Works matching AU Klimko, Christopher P.

Results: 32

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1603710

By:

Biryukov, Sergei S.;
Rasley, Amy;
Davies, Michael L.;
Klimko, Christopher P.;
Dankmeyer, Jennifer L.;
Hunter, Melissa;
Rill, Nathaniel O.;
Shoe, Jennifer L.;
Miller, Jeremy;
Talyansky, Yuli;
Sullinger, Barbara;
Herrera, Matheo;
Huang, Daniel;
Bautista, Leslie;
Pepe, Lucy;
Peters, Sandra K. G.;
Xander, Christian J.;
Martinez, Elsie E.;
Toothman, Ronald G.;
Mlynek, Kevin D.

Publication type:

Article

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612540

By:

Davies, Michael L.;
Biryukov, Sergei S.;
Klimko, Christopher P.;
Dankmeyer, Jennifer L.;
Rill, Nathaniel O.;
Hunter, Melissa;
Braun, Christopher T.;
Patrick, Deven W.;
David, Tyrique D.;
Kwilas, Steven A.;
Rodriguez, Carlos I.;
Smith, Brian A.;
Qiu, Ju;
Hooper, Jay W.;
Cote, Christopher K.

Publication type:

Article

Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596265

By:

Biryukov, Sergei S.;
Cote, Christopher K.;
Klimko, Christopher P.;
Dankmeyer, Jennifer L.;
Rill, Nathaniel O.;
Hunter, Melissa;
Davies, Michael L.;
Hedrick, Zander M.;
Shoe, Jennifer L.;
Schmidt, Lindsey K.;
Orne, Caitlyn E.;
Qiu, Ju;
Welkos, Susan L.;
Burtnick, Mary N.;
Brett, Paul J.;
DeShazer, David

Publication type:

Article

Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice.

Published in:

Frontiers in Cellular & Infection Microbiology, 2016, v. 6, p. 1, doi. 10.3389/fcimb.2016.00021

By:

Bozue, Joel A.;
Chaudhury, Sidhartha;
Amemiya, Kei;
Chua, Jennifer;
Cote, Christopher K.;
Toothman, Ronald G.;
Dankmeyer, Jennifer L.;
Klimko, Christopher P.;
Wilhelmsen, Catherine L.;
Raymond, Jolynn W.;
Zavaljevski, Nela;
Reifman, Jaques;
Wallqvist, Anders

Publication type:

Article

Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.593542

By:

Biot, Fabrice V.;
Bachert, Beth A.;
Mlynek, Kevin D.;
Toothman, Ronald G.;
Koroleva, Galina I.;
Lovett, Sean P.;
Klimko, Christopher P.;
Palacios, Gustavo F.;
Cote, Christopher K.;
Ladner, Jason T.;
Bozue, Joel A.

Publication type:

Article

Efficacy of Treatment with the Antibiotic Novobiocin against Infection with Bacillus anthracis or Burkholderia pseudomallei.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 12, p. 1685, doi. 10.3390/antibiotics11121685

By:

Klimko, Christopher P.;
Welkos, Susan L.;
Shoe, Jennifer L.;
Mou, Sherry;
Hunter, Melissa;
Rill, Nathaniel O.;
DeShazer, David;
Cote, Christopher K.

Publication type:

Article

Predictive and Experimental Immunogenicity of Burkholderia Collagen-like Protein 8-Derived Antigens.

Published in:

Vaccines, 2021, v. 9, n. 11, p. 1219, doi. 10.3390/vaccines9111219

By:

Grund, Megan E.;
Kramarska, Eliza;
Choi, Soo Jeon;
McNitt, Dudley H.;
Klimko, Christopher P.;
Rill, Nathaniel O.;
Dankmeyer, Jennifer L.;
Shoe, Jennifer L.;
Hunter, Melissa;
Fetterer, David P.;
Hedrick, Zander M.;
Velez, Ivan;
Biryukov, Sergei S.;
Cote, Christopher K.;
Berisio, Rita;
Lukomski, Slawomir

Publication type:

Article

Protection Elicited by Attenuated Live Yersinia pestis Vaccine Strains against Lethal Infection with Virulent Y. pestis.

Published in:

Vaccines, 2021, v. 9, n. 2, p. 161, doi. 10.3390/vaccines9020161

By:

Cote, Christopher K.;
Biryukov, Sergei S.;
Klimko, Christopher P.;
Shoe, Jennifer L.;
Hunter, Melissa;
Rosario-Acevedo, Raysa;
Fetterer, David P.;
Moody, Krishna L.;
Meyer, Joshua R.;
Rill, Nathaniel O.;
Dankmeyer, Jennifer L.;
Worsham, Patricia L.;
Bozue, Joel A.;
Welkos, Susan L.;
Golubovskaya, Vita

Publication type:

Article

The Use of Analgesics during Vaccination with a Live Attenuated Yersinia pestis Vaccine Alters the Resulting Immune Response in Mice.

Published in:

Vaccines, 2019, v. 7, n. 4, p. 205, doi. 10.3390/vaccines7040205

By:

Culbreth, Marilynn J.;
Biryukov, Sergei S.;
Shoe, Jennifer L.;
Dankmeyer, Jennifer L.;
Hunter, Melissa;
Klimko, Christopher P.;
Rosario-Acevedo, Raysa;
Fetterer, David P.;
Moreau, Alicia M.;
Welkos, Susan L.;
Cote, Christopher K.

Publication type:

Article

Deletion of Two Genes in Burkholderia pseudomallei MSHR668 That Target Essential Amino Acids Protect Acutely Infected BALB/c Mice and Promote Long Term Survival.

Published in:

Vaccines, 2019, v. 7, n. 4, p. 196, doi. 10.3390/vaccines7040196

By:

Amemiya, Kei;
Dankmeyer, Jennifer L.;
Biryukov, Sergei S.;
Treviño, Sylvia R.;
Klimko, Christopher P.;
Mou, Sherry M.;
Fetterer, David P.;
Garnes, Preston G.;
Cote, Christopher K.;
Worsham, Patricia L.;
DeShazer, David

Publication type:

Article

Development, Phenotypic Characterization and Genomic Analysis of a Francisella tularensis Panel for Tularemia Vaccine Testing.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.725776

By:

Bachert, Beth A.;
Richardson, Joshua B.;
Mlynek, Kevin D.;
Klimko, Christopher P.;
Toothman, Ronald G.;
Fetterer, David P.;
Luquette, Andrea E.;
Chase, Kitty;
Storrs, Jessica L.;
Rogers, Ashley K.;
Cote, Christopher K.;
Rozak, David A.;
Bozue, Joel A.

Publication type:

Article

Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172627

By:

Bearss, Jeremy J.;
Hunter, Melissa;
Dankmeyer, Jennifer L.;
Fritts, Kristen A.;
Klimko, Christopher P.;
Weaver, Chris H.;
Shoe, Jennifer L.;
Quirk, Avery V.;
Toothman, Ronald G.;
Webster, Wendy M.;
Fetterer, David P.;
Bozue, Joel A.;
Worsham, Patricia L.;
Welkos, Susan L.;
Amemiya, Kei;
Cote, Christopher K.

Publication type:

Article

The rLVS ΔcapB/iglABC vaccine provides potent protection in Fischer rats against inhalational tularemia caused by various virulent Francisella tularensis strains.

Published in:

Human Vaccines & Immunotherapeutics, 2023, v. 19, n. 3, p. 1, doi. 10.1080/21645515.2023.2277083

By:

Mlynek, Kevin D.;
Cline, Curtis R.;
Biryukov, Sergei S.;
Toothman, Ronald G.;
Bachert, Beth A.;
Klimko, Christopher P.;
Shoe, Jennifer L.;
Hunter, Melissa;
Hedrick, Zander M.;
Dankmeyer, Jennifer L.;
Mou, Sherry;
Fetterer, David P.;
Qiu, Ju;
Lee, Eric D.;
Cote, Christopher K.;
Jia, Qingmei;
Horwitz, Marcus A.;
Bozue, Joel A.

Publication type:

Article

Functional assays to screen and select monoclonal antibodies that target Yersinia pestis.

Published in:

Human Vaccines & Immunotherapeutics, 2023, v. 19, n. 2, p. 1, doi. 10.1080/21645515.2023.2216085

By:

Biryukov, Sergei S.;
Rill, Nathaniel O.;
Klimko, Christopher P.;
Dankmeyer, Jennifer L.;
Shoe, Jennifer L.;
Hunter, Melissa;
Talyansky, Yuli;
Hau, Derrick;
Gates-Hollingsworth, Marcellene A.;
Pandit, Sujata G.;
Fetterer, David P.;
Qiu, Ju;
Davies, Michael L.;
AuCoin, David P.;
Cote, Christopher K.

Publication type:

Article

Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 2, p. 1, doi. 10.1371/journal.pntd.0009125

By:

Trevino, Sylvia R.;
Dankmeyer, Jennifer L.;
Fetterer, David P.;
Klimko, Christopher P.;
Raymond, Jo Lynne W.;
Moreau, Alicia M.;
Soffler, Carl;
Waag, David M.;
Worsham, Patricia L.;
Amemiya, Kei;
Ruiz, Sara I.;
Cote, Christopher K.;
Krakauer, Teresa

Publication type:

Article

Characterization of two affinity matured Anti-Yersinia pestis F1 human antibodies with medical countermeasure potential.

Published in:

PLoS ONE, 2024, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0305034

By:

Velappan, Nileena;
Biryukov, Sergei S.;
Rill, Nathaniel O.;
Klimko, Christopher P.;
Rosario-Acevedo, Raysa;
Shoe, Jennifer L.;
Hunter, Melissa;
Dankmeyer, Jennifer L.;
Fetterer, David P.;
Bedinger, Daniel;
Phipps, Mary E.;
Watt, Austin J.;
Abergel, Rebecca J.;
Dichosa, Armand;
Kozimor, Stosh A.;
Cote, Christopher K.;
Lillo, Antonietta M.

Publication type:

Article

Sex differences in immune protection in mice conferred by heterologous vaccines for pneumonic plague.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1397579

By:

Davies, Michael L.;
Biryukov, Sergei S.;
Rill, Nathaniel O.;
Klimko, Christopher P.;
Hunter, Melissa;
Dankmeyer, Jennifer L.;
Miller, Jeremy A.;
Shoe, Jennifer L.;
Mlynek, Kevin D.;
Talyansky, Yuli;
Toothman, Ronald G.;
Ju Qiu;
Bozue, Joel A.;
Cote, Christopher K.

Publication type:

Article

Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0208277

By:

Trevino, Sylvia R.;
Klimko, Christopher P.;
Reed, Matthew C.;
Aponte-Cuadrado, Michael J.;
Hunter, Melissa;
Shoe, Jennifer L.;
Meyer, Joshua R.;
Dankmeyer, Jennifer L.;
Biryukov, Sergei S.;
Quirk, Avery V.;
Fritts, Kristen A.;
Kern, Steven J.;
Fetterer, David P.;
Kohler, Lara J.;
Toothman, Ronald G.;
Bozue, Joel A.;
Schellhase, Christopher W.;
Kreiselmeier, Norman;
Daye, Sharon P.;
Welkos, Susan L.

Publication type:

Article

Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague.

Published in:

Antibodies (2073-4468), 2023, v. 12, n. 2, p. 33, doi. 10.3390/antib12020033

By:

Biryukov, Sergei S.;
Wu, Hua;
Dankmeyer, Jennifer L.;
Rill, Nathaniel O.;
Klimko, Christopher P.;
Egland, Kristi A.;
Shoe, Jennifer L.;
Hunter, Melissa;
Fetterer, David P.;
Qiu, Ju;
Davies, Michael L.;
Bausch, Christoph L.;
Sullivan, Eddie J.;
Luke, Thomas;
Cote, Christopher K.

Publication type:

Article

Impact of Toll-Like Receptor-Specific Agonists on the Host Immune Response to the Yersinia pestis Plague rF1V Vaccine.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.726416

By:

Biryukov, Sergei;
Dankmeyer, Jennifer L.;
Shamsuddin, Zain;
Velez, Ivan;
Rill, Nathaniel O.;
Rosario-Acevedo, Raysa;
Klimko, Christopher P.;
Shoe, Jennifer L.;
Hunter, Melissa;
Ward, Michael D.;
Cazares, Lisa H.;
Fetterer, David P.;
Bozue, Joel A.;
Worsham, Patricia L.;
Cote, Christopher K.;
Amemiya, Kei

Publication type:

Article

Clindamycin Protects Nonhuman Primates Against Inhalational Anthrax But Does Not Enhance Reduction of Circulating Toxin Levels When Combined With Ciprofloxacin.

Published in:

2021

By:

Vietri, Nicholas J;
Tobery, Steven A;
Chabot, Donald J;
Ingavale, Susham;
Somerville, Brandon C;
Miller, Jeremy A;
Schellhase, Chris W;
Twenhafel, Nancy A;
Fetterer, David P;
Cote, Christopher K;
Klimko, Christopher P;
Boyer, Anne E;
Woolfitt, Adrian R;
Barr, John R;
Wright, Mary E;
Friedlander, Arthur M

Publication type:

journal article

A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence.

Published in:

Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.01343

By:

Bachert, Beth A.;
Biryukov, Sergei S.;
Chua, Jennifer;
Rodriguez, Sabrina A.;
Toothman, Ronald G.;
Cote, Christopher K.;
Klimko, Christopher P.;
Hunter, Melissa;
Shoe, Jennifer L.;
Williams, Janice A.;
Kuehl, Kathleen A.;
Biot, Fabrice V.;
Bozue, Joel A.

Publication type:

Article

Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124667

By:

Welkos, Susan L.;
Klimko, Christopher P.;
Kern, Steven J.;
Bearss, Jeremy J.;
Bozue, Joel A.;
Bernhards, Robert C.;
Trevino, Sylvia R.;
Waag, David M.;
Amemiya, Kei;
Worsham, Patricia L.;
Cote, Christopher K.

Publication type:

Article

Interrogation of the Burkholderia pseudomallei Genome to Address Differential Virulence among Isolates.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0115951

By:

Challacombe, Jean F.;
Stubben, Chris J.;
Klimko, Christopher P.;
Welkos, Susan L.;
Kern, Steven J.;
Bozue, Joel A.;
Worsham, Patricia L.;
Cote, Christopher K.;
Wolfe, Daniel N.

Publication type:

Article

The Impact of Age and Sex on Mouse Models of Melioidosis.

Published in:

Pathogens, 2020, v. 9, n. 2, p. 113, doi. 10.3390/pathogens9020113

By:

Klimko, Christopher P.;
Treviño, Sylvia R.;
Moreau, Alicia M.;
Aponte Cuadrado, Michael J.;
Meyer, Joshua R.;
Fetterer, David P.;
Welkos, Susan L.;
Worsham, Patricia L.;
Kreiselmeier, Norman;
Soffler, Carl;
Cote, Christopher K.

Publication type:

Article

Layered and integrated medical countermeasures against Burkholderia pseudomallei infections in C57BL/6 mice.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.965572

By:

Klimko, Christopher P.;
Shoe, Jennifer L.;
Rill, Nathaniel O.;
Hunter, Melissa;
Dankmeyer, Jennifer L.;
Talyansky, Yuli;
Schmidt, Lindsey K.;
Orne, Caitlyn E.;
Fetterer, David P.;
Biryukov, Sergei S.;
Burtnick, Mary N.;
Brett, Paul J.;
DeShazer, David;
Cote, Christopher K.

Publication type:

Article

Evaluation of two dierent vaccine platforms for immunization against melioidosis and glanders.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.965518

By:

Biryukov, Sergei S.;
Cote, Christopher K.;
Klimko, Christopher P.;
Dankmeyer, Jennifer L.;
Rill, Nathaniel O.;
Shoe, Jennifer L.;
Hunter, Melissa;
Shamsuddin, Zain;
Velez, Ivan;
Hedrick, Zander M.;
Rosario-Acevedo, Raysa;
Talyansky, Yuli;
Schmidt, Lindsey K.;
Orne, Caitlyn E.;
Fetterer, David P.;
Burtnick, Mary N.;
Brett, Paul J.;
Welkos, Susan L.;
DeShazer, David

Publication type:

Article

Virulence of Burkholderia pseudomallei ATS2021 Unintentionally Imported to United States in Aromatherapy Spray.

Published in:

Emerging Infectious Diseases, 2024, v. 30, n. 10, p. 2056, doi. 10.3201/eid3010.240084

By:

Cote, Christopher K.;
Mlynek, Kevin D.;
Klimko, Christopher P.;
Biryukov, Sergei S.;
Mou, Sherry;
Hunter, Melissa;
Rill, Nathaniel O.;
Dankmeyer, Jennifer L.;
Miller, Jeremy A.;
Talyansky, Yuli;
Davies, Michael L.;
Meinig, J. Matthew;
Halasohoris, Stephanie A.;
Gray, Annette M.;
Spencer, Jade L.;
Babyak, Ashley L.;
Hourihan, M. Kelly;
Curry, Bobby J.;
Toothman, Ronald G.;
Ruiz, Sara I.

Publication type:

Article

Formaldehyde and Glutaraldehyde Inactivation of Bacterial Tier 1 Select Agents in Tissues.

Published in:

2019

By:

Chua, Jennifer;
Bozue, Joel A.;
Klimko, Christopher P.;
Shoe, Jennifer L.;
Ruiz, Sara I.;
Jensen, Christopher L.;
Tobery, Steven A.;
Crumpler, Jared M.;
Chabot, Donald J.;
Quirk, Avery V.;
Hunter, Melissa;
Harbourt, David E.;
Friedlander, Arthur M.;
Cote, Christopher K.

Publication type:

journal article

Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores.

Published in:

2018

By:

Plaut, Roger D.;
Staab, Andrea B.;
Munson, Mark A.;
Gebhardt, Joan S.;
Klimko, Christopher P.;
Quirk, Avery V.;
Cote, Christopher K.;
Buhr, Tony L.;
Rossmaier, Rebecca D.;
Bernhards, Robert C.;
Love, Courtney E.;
Berk, Kimberly L.;
Abshire, Teresa G.;
Rozak, David A.;
Beck, Linda C.;
Stibitz, Scott;
Goodwin, Bruce G.;
Smith, Michael A.;
Sozhamannan, Shanmuga

Publication type:

journal article

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections.

Published in:

PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008836

By:

Alameh, Saleem;
Bartolo, Gloria;
O'Brien, Summer;
Henderson, Elizabeth A.;
Gonzalez, Leandra O.;
Hartmann, Stella;
Klimko, Christopher P.;
Shoe, Jennifer L.;
Cote, Christopher K.;
Grill, Laurence K.;
Levitin, Anastasia;
Martchenko Shilman, Mikhail

Publication type:

Article

Efficacy of delafloxacin against the biothreat pathogen Bacillus anthracis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 3, p. 810, doi. 10.1093/jac/dkad015

By:

McCurdy, Sandra;
Halasohoris, Stephanie A;
Babyak, Ashley L;
Lembirik, Sanae;
Hoover, Randall;
Hickman, Mark;
Scarff, Jennifer;
Klimko, Christopher P;
Cote, Christopher K;
Meinig, J Matthew

Publication type:

Article