Works by Knip, M

Results: 179

Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.

Published in:

2000

By:

Paronen J;
Knip M;
Savilahti E;
Virtanen SM;
Ilonen J;
Åkerblom HK;
Vaarala O;
Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group;
Paronen, J;
Knip, M;
Savilahti, E;
Virtanen, S M;
Ilonen, J;
Akerblom, H K;
Vaarala, O

Publication type:

journal article

Severe antibody-mediated human insulin resistance: successful treatment with the insulin analog lispro. A case report.

Published in:

1997

By:

Lahtela JT;
Knip M;
Paul R;
Antonen J;
Salmi J;
Lahtela, J T;
Knip, M;
Paul, R;
Antonen, J;
Salmi, J

Publication type:

journal article

Lack of association of T cell receptor beta-chain constant region polymorphism with insulin-dependent diabetes mellitus in Finland.

Published in:

Clinical & Experimental Immunology, 1990, v. 81, n. 3, p. 396

By:

Reijonen, H.;
Stlvennoinen-Kassinen, S.;
Ilonen, J.;
Knip, M.

Publication type:

Article

Maternal dietary fat and fatty acid intake during lactation and the risk of asthma in the offspring.

Published in:

Acta Paediatrica, 2012, v. 101, n. 8, p. e337, doi. 10.1111/j.1651-2227.2012.02718.x

By:

Lumia, M;
Luukkainen, P;
Kaila, M;
Tapanainen, H;
Takkinen, H-M;
Prasad, M;
Niinistö, S;
Nwaru, B I;
Kenward, M G;
Ilonen, J;
Simell, O;
Knip, M;
Veijola, R;
Virtanen, S M

Publication type:

Article

Feasibility and compliance in a nutritional primary prevention trial in infants at increased risk for type 1 diabetes.

Published in:

Acta Paediatrica, 2011, v. 100, n. 4, p. 557, doi. 10.1111/j.1651-2227.2010.02107.x

By:

Virtanen, S. M.;
Bärlund, S.;
Salonen, M.;
Savilahti, E.;
Reunanen, A.;
Paronen, J.;
Hämäläinen, A.-M.;
Ilonen, J.;
Teramo, K.;
Erkkola, M.;
Ormisson, A.;
Einberg, Ü.;
Riikjärv, M.-A.;
Ludvigsson, J. G.;
Knip, M.;
Åkerblom, H. K.

Publication type:

Article

Validation of a questionnaire on cow's milk allergy: parental reports and physician's diagnosis.

Published in:

2010

By:

Tuokkola J;
Luukkainen P;
Kaila M;
Tapanainen H;
Klaukka T;
Veijola R;
Simell O;
Knip M;
Virtanen SM

Publication type:

Journal Article

Validation of a questionnaire on cow’s milk allergy: parental reports and physician’s diagnosis.

Published in:

Acta Paediatrica, 2010, v. 99, n. 8, p. 1273, doi. 10.1111/j.1651-2227.2010.01772.x

By:

Tuokkola, J.;
Luukkainen, P.;
Kaila, M.;
Tapanainen, H.;
Klaukka, T.;
Veijola, R.;
Simell, O.;
Knip, M.;
Virtanen, S. M.

Publication type:

Article

Antibodies to GAD65 Epitopes at Diagnosis and Over the First 10 years of Clinical Type 1 Diabetes Mellitus.

Published in:

Scandinavian Journal of Immunology, 2004, v. 59, n. 3, p. 334, doi. 10.1111/j.0300-9475.2004.01402.x

By:

Ronkainen, M.S.;
Savola, K.;
Knip, M.

Publication type:

Article

Cytokine Expression in Unstimulated PBMC of Children with Type 1 Diabetes and Subjects Positive for Diabetes-Associated Antibodies.

Published in:

Scandinavian Journal of Immunology, 2001, v. 53, n. 5, p. 510, doi. 10.1046/j.1365-3083.2001.00904.x

By:

Halminen, M.;
Simell, O.;
Knip, M.;
Ilonen, J.

Publication type:

Article

Tumour Necrosis Factor-β Gene RFLP Alleles in Finnish IDDM Haplotypes.

Published in:

Scandinavian Journal of Immunology, 1992, v. 36, n. 6, p. 779

By:

Ilonen, J.;
Merivuori, H.;
Reijonen, H.;
Knip, M.;
Åkerblom, H. K.;
Pociot, F.;
Nerup, J.

Publication type:

Article

Dynamics of Diabetes-Associated Autoantibodies in Young Children with Human Leukocyte Antigen- Conferred Risk of Type 1 Diabetes Recruited from the General Population.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 5, p. 2712, doi. 10.1210/jc.2004-1371

By:

Kukko, M.;
Kimpimäki, T.;
Korhonen, S.;
Kupila, A.;
Simell, S.;
Veijola, R.;
Simell, T.;
Ilonen, J.;
Simell, O.;
Knip, M.

Publication type:

Article

Genetic Modification of Risk Assessment Based on Staging of Preclinical Type 1 Diabetes in Siblings of Affected Children.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 6, p. 2682, doi. 10.1210/jc.2002-020644

By:

MRENA, S.;
SAVOLA, K.;
REIJONEN, H.;
ILONEN, J.;
ÅKERBLOM, H. K.;
KNIP, M.;
KULMALA, P.

Publication type:

Article

Genetic modification of risk assessment based on staging of preclinical type 1 diabetes in siblings of affected children.

Published in:

2003

By:

MRENA, S.;
SAVOLA, K.;
KULMALA, P.;
REIJONEN, H.;
ILONEN, J.;
ÅKERBLOM, H. K.;
KNIP, M

Publication type:

journal article

Natural History of β-Cell Autoimmunity in Young Children with Increased Genetic Susceptibility to Type 1 Diabetes Recruited from the General Population.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 10, p. 4572, doi. 10.1210/jc.2002-020018

By:

KIMPIMÄKI, T.;
KULMALA, P.;
SAVOLA, K.;
KUPILA, A.;
KORHONEN, S.;
SIMELL, T.;
ILONEN, J.;
SIMELL, O.;
KNIP, M.

Publication type:

Article

The first signs of β-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 10, p. 4782, doi. 10.1210/jc.86.10.4782

By:

KIMPIMÄKI, T.;
KUPILA, A.;
HÄMÄLÄINEN, A.-M.;
KUKKO, M.;
KULMALA, P.;
SAVOLA, K.;
SIMELL, T.;
KESKINEN, P.;
ILONEN, J.;
SIMELL, O.;
KNIP, M.

Publication type:

Article

Disease-associated autoantibodies as surrogate markers of type 1 diabetes in young children at increased genetic risk. Childhood Diabetes in Finland Study Group.

Published in:

2000

By:

Kimpimäki, T.;
Kulmala, P.;
Savola, K.;
Vähäsalo, P.;
Reijonen, H.;
Ilonen, J.;
Akerblom, H. K.;
Knip, M.

Publication type:

journal article

Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk.

Published in:

Diabetologia, 2012, v. 55, n. 7, p. 1926, doi. 10.1007/s00125-012-2523-3

By:

Parikka, V.;
Näntö-Salonen, K.;
Saarinen, M.;
Simell, T.;
Ilonen, J.;
Hyöty, H.;
Veijola, R.;
Knip, M.;
Simell, O.

Publication type:

Article

Descriptive epidemiology of type 1 diabetes-is it still in?

Published in:

Diabetologia, 2012, v. 55, n. 5, p. 1227, doi. 10.1007/s00125-012-2522-4

By:

Knip, M.

Publication type:

Article

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

Published in:

Diabetologia, 2011, v. 54, n. 5, p. 1032, doi. 10.1007/s00125-011-2058-z

By:

Forbes, J.;
Söderlund, J.;
Yap, F.;
Knip, M.;
Andrikopoulos, S.;
Ilonen, J.;
Simell, O.;
Veijola, R.;
Sourris, K.;
Coughlan, M.;
Forsblom, C.;
Slattery, R.;
Grey, S.;
Wessman, M.;
Yamamoto, H.;
Bierhaus, A.;
Cooper, M.;
Groop, P.-H.

Publication type:

Article

Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

Published in:

2011

By:

Forbes, J.;
Söderlund, J.;
Yap, F.;
Knip, M.;
Andrikopoulos, S.;
Ilonen, J.;
Simell, O.;
Veijola, R.;
Sourris, K.;
Coughlan, M.;
Forsblom, C.;
Slattery, R;
Grey, S.;
Wessman, M.;
Yamamoto, H.;
Bierhaus, A.;
Cooper, M.;
Groop, P.-H.

Publication type:

Correction Notice

Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment.

Published in:

Diabetologia, 2010, v. 53, n. 12, p. 2487, doi. 10.1007/s00125-010-1878-6

By:

Kordonouri, O.;
Pankowska, E.;
Rami, B.;
Kapellen, T.;
Coutant, R.;
Hartmann, R.;
Lange, K.;
Knip, M.;
Danne, T.

Publication type:

Article

Maternal intake of vitamin D during pregnancy and risk of advanced beta cell autoimmunity and type 1 diabetes in offspring.

Published in:

Diabetologia, 2010, v. 53, n. 8, p. 1599, doi. 10.1007/s00125-010-1734-8

By:

Marjamäki, L.;
Niinistö, S.;
Kenward, M.;
Uusitalo, L.;
Uusitalo, U.;
Ovaskainen, M.-L.;
Kronberg-Kippilä, C.;
Simell, O.;
Veijola, R.;
Ilonen, J.;
Knip, M.;
Virtanen, S.

Publication type:

Article

The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.

Published in:

Diabetologia, 2010, v. 53, n. 1, p. 98, doi. 10.1007/s00125-009-1561-y

By:

Jermendy, A.;
Szatmári, I.;
Laine, A.;
Lukács, K.;
Horváth, K.;
Körner, A.;
Madácsy, L.;
Veijola, R.;
Simell, O.;
Knip, M.;
Ilonen, J.;
Hermann, R.

Publication type:

Article

Analysis of pancreas tissue in a child positive for islet cell antibodies.

Published in:

Diabetologia, 2008, v. 51, n. 10, p. 1796, doi. 10.1007/s00125-008-1107-8

By:

Oikarinen, M.;
Tauriainen, S.;
Honkanen, T.;
Vuori, K.;
Karhunen, P.;
Vasama-Nolvi, C.;
Oikarinen, S.;
Verbeke, C.;
Blair, G.;
Rantala, I.;
Ilonen, J.;
Simell, O.;
Knip, M.;
Hyöty, H.

Publication type:

Article

Serum α- and γ-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.

Published in:

Diabetologia, 2008, v. 51, n. 5, p. 773, doi. 10.1007/s00125-008-0959-2

By:

Uusitalo, L.;
Nevalainen, J.;
Niinistö, S.;
Alfthan, G.;
Sundvall, J.;
Korhonen, T.;
Kenward, M.;
Oja, H.;
Veijola, R.;
Simell, O.;
Ilonen, J.;
Knip, M.;
Virtanen, S.

Publication type:

Article

Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes.

Published in:

Diabetologia, 2008, v. 51, n. 5, p. 769, doi. 10.1007/s00125-008-0945-8

By:

Aarnisalo, J.;
Veijola, R.;
Vainionpää, R.;
Simell, O.;
Knip, M.;
Ilonen, J.

Publication type:

Article

Prediction of type 1 diabetes among siblings of affected children and in the general population.

Published in:

Diabetologia, 2007, v. 50, n. 11, p. 2272, doi. 10.1007/s00125-007-0799-5

By:

Siljander, H.;
Veijola, R.;
Reunanen, A.;
Virtanen, S.;
Åkerblom, H.;
Knip, M.

Publication type:

Article

Age at introduction of new foods and advanced beta cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes.

Published in:

Diabetologia, 2006, v. 49, n. 7, p. 1512, doi. 10.1007/s00125-006-0236-1

By:

Virtanen, S. M.;
Kenward, M. G.;
Erkkola, M.;
Kautiainen, S.;
Kronberg-Kippilä, C.;
Hakulinen, T.;
Ahonen, S.;
Uusitalo, L.;
Niinistö, S.;
Veijola, R.;
Simell, O.;
Ilonen, J.;
Knip, M.

Publication type:

Article

Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes.

Published in:

Diabetologia, 2006, v. 49, n. 6, p. 1198, doi. 10.1007/s00125-006-0225-4

By:

Hermann, R.;
Lipponen, K.;
Kiviniemi, M.;
Kakko, T.;
Veijola, R.;
Simell, O.;
Knip, M.;
Ilonen, J.

Publication type:

Article

Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function.

Published in:

Diabetologia, 2006, v. 49, n. 1, p. 71, doi. 10.1007/s00125-005-0042-1

By:

Nielsen, L.;
Mortensen, H.;
Chiarelli, F.;
Holl, R.;
Swift, P.;
Beaufort, C.;
Pociot, F.;
Hougaard, P.;
Gammeltoft, S.;
Knip, M.;
Hansen, L.

Publication type:

Article

The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity.

Published in:

Diabetologia, 2005, v. 48, n. 9, p. 1766, doi. 10.1007/s00125-005-1844-x

By:

Hermann, Robert;
Laine, A. P.;
Veijola, R.;
Vahlberg, T.;
Simell, S.;
Lähde, J.;
Simell, O.;
Knip, M.;
Ilonen, J.

Publication type:

Article

Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study.

Published in:

2005

By:

Åkerblom, H. K.;
Virtanen, S. M.;
Ilonen, J.;
Savilahti, E.;
Vaarala, O.;
Reunanen, A.;
Teramo, K.;
Hämäläinen, A.-M.;
Paronen, J.;
Riikjärv, M.-A.;
Ormisson, A.;
Ludvigsson, J.;
Dosch, H.-M.;
Hakulinen, T.;
Knip, M.

Publication type:

Correction Notice

Relationship between the incidence of type 1 diabetes and maternal enterovirus antibodies: time trends and geographical variation.

Published in:

Diabetologia, 2005, v. 48, n. 7, p. 1280, doi. 10.1007/s00125-005-1780-9

By:

Viskari, H.;
Ludvigsson, J.;
Uibo, R.;
Salur, L.;
Marciulionyte, D.;
Hermann, R.;
Soltesz, G.;
Füchtenbusch, M.;
Ziegler, A.-G.;
Kondrashova, A.;
Romanov, A.;
Kaplan, B.;
Laron, Z.;
Koskela, P.;
Vesikari, T.;
Huhtala, H.;
Knip, M.;
Hyöty, H.

Publication type:

Article

Soluble adhesion molecules in pre-clinical Type 1 diabetes: a prospective study.

Published in:

2004

By:

Toivonen, A. M.;
Kulmala, P.;
Savola, K.;
Åkerblom, H. K.;
Knip, M.

Publication type:

Erratum

The HLA-DR phenotype modulates the humoral immune response to enterovirus antigens K. Sadeharju et al.: HLA-DR modulates enterovirus antibody levels.

Published in:

Diabetologia, 2003, v. 46, n. 8, p. 1100, doi. 10.1007/s00125-003-1157-x

By:

Sadeharju, K.;
Knip, M.;
Hiltunen, M.;
&Aringkerblom, H. K.;
Hyöty, H.

Publication type:

Article

—to: Pani MA, Van Autreve J, Van Der Auwera BJ, Gorus FK, Badenhoop K (2002) Non-transmitted maternal HLA DQ2 or DQ8 alleles and risk of Type I diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 45:1340–1343 R. Hermann et al.: Non-transmitted HLA haplotypes

Published in:

Diabetologia, 2003, v. 46, n. 4, p. 588, doi. 10.1007/s00125-003-1076-x

By:

Hermann, R.;
Veijola, R.;
Sipilä, I.;
Knip, M.;
Åkerblom, H. K.;
Simell, O.;
Ilonen, J.

Publication type:

Article

Soluble adhesion molecules in pre-clinical Type 1 diabetes: a prospective study A.M. Toivonen et al.: Soluble adhesion molecules in prediabetes.

Published in:

Diabetologia, 2003, v. 46, n. 4, p. 492, doi. 10.1007/s00125-003-1072-1

By:

Toivonen, A. M.;
Kulmala, P.;
Savola, K.;
Åkerblom, H. K.;
Knip, M.

Publication type:

Article

Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes—indication of an increased environmental pressure? R. Hermann et al.: Temporal changes in the HLA genotypes.

Published in:

Diabetologia, 2003, v. 46, n. 3, p. 420, doi. 10.1007/s00125-003-1045-4

By:

Hermann, R.;
Knip, M.;
Veijola, R.;
Simell, O.;
Laine, A.-P.;
Åkerblom, H. K.;
Groop, P.-H.;
Forsblom, C.;
Pettersson-Fernholm, K.;
Ilonen, J.

Publication type:

Article

Signs of beta-cell autoimmunity and HLA-defined diabetes susceptibility in the Finnish population: the sib cohort from the Type 1 Diabetes Prediction and Prevention Study M. Kukko et al.: Antibodies and genetic susceptibility to Type 1 diabetes.

Published in:

Diabetologia, 2003, v. 46, n. 1, p. 65, doi. 10.1007/s00125-002-0976-5

By:

Kukko, M.;
Kimpimäki, T.;
Kupila, A.;
Korhonen, S.;
Kulmala, P.;
Savola, K.;
Simell, T.;
Keskinen, P.;
Ilonen, J.;
Simell, O.;
Knip, M.

Publication type:

Article

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes P. Keskinen et al.: Insulin responses of prediabetic children.

Published in:

Diabetologia, 2002, v. 45, n. 12, p. 1639, doi. 10.1007/s00125-002-0981-8

By:

Keskinen, P.;
Korhonen, S.;
Kupila, A.;
Veijola, R.;
Erkkilä, S.;
Savolainen, H.;
Arvilommi, P.;
Simell, T.;
Ilonen, J.;
Knip, M.;
Simell, O.

Publication type:

Article

Nephrin is expressed in the pancreatic beta cells.

Published in:

Diabetologia, 2001, v. 44, n. 10, p. 1274

By:

Palmén, T.;
Ahola, H.;
Palgi, J.;
Aaltonen, P.;
Luimula, P.;
Wang, S.;
Jaakkola, I.;
Knip, M.;
Otonkoski, T.;
Holthöfer, H.

Publication type:

Article

Enterovirus antibody levels during the first two years of life in prediabetic autoantibody-positive children.

Published in:

Diabetologia, 2001, v. 44, n. 7, p. 818

By:

Sadeharju, K.;
Lönnrot, M.;
Kimpimäki, T.;
Savola, K.;
Erkkilä, S.;
Kalliokoski, T.;
Savolainen, P.;
Koskela, P.;
Ilonen, J.;
Simell, O.;
Knip, M.;
Hyöty, H.

Publication type:

Article

Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort.

Published in:

Diabetologia, 2001, v. 44, n. 3, p. 290, doi. 10.1007/s001250051616

By:

Kupila, A.;
Muona, P.;
Simell, T.;
Arvilommi, P.;
Savolainen, H.;
Hämäläinen, A.-M.;
Korhonen, S.;
Kimpimäki, T.;
Sjöroos, M.;
Ilonen, J.;
Knip, M.;
Simell, O.

Publication type:

Article

Short-term exclusive breastfeeding predisposes young children with increased genetic risk of Type I diabetes to progressive beta-cell autoimmunity.

Published in:

Diabetologia, 2001, v. 44, n. 1, p. 63

By:

Kimpimäki, T.;
Erkkola, M.;
Korhonen, S.;
Kupila, A.;
Virtanen, S. M.;
Ilonen, J.;
Simell, O.;
Knip, M.

Publication type:

Article

Safety of high-dose nicotinamide: a review.

Published in:

Diabetologia, 2000, v. 43, n. 11, p. 1337, doi. 10.1007/s001250051536

By:

Knip, M.;
Douek, I. F.;
Moore, W. P. T.;
Gillmor, H. A.;
McLean, A. E. M.;
Bingley, P. J.;
Gale, E. A. M.

Publication type:

Article

Neonatal Type I diabetes associated with maternal echovirus 6 infection: a case report.

Published in:

Diabetologia, 2000, v. 43, n. 10, p. 1235, doi. 10.1007/s001250051518

By:

Otonkoski, T.;
Roivainen, M.;
Vaarala, O.;
Dinesen, B.;
Leipälä, J. A.;
Hovi, T.;
Knip, M.

Publication type:

Article

Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren.

Published in:

Diabetologia, 2000, v. 43, n. 4, p. 457, doi. 10.1007/s001250051329

By:

Kulmala, P.;
Rahko, J.;
Savola, K.;
Vähäsalo, P.;
Veijola, R.;
Sjöroos, M.;
Reunanen, A.;
Ilonen, J.;
Knip, M.

Publication type:

Article

Epitope spreading and a varying but not disease-specific GAD65 antibody response in Type I diabetes.

Published in:

Diabetologia, 2000, v. 43, n. 2, p. 210

By:

Söhnlein, P.;
Müller, M.;
Syren, K.;
Hartmann, U.;
Böhm, B. O.;
Meinck, H. M.;
Knip, M.;
Akerblom, H. K.;
Richter, W.

Publication type:

Article

Impaired insulin secretion in non-diabetic offspring of probands with latent autoimmune diabetes mellitus in adults.

Published in:

Diabetologia, 2000, v. 43, n. 1, p. 69, doi. 10.1007/s001259900177

By:

Vauhkonen, I.;
Niskanen, L.;
Knip, M.;
Ilonen, J.;
Vanninen, E.;
Kainulainen, S.;
Uusitupa, M.;
Laakso, M.

Publication type:

Article

The association of the HLA-A24:02, B39:01 and B*39:06 alleles with type 1 diabetes is restricted to specific HLA-DR/DQ haplotypes in Finns.

Published in:

HLA: Immune Response Genetics, 2017, v. 89, n. 4, p. 215, doi. 10.1111/tan.12967

By:

Mikk, M.‐L.;
Heikkinen, T.;
El‐Amir, M. I.;
Kiviniemi, M.;
Laine, A.‐P.;
Härkönen, T.;
Veijola, R.;
Toppari, J.;
Knip, M.;
Ilonen, J.

Publication type:

Article