. 1, p. 169, doi. 10.1093/cvr/cvab044
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- Publication type:
- Article
Overexpression of wild‐type Gαi‐2 suppresses β‐adrenergic signaling in cardiac myocytes.
- Published in:
- FASEB Journal, 2003, v. 17, n. 3, p. 1, doi. 10.1096/fj.02-0660fje
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- Publication type:
- Article
In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 5, p. 1211, doi. 10.3390/cells10051211
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- Publication type:
- Article
Identification and Comparison of Hyperglycemia-Induced Extracellular Vesicle Transcriptome in Different Mouse Stem Cells.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 9, p. 2098, doi. 10.3390/cells9092098
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- Publication type:
- Article
Consequence of the tumor-associated conversion to cyclin D1b.
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- EMBO Molecular Medicine, 2015, v. 7, n. 5, p. 628, doi. 10.15252/emmm.201404242
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- Publication type:
- Article
Adding another GRK to the fire of heart failure.
- Published in:
- 2021
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- Publication type:
- Editorial
Vasopressin type 1A receptor deletion enhances cardiac contractility, β-adrenergic receptor sensitivity and acute cardiac injury-induced dysfunction.
- Published in:
- Clinical Science, 2016, v. 130, n. 22, p. 2017, doi. 10.1042/CS20160363
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- Publication type:
- Article
Alveolar Epithelial β<sub>2</sub>-Adrenergic Receptors.
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- American Journal of Respiratory & Critical Care Medicine, 2004, v. 170, n. 12, p. 1270, doi. 10.1164/rccm.200404-470CP
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- Publication type:
- Article
Urotensin II promotes vagal-mediated bradycardia by activating cardiac-projecting parasympathetic neurons of nucleus ambiguus.
- Published in:
- Journal of Neurochemistry, 2014, v. 129, n. 4, p. 628, doi. 10.1111/jnc.12679
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- Publication type:
- Article
Nesfatin-1 activates cardiac vagal neurons of nucleus ambiguus and elicits bradycardia in conscious rats.
- Published in:
- Journal of Neurochemistry, 2013, v. 126, n. 6, p. 739, doi. 10.1111/jnc.12355
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- Publication type:
- Article
Transgenic Mice Targeting the Heart Unveil G Protein-Coupled Receptor Kinases as Therapeutic Targets.
- Published in:
- Assay & Drug Development Technologies, 2003, v. 1, n. 2, p. 347
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- Publication type:
- Article
Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a G<sub>i</sub> Protein/ROCK/PKD-Sensitive Manner.
- Published in:
- Cardiovascular Drugs & Therapy, 2023, v. 37, n. 2, p. 245, doi. 10.1007/s10557-021-07299-4
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- Publication type:
- Article
Calcium channel function and regulation in β<sub>1</sub>- and β<sub>2</sub>-adrenoceptor transgenic mice.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 369, n. 5, p. 490, doi. 10.1007/s00210-004-0928-3
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- Publication type:
- Article
GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion.
- Published in:
- Journal of Molecular Medicine, 2023, v. 101, n. 11, p. 1379, doi. 10.1007/s00109-023-02373-w
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- Publication type:
- Article
Effects of myocardial ischemia/reperfusion injury on plasma metabolomic profile during aging.
- Published in:
- Aging Cell, 2021, v. 20, n. 1, p. 1, doi. 10.1111/acel.13284
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- Publication type:
- Article
Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice.
- Published in:
- 2019
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- Publication type:
- journal article
Convergence of G Protein-Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury.
- Published in:
- Science Signaling, 2013, v. 6, n. 299, p. 1, doi. 10.1126/scisignal.2004225
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- Publication type:
- Article
Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System.
- Published in:
- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00556
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- Publication type:
- Article
MAP Kinase Phosphatase-5 Deficiency Protects Against Pressure Overload-Induced Cardiac Fibrosis.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.790511
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- Publication type:
- Article
Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition.
- Published in:
- Theranostics, 2022, v. 12, n. 9, p. 4415, doi. 10.7150/thno.70821
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- Publication type:
- Article
GRK2 blockade with βARKct is essential for cardiac β<sub>2</sub>-adrenergic receptor signaling towards increased contractility.
- Published in:
- Cell Communication & Signaling, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1478-811X-11-64
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- Publication type:
- Article
Acute ischemic cardiac dysfunction is attenuated via gene transfer of a peptide inhibitor of the β-adrenergic receptor kinase (βARK1).
- Published in:
- Journal of Gene Medicine, 2005, v. 7, n. 9, p. 1172, doi. 10.1002/jgm.770
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- Publication type:
- Article
Catheter-mediated subselective intracoronary gene delivery to the rabbit heart: introduction of a novel method.
- Published in:
- Journal of Gene Medicine, 2005, v. 7, n. 5, p. 595, doi. 10.1002/jgm.704
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- Publication type:
- Article
S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts.
- Published in:
- Journal of Gene Medicine, 2004, v. 6, n. 4, p. 387, doi. 10.1002/jgm.513
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- Publication type:
- Article
Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor.
- Published in:
- Molecules, 2014, v. 19, n. 10, p. 16937, doi. 10.3390/molecules191016937
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- Publication type:
- Article
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases.
- Published in:
- Nature, 1992, v. 359, n. 6391, p. 147, doi. 10.1038/359147a0
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- Publication type:
- Article
Aldosterone increases cardiac vagal tone via G protein-coupled oestrogen receptor activation.
- Published in:
- Journal of Physiology, 2013, v. 591, n. 17, p. 4223, doi. 10.1113/jphysiol.2013.257204
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- Publication type:
- Article
Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases.
- Published in:
- Nature Communications, 2016, v. 7, n. 3, p. 10877, doi. 10.1038/ncomms10877
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- Publication type:
- Article