Works by Klein-Hitpass, Ludger

Results: 77

Identification of Potent Ras Signaling Inhibitors by Pathway-Selective Phenotype-Based Screening (We thank Alfred Wittinghofer for his support. This study was supported by the Fonds der Chemischen Industrie and the European Union (Marie Curie Fellowship to M.C.).)

Published in:

Angewandte Chemie, 2004, v. 116, n. 4, p. 456, doi. 10.1002/ange.200352587

By:

Oliver Müller;
Eleni Gourzoulidou;
Mercedes Carpintero;
Ioanna-Maria Karaguni;
Anette Langerak;
Christian Herrmann;
Tarik Möröy;
Ludger Klein-Hitpaß;
Herbert Waldmann

Publication type:

Article

INTERFERENCE OF PERITONEAL DIALYSIS FLUIDS WITH CELL CYCLE MECHANISMS.

Published in:

Peritoneal Dialysis International, 2015, v. 35, n. 3, p. 259, doi. 10.3747/pdi.2013.00010

By:

Büchel, Janine;
Bartosova, Maria;
Eich, Gwendolyn;
Wittenberger, Timo;
Klein-Hitpass, Ludger;
Steppan, Sonja;
Hackert, Thilo;
Schaefer, Franz;
Passlick-Deetjen, Jutta;
Schmitt, Claus P.

Publication type:

Article

Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1227191

By:

Zec, Kristina;
Thiebes, Stephanie;
Bottek, Jenny;
Siemes, Devon;
Spangenberg, Philippa;
Trieu, Duc Viet;
Kirstein, Nils;
Subramaniam, Nirojah;
Christ, Robin;
Klein, Diana;
Jendrossek, Verena;
Loose, Maria;
Wagenlehner, Florian;
Jablonska, Jadwiga;
Bracht, Thilo;
Sitek, Barbara;
Budeus, Bettina;
Klein-Hitpass, Ludger;
Theegarten, Dirk;
Shevchuk, Olga

Publication type:

Article

Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function.

Published in:

Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0144-2

By:

Schröder, Christopher;
Leitão, Elsa;
Wallner, Stefan;
Schmitz, Gerd;
Klein-Hitpass, Ludger;
Sinha, Anupam;
Jöckel, Kar-Heinz;
Heilmann-Heimbach, Stefanie;
Hoffmann, Per;
Nöthen, Markus M.;
Steffens, Michael;
Ebert, Peter;
Rahmann, Sven;
Horsthemke, Bernhard

Publication type:

Article

Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia.

Published in:

European Journal of Haematology, 2009, v. 83, n. 4, p. 320, doi. 10.1111/j.1600-0609.2009.01287.x

By:

Eisele, Lewin;
Prinz, Robert;
Klein-Hitpass, Ludger;
Nückel, Holger;
Lowinski, Kerstin;
Thomale, Jürgen;
Moeller, Lars C.;
Dührsen, Ulrich;
Dürig, Jan

Publication type:

Article

Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemia.

Published in:

International Journal of Hematology, 2015, v. 102, n. 3, p. 278, doi. 10.1007/s12185-015-1833-x

By:

Li, Yu;
Dürig, Jan;
Göbel, Maria;
Hanoun, Maher;
Klein-Hitpaß, Ludger;
Dührsen, Ulrich

Publication type:

Article

Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells.

Published in:

2008

By:

Koldehoff, Michael;
Zakrzewski, Johannes;
Klein-Hitpass, Ludger;
Beelen, Dietrich;
Elmaagacli, Ahmet;
Zakrzewski, Johannes L;
Beelen, Dietrich W;
Elmaagacli, Ahmet H

Publication type:

journal article

Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2′-deoxycytidine.

Published in:

Clinical & Experimental Metastasis, 2004, v. 21, n. 5, p. 389, doi. 10.1007/s10585-005-1043-7

By:

Chen, Jie;
Röcken, Christoph;
Klein-Hitpass, Ludger;
Götze, Tobias;
Leodolter, Andreas;
Malfertheiner, Peter;
Ebert, Matthias

Publication type:

Article

A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, p. N.PAG, doi. 10.3389/fcimb.2021.639620

By:

Lauer, Alexa N.;
Scholtysik, Rene;
Beineke, Andreas;
Baums, Christoph Georg;
Klose, Kristin;
Valentin-Weigand, Peter;
Ishikawa, Hiroshi;
Schroten, Horst;
Klein-Hitpass, Ludger;
Schwerk, Christian

Publication type:

Article

Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 1, p. 65, doi. 10.1093/nar/gkr649

By:

Heise, Franziska;
Ho-Ryun Chung;
Weber, Jan M.;
Zhenyu Xu;
Klein-Hitpass, Ludger;
Steinmetz, Lars M.;
Vingron, Martin;
Ehrenhofer-Murray, Ann E.

Publication type:

Article

Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 19, p. e150, doi. 10.1093/nar/gnh144

By:

Thomas, Heike;
Senkel, Sabine;
Erdmann, Silke;
Arndt, Tanja;
Turan, Gülüzar;
Klein-Hitpass, Ludger;
Ryffel, Gerhart U.

Publication type:

Article

Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemia.

Published in:

Leukemia & Lymphoma, 2006, v. 47, n. 6, p. 1053, doi. 10.1080/10428190500464161

By:

Nückel, Holger;
Hüttmann, Andreas;
Klein-Hitpass, Ludger;
Schroers, Roland;
Führer, Anja;
Sellmann, Ludger;
Dührsen, Ulrich;
Dürig, Jan

Publication type:

Article

FTO levels affect RNA modification and the transcriptome.

Published in:

European Journal of Human Genetics, 2013, v. 21, n. 3, p. 317, doi. 10.1038/ejhg.2012.168

By:

Berulava, Tea;
Ziehe, Matthias;
Klein-Hitpass, Ludger;
Mladenov, Emil;
Thomale, Jürgen;
Rüther, Ulrich;
Horsthemke, Bernhard

Publication type:

Article

Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions.

Published in:

European Journal of Human Genetics, 2011, v. 19, n. 9, p. 947, doi. 10.1038/ejhg.2011.58

By:

Mitter, Diana;
Ullmann, Reinhard;
Muradyan, Artur;
Klein-Hitpaß, Ludger;
Kanber, Deniz;
Õunap, Katrin;
Kaulisch, Marc;
Lohmann, Dietmar

Publication type:

Article

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.

Published in:

Nature Genetics, 2012, v. 44, n. 11, p. 1199, doi. 10.1038/ng.2436

By:

Molenaar, Jan J;
Domingo-Fernández, Raquel;
Ebus, Marli E;
Lindner, Sven;
Koster, Jan;
Drabek, Ksenija;
Mestdagh, Pieter;
van Sluis, Peter;
Valentijn, Linda J;
van Nes, Johan;
Broekmans, Marloes;
Haneveld, Franciska;
Volckmann, Richard;
Bray, Isabella;
Heukamp, Lukas;
Sprüssel, Annika;
Thor, Theresa;
Kieckbusch, Kristina;
Klein-Hitpass, Ludger;
Fischer, Matthias

Publication type:

Article

Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation.

Published in:

FEBS Journal, 2005, v. 272, n. 7, p. 1600, doi. 10.1111/j.1742-4658.2005.04581.x

By:

Ziegler, Slava;
Röhrs, Sonja;
Tickenbrock, Lara;
Möröy, Tarik;
Klein-Hitpass, Ludger;
Vetter, Ingrid R.;
Müller, Oliver

Publication type:

Article

Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma.

Published in:

2016

By:

Naschberger, Elisabeth;
Liebl, Andrea;
Schellerer, Vera S.;
Schütz, Manuela;
Britzen-Laurent, Nathalie;
Kölbel, Patrick;
Schaal, Ute;
Haep, Lisa;
Regensburger, Daniela;
Wittmann, Thomas;
Klein-Hitpass, Ludger;
Rau, Tilman T.;
Dietel, Barbara;
Méniel, Valérie S.;
Clarke, Alan R.;
Merkel, Susanne;
Croner, Roland S.;
Hohenberger, Werner;
Stürzl, Michael

Publication type:

journal article

HNF4α orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells.

Published in:

Biological Chemistry, 2008, v. 389, n. 2, p. 179, doi. 10.1515/BC.2008.011

By:

Grigo, Karen;
Wirsing, Andrea;
Lucas, Belén;
Klein-Hitpass, Ludger;
Ryffel, Gerhart U.

Publication type:

Article

Tissue-specific transcription factor HNF4? inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 ?-cell line.

Published in:

Biological Chemistry, 2007, v. 388, n. 1, p. 91, doi. 10.1515/BC.2007.011

By:

Erdmann, Silke;
Senkel, Sabine;
Arndt, Tanja;
Lucas, Belén;
Lausen, Jörn;
Klein-Hitpass, Ludger;
Ryffel, Gerhart U.;
Thomas, Heike

Publication type:

Article

Pro-apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells.

Published in:

International Journal of Oncology, 2015, v. 46, n. 4, p. 1629, doi. 10.3892/ijo.2015.2854

By:

HARATI, KAMRAN;
SLODNIK, PAWEL;
CHROMIK, ANSGAR MICHAEL;
BEHR, BJÖRN;
GOERTZ, OLE;
HIRSCH, TOBIAS;
KAPALSCHINSKI, NICOLAI;
KLEIN-HITPASS, LUDGER;
KOLBENSCHLAG, JONAS;
UHL, WALDEMAR;
LEHNHARDT, MARCUS;
DAIGELER, ADRIEN

Publication type:

Article

Mesenchymal Stem Cells Isolated from the Anterior Cruciate Ligament: Characterization and Comparison of Cells from Young and Old Donors.

Published in:

Knee Surgery & Related Research, 2018, v. 30, n. 3, p. 193, doi. 10.5792/ksrr.17.067

By:

Prager, Patrick;
Kunz, Manuela;
Ebert, Regina;
Klein-Hitpass, Ludger;
Sieker, Jakob;
Barthel, Thomas;
Jakob, Franz;
Konrads, Christian;
Steinert, Andre

Publication type:

Article

Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia.

Published in:

Leukemia & Lymphoma, 2016, v. 57, n. 3, p. 590, doi. 10.3109/10428194.2015.1076929

By:

Sellmann, Ludger;
Scholtysik, Rene;
de Beer, Dirk;
Eisele, Lewin;
Klein-Hitpass, Ludger;
Nückel, Holger;
Dührsen, Ulrich;
Dürig, Jan;
Röth, Alexander;
Baerlocher, Gabriela M.

Publication type:

Article

Evolutionary Origin and Methylation Status of Human Intronic CpG Islands that Are Not Present in Mouse.

Published in:

Genome Biology & Evolution, 2014, v. 6, n. 7, p. 1579, doi. 10.1093/gbe/evu125

By:

Rademacher, Katrin;
Schröder, Christopher;
Kanber, Deniz;
Klein-Hitpass, Ludger;
Wallner, Stefan;
Zeschnigk, Michael;
Horsthemke, Bernhard

Publication type:

Article

Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3.

Published in:

Nature Genetics, 2013, v. 45, n. 8, p. 933, doi. 10.1038/ng.2674

By:

Martin, Marcel;
Maßhöfer, Lars;
Temming, Petra;
Rahmann, Sven;
Metz, Claudia;
Bornfeld, Norbert;
van de Nes, Johannes;
Klein-Hitpass, Ludger;
Hinnebusch, Alan G;
Horsthemke, Bernhard;
Lohmann, Dietmar R;
Zeschnigk, Michael

Publication type:

Article

Genome-Wide Analysis of the Nucleosome Landscape in Individuals with Coffin-Siris Syndrome.

Published in:

Cytogenetic & Genome Research, 2019, v. 159, n. 1, p. 1, doi. 10.1159/000503266

By:

Kalmbach, alexander;
Schröder, Christopher;
Klein-Hitpass, Ludger;
Nordström, Karl;
Ulz, Peter;
Heitzer, Ellen;
Speicher, Michael R.;
Rahmann, Sven;
Wieczorek, Dagmar;
Horsthemke, Bernhard;
Bramswig, Nuria C.

Publication type:

Article

Somatic mosaicism for maternal uniparental disomy 15 in a girl with Prader–Willi syndrome: confirmation by cell cloning and identification of candidate downstream genes.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 20, p. 2723, doi. 10.1093/hmg/ddg291

By:

Horsthemke, Bernhard;
Nazlican, Hülya;
Hüsing, Johannes;
Klein-Hitpaß, Ludger;
Claussen, Uwe;
Michel, Susanne;
Lich, Christina;
Gillessen-Kaesbach, Gabriele;
Buiting, Karin

Publication type:

Article

Characterization of bursa subacromialis-derived mesenchymal stem cells.

Published in:

Stem Cell Research & Therapy, 2015, v. 6, n. 1, p. 1, doi. 10.1186/s13287-015-0104-3

By:

Steinert, Andre F.;
Kunz, Manuela;
Prager, Patrick;
Göbel, Sascha;
Klein-Hitpass, Ludger;
Ebert, Regina;
Nöth, Ulrich;
Jakob, Franz;
Gohlke, Frank

Publication type:

Article

Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy.

Published in:

Breast Cancer Research & Treatment, 2010, v. 118, n. 1, p. 45, doi. 10.1007/s10549-008-0207-y

By:

Specht, Katja;
Harbeck, Nadia;
Smida, Jan;
Annecke, Katja;
Reich, Ulrike;
Naehrig, Joerg;
Langer, Rupert;
Mages, Joerg;
Busch, Raymonde;
Kruse, Elisabeth;
Klein-Hitpass, Ludger;
Schmitt, Manfred;
Kiechle, Marion;
Hoefler, Heinz

Publication type:

Article

Microarray analyses of transdifferentiated mesenchymal stem cells.

Published in:

Journal of Cellular Biochemistry, 2008, v. 103, n. 2, p. 413, doi. 10.1002/jcb.21415

By:

Schilling, Tatjana;
Küffner, Robert;
Klein-Hitpass, Ludger;
Zimmer, Ralf;
Jakob, Franz;
Schütze, Norbert

Publication type:

Article

Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing.

Published in:

Cancers, 2020, v. 12, n. 4, p. 986, doi. 10.3390/cancers12040986

By:

Johansson, Patricia;
Klein-Hitpass, Ludger;
Budeus, Bettina;
Kuhn, Matthias;
Lauber, Chris;
Seifert, Michael;
Roeder, Ingo;
Pförtner, Roman;
Stuschke, Martin;
Dührsen, Ulrich;
Eckstein, Anja;
Dürig, Jan;
Küppers, Ralf

Publication type:

Article

The Survivin Isoform Survivin-3B is Cytoprotective and Can Function as a Chromosomal Passenger Complex Protein.

Published in:

Cell Cycle, 2007, v. 6, n. 12, p. 1502, doi. 10.4161/cc.6.12.4305

By:

Knauer, Shirley K.;
Bier, Carolin;
Schlag, Peter;
Fritzmann, Johannes;
Dietmaier, Wolfgang;
Rödel, Franz;
Klein-Hitpass, Ludger;
Kovács, Adoriàn F.;
Döring, Claudia;
Hansmann, Martin-Leo;
Hofmann, Wolf-Karsten;
Kunkel, Martin;
Brochhausen, Christoph;
Engels, Knut;
Lippert, Burkhard M.;
Mann, Wolf;
Stauber, Roland H.

Publication type:

Article

NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells.

Published in:

Radiation Research, 2025, v. 203, n. 1, p. 37, doi. 10.1667/RADE-24-00094.1

By:

Soni, Aashish;
Beisser, Daniela;
Mladenov, Emil;
Höller, Matthias;
Wohlers, Inken;
Nikolov, Vladimir;
Magin, Simon;
Mussfeldt, Tamara;
Klein-Hitpass, Ludger;
Cornforth, Michael N.;
Loucas, Bradford D.;
Rahmann, Sven;
Iliakis, George

Publication type:

Article

Depletion of Foxp3<sup>+</sup> regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome.

Published in:

Immunology, 2020, v. 159, n. 3, p. 344, doi. 10.1111/imm.13158

By:

Kehrmann, Jan;
Effenberg, Laura;
Wilk, Camilla;
Schoemer, Davina;
Ngo Thi Phuong, Nhi;
Adamczyk, Alexandra;
Pastille, Eva;
Scholtysik, René;
Klein‐Hitpass, Ludger;
Klopfleisch, Robert;
Westendorf, Astrid M.;
Buer, Jan

Publication type:

Article

Induction of Inflammatory Cytokines by a Keratin Mutation and their Repression by a Small Molecule in a Mouse Model for EBS.

Published in:

Journal of Investigative Dermatology, 2007, v. 127, n. 12, p. 2781, doi. 10.1038/sj.jid.5700918

By:

Hong Lu;
Jian Chen;
Planko, Laura;
Zigrino, Paola;
Klein-Hitpass, Ludger;
Magin, Thomas M.

Publication type:

Article

Altering gene expression by aminocoumarins: the role of DNA supercoiling in Staphylococcus aureus.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-291

By:

Schröder, Wiebke;
Bernhardt, Jörg;
Marincola, Gabriella;
Klein-Hitpass, Ludger;
Herbig, Alexander;
Krupp, Guido;
Nieselt, Kay;
Wolz, Christiane

Publication type:

Article

SMAF-1 Inhibits the APC/β-Catenin Pathway and Shows Properties Similar to Those of the Tumor Suppressor Protein APC.

Published in:

ChemBioChem, 2004, v. 5, n. 9, p. 1267, doi. 10.1002/cbic.200400078

By:

Ioanna-Maria Karaguni;
Eleni Gourzoulidou;
Mercedes Carpintero;
Anette Langerak;
Ludger Klein-Hitpaß;
Tarik Möröy;
Günther Winde;
Herbert Waldmann;
Oliver Müller

Publication type:

Article

microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 10, p. 1953, doi. 10.1007/s00424-013-1429-3

By:

Baars, Theodor;
Skyschally, Andreas;
Klein-Hitpass, Ludger;
Cario, Elke;
Erbel, Raimund;
Heusch, Gerd;
Kleinbongard, Petra

Publication type:

Article

Common denominator genes that distinguish colorectal carcinoma from normal mucosa.

Published in:

International Journal of Colorectal Disease, 2005, v. 20, n. 4, p. 353, doi. 10.1007/s00384-004-0664-7

By:

Croner, Roland S.;
Foertsch, Thomas;
Brueckl, Wolfgang M.;
Guenther, Klaus;
Siebenhaar, Renate;
Stremmel, Christian;
Matzel, Klaus E.;
Papadopoulos, Thomas;
Kirchner, Thomas;
Behrens, Jürgen;
Klein-Hitpass, Ludger;
Stuerzl, Michael;
Hohenberger, Werner;
Reingruber, Bertram

Publication type:

Article

Expanded CD8 T cells of murine and human CLL are driven into a senescent KLRG1 effector memory phenotype.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 11, p. 1697, doi. 10.1007/s00262-013-1473-z

By:

Göthert, Joachim;
Eisele, Lewin;
Klein-Hitpass, Ludger;
Weber, Stefanie;
Zesewitz, Marie-Louise;
Sellmann, Ludger;
Röth, Alexander;
Pircher, Hanspeter;
Dührsen, Ulrich;
Dürig, Jan

Publication type:

Article

Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration.

Published in:

Aging Cell, 2013, v. 12, n. 6, p. 988, doi. 10.1111/acel.12124

By:

Kohler, Julia;
Popov, Cvetan;
Klotz, Barbara;
Alberton, Paolo;
Prall, Wolf Christian;
Haasters, Florian;
Müller‐Deubert, Sigrid;
Ebert, Regina;
Klein‐Hitpass, Ludger;
Jakob, Franz;
Schieker, Matthias;
Docheva, Denitsa

Publication type:

Article

Recurrent alterations of TNFAIP 3 ( A20) in T-cell large granular lymphocytic leukemia.

Published in:

International Journal of Cancer, 2016, v. 138, n. 1, p. 121, doi. 10.1002/ijc.29697

By:

Johansson, Patricia;
Bergmann, Anke;
Rahmann, Sven;
Wohlers, Inken;
Scholtysik, René;
Przekopowitz, Martina;
Seifert, Marc;
Tschurtschenthaler, Gertraud;
Webersinke, Gerald;
Jäger, Ulrich;
Siebert, Reiner;
Klein ‐ Hitpass, Ludger;
Dührsen, Ulrich;
Dürig, Jan;
Küppers, Ralf

Publication type:

Article

MYCN regulates oncogenic MicroRNAs in neuroblastoma.

Published in:

International Journal of Cancer, 2008, v. 122, n. 3, p. 699, doi. 10.1002/ijc.23153

By:

Schulte, Johannes H.;
Horn, Sebastian;
Otto, Tobias;
Samans, Birgit;
Heukamp, Lukas C.;
Eilers, Ursula-Christa;
Krause, Michael;
Astrahantseff, Kathy;
Klein-Hitpass, Ludger;
Buettner, Reinhard;
Schramm, Alexander;
Christiansen, Holger;
Eilers, Martin;
Eggert, Angelika;
Berwanger, Bernd

Publication type:

Article

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15440, doi. 10.1038/ncomms15440

By:

Sucker, Antje;
Zhao, Fang;
Pieper, Natalia;
Heeke, Christina;
Maltaner, Raffaela;
Stadtler, Nadine;
Real, Birgit;
Bielefeld, Nicola;
Howe, Sebastian;
Weide, Benjamin;
Gutzmer, Ralf;
Utikal, Jochen;
Loquai, Carmen;
Gogas, Helen;
Klein-Hitpass, Ludger;
Zeschnigk, Michael;
Westendorf, Astrid M.;
Trilling, Mirko;
Horn, Susanne;
Schilling, Bastian

Publication type:

Article

Identification of Potent Ras Signaling Inhibitors by Pathway-Selective Phenotype-Based Screening (We thank Alfred Wittinghofer for his support. This study was supported by the Fonds der Chemischen Industrie and the European Union (Marie Curie Fellowship to M.C.).)

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 4, p. 450, doi. 10.1002/anie.200352587

By:

Oliver Müller;
Eleni Gourzoulidou;
Mercedes Carpintero;
Ioanna-Maria Karaguni;
Anette Langerak;
Christian Herrmann;
Tarik Möröy;
Ludger Klein-Hitpaß;
Herbert Waldmann

Publication type:

Article

CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 3, p. 405, doi. 10.1007/s00401-020-02169-z

By:

Jünger, Stephanie T.;
Andreiuolo, Felipe;
Mynarek, Martin;
Wohlers, Inken;
Rahmann, Sven;
Klein-Hitpass, Ludger;
Dörner, Evelyn;
zur Mühlen, Anja;
Velez-Char, Natalia;
von Hoff, Katja;
Warmuth-Metz, Monika;
Kortmann, Rolf-Dieter;
Timmermann, Beate;
von Bueren, Andre;
Rutkowski, Stefan;
Pietsch, Torsten

Publication type:

Article

Supratentorial ependymomas of childhood carry C11orf95- RELA fusions leading to pathological activation of the NF-κB signaling pathway.

Published in:

2014

By:

Pietsch, Torsten;
Wohlers, Inken;
Goschzik, Tobias;
Dreschmann, Verena;
Denkhaus, Dorota;
Dörner, Evelyn;
Rahmann, Sven;
Klein-Hitpass, Ludger

Publication type:

Letter

Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06069-5

By:

Mangolini, Maurizio;
Götte, Frederik;
Moore, Andrew;
Ammon, Tim;
Oelsner, Madlen;
Lutzny-Geier, Gloria;
Klein-Hitpass, Ludger;
Williamson, James C.;
Lehner, Paul J.;
Dürig, Jan;
Möllmann, Michael;
Rásó-Barnett, Lívia;
Hughes, Katherine;
Santoro, Antonella;
Méndez-Ferrer, Simón;
Oostendorp, Robert A. J.;
Zimber-Strobl, Ursula;
Peschel, Christian;
Hodson, Daniel J.;
Schmidt-Supprian, Marc

Publication type:

Article

Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease.

Published in:

2019

By:

Kehrmann, Jan;
Menzel, Jannis;
Saeedghalati, Mohammadkarim;
Obeid, Rima;
Schulze, Christina;
Holzendorf, Volker;
Farahpour, Farnoush;
Reinsch, Nico;
Klein-Hitpass, Ludger;
Streeck, Handrik;
Hoffmann, Daniel;
Buer, Jan;
Esser, Stefan;
Group, HIV-HEART Study;
HIV-HEART Study Group

Publication type:

journal article

Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells.

Published in:

EMBO Journal, 2004, v. 23, n. 20, p. 4116, doi. 10.1038/sj.emboj.7600419

By:

Zeng, Hui;
Yücel, Raif;
Kosan, Christian;
Klein-Hitpass, Ludger;
Möröy, Tarik

Publication type:

Article

Nuclear export is essential for the tumor-promoting activity of survivin.

Published in:

FASEB Journal, 2007, v. 21, n. 1, p. 207, doi. 10.1096/fj.06-5741com

By:

Knauer, Shirley K.;
Krämer, Oliver H.;
Knösel, Thomas;
Engels, Knut;
Rödel, Franz;
Kovács, Adorján F.;
Dietmaier, Wofgang;
Klein-Hitpass, Ludger;
Habtemichael, Negusse;
Schweitzer, Andrea;
Brieger, Jürgen;
Rödel, Claus;
Mann, Wolf;
Peterson, Iver;
Heinzel, Thorsten;
Stauber, Roland H.

Publication type:

Article