Works by Kobayashi, Susumu S.

Results: 20

Clinical Benefit of Tyrosine Kinase Inhibitors in Advanced Lung Cancer with EGFR‐G719A and Other Uncommon EGFR Mutations.

Published in:

Oncologist, 2021, v. 26, n. 4, p. 281, doi. 10.1002/onco.13537

By:

Sehgal, Kartik;
Rangachari, Deepa;
VanderLaan, Paul A.;
Kobayashi, Susumu S.;
Costa, Daniel B.

Publication type:

Article

Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.

Published in:

2020

By:

Takei, Hisashi;
Fukuda, Hirofumi;
Pan, Gilbert;
Yamazaki, Hiroyuki;
Matsumoto, Tadahiko;
Kazuma, Yasuhiro;
Fujii, Masanori;
Nakayama, Sohei;
Kobayashi, Ikei S.;
Shindo, Keisuke;
Yamashita, Riu;
Shirakawa, Kotaro;
Takaori-Kondo, Akifumi;
Kobayashi, Susumu S.

Publication type:

journal article

Targeting transcription factors in acute myeloid leukemia.

Published in:

2019

By:

Takei, Hisashi;
Kobayashi, Susumu S.

Publication type:

journal article

TAS2940, a novel brain‐penetrable pan‐ERBB inhibitor, for tumors with HER2 and EGFR aberrations.

Published in:

Cancer Science, 2023, v. 114, n. 2, p. 654, doi. 10.1111/cas.15617

By:

Oguchi, Kei;
Araki, Hikari;
Tsuji, Shingo;
Nakamura, Masayuki;
Miura, Akihiro;
Funabashi, Kaoru;
Osada, Akiko;
Tanaka, Sakiho;
Suzuki, Takamasa;
Kobayashi, Susumu S.;
Mizuarai, Shinji

Publication type:

Article

Suppression of multiple anti‐apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms.

Published in:

Cancer Science, 2022, v. 113, n. 2, p. 597, doi. 10.1111/cas.15210

By:

Takei, Hisashi;
Coelho‐Silva, Juan Luiz;
Tavares Leal, Cristina;
Queiroz Arantes Rocha, Adriana;
Mantello Bianco, Thiago;
Welner, Robert S.;
Mishima, Yuta;
Kobayashi, Ikei S.;
Mullally, Ann;
Lima, Keli;
Machado‐Neto, João Agostinho;
Kobayashi, Susumu S.;
Lobo de Figueiredo‐Pontes, Lorena

Publication type:

Article

EGFR-D770>GY and Other Rare EGFR Exon 20 Insertion Mutations with a G770 Equivalence Are Sensitive to Dacomitinib or Afatinib and Responsive to EGFR Exon 20 Insertion Mutant-Active Inhibitors in Preclinical Models and Clinical Scenarios.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3561, doi. 10.3390/cells10123561

By:

Kobayashi, Ikei S.;
Viray, Hollis;
Rangachari, Deepa;
Kobayashi, Susumu S.;
Costa, Daniel B.

Publication type:

Article

NAD Modulates DNA Methylation and Cell Differentiation.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2986, doi. 10.3390/cells10112986

By:

Ummarino, Simone;
Hausman, Clinton;
Gaggi, Giulia;
Rinaldi, Lucrezia;
Bassal, Mahmoud A.;
Zhang, Yanzhou;
Seelam, Andy Joe;
Kobayashi, Ikei S.;
Borchiellini, Marta;
Ebralidze, Alexander K.;
Ghinassi, Barbara;
Trinh, Bon Q.;
Kobayashi, Susumu S.;
Di Ruscio, Annalisa

Publication type:

Article

NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-21419-6

By:

de Miranda, Lívia Bassani Lins;
Lima, Keli;
Coelho-Silva, Juan Luiz;
Traina, Fabiola;
Kobayashi, Susumu S.;
Machado-Neto, João Agostinho

Publication type:

Article

Detection of Crizotinib-Sensitive Lung Adenocarcinomas With MET, ALK, and ROS1 Genomic Alterations via Comprehensive Genomic Profiling.

Published in:

2015

By:

Le, Xiuning;
Freed, Jason A;
VanderLaan, Paul A;
Huberman, Mark S;
Rangachari, Deepa;
Jorge, Susan E;
Lucena-Araujo, Antonio R;
Kobayashi, Susumu S;
Balasubramanian, Sohail;
He, Jie;
Chudnovsky, Yakov;
Miller, Vincent A;
Ali, Siraj M;
Costa, Daniel B

Publication type:

journal article

HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs.

Published in:

Thoracic Cancer, 2021, v. 12, n. 5, p. 631, doi. 10.1111/1759-7714.13839

By:

Watanabe, Sho;
Goto, Yasushi;
Yasuda, Hiroyuki;
Kohno, Takashi;
Motoi, Noriko;
Ohe, Yuichiro;
Nishikawa, Hiroyoshi;
Kobayashi, Susumu S.;
Kuwano, Kazuyoshi;
Togashi, Yosuke

Publication type:

Article

An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1.

Published in:

British Journal of Cancer, 2023, v. 128, n. 9, p. 1647, doi. 10.1038/s41416-023-02196-z

By:

Aftab, Fareesa;
Rodriguez-Fuguet, Alice;
Silva, Luis;
Kobayashi, Ikei S.;
Sun, Jiao;
Politi, Katerina;
Levantini, Elena;
Zhang, Wei;
Kobayashi, Susumu S.;
Zhang, Wen Cai

Publication type:

Article

LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06116-6

By:

Mori, Shunta;
Izumi, Hiroki;
Araki, Mitsugu;
Liu, Jie;
Tanaka, Yu;
Kagawa, Yosuke;
Sagae, Yukari;
Ma, Biao;
Isaka, Yuta;
Sasakura, Yoko;
Kumagai, Shogo;
Sakae, Yuta;
Tanaka, Kosuke;
Shibata, Yuji;
Udagawa, Hibiki;
Matsumoto, Shingo;
Yoh, Kiyotaka;
Okuno, Yasushi;
Goto, Koichi;
Kobayashi, Susumu S.

Publication type:

Article

A Real-World Study of Patient Characteristics and Clinical Outcomes in EGFR Mutated Lung Cancer Treated with First-Line Osimertinib: Expanding the FLAURA Trial Results into Routine Clinical Practice.

Published in:

Cancers, 2024, v. 16, n. 6, p. 1079, doi. 10.3390/cancers16061079

By:

Viray, Hollis;
Piper-Vallillo, Andrew J.;
Widick, Page;
Academia, Emmeline;
Shea, Meghan;
Rangachari, Deepa;
VanderLaan, Paul A.;
Kobayashi, Susumu S.;
Costa, Daniel B.

Publication type:

Article

Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78646-y

By:

Fujimoto, Yumi;
Morita, Tomoko Yamamori;
Ohashi, Akihiro;
Haeno, Hiroshi;
Hakozaki, Yumi;
Fujii, Masanori;
Kashima, Yukie;
Kobayashi, Susumu S.;
Mukohara, Toru

Publication type:

Article

CCAAT/Enhancer Binding Protein β Is Dispensable for Development of Lung Adenocarcinoma.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120647

By:

Cai, Yi;
Hirata, Ayako;
Nakayama, Sohei;
VanderLaan, Paul A.;
Levantini, Elena;
Yamamoto, Mihoko;
Hirai, Hideyo;
Wong, Kwok-Kin;
Costa, Daniel B.;
Watanabe, Hideo;
Kobayashi, Susumu S.

Publication type:

Article

TIP60 is required for tumorigenesis in non‐small cell lung cancer.

Published in:

Cancer Science, 2023, v. 114, n. 6, p. 2400, doi. 10.1111/cas.15785

By:

Shibahara, Daisuke;
Akanuma, Naoki;
Kobayashi, Ikei S.;
Heo, Eunyoung;
Ando, Mariko;
Fujii, Masanori;
Jiang, Feng;
Prin, P. Nicholas;
Pan, Gilbert;
Wong, Kwok‐Kin;
Costa, Daniel B.;
Bararia, Deepak;
Tenen, Daniel G.;
Watanabe, Hideo;
Kobayashi, Susumu S.

Publication type:

Article

Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα.

Published in:

Molecules, 2018, v. 23, n. 8, p. 1938, doi. 10.3390/molecules23081938

By:

Sanda, Takaomi;
Sridhar, Radhakrishnan;
Hui, Liu Bee;
Tenen, Daniel G.;
Kobayashi, Ikei S.;
Takei, Hisashi;
Kobayashi, Susumu S.;
Syed, Riyaz;
Kamal, Ahmed

Publication type:

Article

Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1137966

By:

Qian Yu;
Kobayashi, Susumu S.;
Hiroshi Haeno

Publication type:

Article

Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.768592

By:

de Oliveira Costa, Amanda Fernandes;
Marani, Leticia Olops;
Bianco, Thiago Mantello;
Arantes, Adriana Queiroz;
Lopes, Izabela Aparecida;
Pereira-Martins, Diego Antonio;
Palma, Leonardo Carvalho;
Scheucher, Priscila Santos;
dos Santos Schiavinato, Josiane Lilian;
Binelli, Larissa Sarri;
Araújo Silva, Cleide;
Kobayashi, Susumu S.;
Agostinho Machado-Neto, João;
Magalhães Rego, Eduardo;
Welner, Robert Samuel;
Lobo de Figueiredo-Pontes, Lorena

Publication type:

Article

Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer.

Published in:

Cell Death & Disease, 2024, v. 15, n. 8, p. 1, doi. 10.1038/s41419-024-06940-y

By:

Izumi, Motohiro;
Fujii, Masanori;
Kobayashi, Ikei S.;
Ho, Vivian;
Kashima, Yukie;
Udagawa, Hibiki;
Costa, Daniel B.;
Kobayashi, Susumu S.

Publication type:

Article