Works by Knoblich, Juergen A

Results: 35

Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

Published in:

Genome Biology, 2013, v. 14, n. 11, p. 1, doi. 10.1186/gb-2013-14-11-r133

By:

Jüschke, Christoph;
Dohnal, Ilse;
Pichler, Peter;
Harzer, Heike;
Swart, Remco;
Ammerer, Gustav;
Mechtler, Karl;
Knoblich, Juergen A.

Publication type:

Article

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.

Published in:

EMBO Journal, 2013, v. 32, n. 11, p. 1598, doi. 10.1038/emboj.2013.93

By:

Sparmann, Anke;
Xie, Yunli;
Verhoeven, Els;
Vermeulen, Michiel;
Lancini, Cesare;
Gargiulo, Gaetano;
Hulsman, Danielle;
Mann, Matthias;
Knoblich, Juergen A;
van Lohuizen, Maarten

Publication type:

Article

Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN.

Published in:

Nature Cell Biology, 2014, v. 16, n. 8, p. 758, doi. 10.1038/ncb3001

By:

Williams, Scott E.;
Ratliff, Lyndsay A.;
Postiglione, Maria Pia;
Knoblich, Juergen A.;
Fuchs, Elaine

Publication type:

Article

The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements.

Published in:

Nature Cell Biology, 2011, v. 13, n. 9, p. 1029, doi. 10.1038/ncb2306

By:

Richter, Constance;
Oktaba, Katarzyna;
Steinmann, Jonas;
Müller, Jürg;
Knoblich, Juergen A.

Publication type:

Article

Wicked views on stem cell news.

Published in:

Nature Cell Biology, 2009, v. 11, n. 6, p. 678, doi. 10.1038/ncb0609-678

By:

Neum&üller, Ralph A.;
Knoblich, Juergen A.

Publication type:

Article

Pins for spines.

Published in:

Nature Cell Biology, 2005, v. 7, n. 12, p. 1057, doi. 10.1038/ncb1205-1057

By:

Knoblich, Juergen A.

Publication type:

Article

Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.

Published in:

Nature Cell Biology, 2005, v. 7, n. 11, p. 1099, doi. 10.1038/ncb1318

By:

Hampoelz, Bernhard;
Hoeller, Oliver;
Bowman, Sarah K.;
Dunican, Dara;
Knoblich, Juergen A.

Publication type:

Article

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.

Published in:

Nature Cell Biology, 2001, v. 3, n. 1, p. 43, doi. 10.1038/35050550

By:

Petronczki, Mark;
Knoblich, Juergen A.

Publication type:

Article

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets.

Published in:

EMBO Journal, 2022, v. 41, n. 17, p. 1, doi. 10.15252/embj.2022111118

By:

Vértesy, Ábel;
Eichmüller, Oliver L;
Naas, Julia;
Novatchkova, Maria;
Esk, Christopher;
Balmaña, Meritxell;
Ladstaetter, Sabrina;
Bock, Christoph;
von Haeseler, Arndt;
Knoblich, Juergen A

Publication type:

Article

Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration.

Published in:

EMBO Journal, 2021, v. 40, n. 23, p. 1, doi. 10.15252/embj.2021108714

By:

Bajaj, Sunanjay;
Bagley, Joshua A;
Sommer, Christoph;
Vertesy, Abel;
Nagumo Wong, Sakurako;
Krenn, Veronica;
Lévi‐Strauss, Julie;
Knoblich, Juergen A

Publication type:

Article

Self-organized developmental patterning and differentiation in cerebral organoids.

Published in:

EMBO Journal, 2017, v. 36, n. 10, p. 1316, doi. 10.15252/embj.201694700

By:

Renner, Magdalena;
Lancaster, Madeline A;
Bian, Shan;
Choi, Heejin;
Ku, Taeyun;
Peer, Angela;
Chung, Kwanghun;
Knoblich, Juergen A

Publication type:

Article

Micro RNA-34/449 controls mitotic spindle orientation during mammalian cortex development.

Published in:

EMBO Journal, 2016, v. 35, n. 22, p. 2386, doi. 10.15252/embj.201694056

By:

Fededa, Juan Pablo;
Esk, Christopher;
Mierzwa, Beata;
Stanyte, Rugile;
Yuan, Shuiqiao;
Zheng, Huili;
Ebnet, Klaus;
Yan, Wei;
Knoblich, Juergen A;
Gerlich, Daniel W

Publication type:

Article

Cerebral organoids model human brain development and microcephaly.

Published in:

Nature, 2013, v. 501, n. 7467, p. 373, doi. 10.1038/nature12517

By:

Lancaster, Madeline A.;
Renner, Magdalena;
Martin, Carol-Anne;
Wenzel, Daniel;
Bicknell, Louise S.;
Hurles, Matthew E.;
Homfray, Tessa;
Penninger, Josef M.;
Jackson, Andrew P.;
Knoblich, Juergen A.

Publication type:

Article

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.

Published in:

Nature, 2009, v. 458, n. 7241, p. 987, doi. 10.1038/nature07936

By:

Mummery-Widmer, Jennifer L.;
Yamazaki, Masakazu;
Stoeger, Thomas;
Novatchkova, Maria;
Bhalerao, Sheetal;
Chen, Doris;
Dietzl, Georg;
Dickson, Barry J.;
Knoblich, Juergen A.

Publication type:

Article

The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda.

Published in:

EMBO Reports, 2018, v. 19, n. 1, p. 102, doi. 10.15252/embr.201744188

By:

Reichardt, Ilka;
Bonnay, François;
Steinmann, Victoria;
Loedige, Inga;
Burkard, Thomas R.;
Meister, Gunter;
Knoblich, Juergen A.

Publication type:

Article

Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.

Published in:

EMBO Reports, 2005, v. 6, n. 9, p. 836, doi. 10.1038/sj.embor.7400500

By:

Hutterer, Andrea;
Knoblich, Juergen A

Publication type:

Article

Asymmetric cell division: recent developments and their implications for tumour biology.

Published in:

Nature Reviews Molecular Cell Biology, 2010, v. 11, n. 12, p. 849, doi. 10.1038/nrm3010

By:

Knoblich, Juergen A.

Publication type:

Article

CELL DIVISION: ASYMMETRIC CELL DIVISION DURING ANIMAL DEVELOPMENT.

Published in:

Nature Reviews Molecular Cell Biology, 2001, v. 2, n. 1, p. 11, doi. 10.1038/35048085

By:

Knoblich, Juergen A.

Publication type:

Article

The TRIM-NHL Protein Brat Promotes Axon Maintenance by Repressing src64B Expression.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 41, p. 13855, doi. 10.1523/JNEUROSCI.3285-13.2014

By:

Marchetti, Giovanni;
Reichardt, Ilka;
Knoblich, Juergen A.;
Besse, Florence

Publication type:

Article

Generation of cerebral organoids from human pluripotent stem cells.

Published in:

Nature Protocols, 2014, v. 9, n. 10, p. 2329, doi. 10.1038/nprot.2014.158

By:

Lancaster, Madeline A;
Knoblich, Juergen A

Publication type:

Article

FACS purification of Drosophila larval neuroblasts for next-generation sequencing.

Published in:

Nature Protocols, 2013, v. 8, n. 6, p. 1088, doi. 10.1038/nprot.2013.062

By:

Harzer, Heike;
Berger, Christian;
Conder, Ryan;
Schmauss, Gerald;
Knoblich, Juergen A.

Publication type:

Article

Identification of transcription factor binding sites from ChIP-seq data at high resolution.

Published in:

Bioinformatics, 2013, v. 29, n. 21, p. 2705, doi. 10.1093/bioinformatics/btt470

By:

Bardet, Anaïs F.;
Steinmann, Jonas;
Bafna, Sangeeta;
Knoblich, Juergen A.;
Zeitlinger, Julia;
Stark, Alexander

Publication type:

Article

The Organoid Cell Atlas.

Published in:

2021

By:

Bock, Christoph;
Boutros, Michael;
Camp, J. Gray;
Clarke, Laura;
Clevers, Hans;
Knoblich, Juergen A.;
Liberali, Prisca;
Regev, Aviv;
Rios, Anne C.;
Stegle, Oliver;
Stunnenberg, Hendrik G.;
Teichmann, Sarah A.;
Treutlein, Barbara;
Vries, Robert G. J.

Publication type:

Letter

Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids.

Published in:

Nature Biotechnology, 2018, v. 36, n. 10, p. 1016, doi. 10.1038/nbt1018-1016a

By:

Lancaster, Madeline A;
Corsini, Nina S;
Wolfinger, Simone;
Gustafson, E Hilary;
Phillips, Alex W;
Burkard, Thomas R;
Otani, Tomoki;
Livesey, Frederick J;
Knoblich, Juergen A

Publication type:

Article

Guided self-organization and cortical plate formation in human brain organoids.

Published in:

Nature Biotechnology, 2017, v. 35, n. 7, p. 659, doi. 10.1038/nbt.3906

By:

Lancaster, Madeline A;
Corsini, Nina S;
Wolfinger, Simone;
Gustafson, E Hilary;
Phillips, Alex W;
Burkard, Thomas R;
Otani, Tomoki;
Livesey, Frederick J;
Knoblich, Juergen A

Publication type:

Article

Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop.

Published in:

Journal of Cell Biology, 2018, v. 217, n. 9, p. 3285, doi. 10.1083/jcb.201711167

By:

Wissel, Sebastian;
Harzer, Heike;
Bonnay, François;
Burkard, Thomas R.;
Neumüller, Ralph A.;
Knoblich, Juergen A.

Publication type:

Article

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.

Published in:

Nature, 2008, v. 454, n. 7201, p. 241, doi. 10.1038/nature07014

By:

Neumüller, Ralph A.;
Betschinger, Joerg;
Fischer, Anja;
Bushati, Natascha;
Poernbacher, Ingrid;
Mechtler, Karl;
Cohen, Stephen M.;
Knoblich, Juergen A.

Publication type:

Article

Neurobiology: Getting axons going.

Published in:

Nature, 2005, v. 436, n. 7051, p. 632, doi. 10.1038/436632a

By:

Knoblich, Juergen A.

Publication type:

Article

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

Published in:

Nature, 2003, v. 422, n. 6929, p. 326, doi. 10.1038/nature01486

By:

Betschinger, Jorg;
Mechtler, Karl;
Knoblich, Juergen A.

Publication type:

Article

A whole‐genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors.

Published in:

EMBO Molecular Medicine, 2023, v. 15, n. 3, p. 1, doi. 10.15252/emmm.202216959

By:

Taubenschmid‐Stowers, Jasmin;
Orthofer, Michael;
Laemmerer, Anna;
Krauditsch, Christian;
Rózsová, Marianna;
Studer, Christian;
Lötsch, Daniela;
Gojo, Johannes;
Gabler, Lisa;
Dyczynski, Matheus;
Efferth, Thomas;
Hagelkruys, Astrid;
Widhalm, Georg;
Peyrl, Andreas;
Spiegl‐Kreinecker, Sabine;
Hoepfner, Dominic;
Bian, Shan;
Berger, Walter;
Knoblich, Juergen A;
Elling, Ulrich

Publication type:

Article

A Regulatory Transcriptional Loop Controls Proliferation and Differentiation in Drosophila Neural Stem Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097034

By:

Yasugi, Tetsuo;
Fischer, Anja;
Jiang, Yanrui;
Reichert, Heinrich;
Knoblich, Juergen A.

Publication type:

Article

Long-Term Live Cell Imaging and Automated 4D Analysis of Drosophila Neuroblast Lineages.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079588

By:

Homem, Catarina C. F.;
Reichardt, Ilka;
Berger, Christian;
Lendl, Thomas;
Knoblich, Juergen A.

Publication type:

Article

The orientation of asymmetric cell divisions directs lineage decisions in the mouse neocortex

Published in:

2012

By:

Postiglione, Maria Pia;
Xie, Yunli;
Jüschke, Christoph;
Haas, Gerald A.;
Charalambous, Christoforos;
Knoblich, Juergen A.

Publication type:

Abstract

Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering.

Published in:

Advanced Materials, 2023, v. 35, n. 41, p. 1, doi. 10.1002/adma.202300305

By:

Ritzau‐Reid, Kaja I.;
Callens, Sebastien J. P.;
Xie, Ruoxiao;
Cihova, Martina;
Reumann, Daniel;
Grigsby, Christopher L.;
Prados‐Martin, Lino;
Wang, Richard;
Moore, Axel C.;
Armstrong, James P. K.;
Knoblich, Juergen A.;
Stevens, Molly M.

Publication type:

Article

Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering.

Published in:

Advanced Materials, 2023, v. 35, n. 41, p. 1, doi. 10.1002/adma.202300305

By:

Ritzau‐Reid, Kaja I.;
Callens, Sebastien J. P.;
Xie, Ruoxiao;
Cihova, Martina;
Reumann, Daniel;
Grigsby, Christopher L.;
Prados‐Martin, Lino;
Wang, Richard;
Moore, Axel C.;
Armstrong, James P. K.;
Knoblich, Juergen A.;
Stevens, Molly M.

Publication type:

Article

Works by Knoblich, Juergen A

Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.

Par3-mInsc and Gα<sub>i3</sub> cooperate to promote oriented epidermal cell divisions through LGN.

The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements.

Wicked views on stem cell news.

Pins for spines.

Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets.

Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration.

Self-organized developmental patterning and differentiation in cerebral organoids.

Micro RNA-34/449 controls mitotic spindle orientation during mammalian cortex development.

Cerebral organoids model human brain development and microcephaly.

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.

The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda.

Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.

Asymmetric cell division: recent developments and their implications for tumour biology.

CELL DIVISION: ASYMMETRIC CELL DIVISION DURING ANIMAL DEVELOPMENT.

The TRIM-NHL Protein Brat Promotes Axon Maintenance by Repressing src64B Expression.

Generation of cerebral organoids from human pluripotent stem cells.

FACS purification of Drosophila larval neuroblasts for next-generation sequencing.

Identification of transcription factor binding sites from ChIP-seq data at high resolution.

The Organoid Cell Atlas.

Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids.

Guided self-organization and cortical plate formation in human brain organoids.

Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop.

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.

Neurobiology: Getting axons going.

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

A whole‐genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors.

A Regulatory Transcriptional Loop Controls Proliferation and Differentiation in <i>Drosophila</i> Neural Stem Cells.

Long-Term Live Cell Imaging and Automated 4D Analysis of <i>Drosophila</i> Neuroblast Lineages.

The orientation of asymmetric cell divisions directs lineage decisions in the mouse neocortex

Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering.

Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering.