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Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40536-y
By:
- Roth Flach, Rachel J.;
- Bollinger, Eliza;
- Reyes, Allan R.;
- Laforest, Brigitte;
- Kormos, Bethany L.;
- Liu, Shenping;
- Reese, Matthew R.;
- Martinez Alsina, Luis A.;
- Buzon, Leanne;
- Zhang, Yuan;
- Bechle, Bruce;
- Rosado, Amy;
- Sahasrabudhe, Parag V.;
- Knafels, John;
- Bhattacharya, Samit K.;
- Omoto, Kiyoyuki;
- Stansfield, John C.;
- Hurley, Liam D.;
- Song, LouJin;
- Luo, Lina
Publication type:
Article
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40536-y
By:
- Roth Flach, Rachel J.;
- Bollinger, Eliza;
- Reyes, Allan R.;
- Laforest, Brigitte;
- Kormos, Bethany L.;
- Liu, Shenping;
- Reese, Matthew R.;
- Martinez Alsina, Luis A.;
- Buzon, Leanne;
- Zhang, Yuan;
- Bechle, Bruce;
- Rosado, Amy;
- Sahasrabudhe, Parag V.;
- Knafels, John;
- Bhattacharya, Samit K.;
- Omoto, Kiyoyuki;
- Stansfield, John C.;
- Hurley, Liam D.;
- Song, LouJin;
- Luo, Lina
Publication type:
Article
Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65762-y
By:
- Gerstenberger, Brian S.;
- Banker, Mary Ellen;
- Clark, James D.;
- Dowty, Martin E.;
- Fensome, Andrew;
- Gifford, Roger;
- Griffor, Matthew C.;
- Hegen, Martin;
- Hollingshead, Brett D.;
- Knafels, John D.;
- Lin, Tsung H.;
- Smith, James F.;
- Vajdos, Felix F.
Publication type:
Article
Crystal structure of the bacterial protein export chaperone SecB.
Published in:
Nature Structural Biology, 2000, v. 7, n. 12, p. 1172, doi. 10.1038/82040
By:
- Xu, Zhaohui;
- Knafels, John D.;
- Yoshino, Kae
Publication type:
Article
Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor.
Published in:
Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 3, p. 450, doi. 10.1110/ps.073324108
By:
- Mochalkin, Igor;
- Knafels, John D.;
- Lightle, Sandra
Publication type:
Article

Found: 5

Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.

Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.

Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences.

Crystal structure of the bacterial protein export chaperone SecB.

Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor.