Works matching AU Knez, Damijan

Results: 29

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.

Published in:

ChemBioChem, 2021, v. 22, n. 4, p. 743, doi. 10.1002/cbic.202000700

By:

Petri, László;
Ábrányi‐Balogh, Péter;
Tímea, Imre;
Pálfy, Gyula;
Perczel, András;
Knez, Damijan;
Hrast, Martina;
Gobec, Martina;
Sosič, Izidor;
Nyíri, Kinga;
Vértessy, Beáta G.;
Jänsch, Niklas;
Desczyk, Charlotte;
Meyer‐Almes, Franz‐Josef;
Ogris, Iza;
Golič Grdadolnik, Simona;
Iacovino, Luca Giacinto;
Binda, Claudia;
Gobec, Stanislav;
Keserű, György M.

Publication type:

Article

Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3431, doi. 10.3390/cells10123431

By:

Kollár, Levente;
Gobec, Martina;
Proj, Matic;
Smrdel, Lara;
Knez, Damijan;
Imre, Tímea;
Gömöry, Ágnes;
Petri, László;
Ábrányi-Balogh, Péter;
Csányi, Dorottya;
Ferenczy, György G.;
Gobec, Stanislav;
Sosič, Izidor;
Keserű, György M.

Publication type:

Article

Biological Evaluation of Valeriana Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities—The Case of Valeriana carnosa Sm. (Caprifoliaceae) Studied in Mice.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 1, p. 129, doi. 10.3390/ph16010129

By:

Marcucci, Carolina;
Rademacher, Marina;
Kamecki, Fabiola;
Pastore, Valentina;
Bach, Hernán Gerónimo;
Ricco, Rafael Alejandro;
Wagner, Marcelo Luis;
Knez, Damijan;
Gobec, Stanislav;
Colettis, Natalia;
Marder, Mariel

Publication type:

Article

Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 12, p. 1484, doi. 10.3390/ph15121484

By:

Ábrányi-Balogh, Péter;
Keeley, Aaron;
Ferenczy, György G.;
Petri, László;
Imre, Tímea;
Grabrijan, Katarina;
Hrast, Martina;
Knez, Damijan;
Ilaš, Janez;
Gobec, Stanislav;
Keserű, György M.

Publication type:

Article

Synthesis of Indoline‐Based Benzhydroxamic Acids as Potential HDAC6 Inhibitors.

Published in:

ChemistrySelect, 2019, v. 4, n. 42, p. 12308, doi. 10.1002/slct.201902042

By:

Depetter, Yves;
Geurs, Silke;
Franceus, Jorick;
Knez, Damijan;
Desmet, Tom;
De Bosscher, Karolien;
De Wever, Olivier;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 498, doi. 10.1080/14756366.2019.1710502

By:

Pajk, Stane;
Knez, Damijan;
Košak, Urban;
Zorović, Maja;
Brazzolotto, Xavier;
Coquelle, Nicolas;
Nachon, Florian;
Colletier, Jacques-Philippe;
Živin, Marko;
Stojan, Jure;
Gobec, Stanislav

Publication type:

Article

Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1784, doi. 10.3390/ijms23031784

By:

Majc, Bernarda;
Habič, Anamarija;
Novak, Metka;
Rotter, Ana;
Porčnik, Andrej;
Mlakar, Jernej;
Župunski, Vera;
Fonović, Urša Pečar;
Knez, Damijan;
Zidar, Nace;
Gobec, Stanislav;
Kos, Janko;
Turnšek, Tamara Lah;
Pišlar, Anja;
Breznik, Barbara

Publication type:

Article

Synthesis and Initial Characterization of a Reversible, Selective 18F-Labeled Radiotracer for Human Butyrylcholinesterase.

Published in:

Molecular Imaging & Biology, 2021, v. 23, n. 4, p. 505, doi. 10.1007/s11307-021-01584-2

By:

Gentzsch, Christian;
Chen, Xinyu;
Spatz, Philipp;
Košak, Urban;
Knez, Damijan;
Nose, Naoko;
Gobec, Stanislav;
Higuchi, Takahiro;
Decker, Michael

Publication type:

Article

Molecular Mechanism of Labelling Functional Cysteines by Heterocyclic Thiones.

Published in:

ChemPhysChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cphc.202300596

By:

Mihalovits, Levente M.;
Kollár, Levente;
Bajusz, Dávid;
Knez, Damijan;
Bozovičar, Krištof;
Imre, Tímea;
Ferenczy, György G.;
Gobec, Stanislav;
Keserű, György M.

Publication type:

Article

Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease.

Published in:

Theranostics, 2021, v. 11, n. 13, p. 6542, doi. 10.7150/thno.54589

By:

Rejc, Luka;
Gómez-Vallejo, Vanessa;
Joya, Ana;
Moreno, Oscar;
Egimendia, Ander;
Castellnou, Pilar;
Ríos-Anglada, Xabier;
Cossío, Unai;
Baz, Zuriñe;
Passannante, Rossana;
Tobalina-Larrea, Ignacio;
Ramos-Cabrer, Pedro;
Giralt, Albert;
Sastre, Magdalena;
Capetillo-Zarate, Estibaliz;
Košak, Urban;
Knez, Damijan;
Gobec, Stanislav;
Marder, Mariel;
Martin, Abraham

Publication type:

Article

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ<sub>1−42</sub> Aggregation Inhibitors for Alzheimer's Disease Therapy.

Published in:

ChemMedChem, 2016, v. 11, n. 12, p. 1318, doi. 10.1002/cmdc.201500539

By:

Dgachi, Youssef;
Ismaili, Lhassane;
Knez, Damijan;
Benchekroun, Mohamed;
Martin, Hélène;
Szałaj, Natalia;
Wehle, Sarah;
Bautista‐Aguilera, Oscar M.;
Luzet, Vincent;
Bonnet, Alexandre;
Malawska, Barbara;
Gobec, Stanislav;
Chioua, Mourad;
Decker, Michael;
Chabchoub, Fakher;
Marco‐Contelles, José

Publication type:

Article

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Published in:

Angewandte Chemie, 2016, v. 128, n. 19, p. 5839, doi. 10.1002/ange.201600190

By:

Sosič, Izidor;
Gobec, Martina;
Brus, Boris;
Knez, Damijan;
Živec, Matej;
Konc, Janez;
Lešnik, Samo;
Ogrizek, Mitja;
Obreza, Aleš;
Žigon, Dušan;
Janežič, Dušanka;
Mlinarič ‐ Raščan, Irena;
Gobec, Stanislav

Publication type:

Article

Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment.

Published in:

Antioxidants, 2022, v. 11, n. 9, p. 1735, doi. 10.3390/antiox11091735

By:

Diez-Iriepa, Daniel;
Knez, Damijan;
Gobec, Stanislav;
Iriepa, Isabel;
de los Ríos, Cristóbal;
Bravo, Isaac;
López-Muñoz, Francisco;
Marco-Contelles, José;
Hadjipavlou-Litina, Dimitra

Publication type:

Article

WIDOCK: a reactive docking protocol for virtual screening of covalent inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 2, p. 223, doi. 10.1007/s10822-020-00371-5

By:

Scarpino, Andrea;
Petri, László;
Knez, Damijan;
Imre, Tímea;
Ábrányi-Balogh, Péter;
Ferenczy, György G.;
Gobec, Stanislav;
Keserű, György M.

Publication type:

Article

Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.

Published in:

Molecules, 2016, v. 21, n. 4, p. 410, doi. 10.3390/molecules21040410

By:

Hebda, Michalina;
Bajda, Marek;
Więckowska, Anna;
Szałaj, Natalia;
Pasieka, Anna;
Panek, Dawid;
Godyń, Justyna;
Wichur, Tomasz;
Knez, Damijan;
Gobec, Stanislav;
Malawska, Barbara

Publication type:

Article

Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides.

Published in:

Molecular Diversity, 2016, v. 20, n. 3, p. 667, doi. 10.1007/s11030-016-9668-9

By:

Grošelj, Uroš;
Golobič, Amalija;
Knez, Damijan;
Hrast, Martina;
Gobec, Stanislav;
Ričko, Sebastijan;
Svete, Jurij

Publication type:

Article

BUTYRYLCHOLINESTERASE INHIBITORS GRAFTED WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES: NOVEL MULTIFUNCTIONAL LIGANDS FOR ALZHEIMER'S DISEASE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 127

By:

Knez, Damijan;
Coquelle, Nicolas;
Pišlar, Anja;
Žakelj, Simon;
Jukič, Marko;
Sova, Matej;
Mravljak, Janez;
Nachon, Florian;
Brazzolotto, Xavier;
Kos, Janko;
Colletier, Jacques-Philippe;
Gobec, Stanislav

Publication type:

Article

MOLECULAR MODELING IN SEARCH OF NEW, MULTI-TARGET LIGANDS AGAINST ALZHEIMER'S DISEASE. EXPLORING THE BIOCHEMICAL MULTIVERSE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 75

By:

Jończyk, Jakub;
Panek, Dawid;
Więckowska, Anna;
Godyń, Justyna;
Bajda, Marek;
Wichur, Tomasz;
Pasieka, Anna;
Knez, Damijan;
Pišlar, Anja;
Korabecny, Jan;
Soukup, Ondrej;
Sepsova, Vendula;
Sabaté, Raimon;
Kos, Janko;
Gobec, Stanislav;
Malawska, Barbara

Publication type:

Article

FROM SELECTIVE BUTYRYLCHOLINESTERASE INHIBITORS TO MULTI-TARGET-DIRECTED LIGANDS AS LEAD COMPOUNDS FOR ALZHEIMER'S DISEASE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 70

By:

Košak, Urban;
Knez, Damijan;
Brus, Boris;
Gobec, Stanislav

Publication type:

Article

Repurposing of 8‐Hydroxyquinoline‐Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors.

Published in:

ChemMedChem, 2022, v. 17, n. 5, p. 1, doi. 10.1002/cmdc.202100694

By:

Gajic, Mihajlo;
Knez, Damijan;
Sosič, Izidor;
Mravljak, Janez;
Meden, Anže;
Košak, Urban;
Leitzbach, Luisa;
George, Sven;
Hofmann, Bettina;
Zivkovic, Aleksandra;
Steinhilber, Dieter;
Stark, Holger;
Gobec, Stanislav;
Smelcerovic, Andrija;
Anderluh, Marko

Publication type:

Article

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 19, p. 5745, doi. 10.1002/anie.201600190

By:

Sosič, Izidor;
Gobec, Martina;
Brus, Boris;
Knez, Damijan;
Živec, Matej;
Konc, Janez;
Lešnik, Samo;
Ogrizek, Mitja;
Obreza, Aleš;
Žigon, Dušan;
Janežič, Dušanka;
Mlinarič-Raščan, Irena;
Gobec, Stanislav

Publication type:

Article

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL BENZYLAMINE DERIVATIVES WITH HYDROXYETHYLAMINE PHARMACOPHORIC MOIETY AS MULTIFUNCTIONAL COMPOUNDS TARGETING CHOLINESTERASE, BETA-SECRETASE AND BETA-AMYLOID AGGREGATION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P280, doi. 10.1016/j.jalz.2017.06.171

By:

Malawska, Barbara;
Panek, Dawid;
Wieckowska, Anna;
Jonczyk, Jakub;
Godyn, Justyna;
Bajda, Marek;
Knez, Damijan;
Gobec, Stanislav

Publication type:

Article

N -Hydroxy- N -Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7437, doi. 10.3390/molecules27217437

By:

Bautista-Aguilera, Óscar M.;
Alonso, José M.;
Catto, Marco;
Iriepa, Isabel;
Knez, Damijan;
Gobec, Stanislav;
Marco-Contelles, José

Publication type:

Article

Screening of Big Pharma's Library against Various in-house Biological Targets.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144484

By:

Knez, Damijan;
Gobec, Stanislav;
Hrast, Martina

Publication type:

Article

4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B.

Published in:

Molecules, 2021, v. 26, n. 14, p. 4118, doi. 10.3390/molecules26144118

By:

Mazej, Tjaša;
Knez, Damijan;
Meden, Anže;
Gobec, Stanislav;
Sova, Matej

Publication type:

Article

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s Disease.

Published in:

Molecules, 2016, v. 21, n. 5, p. 634, doi. 10.3390/molecules21050634

By:

Dgachi, Youssef;
Bautista-Aguilera, Oscar M.;
Benchekroun, Mohamed;
Martin, Hélène;
Bonet, Alexandre;
Knez, Damijan;
Godyń, Justyna;
Malawska, Barbara;
Gobec, Stanislav;
Chioua, Mourad;
Janockova, Jana;
Soukup, Ondrej;
Chabchoub, Fakher;
Marco-Contelles, José;
Ismaili, Lhassane

Publication type:

Article

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

Published in:

Scientific Reports, 2016, p. 39495, doi. 10.1038/srep39495

By:

Košak, Urban;
Brus, Boris;
Knez, Damijan;
Šink, Roman;
Žakelj, Simon;
Trontelj, Jurij;
Pišlar, Anja;
Šlenc, Jasna;
Gobec, Martina;
Živin, Marko;
Tratnjek, Larisa;
Perše, Martina;
Sałat, Kinga;
Podkowa, Adrian;
Filipek, Barbara;
Nachon, Florian;
Brazzolotto, Xavier;
Więckowska, Anna;
Malawska, Barbara;
Stojan, Jure

Publication type:

Article

Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 1, p. 1, doi. 10.1007/s00018-021-04117-w

By:

Mitrović, Ana;
Završnik, Janja;
Mikhaylov, Georgy;
Knez, Damijan;
Pečar Fonović, Urša;
Matjan Štefin, Petra;
Butinar, Miha;
Gobec, Stanislav;
Turk, Boris;
Kos, Janko

Publication type:

Article

Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds.

Published in:

Acta Chimica Slovenica, 2023, v. 70, n. 4, p. 545, doi. 10.17344/acsi.2023.8460

By:

Gršič, Marija;
Meden, Anže;
Knez, Damijan;
Jukič, Marko;
Svete, Jurij;
Gobec, Stanislav;
Grošelj, Uroš

Publication type:

Article