Works by Kleinerman, Eugenie S.

Results: 47

STAT3 inhibition in combination with CD47 blockade inhibits osteosarcoma lung metastasis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608375

By:

Shrestha, Pradeep;
Shrestha, Rejeena;
Zhou, You;
Zielinski, Rafal;
Priebe, Waldemar;
Kleinerman, Eugenie S.

Publication type:

Article

Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells.

Published in:

2013

By:

Hollomon, Mario G.;
Gordon, Nancy;
Santiago-O'Farrill, Janice M.;
Kleinerman, Eugenie S.

Publication type:

journal article

VEGF165 is necessary to the metastatic potential of Fas- osteosarcoma cells but will not rescue the Fas+ cells.

Published in:

Journal of Experimental Therapeutics & Oncology, 2008, v. 7, n. 2, p. 89

By:

Jia, Shu-Fang;
Guan, Hui;
Duan, Xiaoping;
Kleinerman, Eugenie S.

Publication type:

Article

Adenovirus-mediated human topoisomerase IIα gene transfer increases the sensitivity of etoposide-resistant human and mouse breast cancer cells.

Published in:

Acta Oncologica, 2005, v. 44, n. 3, p. 240, doi. 10.1080/02841860510029653

By:

Asano, Takeshi;
Kleinerman, Eugenie S.;
Zwelling, Leonard A.;
Zhichao Zhou;
Fukunaga, Yoshitaka

Publication type:

Article

EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology.

Published in:

Cancer (0008543X), 2014, v. 120, n. 4, p. 579, doi. 10.1002/cncr.28555

By:

Zhou, Zhichao;
Yu, Ling;
Kleinerman, Eugenie S.

Publication type:

Article

CAPER-α alternative splicing regulates the expression of vascular endothelial growth factor₁₆₅ in Ewing sarcoma cells.

Published in:

2012

By:

Huang G;
Zhou Z;
Wang H;
Kleinerman ES;
Huang, Gangxiong;
Zhou, Zhichao;
Wang, Hua;
Kleinerman, Eugenie S

Publication type:

journal article

CAPER-α alternative splicing regulates the expression of vascular endothelial growth factor165 in Ewing sarcoma cells.

Published in:

Cancer (0008543X), 2012, v. 118, n. 8, p. 2106, doi. 10.1002/cncr.26488

By:

Huang, Gangxiong;
Zhou, Zhichao;
Wang, Hua;
Kleinerman, Eugenie S.

Publication type:

Article

Effect of the histone deacetylase inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastases.

Published in:

Cancer (0008543X), 2011, v. 117, n. 15, p. 3457, doi. 10.1002/cncr.25884

By:

Koshkina, Nadezhda V.;
Rao-Bindal, Krithi;
Kleinerman, Eugenie S.

Publication type:

Article

Platelet-derived growth factor receptor β inhibition increases tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity.

Published in:

Cancer (0008543X), 2010, v. 116, n. 16, p. 3892, doi. 10.1002/cncr.25107

By:

Wang, Yongxin;
Mandal, Deendayal;
Wang, Suizhau;
Kleinerman, Eugenie S.;
Pollock, Raphael E.;
Lev, Dina;
Hayes-Jordan, Andrea

Publication type:

Article

Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: a report from the Children's Oncology Group.

Published in:

2009

By:

Chou AJ;
Kleinerman ES;
Krailo MD;
Chen Z;
Betcher DL;
Healey JH;
Conrad EU 3rd;
Nieder ML;
Weiner MA;
Wells RJ;
Womer RB;
Meyers PA;
Children's Oncology Group;
Chou, Alexander J;
Kleinerman, Eugenie S;
Krailo, Mark D;
Chen, Zhengjia;
Betcher, Donna L;
Healey, John H;
Conrad, Ernest U 3rd

Publication type:

journal article

Addition of Muramyl Tripeptide to Chemotherapy for Patients With Newly Diagnosed Metastatic Osteosarcoma.

Published in:

Cancer (0008543X), 2009, v. 115, n. 22, p. 5339, doi. 10.1002/cncr.24566

By:

Chou, Alexander J.;
Kleinerman, Eugenie S.;
Krailo, Mark D.;
Zhengjia Chen;
Betcher, Donna L.;
Healey, John H.;
Conrad Ill, Ernest U.;
Nieder, Michael L.;
Weiner, Michael A.;
Wells, Robert J.;
Womer, Richard B.;
Meyers, Paul A.

Publication type:

Article

Murine Bone Marrow-derived Mesenchymal Stem Cells as Vehicles for Interleukin-12 Gene Delivery Into Ewing Sarcoma Tumors.

Published in:

Cancer (0008543X), 2009, v. 115, n. 1, p. 13, doi. 10.1002/cncr.24013

By:

Xiaoping Duan;
Hui Guan;
Ying Cao;
Kleinerman, Eugenie S.

Publication type:

Article

Vascular modulation through exercise improves chemotherapy efficacy in Ewing sarcoma.

Published in:

2019

By:

Morrell, Miriam B. G.;
Alvarez‐Florez, Claudia;
Zhang, Aiqian;
Kleinerman, Eugenie S.;
Savage, Hannah;
Marmonti, Enrica;
Park, Minjeong;
Shaw, Angela;
Schadler, Keri L.;
Alvarez-Florez, Claudia

Publication type:

journal article

Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis.

Published in:

Pediatric Blood & Cancer, 2014, v. 61, n. 8, p. 1362, doi. 10.1002/pbc.25019

By:

Guma, Sergei R.;
Lee, Dean A.;
Ling, Yu;
Gordon, Nancy;
Kleinerman, Eugenie S.

Publication type:

Article

Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis.

Published in:

Pediatric Blood & Cancer, 2014, v. 61, n. 4, p. 618, doi. 10.1002/pbc.24801

By:

Guma, Sergei R.;
Lee, Dean A.;
Yu, Ling;
Gordon, Nancy;
Hughes, Dennis;
Stewart, John;
Wang, Wei Lien;
Kleinerman, Eugenie S.

Publication type:

Article

Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts.

Published in:

Pediatric Blood & Cancer, 2013, v. 60, n. 4, p. 575, doi. 10.1002/pbc.24412

By:

Rao‐Bindal, Krithi;
Rao, Chethan K.;
Yu, Ling;
Kleinerman, Eugenie S.

Publication type:

Article

Short-Term Changes in Skeletal Muscle Mass After Anthracycline Administration in Adolescent and Young Adult Sarcoma Patients.

Published in:

Journal of Adolescent & Young Adult Oncology, 2022, v. 11, n. 3, p. 320, doi. 10.1089/jayao.2021.0107

By:

Wooten, Savannah V.;
Roth, Michael;
Livingston, John Andrew;
Hildebrandt, Michelle A.T.;
Chandra, Joya;
Amini, Behrang;
Kleinerman, Eugenie S.;
Gilchrist, Susan C.

Publication type:

Article

Short-Term Changes in Cardiac Function in Osteosarcoma Patients Receiving Anthracyclines.

Published in:

Journal of Adolescent & Young Adult Oncology, 2019, v. 8, n. 3, p. 385, doi. 10.1089/jayao.2018.0141

By:

Gilchrist, Susan C.;
Roth, Michael;
Livingston, J. Andrew;
Hildebrandt, Michelle A.T.;
Kleinerman, Eugenie S.;
Banchs, Jose

Publication type:

Article

Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1.

Published in:

Sarcoma, 2018, p. 1, doi. 10.1155/2018/8694397

By:

Markel, Justin E.;
Noore, Jabeen;
Emery, Eric J.;
Bobnar, Harley J.;
Kleinerman, Eugenie S.;
Lindsey, Brock A.

Publication type:

Article

Aerosol Gemcitabine after Amputation Inhibits Osteosarcoma Lung Metastases but Not Wound Healing.

Published in:

Sarcoma, 2018, p. 1, doi. 10.1155/2018/3143096

By:

Kleinerman, Eugenie S.;
Yu, Ling;
Dao, Jasmine;
Hayes-Jordan, Andrea A.;
Lindsey, Brock;
Kawedia, Jitesh D.;
Stewart, John;
Gordon, Nancy

Publication type:

Article

Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents.

Published in:

2011

By:

Stewart, Keri S.;
Kleinerman, Eugenie S.

Publication type:

Journal Article

Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents.

Published in:

Sarcoma, 2011, p. 1, doi. 10.1155/2011/165837

By:

Stewart, Keri S.;
Kleinerman, Eugenie S.

Publication type:

Article

Expression of Granulocyte-Colony-Stimulating Factor and Its Receptor in Human Ewing Sarcoma Cells and Patient Tumor Specimens.

Published in:

Cancer (0008543X), 2007, v. 110, n. 7, p. 1568, doi. 10.1002/cncr.22964

By:

Morales-Arias, Jaime;
Meyers, Paul A.;
Bolontrade, Marcela F.;
Rodriguez, Nidra;
Zhichao Zhou;
Reddy, Krishna;
Chou, Alexander J.;
Koshkina, Nadezhda V.;
Kleinerman, Eugenie S.

Publication type:

Article

Intranasal interleukin-12 gene therapy enhanced the activity of ifosfamide against osteosarcoma lung metastases.

Published in:

Cancer (0008543X), 2006, v. 106, n. 6, p. 1382, doi. 10.1002/cncr.21744

By:

Duan, Xiaoping;
Jia, Shu-Fang;
Koshkina, Nadezhda;
Kleinerman, Eugenie S.

Publication type:

Article

Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma.

Published in:

Cancer (0008543X), 2005, v. 104, n. 8, p. 1713

By:

Zhichao Zhou;
Hui Guan;
Xiaoping Duan;
Eugenie S. Kleinerman

Publication type:

Article

α4 integrin increases anoikis of human osteosarcoma cells.

Published in:

Journal of Cellular Biochemistry, 2003, v. 88, n. 5, p. 1038, doi. 10.1002/jcb.10465

By:

Rex A. W. Marco;
C. Marcela Díaz-Montero;
James N. Wygant;
Eugenie S. Kleinerman;
Bradley W. McIntyre

Publication type:

Article

Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs.

Published in:

International Journal of Cancer, 2009, v. 125, n. 11, p. 2586, doi. 10.1002/ijc.24665

By:

Pradelli, Emmanuelle;
Karimdjee-Soilihi, Babou;
Michiels, Jean-François;
Ricci, Jean-Ehrland;
Millet, Marie-Ange;
Vandenbos, Fanny;
Sullivan, Timothy J.;
Collins, Tassie L.;
Johnson, Michael G.;
Medina, Julio C.;
Kleinerman, Eugenie S.;
Schmid-Alliana, Annie;
Schmid-Antomarchi, Heidy

Publication type:

Article

Stromal cell-derived factor-1 stimulates vasculogenesis and enhances Ewing's sarcoma tumor growth in the absence of vascular endothelial growth factor.

Published in:

International Journal of Cancer, 2008, v. 123, n. 4, p. 831, doi. 10.1002/ijc.23582

By:

Reddy, Krishna;
Zhou, Zhichao;
Jia, Shu-Fang;
Lee, Tim H.;
Morales-Arias, Jaime;
Cao, Ying;
Kleinerman, Eugenie S.

Publication type:

Article

CD103 + cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.

Published in:

Cancers, 2024, v. 16, n. 19, p. 3251, doi. 10.3390/cancers16193251

By:

Yang, Yuanzheng;
Zhou, Yifan;
Wang, Jian;
Zhou, You;
Watowich, Stephanie S.;
Kleinerman, Eugenie S.

Publication type:

Article

Pramlintide: A Novel Therapeutic Approach for Osteosarcoma through Metabolic Reprogramming.

Published in:

Cancers, 2022, v. 14, n. 17, p. 4310, doi. 10.3390/cancers14174310

By:

Yang, Yuanzheng;
Peng, Zhanglong;
Flores, Elsa R.;
Kleinerman, Eugenie S.

Publication type:

Article

Exercise Inhibits Doxorubicin-Induced Damage to Cardiac Vessels and Activation of Hippo/YAP-Mediated Apoptosis.

Published in:

Cancers, 2021, v. 13, n. 11, p. 2740, doi. 10.3390/cancers13112740

By:

Tao, Rong-Hua;
Kobayashi, Masato;
Yang, Yuanzheng;
Kleinerman, Eugenie S.

Publication type:

Article

Neuronal Repressor REST Controls Ewing Sarcoma Growth and Metastasis by Affecting Vascular Pericyte Coverage and Vessel Perfusion.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1405, doi. 10.3390/cancers12061405

By:

Zhou, Zhichao;
Yang, Yuanzheng;
Wang, Fei;
Kleinerman, Eugenie S.

Publication type:

Article

Adenovirus-E1A gene therapy enhances the in vivo sensitivity of Ewing's sarcoma to VP-16.

Published in:

Cancer Gene Therapy, 2002, v. 9, n. 5, p. 407, doi. 10.1038/sj.cgt.7700449

By:

Zhou, Rong-Rong;
Jia, Shu-Fang;
Zhou, Zhichao;
Wang, Yunfang;
Bucana, Corazon D;
Kleinerman, Eugenie S

Publication type:

Article

Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector.

Published in:

Cancer Gene Therapy, 2002, v. 9, n. 3, p. 260, doi. 10.1038/sj.cgt.7700432

By:

Jia, Shu-Fang;
Worth, Laura L;
Densmore, Charles L;
Xu, Bo;
Zhou, Zhichao;
Kleinerman, Eugenie S

Publication type:

Article

Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI– p53 complexes.

Published in:

Cancer Gene Therapy, 2001, v. 8, n. 9, p. 619, doi. 10.1038/sj.cgt.7700343

By:

Densmore, Charles L;
Kleinerman, Eugenie S;
Gautam, Ajay;
Jia, Shu-Fang;
Xu, Bo;
Worth, Laura L;
Waldrep, J Clifford;
Fung, Yuen-Kai;
T'Ang, Anne;
Knight, Vernon

Publication type:

Article

Early skeletal muscle loss in adolescent and young adult cancer patients treated with anthracycline chemotherapy.

Published in:

Cancer Medicine, 2023, v. 12, n. 22, p. 20798, doi. 10.1002/cam4.6646

By:

Wooten, Savannah V.;
Wang, Fei;
Roth, Michael E.;
Liu, Guanshu;
Livingston, J. Andrew;
Amini, Behrang;
Gilchrist, Susan C.;
Hildebrandt, Michelle;
Kleinerman, Eugenie S.

Publication type:

Article

Exercise intervention decreases acute and late doxorubicin‐induced cardiotoxicity.

Published in:

Cancer Medicine, 2021, v. 10, n. 21, p. 7572, doi. 10.1002/cam4.4283

By:

Wang, Fei;
Chandra, Joya;
Kleinerman, Eugenie S.

Publication type:

Article

Anti‐PD‐1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases.

Published in:

Cancer Medicine, 2018, v. 7, n. 6, p. 2654, doi. 10.1002/cam4.1518

By:

Dhupkar, Pooja;
Gordon, Nancy;
Stewart, John;
Kleinerman, Eugenie S.

Publication type:

Article

Bempegaldesleukin (BEMPEG; NKTR‐214) efficacy as a single agent and in combination with checkpoint‐inhibitor therapy in mouse models of osteosarcoma.

Published in:

International Journal of Cancer, 2021, v. 148, n. 8, p. 1928, doi. 10.1002/ijc.33382

By:

Hennessy, Marlene;
Wahba, Andrew;
Felix, Kumar;
Cabrera, Mariella;
Segura, Maria Gabriela;
Kundra, Vikas;
Ravoori, Murali K.;
Stewart, John;
Kleinerman, Eugenie S.;
Jensen, Vanessa Behrana;
Gopalakrishnan, Vidya;
Pena, Rhoneil;
Quach, Phi;
Kim, Grace;
Kivimäe, Saul;
Madakamutil, Loui;
Overwijk, Willem W.;
Zalevsky, Jonathan;
Gordon, Nancy

Publication type:

Article

CD8+T cell-specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8+T cell accumulation in tumors.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-34

By:

Jiemiao Hu;
Shiguo Zhu;
Xueqing Xia;
Liangfang Liang;
Kleinerman, Eugenie S.;
Shulin Li

Publication type:

Article

Intravenous administration of the conditionally replicative adenovirus Ad5-Δ24RGD induces regression of osteosarcoma lung metastases.

Published in:

Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-9

By:

Graat, Harm C. A.;
van Beusechem, Victor W.;
Schagen, Frederik H. E.;
Witlox, M. Adhiambo;
Kleinerman, Eugenie S.;
Helder, Marco N.;
Gerritsen, Winald R.;
Kaspers, Gertjan J. L.;
Wuisman, Paul I. J. M.

Publication type:

Article

9-Nitrocamptothecin Liposome Aerosol Treatment of Human Cancer Subcutaneous Xenografts and Pulmonary Cancer Metastases in Mice.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 922, n. 1, p. 151, doi. 10.1111/j.1749-6632.2000.tb07033.x

By:

KNIGHT, VERNON;
KLEINERMAN, EUGENIE S.;
WALDREP, J. CLIFFORD;
GIOVANELLA, BEPPINO C.;
GILBERT, BRIAN E.;
KOSHKINA, NADEZHDA V.

Publication type:

Article

Interferon Gamma Induces Changes in Natural Killer (NK) Cell Ligand Expression and Alters NK Cell-Mediated Lysis of Pediatric Cancer Cell Lines.

Published in:

Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00391

By:

Aquino-López, Arianexys;
Senyukov, Vladimir V.;
Vlasic, Zlatko;
Kleinerman, Eugenie S.;
Lee, Dean A.

Publication type:

Article

The Innate Immune System in Cardiovascular Diseases and Its Role in Doxorubicin-Induced Cardiotoxicity.

Published in:

2022

By:

Bhagat, Anchit;
Shrestha, Pradeep;
Kleinerman, Eugenie S.

Publication type:

Literature Review

Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.947604

By:

Bhagat, Anchit;
Shrestha, Pradeep;
Jeyabal, Prince;
Zhanglong Peng;
Watowich, Stephanie S.;
Kleinerman, Eugenie S.

Publication type:

Article

Production of VEGF165 by Ewing's sarcoma cells induces vasculogenesis and the incorporation of CD34.

Published in:

International Journal of Cancer, 2006, v. 119, n. 4, p. 839, doi. 10.1002/ijc.21916

By:

Lee, Tim H.;
Bolontrade, Marcela F.;
Worth, Laura L.;
Guan, Hui;
Ellis, Lee M.;
Kleinerman, Eugenie S.

Publication type:

Article

Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases.

Published in:

International Journal of Cancer, 2005, v. 116, n. 3, p. 458, doi. 10.1002/ijc.21011

By:

Koshkina, Nadezhda V.;
Kleinerman, Eugenie S.

Publication type:

Article