Works by Klarin, Derek

Results: 29

X‐linked genetic associations in sporadic thoracic aortic dissection.
Published in:
American Journal of Medical Genetics. Part A, 2024, v. 194, n. 9, p. 1, doi. 10.1002/ajmg.a.63644
By:
- Musfee, Fadi I.;
- Jun, Goo;
- Mitchell, Laura E.;
- Chen, Han;
- Guo, Dongchuan;
- Prakash, Siddharth K.;
- Adkar, Shaunak Sanjay;
- Grove, Megan L.;
- Choi, Ryan Bohyun;
- Klarin, Derek;
- Boerwinkle, Eric;
- Milewicz, Dianna M.
Publication type:
Article
Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits.
Published in:
Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00773-z
By:
- Bone, William P.;
- Siewert, Katherine M.;
- Jha, Anupama;
- Klarin, Derek;
- Damrauer, Scott M.;
- The VA Million Veteran Program;
- Ballas, Zuhair K.;
- Bhushan, Sujata;
- Boyko, Edward J.;
- Cohen, David M.;
- Concato, John;
- Constans, Joseph I.;
- Dellitalia, Louis J.;
- Fayad, Joseph M.;
- Fernando, Ronald S.;
- Florez, Hermes J.;
- Gaddy, Melinda A.;
- Gappy, Saib S.;
- Gibson, Gretchen;
- Godschalk, Michael
Publication type:
Article
Genetic predisposition to smoking in relation to 14 cardiovascular diseases.
Published in:
European Heart Journal, 2020, v. 41, n. 35, p. 3304, doi. 10.1093/eurheartj/ehaa193
By:
- Larsson, Susanna C;
- Mason, Amy M;
- Bäck, Magnus;
- Klarin, Derek;
- Damrauer, Scott M;
- Program, Million Veteran;
- Michaëlsson, Karl;
- Burgess, Stephen
Publication type:
Article
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins.
Published in:
PLoS Genetics, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pgen.1009802
By:
- Khetarpal, Sumeet A.;
- Vitali, Cecilia;
- Levin, Michael G.;
- Klarin, Derek;
- Park, Joseph;
- Pampana, Akhil;
- Millar, John S.;
- Kuwano, Takashi;
- Sugasini, Dhavamani;
- Subbaiah, Papasani V.;
- Billheimer, Jeffrey T.;
- Natarajan, Pradeep;
- Rader, Daniel J.
Publication type:
Article
The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.
Published in:
2020
By:
- Johnson, Kelsey E.;
- Siewert, Katherine M.;
- Klarin, Derek;
- Damrauer, Scott M.;
- Chang, Kyong-Mi;
- Tsao, Philip S.;
- Assimes, Themistocles L.;
- Maxwell, Kara N.;
- Voight, Benjamin F.;
- VA Million Veteran Program
Publication type:
journal article
Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35.
Published in:
Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1181167
By:
- Cullina, Sinead;
- Wojcik, Genevieve L.;
- Shemirani, Ruhollah;
- Klarin, Derek;
- Gorman, Bryan R.;
- Sorokin, Elena P.;
- Gignoux, Christopher R.;
- Belbin, Gillian M.;
- Pyarajan, Saiju;
- Asgari, Samira;
- Tsao, Philip S.;
- Damrauer, Scott M.;
- Abul-Husn, Noura S.;
- Kenny, Eimear E.
Publication type:
Article
Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease.
Published in:
2019
By:
- Honigberg, Michael C.;
- Zekavat, Seyedeh Maryam;
- Aragam, Krishna;
- Finneran, Phoebe;
- Klarin, Derek;
- Bhatt, Deepak L.;
- Januzzi, James L.;
- Scott, Nandita S.;
- Natarajan, Pradeep;
- Januzzi, James L Jr
Publication type:
journal article
Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease.
Published in:
2017
By:
- Emdin, Connor A.;
- Khera, Amit V.;
- Natarajan, Pradeep;
- Klarin, Derek;
- Zekavat, Seyedeh M.;
- Hsiao, Allan J.;
- Kathiresan, Sekar
Publication type:
journal article
Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study.
Published in:
JAMA Network Open, 2021, v. 4, n. 1, p. 1, doi. 10.1001/jamanetworkopen.2020.34461
By:
- Levin, Michael G.;
- Klarin, Derek;
- Assimes, Themistocles L.;
- Freiberg, Matthew S.;
- Ingelsson, Erik;
- Lynch, Julie;
- Natarajan, Pradeep;
- O'Donnell, Christopher;
- Rader, Daniel J.;
- Tsao, Philip S.;
- Kyong-Mi Chang;
- Voight, Benjamin F.;
- Damrauer, Scott M.
Publication type:
Article
Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03911-8
By:
- Emdin, Connor A.;
- Khera, Amit V.;
- Chaffin, Mark;
- Klarin, Derek;
- Natarajan, Pradeep;
- Aragam, Krishna;
- Haas, Mary;
- Bick, Alexander;
- Zekavat, Seyedeh M.;
- Akihiro Nomura;
- Ardissino, Diego;
- Wilson, James G.;
- Schunkert, Heribert;
- McPherson, Ruth;
- Watkins, Hugh;
- Elosua, Roberto;
- Bown, Matthew J.;
- Samani, Nilesh J.;
- Baber, Usman;
- Erdmann, Jeanette
Publication type:
Article
PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.
Published in:
PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0239752
By:
- Small, Aeron M.;
- Huffman, Jennifer E.;
- Klarin, Derek;
- Lynch, Julie A.;
- Assimes, Themistocles;
- DuVall, Scott;
- Sun, Yan V.;
- Shere, Labiba;
- Natarajan, Pradeep;
- Gaziano, Michael;
- Rader, Daniel J.;
- Wilson, Peter W. F.;
- Tsao, Philip S.;
- Chang, Kyong-Mi;
- Cho, Kelly;
- O'Donnell, Christopher J.;
- Casas, Juan P.;
- Damrauer, Scott M.
Publication type:
Article
Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses.
Published in:
British Journal of Haematology, 2023, v. 201, n. 4, p. 783, doi. 10.1111/bjh.18679
By:
- Yuan, Shuai;
- Titova, Olga E.;
- Zhang, Ke;
- Gou, Wanglong;
- Schillemans, Tessa;
- Natarajan, Pradeep;
- Chen, Jie;
- Li, Xue;
- Åkesson, Agneta;
- Bruzelius, Maria;
- Klarin, Derek;
- Damrauer, Scott M.;
- Larsson, Susanna C.
Publication type:
Article
Gene-gene Interaction Analyses for Atrial Fibrillation.
Published in:
Scientific Reports, 2016, p. 35371, doi. 10.1038/srep35371
By:
- Lin, Honghuang;
- Mueller-Nurasyid, Martina;
- Smith, Albert V.;
- Arking, Dan E.;
- Barnard, John;
- Bartz, Traci M.;
- Lunetta, Kathryn L.;
- Lohman, Kurt;
- Kleber, Marcus E.;
- Lubitz, Steven A.;
- Geelhoed, Bastiaan;
- Trompet, Stella;
- Niemeijer, Maartje N.;
- Kacprowski, Tim;
- Chasman, Daniel I.;
- Klarin, Derek;
- Sinner, Moritz F.;
- Waldenberger, Melanie;
- Meitinger, Thomas;
- Harris, Tamara B.
Publication type:
Article
Erratum to: Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache.
Published in:
2020
By:
- Siewert, Katherine M;
- Klarin, Derek;
- Damrauer, Scott M;
- Chang, Kyong-Mi;
- Tsao, Philip S;
- Assimes, Themistocles L;
- Smith, George Davey;
- Voight, Benjamin F
Publication type:
journal article
Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache.
Published in:
2020
By:
- Siewert, Katherine M;
- Klarin, Derek;
- Damrauer, Scott M;
- Chang, Kyong-Mi;
- Tsao, Philip S;
- Assimes, Themistocles L;
- Smith, George Davey;
- Voight, Benjamin F;
- Davey Smith, George;
- The International Headache Genetics Consortium
Publication type:
journal article
Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.
Published in:
Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.787545
By:
- Bellomo, Tiffany R.;
- Bone, William P.;
- Chen, Brian Y.;
- Gawronski, Katerina A. B.;
- Zhang, David;
- Park, Joseph;
- Levin, Michael;
- Tsao, Noah;
- Klarin, Derek;
- Lynch, Julie;
- Assimes, Themistocles L.;
- Gaziano, J. Michael;
- Wilson, Peter W.;
- Cho, Kelly;
- Vujkovic, Marijana;
- the VA Million Veteran Program;
- O'Donnell, Christopher J.;
- Chang, Kyong-Mi;
- Tsao, Philip S.;
- Rader, Daniel J.
Publication type:
Article
Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
Published in:
2021
By:
- Emdin, Connor A.;
- Haas, Mary E.;
- Khera, Amit V.;
- Aragam, Krishna;
- Chaffin, Mark;
- Klarin, Derek;
- Hindy, George;
- Jiang, Lan;
- Wei, Wei-Qi;
- Feng, Qiping;
- Karjalainen, Juha;
- Havulinna, Aki;
- Kiiskinen, Tuomo;
- Bick, Alexander;
- Ardissino, Diego;
- Wilson, James G.;
- Schunkert, Heribert;
- McPherson, Ruth;
- Watkins, Hugh;
- Elosua, Roberto
Publication type:
Correction Notice
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
Published in:
PLoS Genetics, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.pgen.1008629
By:
- Emdin, Connor A.;
- Haas, Mary E.;
- Khera, Amit V.;
- Aragam, Krishna;
- Chaffin, Mark;
- Klarin, Derek;
- Hindy, George;
- Jiang, Lan;
- Wei, Wei-Qi;
- Feng, Qiping;
- Karjalainen, Juha;
- Havulinna, Aki;
- Kiiskinen, Tuomo;
- Bick, Alexander;
- Ardissino, Diego;
- Wilson, James G.;
- Schunkert, Heribert;
- McPherson, Ruth;
- Watkins, Hugh;
- Elosua, Roberto
Publication type:
Article
Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.
Published in:
PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008684
By:
- Hu, Yao;
- Graff, Mariaelisa;
- Haessler, Jeffrey;
- Buyske, Steven;
- Bien, Stephanie A.;
- Tao, Ran;
- Highland, Heather M.;
- Nishimura, Katherine K.;
- Zubair, Niha;
- Lu, Yingchang;
- Verbanck, Marie;
- Hilliard, Austin T.;
- Klarin, Derek;
- Damrauer, Scott M.;
- Ho, Yuk-Lam;
- Wilson, Peter W. F.;
- Chang, Kyong-Mi;
- Tsao, Philip S.;
- Cho, Kelly;
- O'Donnell, Christopher J.
Publication type:
Article
Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 20, p. 3566, doi. 10.1093/hmg/ddac051
By:
- Portilla-Fernandez, Eliana;
- Klarin, Derek;
- Hwang, Shih-Jen;
- Biggs, Mary L;
- Bis, Joshua C;
- Weiss, Stefan;
- Rospleszcz, Susanne;
- Natarajan, Pradeep;
- Hoffmann, Udo;
- Rogers, Ian S;
- Truong, Quynh A;
- Völker, Uwe;
- Dörr, Marcus;
- Bülow, Robin;
- Criqui, Michael H;
- Allison, Matthew;
- Ganesh, Santhi K;
- Yao, Jie;
- Waldenberger, Melanie;
- Bamberg, Fabian
Publication type:
Article
Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
Published in:
2019
By:
- Kranzler, Henry R.;
- Zhou, Hang;
- Kember, Rachel L.;
- Smith, Rachel Vickers;
- Justice, Amy C.;
- Damrauer, Scott;
- Tsao, Philip S.;
- Klarin, Derek;
- Baras, Aris;
- Reid, Jeffrey;
- Overton, John;
- Rader, Daniel J.;
- Cheng, Zhongshan;
- Tate, Janet P.;
- Becker, William C.;
- Concato, John;
- Xu, Ke;
- Polimanti, Renato;
- Zhao, Hongyu;
- Gelernter, Joel
Publication type:
Correction Notice
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11704-w
By:
- Hellwege, Jacklyn N.;
- Velez Edwards, Digna R.;
- Giri, Ayush;
- Qiu, Chengxiang;
- Park, Jihwan;
- Torstenson, Eric S.;
- Keaton, Jacob M.;
- Wilson, O. D.;
- Robinson-Cohen, Cassianne;
- Chung, Cecilia P.;
- Roumie, Christianne L.;
- Klarin, Derek;
- Damrauer, Scott M.;
- DuVall, Scott L.;
- Siew, Edward;
- Akwo, Elvis A.;
- Wuttke, Matthias;
- Gorski, Mathias;
- Li, Man;
- Li, Yong
Publication type:
Article
Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
Published in:
2019
By:
- Kranzler, Henry R.;
- Zhou, Hang;
- Kember, Rachel L.;
- Smith, Rachel Vickers;
- Justice, Amy C.;
- Damrauer, Scott;
- Tsao, Philip S.;
- Klarin, Derek;
- Baras, Aris;
- Reid, Jeffrey;
- Overton, John;
- Rader, Daniel J.;
- Cheng, Zhongshan;
- Tate, Janet P.;
- Becker, William C.;
- Concato, John;
- Xu, Ke;
- Polimanti, Renato;
- Zhao, Hongyu;
- Gelernter, Joel
Publication type:
Correction Notice
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09480-8
By:
- Kranzler, Henry R.;
- Zhou, Hang;
- Kember, Rachel L.;
- Vickers Smith, Rachel;
- Justice, Amy C.;
- Damrauer, Scott;
- Tsao, Philip S.;
- Klarin, Derek;
- Baras, Aris;
- Reid, Jeffrey;
- Overton, John;
- Rader, Daniel J.;
- Cheng, Zhongshan;
- Tate, Janet P.;
- Becker, William C.;
- Concato, John;
- Xu, Ke;
- Polimanti, Renato;
- Zhao, Hongyu;
- Gelernter, Joel
Publication type:
Article
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Published in:
Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02837-1
By:
- Kanoni, Stavroula;
- Graham, Sarah E.;
- Wang, Yuxuan;
- Surakka, Ida;
- Ramdas, Shweta;
- Zhu, Xiang;
- Clarke, Shoa L.;
- Bhatti, Konain Fatima;
- Vedantam, Sailaja;
- Winkler, Thomas W.;
- Locke, Adam E.;
- Marouli, Eirini;
- Zajac, Greg J. M.;
- Wu, Kuan-Han H.;
- Ntalla, Ioanna;
- Hui, Qin;
- Klarin, Derek;
- Hilliard, Austin T.;
- Wang, Zeyuan;
- Xue, Chao
Publication type:
Article
Circulating proteins and peripheral artery disease risk: observational and Mendelian randomization analyses.
Published in:
European Heart Journal Open, 2023, v. 3, n. 3, p. 1, doi. 10.1093/ehjopen/oead056
By:
- Yuan, Shuai;
- Titova, Olga E;
- Zhang, Ke;
- Chen, Jie;
- Li, Xue;
- Klarin, Derek;
- Åkesson, Agneta;
- Damrauer, Scott M;
- Larsson, Susanna C
Publication type:
Article
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors.
Published in:
Journal of the American Heart Association, 2024, v. 13, n. 4, p. 1, doi. 10.1161/JAHA.123.030233
By:
- Shakt, Gabrielle;
- Tsao, Noah L.;
- Levin, Michael G.;
- Walker, Venexia;
- Kember, Rachel L.;
- Klarin, Derek;
- Tsao, Phil;
- Voight, Benjamin F.;
- Scali, Salvatore T.;
- Damrauer, Scott M.
Publication type:
Article
DNA Sequence Variation in Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.
Published in:
2019
By:
- Emdin, Connor A.;
- Khera, Amit V.;
- Aragam, Krishna;
- Haas, Mary;
- Chaffin, Mark;
- Klarin, Derek;
- Natarajan, Pradeep;
- Bick, Alexander;
- Zekavat, Seyedeh M.;
- Akihiro Nomura;
- Ardissino, Diego;
- Wilson, James G.;
- Schunkert, Heribert;
- McPherson, Ruth;
- Watkins, Hugh;
- Elosua, Roberto;
- Bown, Matthew J.;
- Samani, Nilesh J.;
- Baber, Usman;
- Erdmann, Jeanette
Publication type:
journal article
Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease.
Published in:
2017
By:
- Emdin, Connor A.;
- Klarin, Derek;
- Natarajan, Pradeep;
- Florez, Jose C.;
- Kathiresan, Sekar;
- Khera, Amit V.;
- CARDIOGRAM Exome Consortium
Publication type:
journal article