Works matching AU Klarin, Derek

Results: 30
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    X‐linked genetic associations in sporadic thoracic aortic dissection.

    Published in:
    American Journal of Medical Genetics. Part A, 2024, v. 194, n. 9, p. 1, doi. 10.1002/ajmg.a.63644
    By:
    • Musfee, Fadi I.;
    • Jun, Goo;
    • Mitchell, Laura E.;
    • Chen, Han;
    • Guo, Dongchuan;
    • Prakash, Siddharth K.;
    • Adkar, Shaunak Sanjay;
    • Grove, Megan L.;
    • Choi, Ryan Bohyun;
    • Klarin, Derek;
    • Boerwinkle, Eric;
    • Milewicz, Dianna M.
    Publication type:
    Article
    4

    Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.

    Published in:
    Human Molecular Genetics, 2022, v. 31, n. 20, p. 3566, doi. 10.1093/hmg/ddac051
    By:
    • Portilla-Fernandez, Eliana;
    • Klarin, Derek;
    • Hwang, Shih-Jen;
    • Biggs, Mary L;
    • Bis, Joshua C;
    • Weiss, Stefan;
    • Rospleszcz, Susanne;
    • Natarajan, Pradeep;
    • Hoffmann, Udo;
    • Rogers, Ian S;
    • Truong, Quynh A;
    • Völker, Uwe;
    • Dörr, Marcus;
    • Bülow, Robin;
    • Criqui, Michael H;
    • Allison, Matthew;
    • Ganesh, Santhi K;
    • Yao, Jie;
    • Waldenberger, Melanie;
    • Bamberg, Fabian
    Publication type:
    Article
    5

    Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.

    Published in:
    Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.787545
    By:
    • Bellomo, Tiffany R.;
    • Bone, William P.;
    • Chen, Brian Y.;
    • Gawronski, Katerina A. B.;
    • Zhang, David;
    • Park, Joseph;
    • Levin, Michael;
    • Tsao, Noah;
    • Klarin, Derek;
    • Lynch, Julie;
    • Assimes, Themistocles L.;
    • Gaziano, J. Michael;
    • Wilson, Peter W.;
    • Cho, Kelly;
    • Vujkovic, Marijana;
    • the VA Million Veteran Program;
    • O'Donnell, Christopher J.;
    • Chang, Kyong-Mi;
    • Tsao, Philip S.;
    • Rader, Daniel J.
    Publication type:
    Article
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    Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins.

    Published in:
    PLoS Genetics, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pgen.1009802
    By:
    • Khetarpal, Sumeet A.;
    • Vitali, Cecilia;
    • Levin, Michael G.;
    • Klarin, Derek;
    • Park, Joseph;
    • Pampana, Akhil;
    • Millar, John S.;
    • Kuwano, Takashi;
    • Sugasini, Dhavamani;
    • Subbaiah, Papasani V.;
    • Billheimer, Jeffrey T.;
    • Natarajan, Pradeep;
    • Rader, Daniel J.
    Publication type:
    Article
    13

    Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03911-8
    By:
    • Emdin, Connor A.;
    • Khera, Amit V.;
    • Chaffin, Mark;
    • Klarin, Derek;
    • Natarajan, Pradeep;
    • Aragam, Krishna;
    • Haas, Mary;
    • Bick, Alexander;
    • Zekavat, Seyedeh M.;
    • Akihiro Nomura;
    • Ardissino, Diego;
    • Wilson, James G.;
    • Schunkert, Heribert;
    • McPherson, Ruth;
    • Watkins, Hugh;
    • Elosua, Roberto;
    • Bown, Matthew J.;
    • Samani, Nilesh J.;
    • Baber, Usman;
    • Erdmann, Jeanette
    Publication type:
    Article
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    A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

    Published in:
    PLoS Genetics, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.pgen.1008629
    By:
    • Emdin, Connor A.;
    • Haas, Mary E.;
    • Khera, Amit V.;
    • Aragam, Krishna;
    • Chaffin, Mark;
    • Klarin, Derek;
    • Hindy, George;
    • Jiang, Lan;
    • Wei, Wei-Qi;
    • Feng, Qiping;
    • Karjalainen, Juha;
    • Havulinna, Aki;
    • Kiiskinen, Tuomo;
    • Bick, Alexander;
    • Ardissino, Diego;
    • Wilson, James G.;
    • Schunkert, Heribert;
    • McPherson, Ruth;
    • Watkins, Hugh;
    • Elosua, Roberto
    Publication type:
    Article
    20

    Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.

    Published in:
    PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008684
    By:
    • Hu, Yao;
    • Graff, Mariaelisa;
    • Haessler, Jeffrey;
    • Buyske, Steven;
    • Bien, Stephanie A.;
    • Tao, Ran;
    • Highland, Heather M.;
    • Nishimura, Katherine K.;
    • Zubair, Niha;
    • Lu, Yingchang;
    • Verbanck, Marie;
    • Hilliard, Austin T.;
    • Klarin, Derek;
    • Damrauer, Scott M.;
    • Ho, Yuk-Lam;
    • Wilson, Peter W. F.;
    • Chang, Kyong-Mi;
    • Tsao, Philip S.;
    • Cho, Kelly;
    • O'Donnell, Christopher J.
    Publication type:
    Article
    21

    Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits.

    Published in:
    Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00773-z
    By:
    • Bone, William P.;
    • Siewert, Katherine M.;
    • Jha, Anupama;
    • Klarin, Derek;
    • Damrauer, Scott M.;
    • The VA Million Veteran Program;
    • Ballas, Zuhair K.;
    • Bhushan, Sujata;
    • Boyko, Edward J.;
    • Cohen, David M.;
    • Concato, John;
    • Constans, Joseph I.;
    • Dellitalia, Louis J.;
    • Fayad, Joseph M.;
    • Fernando, Ronald S.;
    • Florez, Hermes J.;
    • Gaddy, Melinda A.;
    • Gappy, Saib S.;
    • Gibson, Gretchen;
    • Godschalk, Michael
    Publication type:
    Article
    22

    PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.

    Published in:
    PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0239752
    By:
    • Small, Aeron M.;
    • Huffman, Jennifer E.;
    • Klarin, Derek;
    • Lynch, Julie A.;
    • Assimes, Themistocles;
    • DuVall, Scott;
    • Sun, Yan V.;
    • Shere, Labiba;
    • Natarajan, Pradeep;
    • Gaziano, Michael;
    • Rader, Daniel J.;
    • Wilson, Peter W. F.;
    • Tsao, Philip S.;
    • Chang, Kyong-Mi;
    • Cho, Kelly;
    • O'Donnell, Christopher J.;
    • Casas, Juan P.;
    • Damrauer, Scott M.
    Publication type:
    Article
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    DNA Sequence Variation in Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.

    Published in:
    2019
    By:
    • Emdin, Connor A.;
    • Khera, Amit V.;
    • Aragam, Krishna;
    • Haas, Mary;
    • Chaffin, Mark;
    • Klarin, Derek;
    • Natarajan, Pradeep;
    • Bick, Alexander;
    • Zekavat, Seyedeh M.;
    • Akihiro Nomura;
    • Ardissino, Diego;
    • Wilson, James G.;
    • Schunkert, Heribert;
    • McPherson, Ruth;
    • Watkins, Hugh;
    • Elosua, Roberto;
    • Bown, Matthew J.;
    • Samani, Nilesh J.;
    • Baber, Usman;
    • Erdmann, Jeanette
    Publication type:
    journal article
    25

    Gene-gene Interaction Analyses for Atrial Fibrillation.

    Published in:
    Scientific Reports, 2016, p. 35371, doi. 10.1038/srep35371
    By:
    • Lin, Honghuang;
    • Mueller-Nurasyid, Martina;
    • Smith, Albert V.;
    • Arking, Dan E.;
    • Barnard, John;
    • Bartz, Traci M.;
    • Lunetta, Kathryn L.;
    • Lohman, Kurt;
    • Kleber, Marcus E.;
    • Lubitz, Steven A.;
    • Geelhoed, Bastiaan;
    • Trompet, Stella;
    • Niemeijer, Maartje N.;
    • Kacprowski, Tim;
    • Chasman, Daniel I.;
    • Klarin, Derek;
    • Sinner, Moritz F.;
    • Waldenberger, Melanie;
    • Meitinger, Thomas;
    • Harris, Tamara B.
    Publication type:
    Article
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    Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11704-w
    By:
    • Hellwege, Jacklyn N.;
    • Velez Edwards, Digna R.;
    • Giri, Ayush;
    • Qiu, Chengxiang;
    • Park, Jihwan;
    • Torstenson, Eric S.;
    • Keaton, Jacob M.;
    • Wilson, O. D.;
    • Robinson-Cohen, Cassianne;
    • Chung, Cecilia P.;
    • Roumie, Christianne L.;
    • Klarin, Derek;
    • Damrauer, Scott M.;
    • DuVall, Scott L.;
    • Siew, Edward;
    • Akwo, Elvis A.;
    • Wuttke, Matthias;
    • Gorski, Mathias;
    • Li, Man;
    • Li, Yong
    Publication type:
    Article
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    Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09480-8
    By:
    • Kranzler, Henry R.;
    • Zhou, Hang;
    • Kember, Rachel L.;
    • Vickers Smith, Rachel;
    • Justice, Amy C.;
    • Damrauer, Scott;
    • Tsao, Philip S.;
    • Klarin, Derek;
    • Baras, Aris;
    • Reid, Jeffrey;
    • Overton, John;
    • Rader, Daniel J.;
    • Cheng, Zhongshan;
    • Tate, Janet P.;
    • Becker, William C.;
    • Concato, John;
    • Xu, Ke;
    • Polimanti, Renato;
    • Zhao, Hongyu;
    • Gelernter, Joel
    Publication type:
    Article
    30

    Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.

    Published in:
    Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02837-1
    By:
    • Kanoni, Stavroula;
    • Graham, Sarah E.;
    • Wang, Yuxuan;
    • Surakka, Ida;
    • Ramdas, Shweta;
    • Zhu, Xiang;
    • Clarke, Shoa L.;
    • Bhatti, Konain Fatima;
    • Vedantam, Sailaja;
    • Winkler, Thomas W.;
    • Locke, Adam E.;
    • Marouli, Eirini;
    • Zajac, Greg J. M.;
    • Wu, Kuan-Han H.;
    • Ntalla, Ioanna;
    • Hui, Qin;
    • Klarin, Derek;
    • Hilliard, Austin T.;
    • Wang, Zeyuan;
    • Xue, Chao
    Publication type:
    Article